Drosophila melanogaster

25 known processes

Epac (Dmel_CG34392)

CG34392 gene product from transcript CG34392-RC

(Aliases: Dmel_CG3427,CG15235,CG34392,Dmel_CG15235,Dmel\CG34392,D-EPAC,epac,CG3427)

Epac biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
insecticide metabolic process GO:0017143 2 0.263
steroid catabolic process GO:0006706 1 0.242
regulation of growth GO:0040008 233 0.203
medium chain fatty acid metabolic process GO:0051791 1 0.198
polyol biosynthetic process GO:0046173 3 0.197
xenobiotic catabolic process GO:0042178 1 0.192
secondary metabolic process GO:0019748 75 0.176
toxin metabolic process GO:0009404 2 0.163
catabolic process GO:0009056 409 0.163
fat soluble vitamin biosynthetic process GO:0042362 1 0.156
toxin catabolic process GO:0009407 1 0.145
single organism behavior GO:0044708 391 0.143
response to mercury ion GO:0046689 3 0.140
vitamin metabolic process GO:0006766 2 0.130
carboxylic acid metabolic process GO:0019752 92 0.123
defense response GO:0006952 300 0.121
anion homeostasis GO:0055081 3 0.120
response to abiotic stimulus GO:0009628 341 0.115
fat soluble vitamin metabolic process GO:0006775 1 0.111
secondary metabolite catabolic process GO:0090487 1 0.111
vitamin biosynthetic process GO:0009110 1 0.110
sensory perception GO:0007600 196 0.109
response to temperature stimulus GO:0009266 106 0.105
positive regulation of multicellular organismal process GO:0051240 143 0.104
response to biotic stimulus GO:0009607 294 0.103
positive regulation of macromolecule metabolic process GO:0010604 405 0.103
cellular ketone metabolic process GO:0042180 24 0.091
neurological system process GO:0050877 358 0.086
single organism biosynthetic process GO:0044711 206 0.086
developmental growth GO:0048589 280 0.085
organonitrogen compound metabolic process GO:1901564 318 0.085
regulation of hormone levels GO:0010817 40 0.082
positive regulation of gene expression GO:0010628 290 0.081
small molecule metabolic process GO:0044281 305 0.079
cellular catabolic process GO:0044248 372 0.071
growth GO:0040007 359 0.070
regionalization GO:0003002 416 0.069
response to bacterium GO:0009617 198 0.069
response to organophosphorus GO:0046683 2 0.065
oxoacid metabolic process GO:0043436 103 0.065
cellular ion homeostasis GO:0006873 39 0.064
organic acid metabolic process GO:0006082 103 0.062
lipid biosynthetic process GO:0008610 46 0.061
intracellular transport GO:0046907 228 0.061
response to other organism GO:0051707 293 0.061
hormone metabolic process GO:0042445 33 0.060
defense response to bacterium GO:0042742 178 0.059
organic hydroxy compound biosynthetic process GO:1901617 21 0.057
homeostatic process GO:0042592 199 0.055
response to caffeine GO:0031000 12 0.054
organic cyclic compound catabolic process GO:1901361 168 0.053
response to inorganic substance GO:0010035 44 0.052
response to external biotic stimulus GO:0043207 293 0.052
aggressive behavior GO:0002118 63 0.052
circulatory system process GO:0003013 37 0.051
establishment of localization in cell GO:0051649 402 0.050
defense response to other organism GO:0098542 225 0.050
lipid catabolic process GO:0016042 21 0.048
intracellular signal transduction GO:0035556 300 0.048
regulation of localization GO:0032879 275 0.048
regulation of anatomical structure size GO:0090066 163 0.045
organic substance catabolic process GO:1901575 308 0.045
cellular nitrogen compound catabolic process GO:0044270 165 0.043
organic hydroxy compound metabolic process GO:1901615 83 0.043
organic substance transport GO:0071702 257 0.042
phosphorylation GO:0016310 294 0.042
response to alkaloid GO:0043279 26 0.042
vesicle mediated transport GO:0016192 381 0.041
endocytosis GO:0006897 310 0.040
cell death GO:0008219 279 0.040
terpenoid metabolic process GO:0006721 7 0.039
cellular lipid metabolic process GO:0044255 83 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.038
regulation of tube size GO:0035150 46 0.038
transcription from rna polymerase ii promoter GO:0006366 368 0.038
single organism intracellular transport GO:1902582 207 0.038
response to endogenous stimulus GO:0009719 119 0.038
regulation of developmental growth GO:0048638 174 0.037
cellular chemical homeostasis GO:0055082 40 0.037
regulation of nervous system development GO:0051960 248 0.036
hormone biosynthetic process GO:0042446 20 0.035
regulation of cell differentiation GO:0045595 302 0.035
macromolecular complex assembly GO:0065003 256 0.035
response to cadmium ion GO:0046686 9 0.035
response to organic substance GO:0010033 284 0.034
