Drosophila melanogaster

0 known processes

PHDP (Dmel_CG11182)

Putative homeodomain protein

(Aliases: anon-60Ac,CG11182,Dmel\CG11182)

PHDP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.150
inter male aggressive behavior GO:0002121 60 0.101
camera type eye development GO:0043010 4 0.101
single organism behavior GO:0044708 391 0.099
positive regulation of macromolecule metabolic process GO:0010604 405 0.095
establishment of localization in cell GO:0051649 402 0.085
homeostatic process GO:0042592 199 0.085
spindle organization GO:0007051 253 0.073
regulation of mitotic cell cycle GO:0007346 190 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.065
multi organism behavior GO:0051705 175 0.065
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.063
locomotory behavior GO:0007626 176 0.063
tissue morphogenesis GO:0048729 297 0.062
cellular protein modification process GO:0006464 438 0.056
actin filament based process GO:0030029 220 0.055
forebrain development GO:0030900 2 0.055
organophosphate metabolic process GO:0019637 195 0.054
regulation of cell cycle GO:0051726 291 0.053
regulation of cellular protein metabolic process GO:0032268 243 0.053
positive regulation of rna metabolic process GO:0051254 271 0.052
immune system process GO:0002376 347 0.051
protein modification process GO:0036211 438 0.051
spinal cord development GO:0021510 1 0.046
regulation of anatomical structure size GO:0090066 163 0.046
telencephalon development GO:0021537 2 0.044
actomyosin structure organization GO:0031032 56 0.044
transcription from rna polymerase ii promoter GO:0006366 368 0.044
response to oxygen containing compound GO:1901700 200 0.042
phagocytosis GO:0006909 215 0.041
regulation of anatomical structure morphogenesis GO:0022603 242 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.039
endocytosis GO:0006897 310 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.038
multicellular organismal aging GO:0010259 140 0.037
phosphorylation GO:0016310 294 0.036
positive regulation of transcription dna templated GO:0045893 266 0.036
chemotaxis GO:0006935 249 0.035
establishment of synaptic vesicle localization GO:0097480 50 0.035
negative regulation of mitotic cell cycle GO:0045930 109 0.034
negative regulation of cell cycle GO:0045786 116 0.034
positive regulation of gene expression GO:0010628 290 0.033
actin cytoskeleton organization GO:0030036 206 0.033
secretion by cell GO:0032940 101 0.033
cell proliferation GO:0008283 299 0.033
ocellus pigment metabolic process GO:0046158 19 0.032
small molecule metabolic process GO:0044281 305 0.032
cell death GO:0008219 279 0.032
response to monosaccharide GO:0034284 4 0.032
regulation of catalytic activity GO:0050790 185 0.031
regulation of nervous system development GO:0051960 248 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
kidney development GO:0001822 3 0.031
cell junction organization GO:0034330 57 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.030
eye development GO:0001654 323 0.030
aggressive behavior GO:0002118 63 0.030
regulation of programmed cell death GO:0043067 152 0.030
eye photoreceptor cell differentiation GO:0001754 145 0.030
eye morphogenesis GO:0048592 260 0.030
intracellular transport GO:0046907 228 0.029
connective tissue development GO:0061448 3 0.029
cellular macromolecule localization GO:0070727 220 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
cellular response to chemical stimulus GO:0070887 199 0.028
gland development GO:0048732 191 0.028
developmental programmed cell death GO:0010623 138 0.028
leg disc development GO:0035218 92 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.027
response to organic substance GO:0010033 284 0.027
neurological system process GO:0050877 358 0.027
cellular response to dna damage stimulus GO:0006974 223 0.026
synaptic transmission GO:0007268 288 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.026
negative regulation of cell proliferation GO:0008285 69 0.026
chemical homeostasis GO:0048878 92 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
taxis GO:0042330 304 0.025
camera type eye morphogenesis GO:0048593 2 0.025
exocrine system development GO:0035272 162 0.025
ommochrome biosynthetic process GO:0006727 19 0.024
regulation of neurogenesis GO:0050767 158 0.024
anterior posterior pattern specification GO:0009952 136 0.024
macromolecular complex assembly GO:0065003 256 0.024
regulation of cell differentiation GO:0045595 302 0.024
brain development GO:0007420 120 0.024
biological adhesion GO:0022610 138 0.024
regulation of cell cycle process GO:0010564 181 0.024
positive regulation of cell communication GO:0010647 250 0.023
