Drosophila melanogaster

43 known processes

Pde11 (Dmel_CG34341)

Phosphodiesterase 11

(Aliases: Dmel_CG15159,Dmel\CG34341,Dmel_CG10231,CG34341,CG10231,CG15159,PDE11)

Pde11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling involved in cell fate commitment GO:0045168 210 0.824
lateral inhibition GO:0046331 206 0.760
actin filament bundle assembly GO:0051017 26 0.195
regulation of response to stress GO:0080134 200 0.123
Rat
negative regulation of cell communication GO:0010648 223 0.117
actin filament bundle organization GO:0061572 28 0.117
long term memory GO:0007616 62 0.102
signal transduction by phosphorylation GO:0023014 107 0.091
Mouse
morphogenesis of an epithelium GO:0002009 276 0.089
organophosphate metabolic process GO:0019637 195 0.086
regulation of growth GO:0040008 233 0.084
positive regulation of signaling GO:0023056 243 0.076
Mouse
positive regulation of developmental process GO:0051094 143 0.074
Mouse
memory GO:0007613 94 0.073
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.071
single organism cellular localization GO:1902580 180 0.071
single organism membrane organization GO:0044802 93 0.070
carbohydrate derivative metabolic process GO:1901135 217 0.069
negative regulation of nucleic acid templated transcription GO:1903507 240 0.068
intracellular signal transduction GO:0035556 300 0.068
Mouse
negative regulation of signaling GO:0023057 219 0.068
nucleobase containing small molecule metabolic process GO:0055086 174 0.066
regulation of cellular component biogenesis GO:0044087 201 0.065
negative regulation of cellular metabolic process GO:0031324 382 0.065
epithelial tube morphogenesis GO:0060562 88 0.065
cognition GO:0050890 141 0.064
Rat
membrane organization GO:0061024 112 0.063
actin filament organization GO:0007015 126 0.061
regulation of cytoskeleton organization GO:0051493 89 0.059
regulation of defense response GO:0031347 102 0.059
Rat
central nervous system development GO:0007417 201 0.058
positive regulation of response to stimulus GO:0048584 323 0.057
Mouse Rat
regulation of gene expression epigenetic GO:0040029 128 0.056
regulation of localization GO:0032879 275 0.056
Fly
organonitrogen compound metabolic process GO:1901564 318 0.056
cellular macromolecule localization GO:0070727 220 0.055
endocytosis GO:0006897 310 0.054
tissue morphogenesis GO:0048729 297 0.054
epithelial cell differentiation GO:0030855 322 0.054
immune system process GO:0002376 347 0.053
Mouse
regulation of cell development GO:0060284 215 0.052
Mouse
intracellular transport GO:0046907 228 0.052
regulation of transport GO:0051049 181 0.051
Fly
small molecule metabolic process GO:0044281 305 0.051
positive regulation of cell communication GO:0010647 250 0.050
Mouse
positive regulation of signal transduction GO:0009967 223 0.050
Mouse
phosphorylation GO:0016310 294 0.048
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.047
post embryonic appendage morphogenesis GO:0035120 385 0.046
locomotory behavior GO:0007626 176 0.046
negative regulation of rna biosynthetic process GO:1902679 240 0.046
learning or memory GO:0007611 141 0.046
Rat
immune response GO:0006955 246 0.046
positive regulation of cellular component organization GO:0051130 156 0.044
embryonic morphogenesis GO:0048598 206 0.043
regulation of multicellular organismal development GO:2000026 414 0.043
actin filament based process GO:0030029 220 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.042
vesicle mediated transport GO:0016192 381 0.041
appendage morphogenesis GO:0035107 397 0.041
imaginal disc derived appendage morphogenesis GO:0035114 395 0.041
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
cellular protein localization GO:0034613 160 0.040
negative regulation of biosynthetic process GO:0009890 277 0.040
nucleoside phosphate metabolic process GO:0006753 162 0.040
establishment of localization in cell GO:0051649 402 0.040
compound eye development GO:0048749 307 0.039
regulation of organelle organization GO:0033043 196 0.039
spermatogenesis GO:0007283 200 0.038
regulation of cellular ketone metabolic process GO:0010565 3 0.038
regulation of actin filament based process GO:0032970 42 0.038
embryonic development via the syncytial blastoderm GO:0001700 148 0.038
synapse organization GO:0050808 196 0.037
macromolecular complex assembly GO:0065003 256 0.036
negative regulation of signal transduction GO:0009968 206 0.036
columnar cuboidal epithelial cell development GO:0002066 249 0.035
mitotic spindle organization GO:0007052 220 0.035
negative regulation of response to stimulus GO:0048585 258 0.035
wing disc morphogenesis GO:0007472 344 0.035
purine ribonucleoside catabolic process GO:0046130 112 0.034
telencephalon development GO:0021537 2 0.034
imaginal disc derived appendage development GO:0048737 399 0.034
forebrain development GO:0030900 2 0.033
localization of cell GO:0051674 257 0.033
regulation of molecular function GO:0065009 217 0.033
Mouse
ion transmembrane transport GO:0034220 122 0.033