regulation of cell cycle GO:0051726 291 0.034
cellular response to chemical stimulus GO:0070887 199 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
steroid biosynthetic process GO:0006694 16 0.033
response to nitrogen compound GO:1901698 90 0.032
positive regulation of biosynthetic process GO:0009891 316 0.032
isoprenoid metabolic process GO:0006720 8 0.031
lipid metabolic process GO:0006629 121 0.031
response to organonitrogen compound GO:0010243 75 0.030
oxidation reduction process GO:0055114 123 0.030
response to insecticide GO:0017085 14 0.030
regulation of protein metabolic process GO:0051246 256 0.030
regulation of blood circulation GO:1903522 21 0.030
single organism catabolic process GO:0044712 228 0.030
organonitrogen compound catabolic process GO:1901565 128 0.029
programmed cell death GO:0012501 257 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
defense response to gram negative bacterium GO:0050829 94 0.028
chromosome organization GO:0051276 360 0.028
alcohol metabolic process GO:0006066 25 0.028
cellular hormone metabolic process GO:0034754 23 0.028
ecdysone metabolic process GO:0008205 11 0.028
negative regulation of gene expression GO:0010629 387 0.028
death GO:0016265 284 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
compound eye development GO:0048749 307 0.027
chemical homeostasis GO:0048878 92 0.027
regulation of transport GO:0051049 181 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
segmentation GO:0035282 207 0.026
response to nutrient levels GO:0031667 114 0.026
regulation of system process GO:0044057 36 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
response to drug GO:0042493 17 0.024
negative regulation of developmental process GO:0051093 201 0.024
cellular macromolecule localization GO:0070727 220 0.024
positive regulation of signaling GO:0023056 243 0.024
fatty acid metabolic process GO:0006631 20 0.024
body morphogenesis GO:0010171 2 0.024
embryonic pattern specification GO:0009880 174 0.024
regulation of catabolic process GO:0009894 170 0.024
proteolysis GO:0006508 192 0.024
protein complex assembly GO:0006461 200 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
eye development GO:0001654 323 0.023
response to lipopolysaccharide GO:0032496 4 0.023
oocyte development GO:0048599 124 0.023
cytoplasmic transport GO:0016482 130 0.023
establishment of protein localization GO:0045184 163 0.023
small molecule biosynthetic process GO:0044283 37 0.023
response to organic cyclic compound GO:0014070 89 0.023
ecdysteroid metabolic process GO:0045455 19 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
appendage morphogenesis GO:0035107 397 0.022
nuclear division GO:0000280 332 0.022
response to toxic substance GO:0009636 22 0.022
developmental programmed cell death GO:0010623 138 0.022
axis specification GO:0009798 167 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
regulation of response to stress GO:0080134 200 0.022
response to metal ion GO:0010038 23 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.021
response to purine containing compound GO:0014074 12 0.021
response to xenobiotic stimulus GO:0009410 5 0.021
protein localization GO:0008104 284 0.021
organonitrogen compound biosynthetic process GO:1901566 117 0.021
anterior posterior pattern specification GO:0009952 136 0.021
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
protein modification process GO:0036211 438 0.021
cellular protein modification process GO:0006464 438 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
wing disc morphogenesis GO:0007472 344 0.020
protein transport GO:0015031 155 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
organelle fission GO:0048285 340 0.020
regulation of phosphorylation GO:0042325 147 0.020
dendrite morphogenesis GO:0048813 199 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
mesoderm development GO:0007498 78 0.020
protein complex biogenesis GO:0070271 201 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
cellular amide metabolic process GO:0043603 80 0.019
regulation of cell development GO:0060284 215 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
regulation of cell cycle process GO:0010564 181 0.019
cell proliferation GO:0008283 299 0.019
aromatic compound catabolic process GO:0019439 166 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
cell cycle phase transition GO:0044770 140 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
single organism cellular localization GO:1902580 180 0.018
