Drosophila melanogaster

129 known processes

ash1 (Dmel_CG8887)

absent, small, or homeotic discs 1

(Aliases: dash,ash,CG8887,ash-1,l(3)SG29a,Ash 1,Ash1,Dmel\CG8887,Ash,ASH1)

ash1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin silencing GO:0006342 76 0.994
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.993
negative regulation of cellular biosynthetic process GO:0031327 277 0.988
negative regulation of rna biosynthetic process GO:1902679 240 0.988
chromatin remodeling GO:0006338 72 0.977
gene silencing GO:0016458 138 0.968
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.963
negative regulation of biosynthetic process GO:0009890 277 0.961
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.960
negative regulation of nucleic acid templated transcription GO:1903507 240 0.960
negative regulation of transcription dna templated GO:0045892 237 0.958
negative regulation of rna metabolic process GO:0051253 251 0.952
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.947
peptidyl lysine modification GO:0018205 57 0.946
transcription from rna polymerase ii promoter GO:0006366 368 0.940
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.935
protein dna complex subunit organization GO:0071824 86 0.922
nucleosome organization GO:0034728 59 0.907
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.861
Mouse
chromatin mediated maintenance of transcription GO:0048096 7 0.800
negative regulation of gene expression epigenetic GO:0045814 77 0.783
regionalization GO:0003002 416 0.747
methylation GO:0032259 47 0.744
chromosome organization GO:0051276 360 0.733
chromatin organization GO:0006325 207 0.729
chemotaxis GO:0006935 249 0.676
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.642
negative regulation of gene expression GO:0010629 387 0.629
protein acetylation GO:0006473 39 0.618
peptidyl lysine methylation GO:0018022 16 0.603
chromatin assembly or disassembly GO:0006333 52 0.571
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.542
regulation of cell morphogenesis GO:0022604 163 0.540
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.531
nucleosome positioning GO:0016584 3 0.471
internal protein amino acid acetylation GO:0006475 38 0.407
leg disc development GO:0035218 92 0.406
histone h3 k4 methylation GO:0051568 16 0.399
histone acetylation GO:0016573 38 0.398
regulation of response to gamma radiation GO:2001228 4 0.396
dna alkylation GO:0006305 4 0.372
histone h3 k9 acetylation GO:0043970 3 0.360
regulation of chromatin silencing GO:0031935 36 0.359
segmentation GO:0035282 207 0.338
dna methylation or demethylation GO:0044728 4 0.334
response to sterol GO:0036314 34 0.320
peptidyl lysine acetylation GO:0018394 39 0.319
positive regulation of rna biosynthetic process GO:1902680 266 0.311
central nervous system development GO:0007417 201 0.300
histone h3 k27 methylation GO:0070734 6 0.293
anterior posterior pattern specification GO:0009952 136 0.257
specification of segmental identity trunk GO:0035292 7 0.256
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.242
positive regulation of cellular biosynthetic process GO:0031328 316 0.236
regulation of cell proliferation GO:0042127 163 0.235
induction of programmed cell death by ecdysone GO:0035078 12 0.233
enzyme linked receptor protein signaling pathway GO:0007167 179 0.227
regulation of gene silencing GO:0060968 63 0.221
nucleosome mobilization GO:0042766 9 0.220
terminal region determination GO:0007362 25 0.215
protein acylation GO:0043543 42 0.211
positive regulation of transcription dna templated GO:0045893 266 0.211
dna methylation GO:0006306 4 0.203
dna metabolic process GO:0006259 227 0.196
protein alkylation GO:0008213 43 0.192
anterior posterior axis specification GO:0009948 109 0.190
imaginal disc derived leg morphogenesis GO:0007480 80 0.178
single organism biosynthetic process GO:0044711 206 0.174
protein modification by small protein removal GO:0070646 28 0.171
pupal development GO:0035209 11 0.161
histone modification GO:0016570 106 0.152
protein modification by small protein conjugation or removal GO:0070647 106 0.148
leg disc morphogenesis GO:0007478 80 0.144
regulation of cell differentiation GO:0045595 302 0.143
histone ubiquitination GO:0016574 4 0.139
covalent chromatin modification GO:0016569 106 0.131
taxis GO:0042330 304 0.131
mitotic chromosome condensation GO:0007076 22 0.130
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.127
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.126
positive regulation of nucleic acid templated transcription GO:1903508 266 0.124
regulation of histone modification GO:0031056 20 0.123
induction of programmed cell death by hormones GO:0035081 12 0.121
salivary gland cell autophagic cell death GO:0035071 83 0.120
positive regulation of macromolecule metabolic process GO:0010604 405 0.119
histone h3 acetylation GO:0043966 11 0.119
gland development GO:0048732 191 0.117
histone lysine methylation GO:0034968 32 0.114
negative regulation of signal transduction GO:0009968 206 0.112