head development GO:0060322 135 0.032
chromosome organization GO:0051276 360 0.032
positive regulation of rna metabolic process GO:0051254 271 0.032
homeostatic process GO:0042592 199 0.032
developmental maturation GO:0021700 172 0.032
negative regulation of cellular component organization GO:0051129 108 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
dendrite development GO:0016358 204 0.031
synapse assembly GO:0007416 143 0.031
negative regulation of gene expression GO:0010629 387 0.031
ion transport GO:0006811 145 0.030
purine nucleotide catabolic process GO:0006195 109 0.030
Human Mouse
dna metabolic process GO:0006259 227 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
single organism behavior GO:0044708 391 0.030
Rat
nucleoside triphosphate metabolic process GO:0009141 120 0.030
protein localization GO:0008104 284 0.029
receptor clustering GO:0043113 3 0.029
regulation of synapse organization GO:0050807 110 0.029
negative regulation of cytoskeleton organization GO:0051494 30 0.029
morphogenesis of embryonic epithelium GO:0016331 94 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
actin cytoskeleton organization GO:0030036 206 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.027
positive regulation of cell development GO:0010720 61 0.027
Mouse
positive regulation of cell differentiation GO:0045597 64 0.026
Mouse
eye morphogenesis GO:0048592 260 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
purine ribonucleotide catabolic process GO:0009154 109 0.026
Human Mouse
protein complex biogenesis GO:0070271 201 0.026
male gamete generation GO:0048232 201 0.026
growth GO:0040007 359 0.025
salivary gland morphogenesis GO:0007435 145 0.025
regulation of actin cytoskeleton organization GO:0032956 42 0.025
positive regulation of transport GO:0051050 92 0.025
ovarian follicle cell development GO:0030707 248 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.025
Human Mouse
organelle localization GO:0051640 148 0.025
translation GO:0006412 69 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
regulation of protein metabolic process GO:0051246 256 0.025
Mouse
response to nutrient levels GO:0031667 114 0.025
golgi vesicle transport GO:0048193 27 0.024
negative regulation of organelle organization GO:0010639 56 0.024
single organism intracellular transport GO:1902582 207 0.024
appendage development GO:0048736 401 0.024
positive regulation of nervous system development GO:0051962 69 0.024
nucleoside metabolic process GO:0009116 127 0.024
catabolic process GO:0009056 409 0.024
Human Mouse
spindle organization GO:0007051 253 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
Mouse Rat
endomembrane system organization GO:0010256 119 0.024
negative regulation of phosphorus metabolic process GO:0010563 45 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
chromatin organization GO:0006325 207 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
regulation of cell morphogenesis GO:0022604 163 0.023
nuclear division GO:0000280 332 0.023
regulation of mapk cascade GO:0043408 92 0.022
Mouse
organelle fission GO:0048285 340 0.022
regulation of cell cycle GO:0051726 291 0.022
gland development GO:0048732 191 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
phagocytosis GO:0006909 215 0.022
positive regulation of cell migration GO:0030335 2 0.022
cellular response to extracellular stimulus GO:0031668 64 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
membrane depolarization GO:0051899 4 0.022
positive regulation of neurogenesis GO:0050769 41 0.022
single organism biosynthetic process GO:0044711 206 0.022
adult behavior GO:0030534 137 0.022
associative learning GO:0008306 65 0.022
negative regulation of gene expression epigenetic GO:0045814 77 0.022
learning GO:0007612 75 0.022
regulation of catabolic process GO:0009894 170 0.022
protein complex assembly GO:0006461 200 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
positive regulation of cell motility GO:2000147 3 0.021
regionalization GO:0003002 416 0.021
taxis GO:0042330 304 0.021
secretion by cell GO:0032940 101 0.021
immune response activating signal transduction GO:0002757 2 0.021
regulation of cell differentiation GO:0045595 302 0.021
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.020
Mouse
purine containing compound metabolic process GO:0072521 155 0.020
heterocycle catabolic process GO:0046700 166 0.020
Human Mouse
brain development GO:0007420 120 0.020
camera type eye development GO:0043010 4 0.020
tube development GO:0035295 244 0.020
programmed cell death GO:0012501 257 0.020
Rat
aromatic compound catabolic process GO:0019439 166 0.020
Human Mouse
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.020
organic substance transport GO:0071702 257 0.020
Fly
single organism carbohydrate metabolic process GO:0044723 72 0.020
protein phosphorylation GO:0006468 169 0.020
Mouse
positive regulation of molecular function GO:0044093 136 0.019
Mouse
