Drosophila melanogaster

23 known processes

Ilp5 (Dmel_CG33273)

Insulin-like peptide 5

(Aliases: Dilp-5,Dilp5,dILP5,Ilp-5,dILP-5,dilp,dilp5,Dmel\CG33273,ilp5,Dilp,Dilp 5,Ilp,dilp-5,DILP5,DILP,CG33273)

Ilp5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sleep GO:0030431 49 0.990
larval feeding behavior GO:0030536 15 0.956
Fly
single organism behavior GO:0044708 391 0.952
Fly
multi organism behavior GO:0051705 175 0.947
circadian rhythm GO:0007623 105 0.927
Fly
mating behavior GO:0007617 106 0.927
rhythmic behavior GO:0007622 76 0.901
Fly
aging GO:0007568 143 0.837
Fly
determination of adult lifespan GO:0008340 137 0.833
Fly
locomotory behavior GO:0007626 176 0.828
response to insulin GO:0032868 29 0.786
Fly
regulation of behavior GO:0050795 75 0.774
Fly
lipid homeostasis GO:0055088 33 0.752
Fly
female mating behavior GO:0060180 30 0.734
triglyceride homeostasis GO:0070328 18 0.655
Fly
cellular response to peptide hormone stimulus GO:0071375 28 0.601
Fly
regulation of cellular component size GO:0032535 98 0.581
Fly
organ growth GO:0035265 56 0.567
Fly
regulation of cell size GO:0008361 63 0.558
Fly
cellular response to insulin stimulus GO:0032869 28 0.551
Fly
multicellular organismal aging GO:0010259 140 0.543
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.538
Fly
multi multicellular organism process GO:0044706 123 0.523
multi organism reproductive behavior GO:0044705 121 0.502
anatomical structure homeostasis GO:0060249 97 0.492
Fly
regulation of growth GO:0040008 233 0.482
Fly
response to nitrogen compound GO:1901698 90 0.475
Fly
mating GO:0007618 120 0.470
response to organic substance GO:0010033 284 0.464
Fly
insulin receptor signaling pathway GO:0008286 25 0.461
Fly
regulation of cell growth GO:0001558 43 0.457
Fly
response to mercury ion GO:0046689 3 0.438
response to oxygen containing compound GO:1901700 200 0.423
Fly
circadian behavior GO:0048512 76 0.412
Fly
feeding behavior GO:0007631 50 0.412
Fly
regulation of multicellular organism growth GO:0040014 40 0.406
Fly
positive regulation of multicellular organism growth GO:0040018 21 0.398
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.392
Fly
cellular response to peptide GO:1901653 28 0.386
Fly
g protein coupled receptor signaling pathway GO:0007186 136 0.383
positive regulation of developmental process GO:0051094 143 0.378
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.357
Fly
regulation of anatomical structure size GO:0090066 163 0.339
Fly
multicellular organismal reproductive behavior GO:0033057 110 0.338
multicellular organism growth GO:0035264 46 0.337
Fly
reproductive behavior GO:0019098 122 0.335
regulation of developmental growth GO:0048638 174 0.318
Fly
growth GO:0040007 359 0.310
Fly
regulation of organ growth GO:0046620 42 0.306
Fly
cellular response to oxygen containing compound GO:1901701 79 0.283
Fly
larval behavior GO:0030537 42 0.262
Fly
chemical homeostasis GO:0048878 92 0.253
Fly
rhythmic process GO:0048511 106 0.249
Fly
homeostatic process GO:0042592 199 0.234
Fly
small molecule metabolic process GO:0044281 305 0.229
cellular response to endogenous stimulus GO:0071495 80 0.220
Fly
cellular response to chemical stimulus GO:0070887 199 0.218
Fly
hormone metabolic process GO:0042445 33 0.211
developmental growth GO:0048589 280 0.210
Fly
response to endogenous stimulus GO:0009719 119 0.204
Fly
purine ribonucleotide metabolic process GO:0009150 145 0.196
negative regulation of response to stimulus GO:0048585 258 0.187
Fly
insecticide catabolic process GO:0046701 1 0.185
response to organonitrogen compound GO:0010243 75 0.180
Fly
positive regulation of cell growth GO:0030307 19 0.180
Fly
positive regulation of growth GO:0045927 75 0.179
Fly
cell growth GO:0016049 108 0.171
Fly
cellular response to organic substance GO:0071310 132 0.168
Fly
cellular response to nitrogen compound GO:1901699 51 0.162
Fly
acylglycerol homeostasis GO:0055090 19 0.149
Fly
secondary metabolic process GO:0019748 75 0.140
purine nucleotide metabolic process GO:0006163 146 0.134
transmembrane transport GO:0055085 139 0.130
response to hormone GO:0009725 45 0.125
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.111