Mouse
negative regulation of cellular component organization GO:0051129 108 0.109
positive regulation of gene expression epigenetic GO:0045815 16 0.108
histone h4 k16 acetylation GO:0043984 4 0.107
regulation of chromatin modification GO:1903308 28 0.106
torso signaling pathway GO:0008293 21 0.105
positive regulation of rna metabolic process GO:0051254 271 0.104
ovarian follicle cell stalk formation GO:0030713 17 0.102
response to abiotic stimulus GO:0009628 341 0.100
female germ line cyst encapsulation GO:0048139 8 0.095
male courtship behavior GO:0008049 63 0.091
negative regulation of cardiac cell fate specification GO:2000044 7 0.091
oocyte differentiation GO:0009994 145 0.090
protein deubiquitination GO:0016579 17 0.089
induction of programmed cell death GO:0012502 12 0.089
dendrite morphogenesis GO:0048813 199 0.085
positive regulation of cell cycle g2 m phase transition GO:1902751 2 0.084
negative regulation of cell differentiation GO:0045596 143 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.082
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.081
Mouse
autophagic cell death GO:0048102 83 0.079
protein modification process GO:0036211 438 0.079
negative regulation of chromatin silencing GO:0031936 9 0.079
fatty acid homeostasis GO:0055089 2 0.078
periodic partitioning GO:0007365 29 0.078
regulation of photoreceptor cell differentiation GO:0046532 34 0.074
positive regulation of stem cell differentiation GO:2000738 3 0.073
positive regulation of biosynthetic process GO:0009891 316 0.073
germarium derived female germ line cyst encapsulation GO:0030708 8 0.072
neuron projection guidance GO:0097485 241 0.071
positive regulation of cellular component organization GO:0051130 156 0.070
regulation of chromosome organization GO:0033044 64 0.070
gene silencing by rna GO:0031047 57 0.069
embryonic organ development GO:0048568 50 0.069
response to ecdysone GO:0035075 34 0.068
salivary gland histolysis GO:0035070 88 0.067
cell cycle phase transition GO:0044770 140 0.067
male gamete generation GO:0048232 201 0.066
ocellus pigment metabolic process GO:0046158 19 0.065
dna templated transcription elongation GO:0006354 18 0.064
salivary gland development GO:0007431 162 0.064
macromolecule methylation GO:0043414 45 0.062
positive regulation of gene expression GO:0010628 290 0.060
organelle fission GO:0048285 340 0.060
nucleoside triphosphate catabolic process GO:0009143 108 0.060
notch signaling pathway GO:0007219 120 0.060
skin development GO:0043588 65 0.059
imaginal disc derived appendage morphogenesis GO:0035114 395 0.059
dendrite development GO:0016358 204 0.059
trunk segmentation GO:0035290 8 0.059
axon guidance GO:0007411 233 0.058
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.058
positive regulation of cell death GO:0010942 69 0.058
forebrain development GO:0030900 2 0.056
pigmentation GO:0043473 75 0.056
peptidyl lysine trimethylation GO:0018023 6 0.054
single organism behavior GO:0044708 391 0.054
dna dependent dna replication GO:0006261 17 0.053
histone h4 k20 methylation GO:0034770 4 0.053
cellular response to hydrogen peroxide GO:0070301 7 0.051
response to alcohol GO:0097305 95 0.051
regulation of intracellular signal transduction GO:1902531 236 0.050
Mouse
negative regulation of cell communication GO:0010648 223 0.050
Mouse
larval development GO:0002164 104 0.050
regulation of notch signaling pathway GO:0008593 100 0.049
multi organism reproductive behavior GO:0044705 121 0.049
positive regulation of mrna metabolic process GO:1903313 5 0.049
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.048
Mouse
cellular protein modification process GO:0006464 438 0.048
negative regulation of cell proliferation GO:0008285 69 0.048
telencephalon development GO:0021537 2 0.047
negative regulation of neuroblast proliferation GO:0007406 27 0.046
tissue death GO:0016271 102 0.046
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.045
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.045
appendage development GO:0048736 401 0.045
histolysis GO:0007559 102 0.045
dna modification GO:0006304 5 0.044
regulation of anatomical structure morphogenesis GO:0022603 242 0.044
regulation of dna templated transcription in response to stress GO:0043620 4 0.043
cellular response to chemical stimulus GO:0070887 199 0.040
histone deubiquitination GO:0016578 8 0.040
extracellular matrix assembly GO:0085029 13 0.040
growth GO:0040007 359 0.039
positive regulation of signaling GO:0023056 243 0.038
cellular amine metabolic process GO:0044106 12 0.038
positive regulation of chromatin silencing GO:0031937 16 0.038
open tracheal system development GO:0007424 204 0.037
chromatin modification GO:0016568 147 0.036
axonogenesis GO:0007409 290 0.036
respiratory system development GO:0060541 213 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
proteolysis GO:0006508 192 0.035
response to other organism GO:0051707 293 0.035
intracellular receptor signaling pathway GO:0030522 19 0.034