neuron projection guidance GO:0097485 241 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
establishment of organelle localization GO:0051656 122 0.023
single organism biosynthetic process GO:0044711 206 0.022
locomotor rhythm GO:0045475 56 0.022
segmentation GO:0035282 207 0.022
synaptic vesicle localization GO:0097479 53 0.022
rhythmic process GO:0048511 106 0.022
reproductive behavior GO:0019098 122 0.022
secretion GO:0046903 109 0.022
single organism intracellular transport GO:1902582 207 0.022
rhythmic behavior GO:0007622 76 0.021
learning or memory GO:0007611 141 0.021
response to glucose GO:0009749 2 0.021
renal system development GO:0072001 72 0.021
death GO:0016265 284 0.021
protein phosphorylation GO:0006468 169 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.020
cell cell junction organization GO:0045216 55 0.020
regulation of localization GO:0032879 275 0.020
nucleotide metabolic process GO:0009117 161 0.020
respiratory system development GO:0060541 213 0.020
neural precursor cell proliferation GO:0061351 75 0.020
gland morphogenesis GO:0022612 145 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
ocellus pigment biosynthetic process GO:0008055 19 0.020
epithelial tube morphogenesis GO:0060562 88 0.020
regulation of cell development GO:0060284 215 0.020
hindbrain development GO:0030902 2 0.020
central nervous system development GO:0007417 201 0.019
positive regulation of cell migration GO:0030335 2 0.019
regulation of cell proliferation GO:0042127 163 0.019
protein heterooligomerization GO:0051291 4 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
cellular protein localization GO:0034613 160 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
appendage development GO:0048736 401 0.018
regulation of cell projection organization GO:0031344 92 0.018
response to abiotic stimulus GO:0009628 341 0.018
nucleoside phosphate biosynthetic process GO:1901293 34 0.018
carbohydrate metabolic process GO:0005975 82 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
response to hexose GO:0009746 3 0.017
epithelial cell differentiation GO:0030855 322 0.017
regulation of protein metabolic process GO:0051246 256 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
salivary gland morphogenesis GO:0007435 145 0.017
regulation of cell fate commitment GO:0010453 29 0.017
regulation of neuron differentiation GO:0045664 103 0.017
regulation of gene silencing GO:0060968 63 0.017
protein maturation GO:0051604 71 0.017
regulation of molecular function GO:0065009 217 0.017
positive regulation of programmed cell death GO:0043068 62 0.016
regulation of cell death GO:0010941 173 0.016
meiosis i GO:0007127 59 0.016
adult locomotory behavior GO:0008344 76 0.016
eye antennal disc development GO:0035214 60 0.016
cellular response to carbohydrate stimulus GO:0071322 4 0.016
mesenchymal cell development GO:0014031 1 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
positive regulation of response to stimulus GO:0048584 323 0.015
memory GO:0007613 94 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
organelle assembly GO:0070925 198 0.015
cell adhesion GO:0007155 136 0.015
regulation of hydrolase activity GO:0051336 97 0.015
regulation of immune system process GO:0002682 176 0.015
negative regulation of neurogenesis GO:0050768 53 0.015
regulation of tube size open tracheal system GO:0035151 43 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
sensory organ morphogenesis GO:0090596 260 0.015
regulation of cell fate specification GO:0042659 27 0.015
response to organic cyclic compound GO:0014070 89 0.014
regulation of secretion by cell GO:1903530 39 0.014
embryonic morphogenesis GO:0048598 206 0.014
exocytosis GO:0006887 28 0.014
salivary gland development GO:0007431 162 0.014
ocellus pigmentation GO:0033060 19 0.014
rna processing GO:0006396 147 0.014
retina development in camera type eye GO:0060041 4 0.014
cell cycle phase transition GO:0044770 140 0.014
embryonic hindgut morphogenesis GO:0048619 48 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
urogenital system development GO:0001655 72 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
ion homeostasis GO:0050801 55 0.014
head development GO:0060322 135 0.014
nucleotide biosynthetic process GO:0009165 34 0.014
receptor clustering GO:0043113 3 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
cellular homeostasis GO:0019725 80 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
retina morphogenesis in camera type eye GO:0060042 2 0.013
response to external biotic stimulus GO:0043207 293 0.013
organelle fusion GO:0048284 46 0.013
establishment of vesicle localization GO:0051650 51 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