regulation of feeding behavior GO:0060259 16 0.110
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.106
cellular response to hormone stimulus GO:0032870 44 0.104
Fly
ion transport GO:0006811 145 0.103
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.093
positive regulation of developmental growth GO:0048639 62 0.092
Fly
response to radiation GO:0009314 155 0.088
response to peptide hormone GO:0043434 29 0.087
Fly
cellular response to ethanol GO:0071361 4 0.080
organonitrogen compound metabolic process GO:1901564 318 0.079
response to toxic substance GO:0009636 22 0.079
positive regulation of gene expression GO:0010628 290 0.079
cellular macromolecule localization GO:0070727 220 0.075
intracellular signal transduction GO:0035556 300 0.075
positive regulation of cell proliferation GO:0008284 47 0.072
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.070
nucleotide metabolic process GO:0009117 161 0.069
response to abiotic stimulus GO:0009628 341 0.067
xenobiotic catabolic process GO:0042178 1 0.065
taxis GO:0042330 304 0.065
negative regulation of behavior GO:0048521 8 0.064
Fly
positive regulation of response to stimulus GO:0048584 323 0.063
immune system process GO:0002376 347 0.063
organic hydroxy compound biosynthetic process GO:1901617 21 0.061
positive regulation of cell communication GO:0010647 250 0.061
positive regulation of phosphate metabolic process GO:0045937 139 0.060
cellular lipid metabolic process GO:0044255 83 0.060
lipid metabolic process GO:0006629 121 0.059
organic substance transport GO:0071702 257 0.059
toxin metabolic process GO:0009404 2 0.058
localization of cell GO:0051674 257 0.057
fat soluble vitamin metabolic process GO:0006775 1 0.057
organophosphate metabolic process GO:0019637 195 0.056
regulation of multicellular organismal development GO:2000026 414 0.056
regulation of molecular function GO:0065009 217 0.054
establishment of localization in cell GO:0051649 402 0.054
imaginal disc derived appendage development GO:0048737 399 0.053
adult behavior GO:0030534 137 0.051
regulation of nervous system development GO:0051960 248 0.051
actin cytoskeleton organization GO:0030036 206 0.051
protein localization to organelle GO:0033365 82 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.049
defense response to bacterium GO:0042742 178 0.048
organic hydroxy compound metabolic process GO:1901615 83 0.048
response to alcohol GO:0097305 95 0.048
single organism intracellular transport GO:1902582 207 0.048
oxidation reduction process GO:0055114 123 0.047
response to external biotic stimulus GO:0043207 293 0.047
lipid biosynthetic process GO:0008610 46 0.046
response to organic cyclic compound GO:0014070 89 0.046
nucleobase containing small molecule metabolic process GO:0055086 174 0.046
purine containing compound metabolic process GO:0072521 155 0.046
defense response to other organism GO:0098542 225 0.045
cellular protein localization GO:0034613 160 0.045
fat soluble vitamin biosynthetic process GO:0042362 1 0.045
positive regulation of signal transduction GO:0009967 223 0.045
single organism catabolic process GO:0044712 228 0.044
positive regulation of signaling GO:0023056 243 0.043
compound eye morphogenesis GO:0001745 249 0.043
locomotor rhythm GO:0045475 56 0.043
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.043
response to bacterium GO:0009617 198 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
steroid catabolic process GO:0006706 1 0.042
single organism biosynthetic process GO:0044711 206 0.042
endocytosis GO:0006897 310 0.041
male mating behavior GO:0060179 70 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.039
defense response GO:0006952 300 0.039
cell proliferation GO:0008283 299 0.038
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
organic substance catabolic process GO:1901575 308 0.038
cellular hormone metabolic process GO:0034754 23 0.038
response to ethanol GO:0045471 59 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.037
protein localization GO:0008104 284 0.037
oxoacid metabolic process GO:0043436 103 0.037
lipid catabolic process GO:0016042 21 0.036
cellular response to organonitrogen compound GO:0071417 36 0.036
Fly