immune system process GO:0002376 347 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
regulation of multi organism process GO:0043900 131 0.018
kidney development GO:0001822 3 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
response to transition metal nanoparticle GO:1990267 9 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
dna metabolic process GO:0006259 227 0.018
multi organism behavior GO:0051705 175 0.018
regulation of programmed cell death GO:0043067 152 0.018
dna packaging GO:0006323 91 0.018
exocrine system development GO:0035272 162 0.017
intracellular protein transport GO:0006886 104 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
open tracheal system development GO:0007424 204 0.017
steroid metabolic process GO:0008202 20 0.017
positive regulation of signal transduction GO:0009967 223 0.017
dna conformation change GO:0071103 105 0.017
peptide metabolic process GO:0006518 80 0.017
apoptotic process GO:0006915 159 0.017
positive regulation of cell communication GO:0010647 250 0.017
appendage development GO:0048736 401 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
dorsal ventral pattern formation GO:0009953 133 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
heterocycle catabolic process GO:0046700 166 0.016
negative regulation of cell communication GO:0010648 223 0.016
phagocytosis GO:0006909 215 0.016
memory GO:0007613 94 0.016
monocarboxylic acid metabolic process GO:0032787 29 0.016
regulation of cellular localization GO:0060341 136 0.016
salivary gland development GO:0007431 162 0.016
aging GO:0007568 143 0.016
compound eye morphogenesis GO:0001745 249 0.016
response to hormone GO:0009725 45 0.016
macromolecule catabolic process GO:0009057 161 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
protein phosphorylation GO:0006468 169 0.016
oocyte differentiation GO:0009994 145 0.016
behavioral response to ethanol GO:0048149 49 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
response to hypoxia GO:0001666 53 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
mapk cascade GO:0000165 107 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
chromosome segregation GO:0007059 157 0.015
salivary gland morphogenesis GO:0007435 145 0.015
spermatogenesis GO:0007283 200 0.015
sterol metabolic process GO:0016125 12 0.015
anterior posterior axis specification GO:0009948 109 0.015
gland development GO:0048732 191 0.015
regulation of immune response GO:0050776 118 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
forebrain development GO:0030900 2 0.015
imaginal disc pattern formation GO:0007447 91 0.015
embryonic axis specification GO:0000578 107 0.015
secretion GO:0046903 109 0.015
hormone catabolic process GO:0042447 3 0.015
negative regulation of cell cycle GO:0045786 116 0.015
ecdysteroid biosynthetic process GO:0045456 15 0.014
response to oxygen containing compound GO:1901700 200 0.014
localization of cell GO:0051674 257 0.014
cellular protein localization GO:0034613 160 0.014
cellular homeostasis GO:0019725 80 0.014
male gamete generation GO:0048232 201 0.014
chemotaxis GO:0006935 249 0.014
single organism membrane organization GO:0044802 93 0.014
tripartite regional subdivision GO:0007351 103 0.014
regulation of mapk cascade GO:0043408 92 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
response to lipid GO:0033993 38 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
eye morphogenesis GO:0048592 260 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.014
regulation of apoptotic process GO:0042981 130 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
dendrite development GO:0016358 204 0.014
cytoplasm organization GO:0007028 64 0.014
response to decreased oxygen levels GO:0036293 58 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of neurogenesis GO:0050767 158 0.013
tube morphogenesis GO:0035239 191 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
adult behavior GO:0030534 137 0.013
regulation of oocyte development GO:0060281 27 0.013
actin filament based process GO:0030029 220 0.013
response to monosaccharide GO:0034284 4 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
histolysis GO:0007559 102 0.013
cuticle development GO:0042335 86 0.013
rna localization GO:0006403 115 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
digestive tract morphogenesis GO:0048546 127 0.013
cell maturation GO:0048469 144 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
protein catabolic process GO:0030163 101 0.013
taxis GO:0042330 304 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