proteolysis GO:0006508 192 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
innate immune response GO:0045087 144 0.013
cytoplasmic transport GO:0016482 130 0.013
determination of adult lifespan GO:0008340 137 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
renal tubule development GO:0061326 64 0.013
rna localization GO:0006403 115 0.013
protein localization GO:0008104 284 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
leg disc morphogenesis GO:0007478 80 0.013
mitotic dna damage checkpoint GO:0044773 74 0.013
autophagic cell death GO:0048102 83 0.013
organophosphate biosynthetic process GO:0090407 46 0.013
notch signaling pathway GO:0007219 120 0.013
cation homeostasis GO:0055080 51 0.013
positive regulation of protein modification process GO:0031401 58 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
protein complex assembly GO:0006461 200 0.012
axis specification GO:0009798 167 0.012
cognition GO:0050890 141 0.012
negative regulation of homeostatic process GO:0032845 2 0.012
cellular amine metabolic process GO:0044106 12 0.012
response to alcohol GO:0097305 95 0.012
positive regulation of cell motility GO:2000147 3 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
regulation of defense response GO:0031347 102 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
positive regulation of transport GO:0051050 92 0.012
positive regulation of developmental process GO:0051094 143 0.012
dna damage checkpoint GO:0000077 78 0.012
endomembrane system organization GO:0010256 119 0.012
convergent extension GO:0060026 2 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
ommochrome metabolic process GO:0046152 19 0.012
neuron death GO:0070997 27 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.011
response to other organism GO:0051707 293 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
wound healing GO:0042060 75 0.011
dorsal ventral axis specification GO:0009950 66 0.011
amine metabolic process GO:0009308 12 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
open tracheal system development GO:0007424 204 0.011
multicellular organismal homeostasis GO:0048871 41 0.011
response to radiation GO:0009314 155 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
appendage morphogenesis GO:0035107 397 0.011
nephron development GO:0072006 3 0.011
regulation of apoptotic process GO:0042981 130 0.011
rna splicing GO:0008380 83 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
telomere maintenance GO:0000723 21 0.011
developmental maturation GO:0021700 172 0.011
single organism cellular localization GO:1902580 180 0.011
positive regulation of protein kinase activity GO:0045860 25 0.011
oocyte differentiation GO:0009994 145 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
alternative mrna splicing via spliceosome GO:0000380 60 0.011
positive regulation of signaling GO:0023056 243 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of immune response GO:0050776 118 0.011
golgi organization GO:0007030 66 0.011
positive regulation of immune response GO:0050778 63 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
cell division GO:0051301 248 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
tripartite regional subdivision GO:0007351 103 0.011
axon guidance GO:0007411 233 0.011
courtship behavior GO:0007619 68 0.011
positive regulation of nervous system development GO:0051962 69 0.011
regionalization GO:0003002 416 0.011
cell cycle checkpoint GO:0000075 95 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
anatomical structure homeostasis GO:0060249 97 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
secondary metabolite biosynthetic process GO:0044550 24 0.010
erbb signaling pathway GO:0038127 58 0.010
response to organophosphorus GO:0046683 2 0.010
organic substance transport GO:0071702 257 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
telomere maintenance via recombination GO:0000722 1 0.010
organelle localization GO:0051640 148 0.010
antennal development GO:0007469 25 0.010
chaeta development GO:0022416 97 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
cell junction assembly GO:0034329 42 0.010
metal ion homeostasis GO:0055065 44 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
malpighian tubule development GO:0072002 64 0.010

PHDP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.057
artery disease DOID:0050828 0 0.019
vascular disease DOID:178 0 0.019
cardiovascular system disease DOID:1287 0 0.019
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
renal tubular transport disease DOID:447 0 0.016
kidney disease DOID:557 0 0.016
urinary system disease DOID:18 0 0.016
disease of metabolism DOID:0014667 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012