intracellular transport GO:0046907 228 0.036
response to insecticide GO:0017085 14 0.035
ribose phosphate metabolic process GO:0019693 145 0.035
organic acid metabolic process GO:0006082 103 0.034
regulation of cell death GO:0010941 173 0.034
positive regulation of phosphorus metabolic process GO:0010562 139 0.034
positive regulation of intracellular signal transduction GO:1902533 116 0.034
courtship behavior GO:0007619 68 0.034
regulation of hormone levels GO:0010817 40 0.034
regulation of circadian sleep wake cycle GO:0042749 25 0.033
neurological system process GO:0050877 358 0.033
nucleocytoplasmic transport GO:0006913 72 0.033
phosphorylation GO:0016310 294 0.033
neuropeptide signaling pathway GO:0007218 45 0.032
vitamin biosynthetic process GO:0009110 1 0.032
regulation of camp metabolic process GO:0030814 12 0.032
epithelial cell differentiation GO:0030855 322 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
catabolic process GO:0009056 409 0.031
response to other organism GO:0051707 293 0.031
cellular ketone metabolic process GO:0042180 24 0.030
cation transport GO:0006812 110 0.030
vesicle mediated transport GO:0016192 381 0.030
embryonic development via the syncytial blastoderm GO:0001700 148 0.030
single organism cellular localization GO:1902580 180 0.030
response to monosaccharide GO:0034284 4 0.030
positive regulation of biosynthetic process GO:0009891 316 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
transcription from rna polymerase ii promoter GO:0006366 368 0.029
response to light stimulus GO:0009416 124 0.029
circadian sleep wake cycle GO:0042745 28 0.029
regulation of response to stress GO:0080134 200 0.028
appendage development GO:0048736 401 0.028
circadian sleep wake cycle process GO:0022410 24 0.028
anion homeostasis GO:0055081 3 0.028
hormone catabolic process GO:0042447 3 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
cellular protein modification process GO:0006464 438 0.028
positive regulation of rna metabolic process GO:0051254 271 0.028
secondary metabolite catabolic process GO:0090487 1 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.027
response to nutrient levels GO:0031667 114 0.026
eye morphogenesis GO:0048592 260 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
carbohydrate derivative biosynthetic process GO:1901137 85 0.026
respiratory system development GO:0060541 213 0.026
response to peptide GO:1901652 29 0.026
Fly
metal ion transport GO:0030001 74 0.026
regulation of membrane potential GO:0042391 35 0.026
response to inorganic substance GO:0010035 44 0.026
cellular homeostasis GO:0019725 80 0.026
negative regulation of cell communication GO:0010648 223 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
axonogenesis GO:0007409 290 0.026
response to biotic stimulus GO:0009607 294 0.026
membrane depolarization GO:0051899 4 0.025
cellular catabolic process GO:0044248 372 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
regulation of neuron differentiation GO:0045664 103 0.024
regulation of intracellular protein transport GO:0033157 46 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
immune response GO:0006955 246 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.024
terpenoid metabolic process GO:0006721 7 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
cell death GO:0008219 279 0.024
regulation of cell differentiation GO:0045595 302 0.024
response to metal ion GO:0010038 23 0.023
protein import GO:0017038 55 0.023
establishment of protein localization GO:0045184 163 0.023
polyol biosynthetic process GO:0046173 3 0.023
response to glucose GO:0009749 2 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
tissue migration GO:0090130 155 0.023
response to organophosphorus GO:0046683 2 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
regulation of neurogenesis GO:0050767 158 0.023
protein import into nucleus GO:0006606 51 0.022
positive regulation of phosphorylation GO:0042327 87 0.022
vitamin metabolic process GO:0006766 2 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
cellular response to radiation GO:0071478 52 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
sterol biosynthetic process GO:0016126 9 0.021