chromatin assembly or disassembly GO:0006333 52 0.013
regulation of secretion by cell GO:1903530 39 0.013
response to ethanol GO:0045471 59 0.013
monocarboxylic acid transport GO:0015718 3 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
autophagy GO:0006914 108 0.013
thermosensory behavior GO:0040040 19 0.013
regulation of neuron projection development GO:0010975 69 0.013
protein ubiquitination GO:0016567 70 0.012
regulation of reproductive process GO:2000241 54 0.012
regulation of protein modification process GO:0031399 112 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
cellular amine metabolic process GO:0044106 12 0.012
synaptic growth at neuromuscular junction GO:0051124 119 0.012
negative regulation of signal transduction GO:0009968 206 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
regulation of immune system process GO:0002682 176 0.012
cell migration GO:0016477 238 0.012
chromatin organization GO:0006325 207 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
amine metabolic process GO:0009308 12 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
gastrulation GO:0007369 70 0.012
respiratory system development GO:0060541 213 0.012
response to alcohol GO:0097305 95 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
organophosphate metabolic process GO:0019637 195 0.012
peptidyl amino acid modification GO:0018193 105 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
muscle structure development GO:0061061 224 0.012
regulation of molecular function GO:0065009 217 0.012
negative regulation of signaling GO:0023057 219 0.012
androgen metabolic process GO:0008209 1 0.012
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
cellular response to radiation GO:0071478 52 0.011
ameboidal type cell migration GO:0001667 151 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
immune response GO:0006955 246 0.011
regulation of catalytic activity GO:0050790 185 0.011
synaptic vesicle transport GO:0048489 50 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
meiotic cell cycle process GO:1903046 132 0.011
regulation of cell maturation GO:1903429 27 0.011
regulation of cell proliferation GO:0042127 163 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
secretion by cell GO:0032940 101 0.011
positive regulation of cell migration GO:0030335 2 0.011
cognition GO:0050890 141 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
xenobiotic metabolic process GO:0006805 5 0.011
glutathione metabolic process GO:0006749 37 0.011
actin cytoskeleton organization GO:0030036 206 0.011
cellular response to xenobiotic stimulus GO:0071466 5 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
immune response activating signal transduction GO:0002757 2 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
response to glucose GO:0009749 2 0.011
positive regulation of catabolic process GO:0009896 105 0.011
membrane organization GO:0061024 112 0.011
spindle organization GO:0007051 253 0.011
regulation of cell projection organization GO:0031344 92 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
central nervous system development GO:0007417 201 0.011
response to radiation GO:0009314 155 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
blastoderm segmentation GO:0007350 159 0.011
autophagic cell death GO:0048102 83 0.011
connective tissue development GO:0061448 3 0.011
camera type eye development GO:0043010 4 0.011
response to fungus GO:0009620 50 0.011
epithelial cell migration GO:0010631 148 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
digestive system development GO:0055123 149 0.010
response to light stimulus GO:0009416 124 0.010
response to hexose GO:0009746 3 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
negative regulation of nervous system development GO:0051961 92 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
pole plasm oskar mrna localization GO:0045451 46 0.010
sex differentiation GO:0007548 81 0.010
response to heat GO:0009408 63 0.010
salivary gland histolysis GO:0035070 88 0.010
regulation of cell death GO:0010941 173 0.010
negative regulation of phosphorylation GO:0042326 35 0.010

Epac disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.251
artery disease DOID:0050828 0 0.251
cardiovascular system disease DOID:1287 0 0.251
vascular disease DOID:178 0 0.251
hypertension DOID:10763 0 0.191
essential hypertension DOID:10825 0 0.185
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.011
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010