blastoderm segmentation GO:0007350 159 0.034
multi organism behavior GO:0051705 175 0.034
anterior posterior pattern specification imaginal disc GO:0007448 16 0.033
dna damage checkpoint GO:0000077 78 0.032
egg coat formation GO:0035803 11 0.032
male mating behavior GO:0060179 70 0.032
regulation of dna templated transcription elongation GO:0032784 17 0.031
posttranscriptional gene silencing by rna GO:0035194 45 0.031
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.031
male courtship behavior veined wing generated song production GO:0045433 20 0.031
purine ribonucleotide catabolic process GO:0009154 109 0.031
regulation of programmed cell death GO:0043067 152 0.031
morphogenesis of follicular epithelium GO:0016333 36 0.030
small rna loading onto risc GO:0070922 6 0.030
embryonic pattern specification GO:0009880 174 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
embryonic hemopoiesis GO:0035162 26 0.030
dna packaging GO:0006323 91 0.030
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.030
hematopoietic progenitor cell differentiation GO:0002244 1 0.029
cell death GO:0008219 279 0.029
camera type eye development GO:0043010 4 0.029
cellular response to organic substance GO:0071310 132 0.029
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.028
cellular response to dna damage stimulus GO:0006974 223 0.028
atp dependent chromatin remodeling GO:0043044 22 0.027
male courtship behavior veined wing extension GO:0048065 22 0.027
germ line cyst encapsulation GO:0048138 8 0.026
nuclear division GO:0000280 332 0.026
dna integrity checkpoint GO:0031570 81 0.026
histone methylation GO:0016571 40 0.026
macromolecular complex assembly GO:0065003 256 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
mitochondrion organization GO:0007005 65 0.026
histone exchange GO:0043486 21 0.026
sensory perception GO:0007600 196 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.025
gene silencing by mirna GO:0035195 22 0.025
atp metabolic process GO:0046034 49 0.025
response to ketone GO:1901654 34 0.025
developmental growth GO:0048589 280 0.025
cell aging GO:0007569 2 0.024
regulation of protein localization GO:0032880 76 0.024
histone lysine demethylation GO:0070076 6 0.024
mating GO:0007618 120 0.024
regulation of cell development GO:0060284 215 0.024
endocytosis GO:0006897 310 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.023
posttranscriptional gene silencing GO:0016441 46 0.023
regulation of chromatin organization GO:1902275 32 0.023
hindbrain development GO:0030902 2 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
Mouse
response to organic cyclic compound GO:0014070 89 0.023
histone h4 acetylation GO:0043967 13 0.023
regulation of multi organism process GO:0043900 131 0.023
regulation of organelle organization GO:0033043 196 0.023
regulation of neuron differentiation GO:0045664 103 0.022
negative regulation of defense response GO:0031348 35 0.022
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 130 0.022
negative regulation of chromosome organization GO:2001251 19 0.022
anterior posterior axis specification embryo GO:0008595 103 0.022
protein modification by small protein conjugation GO:0032446 79 0.022
cell proliferation GO:0008283 299 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.022
muscle structure development GO:0061061 224 0.021
spermatogenesis GO:0007283 200 0.021
mrna catabolic process GO:0006402 33 0.021
appendage morphogenesis GO:0035107 397 0.021
neuroblast fate commitment GO:0014017 19 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
histone h2a acetylation GO:0043968 1 0.021
cellular response to reactive oxygen species GO:0034614 14 0.021
cellular ketone metabolic process GO:0042180 24 0.021
neuroblast differentiation GO:0014016 29 0.021
regulation of bmp signaling pathway GO:0030510 23 0.021
germ line stem cell division GO:0042078 25 0.020
protein methylation GO:0006479 43 0.020
regulation of immune system process GO:0002682 176 0.019
mesenchymal cell development GO:0014031 1 0.019
dna conformation change GO:0071103 105 0.019
programmed cell death GO:0012501 257 0.019
bmp signaling pathway GO:0030509 27 0.019
pre mirna processing GO:0031054 3 0.019
cytoplasmic transport GO:0016482 130 0.019
positive regulation of protein modification process GO:0031401 58 0.019
retina development in camera type eye GO:0060041 4 0.019
protein ubiquitination GO:0016567 70 0.018
regulation of molecular function GO:0065009 217 0.018
nucleotide metabolic process GO:0009117 161 0.018
courtship behavior GO:0007619 68 0.018
camera type eye morphogenesis GO:0048593 2 0.018
nucleoside catabolic process GO:0009164 112 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.018
regulation of cell cycle process GO:0010564 181 0.017
embryonic axis specification GO:0000578 107 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.017
peptidyl amino acid modification GO:0018193 105 0.017
negative regulation of histone methylation GO:0031061 3 0.017
regulation of transferase activity GO:0051338 58 0.017