protein localization to nucleus GO:0034504 55 0.021
compound eye development GO:0048749 307 0.021
organelle localization GO:0051640 148 0.021
regulation of catalytic activity GO:0050790 185 0.021
forebrain development GO:0030900 2 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
response to oxidative stress GO:0006979 86 0.020
protein transport GO:0015031 155 0.020
protein modification process GO:0036211 438 0.020
cation transmembrane transport GO:0098655 88 0.020
response to temperature stimulus GO:0009266 106 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
cyclic nucleotide metabolic process GO:0009187 28 0.020
cellular amino acid metabolic process GO:0006520 61 0.019
regulation of protein metabolic process GO:0051246 256 0.019
regulation of cytoplasmic transport GO:1903649 47 0.019
epithelial cell development GO:0002064 274 0.019
stem cell development GO:0048864 79 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
protein targeting to nucleus GO:0044744 51 0.019
regulation of localization GO:0032879 275 0.019
innate immune response GO:0045087 144 0.019
eye development GO:0001654 323 0.018
protein phosphorylation GO:0006468 169 0.018
ion transmembrane transport GO:0034220 122 0.018
establishment of protein localization to organelle GO:0072594 62 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
single organism nuclear import GO:1902593 51 0.018
sensory perception GO:0007600 196 0.018
regulation of cellular localization GO:0060341 136 0.018
phagocytosis GO:0006909 215 0.018
negative regulation of signaling GO:0023057 219 0.017
regulation of growth rate GO:0040009 3 0.017
Fly
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
macromolecular complex assembly GO:0065003 256 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
regulation of apoptotic process GO:0042981 130 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
neuromuscular junction development GO:0007528 149 0.017
cellular amine metabolic process GO:0044106 12 0.017
regulation of programmed cell death GO:0043067 152 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
ras protein signal transduction GO:0007265 88 0.016
purine containing compound biosynthetic process GO:0072522 30 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
positive regulation of cell differentiation GO:0045597 64 0.016
nuclear division GO:0000280 332 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
regionalization GO:0003002 416 0.016
response to heat GO:0009408 63 0.016
negative regulation of transcription regulatory region dna binding GO:2000678 3 0.016
regulation of transport GO:0051049 181 0.016
camera type eye development GO:0043010 4 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
cellular response to hexose stimulus GO:0071331 1 0.015
programmed cell death GO:0012501 257 0.015
hormone biosynthetic process GO:0042446 20 0.015
cellular response to carbohydrate stimulus GO:0071322 4 0.015
nuclear import GO:0051170 51 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
regulation of intracellular transport GO:0032386 64 0.015
response to caffeine GO:0031000 12 0.015
regulation of mapk cascade GO:0043408 92 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
regulation of circadian rhythm GO:0042752 49 0.014
stem cell differentiation GO:0048863 117 0.014
amine metabolic process GO:0009308 12 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
nitrogen compound transport GO:0071705 85 0.014
cgmp metabolic process GO:0046068 11 0.014
male courtship behavior veined wing extension GO:0048065 22 0.014
aggressive behavior GO:0002118 63 0.014
response to extracellular stimulus GO:0009991 116 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
positive regulation of nervous system development GO:0051962 69 0.014
positive regulation of molecular function GO:0044093 136 0.014
regulation of immune system process GO:0002682 176 0.014
negative regulation of signal transduction GO:0009968 206 0.014
intracellular protein transport GO:0006886 104 0.014
chemotaxis GO:0006935 249 0.014
response to hexose GO:0009746 3 0.014
mapk cascade GO:0000165 107 0.014
regulation of transcription regulatory region dna binding GO:2000677 3 0.014