organic substance catabolic process GO:1901575 308 0.019
Human Mouse
response to abiotic stimulus GO:0009628 341 0.019
Rat
nucleoside catabolic process GO:0009164 112 0.019
ras protein signal transduction GO:0007265 88 0.019
protein modification process GO:0036211 438 0.019
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.019
cellular ketone metabolic process GO:0042180 24 0.019
regulation of response to external stimulus GO:0032101 115 0.019
Rat
response to lipopolysaccharide GO:0032496 4 0.019
Rat
sensory organ morphogenesis GO:0090596 260 0.019
response to monosaccharide GO:0034284 4 0.019
response to extracellular stimulus GO:0009991 116 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
exocrine system development GO:0035272 162 0.018
regulation of cell projection organization GO:0031344 92 0.018
chaeta development GO:0022416 97 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
Human Mouse
dendrite morphogenesis GO:0048813 199 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
covalent chromatin modification GO:0016569 106 0.018
embryonic pattern specification GO:0009880 174 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
cell cycle checkpoint GO:0000075 95 0.018
secretion GO:0046903 109 0.018
response to wounding GO:0009611 94 0.017
Rat
regulation of neuron differentiation GO:0045664 103 0.017
eye development GO:0001654 323 0.017
salivary gland development GO:0007431 162 0.017
response to biotic stimulus GO:0009607 294 0.017
Rat
purine ribonucleoside metabolic process GO:0046128 127 0.017
intracellular protein transport GO:0006886 104 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
single organism catabolic process GO:0044712 228 0.017
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
generation of precursor metabolites and energy GO:0006091 42 0.017
negative regulation of intracellular signal transduction GO:1902532 57 0.017
organophosphate catabolic process GO:0046434 112 0.016
Human Mouse
developmental growth GO:0048589 280 0.016
gland morphogenesis GO:0022612 145 0.016
oxoacid metabolic process GO:0043436 103 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
response to oxygen containing compound GO:1901700 200 0.016
Rat
ribonucleoside catabolic process GO:0042454 112 0.016
positive regulation of gene expression GO:0010628 290 0.016
regulation of catalytic activity GO:0050790 185 0.016
Mouse
cell motility GO:0048870 251 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
cell fate determination GO:0001709 91 0.016
regulation of cell proliferation GO:0042127 163 0.016
Mouse
amine metabolic process GO:0009308 12 0.016
response to other organism GO:0051707 293 0.016
Rat
nucleobase containing compound catabolic process GO:0034655 165 0.015
Human Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.015
regulation of vesicle mediated transport GO:0060627 59 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
Human Mouse
chromatin remodeling GO:0006338 72 0.015
gene silencing GO:0016458 138 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
nucleotide metabolic process GO:0009117 161 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
regulation of developmental growth GO:0048638 174 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
Mouse
g protein coupled receptor signaling pathway GO:0007186 136 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
rna processing GO:0006396 147 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
negative regulation of immune system process GO:0002683 50 0.015
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.015
Mouse
protein localization to membrane GO:0072657 19 0.015
meiotic nuclear division GO:0007126 151 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
negative regulation of cell cycle GO:0045786 116 0.015
regulation of cell cycle g1 s phase transition GO:1902806 23 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
peptidyl lysine modification GO:0018205 57 0.014
regulation of cell cycle process GO:0010564 181 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
purine containing compound catabolic process GO:0072523 112 0.014
Human Mouse
olfactory behavior GO:0042048 97 0.014
single organism membrane fusion GO:0044801 42 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of programmed cell death GO:0043067 152 0.014
Rat
positive regulation of cellular catabolic process GO:0031331 95 0.014
regulation of neurogenesis GO:0050767 158 0.014
mitotic nuclear division GO:0007067 213 0.014
humoral immune response GO:0006959 117 0.014
positive regulation of catabolic process GO:0009896 105 0.014
neuron neuron synaptic transmission GO:0007270 14 0.014
cellular amine metabolic process GO:0044106 12 0.014
death GO:0016265 284 0.014
Rat
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.014
protein localization to plasma membrane GO:0072659 13 0.013
compound eye morphogenesis GO:0001745 249 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
Mouse
mrna metabolic process GO:0016071 124 0.013