positive regulation of proteolysis GO:0045862 52 0.017
regulation of protein modification process GO:0031399 112 0.017
internal peptidyl lysine acetylation GO:0018393 38 0.017
head development GO:0060322 135 0.017
stem cell differentiation GO:0048863 117 0.017
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.017
mitotic cell cycle embryonic GO:0045448 38 0.017
cell migration GO:0016477 238 0.016
imaginal disc pattern formation GO:0007447 91 0.016
histone h2a ubiquitination GO:0033522 2 0.016
protein localization GO:0008104 284 0.016
reproductive behavior GO:0019098 122 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
segment specification GO:0007379 33 0.016
tripartite regional subdivision GO:0007351 103 0.016
regulation of transcription by chromatin organization GO:0034401 3 0.016
ribonucleoside metabolic process GO:0009119 127 0.015
regulation of sister chromatid cohesion GO:0007063 2 0.015
ribonucleoprotein complex subunit organization GO:0071826 28 0.015
maintenance of protein location GO:0045185 28 0.015
male meiosis GO:0007140 52 0.015
sister chromatid segregation GO:0000819 92 0.015
brain development GO:0007420 120 0.015
regulation of glial cell differentiation GO:0045685 1 0.015
maintenance of location in cell GO:0051651 28 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
multicellular organism growth GO:0035264 46 0.015
regulation of mitotic sister chromatid segregation GO:0033047 28 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
negative regulation of developmental process GO:0051093 201 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
body morphogenesis GO:0010171 2 0.014
nucleoside monophosphate metabolic process GO:0009123 52 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.014
rna interference GO:0016246 27 0.014
negative regulation of organelle organization GO:0010639 56 0.013
male courtship behavior veined wing vibration GO:0016545 21 0.013
regulation of response to alcohol GO:1901419 1 0.013
nucleoside monophosphate catabolic process GO:0009125 39 0.013
positive regulation of mrna processing GO:0050685 4 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
posterior head segmentation GO:0035289 6 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
mitotic nuclear division GO:0007067 213 0.013
death GO:0016265 284 0.013
multi multicellular organism process GO:0044706 123 0.013
protein complex assembly GO:0006461 200 0.013
purine nucleoside monophosphate catabolic process GO:0009128 38 0.013
convergent extension GO:0060026 2 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
regulation of phosphatase activity GO:0010921 3 0.013
regulation of histone h3 k4 methylation GO:0051569 1 0.013
histone h4 k12 acetylation GO:0043983 2 0.013
homeostatic process GO:0042592 199 0.012
spermatid differentiation GO:0048515 114 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
organic substance catabolic process GO:1901575 308 0.012
response to organic substance GO:0010033 284 0.012
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.012
negative regulation of cell fate specification GO:0009996 15 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.012
epidermal cell differentiation GO:0009913 51 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
Mouse
cardioblast cell fate specification GO:0042685 9 0.012
single organism intracellular transport GO:1902582 207 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
limb development GO:0060173 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
response to oxygen containing compound GO:1901700 200 0.012
memory GO:0007613 94 0.012
immune effector process GO:0002252 98 0.011
molting cycle GO:0042303 56 0.011
catabolic process GO:0009056 409 0.011
regulation of sister chromatid segregation GO:0033045 28 0.011
sister chromatid cohesion GO:0007062 18 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
cellular macromolecule localization GO:0070727 220 0.011
maternal specification of dorsal ventral axis oocyte germ line encoded GO:0007311 4 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
amine metabolic process GO:0009308 12 0.011
genitalia development GO:0048806 26 0.011
vitelline membrane formation GO:0030704 11 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
positive regulation of cell communication GO:0010647 250 0.011
negative regulation of histone modification GO:0031057 3 0.011
regulation of cellular response to growth factor stimulus GO:0090287 13 0.011
regulation of protein transport GO:0051223 57 0.010
positive regulation of dna templated transcription elongation GO:0032786 11 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
ecdysone receptor mediated signaling pathway GO:0035076 11 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
regulation of establishment of protein localization GO:0070201 61 0.010
cell cycle dna replication GO:0044786 23 0.010
cytoplasm organization GO:0007028 64 0.010

ash1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org