neuron projection guidance GO:0097485 241 0.014
phototaxis GO:0042331 21 0.014
detection of abiotic stimulus GO:0009582 66 0.014
organophosphate biosynthetic process GO:0090407 46 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
toxin catabolic process GO:0009407 1 0.014
positive regulation of cellular component organization GO:0051130 156 0.013
death GO:0016265 284 0.013
axon development GO:0061564 297 0.013
dendrite development GO:0016358 204 0.013
developmental maturation GO:0021700 172 0.013
protein targeting GO:0006605 64 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of cell development GO:0060284 215 0.013
negative regulation of immune system process GO:0002683 50 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
vesicle localization GO:0051648 55 0.013
dendrite morphogenesis GO:0048813 199 0.013
triglyceride catabolic process GO:0019433 3 0.013
regulation of cellular response to stress GO:0080135 89 0.013
adult locomotory behavior GO:0008344 76 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
cellular ion homeostasis GO:0006873 39 0.012
regulation of phosphorylation GO:0042325 147 0.012
alcohol biosynthetic process GO:0046165 14 0.012
response to drug GO:0042493 17 0.012
ecdysteroid metabolic process GO:0045455 19 0.012
positive regulation of catabolic process GO:0009896 105 0.012
alcohol metabolic process GO:0006066 25 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
cytoplasmic transport GO:0016482 130 0.012
cell division GO:0051301 248 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
positive regulation of transport GO:0051050 92 0.012
regulation of catabolic process GO:0009894 170 0.012
synaptic vesicle localization GO:0097479 53 0.011
immune system development GO:0002520 57 0.011
anion transport GO:0006820 41 0.011
endomembrane system organization GO:0010256 119 0.011
nucleoside metabolic process GO:0009116 127 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of protein transport GO:0051223 57 0.011
positive regulation of cell motility GO:2000147 3 0.011
actin filament based process GO:0030029 220 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
regulation of defense response GO:0031347 102 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
organelle fission GO:0048285 340 0.011
fatty acid metabolic process GO:0006631 20 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
regulation of cell projection organization GO:0031344 92 0.011
appendage morphogenesis GO:0035107 397 0.011
regulation of neuron projection development GO:0010975 69 0.011
mesenchymal cell development GO:0014031 1 0.011
rho protein signal transduction GO:0007266 14 0.011
male gamete generation GO:0048232 201 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.011
establishment of organelle localization GO:0051656 122 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.010
wnt signaling pathway GO:0016055 98 0.010
autophagy GO:0006914 108 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
carbohydrate metabolic process GO:0005975 82 0.010
neuron fate commitment GO:0048663 50 0.010
synaptic transmission GO:0007268 288 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
regulation of proteolysis GO:0030162 87 0.010
cellular chemical homeostasis GO:0055082 40 0.010
negative regulation of molecular function GO:0044092 51 0.010
protein complex biogenesis GO:0070271 201 0.010
inorganic cation transmembrane transport GO:0098662 61 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.010
acetate ester metabolic process GO:1900619 2 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
cell type specific apoptotic process GO:0097285 38 0.010
negative regulation of developmental process GO:0051093 201 0.010
kidney development GO:0001822 3 0.010
negative regulation of nervous system development GO:0051961 92 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010

Ilp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
hypertension DOID:10763 0 0.029
artery disease DOID:0050828 0 0.029
vascular disease DOID:178 0 0.029
cardiovascular system disease DOID:1287 0 0.029
essential hypertension DOID:10825 0 0.024
nervous system disease DOID:863 0 0.019