positive regulation of cell projection organization GO:0031346 29 0.013
detection of glucose GO:0051594 1 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
negative regulation of cell death GO:0060548 81 0.013
regulation of dendrite morphogenesis GO:0048814 28 0.013
digestive system development GO:0055123 149 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
Mouse
wnt signaling pathway GO:0016055 98 0.013
neuron recognition GO:0008038 101 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
Human Mouse
regulation of mrna processing GO:0050684 71 0.013
cellular homeostasis GO:0019725 80 0.013
axis specification GO:0009798 167 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
positive regulation of organelle organization GO:0010638 65 0.013
regulation of actin filament bundle assembly GO:0032231 8 0.012
blastoderm segmentation GO:0007350 159 0.012
epithelial cell development GO:0002064 274 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
mitochondrion organization GO:0007005 65 0.012
synaptic transmission GO:0007268 288 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of cellular response to stress GO:0080135 89 0.012
peptidyl amino acid modification GO:0018193 105 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
nucleotide catabolic process GO:0009166 109 0.012
Human Mouse
response to glucose GO:0009749 2 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
axon development GO:0061564 297 0.012
gtp metabolic process GO:0046039 72 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
Mouse
response to oxidative stress GO:0006979 86 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
imaginal disc pattern formation GO:0007447 91 0.012
immune system development GO:0002520 57 0.012
oxidoreduction coenzyme metabolic process GO:0006733 2 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
Human Mouse
cell cycle phase transition GO:0044770 140 0.012
axonogenesis GO:0007409 290 0.012
cuticle development GO:0042335 86 0.012
chromatin modification GO:0016568 147 0.012
mrna processing GO:0006397 104 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
organic acid metabolic process GO:0006082 103 0.012
response to radiation GO:0009314 155 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
nephron epithelium development GO:0072009 3 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
mesenchymal cell development GO:0014031 1 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
response to hexose GO:0009746 3 0.011
segmentation GO:0035282 207 0.011
cell cycle g1 s phase transition GO:0044843 31 0.011
innate immune response GO:0045087 144 0.011
filopodium assembly GO:0046847 33 0.011
retina development in camera type eye GO:0060041 4 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
regulation of protein modification process GO:0031399 112 0.011
Mouse
organelle fusion GO:0048284 46 0.011
regulation of cell death GO:0010941 173 0.011
Rat
synaptic growth at neuromuscular junction GO:0051124 119 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
regulation of ion transport GO:0043269 39 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
sister chromatid segregation GO:0000819 92 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
kidney development GO:0001822 3 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of membrane potential GO:0042391 35 0.011
meiotic cell cycle GO:0051321 171 0.011
protein transport GO:0015031 155 0.011
cell proliferation GO:0008283 299 0.011
Mouse
autophagy GO:0006914 108 0.011
histone modification GO:0016570 106 0.011
cellular response to nutrient levels GO:0031669 62 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
regulation of mrna metabolic process GO:1903311 72 0.010
gtp catabolic process GO:0006184 72 0.010
tube formation GO:0035148 21 0.010
mapk cascade GO:0000165 107 0.010
Mouse
negative regulation of programmed cell death GO:0043069 72 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
Mouse
convergent extension GO:0060026 2 0.010
hematopoietic or lymphoid organ development GO:0048534 57 0.010
chromosome segregation GO:0007059 157 0.010
digestive tract development GO:0048565 149 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
Mouse
cellular response to organic substance GO:0071310 132 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
anterior posterior pattern specification GO:0009952 136 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
chemosensory behavior GO:0007635 106 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
Mouse

Pde11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
acquired metabolic disease DOID:0060158 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.016
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.015
nervous system disease DOID:863 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
glucose metabolism disease DOID:4194 0 0.011
diabetes mellitus DOID:9351 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010