Drosophila melanogaster

29 known processes

mus308 (Dmel_CG6019)

mutagen-sensitive 308

(Aliases: 0443/09,Dmel\CG6019,CG6019,AAF54858,mus-308,Pol theta,Nuc3,Mus308)

mus308 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 26 0.975
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.968
non recombinational repair GO:0000726 7 0.949
cellular response to dna damage stimulus GO:0006974 223 0.930
dna synthesis involved in dna repair GO:0000731 5 0.903
double strand break repair via nonhomologous end joining GO:0006303 5 0.839
dna damage checkpoint GO:0000077 78 0.630
dna repair GO:0006281 54 0.620
translesion synthesis GO:0019985 2 0.606
telomere organization GO:0032200 21 0.590
dna double strand break processing GO:0000729 3 0.559
double strand break repair via homologous recombination GO:0000724 13 0.551
nucleotide excision repair GO:0006289 8 0.545
negative regulation of cell cycle phase transition GO:1901988 103 0.465
chromosome segregation GO:0007059 157 0.414
Fly
mitotic dna damage checkpoint GO:0044773 74 0.399
postreplication repair GO:0006301 2 0.398
dna biosynthetic process GO:0071897 24 0.390
Human
negative regulation of cell cycle process GO:0010948 109 0.369
mitotic cell cycle phase transition GO:0044772 138 0.366
snrna 3 end processing GO:0034472 14 0.322
negative regulation of mitotic cell cycle GO:0045930 109 0.311
dna metabolic process GO:0006259 227 0.302
meiotic chromosome segregation GO:0045132 59 0.287
Fly
chromosome separation GO:0051304 42 0.270
telomere maintenance via recombination GO:0000722 1 0.258
mitotic g2 dna damage checkpoint GO:0007095 69 0.208
mitotic g2 m transition checkpoint GO:0044818 70 0.198
dna geometric change GO:0032392 16 0.195
mitotic dna integrity checkpoint GO:0044774 75 0.193
mitotic cell cycle checkpoint GO:0007093 88 0.188
negative regulation of cell cycle GO:0045786 116 0.174
regulation of cell cycle process GO:0010564 181 0.171
cell cycle phase transition GO:0044770 140 0.155
regulation of cell cycle phase transition GO:1901987 130 0.140
response to abiotic stimulus GO:0009628 341 0.115
cell cycle checkpoint GO:0000075 95 0.114
g2 dna damage checkpoint GO:0031572 69 0.095
meiotic cell cycle process GO:1903046 132 0.091
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.086
response to ionizing radiation GO:0010212 32 0.083
organelle fission GO:0048285 340 0.081
Fly
purine nucleoside catabolic process GO:0006152 112 0.072
Human
nuclear division GO:0000280 332 0.071
Fly
regulation of dna repair GO:0006282 5 0.071
regulation of mitotic cell cycle phase transition GO:1901990 130 0.070
recombinational repair GO:0000725 13 0.065
organic substance catabolic process GO:1901575 308 0.064
Human
meiotic chromosome separation GO:0051307 8 0.063
telomere maintenance GO:0000723 21 0.061
regulation of response to dna damage stimulus GO:2001020 23 0.061
dna integrity checkpoint GO:0031570 81 0.058
regulation of mitotic cell cycle GO:0007346 190 0.056
purine ribonucleoside metabolic process GO:0046128 127 0.056
Human
purine ribonucleotide catabolic process GO:0009154 109 0.054
Human
ribonucleotide metabolic process GO:0009259 145 0.052
Human
aging GO:0007568 143 0.051
glycosyl compound catabolic process GO:1901658 112 0.049
Human
negative regulation of cellular metabolic process GO:0031324 382 0.048
response to radiation GO:0009314 155 0.046
meiotic cell cycle GO:0051321 171 0.045
Fly
chromosome organization GO:0051276 360 0.045
Fly
organophosphate catabolic process GO:0046434 112 0.044
Human
meiosis i GO:0007127 59 0.044
intracellular signal transduction GO:0035556 300 0.043
compound eye photoreceptor cell differentiation GO:0001751 140 0.043
reciprocal meiotic recombination GO:0007131 19 0.043
regulation of double strand break repair GO:2000779 3 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
regulation of cell cycle GO:0051726 291 0.041
ribonucleoside catabolic process GO:0042454 112 0.041
Human
mitotic sister chromatid separation GO:0051306 30 0.040
regulation of developmental growth GO:0048638 174 0.040
atp metabolic process GO:0046034 49 0.039
Human
catabolic process GO:0009056 409 0.039
Human
modification dependent macromolecule catabolic process GO:0043632 79 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
single organism biosynthetic process GO:0044711 206 0.038
response to alkaloid GO:0043279 26 0.038
response to uv GO:0009411 24 0.037
purine nucleotide catabolic process GO:0006195 109 0.037
Human
dna recombination GO:0006310 32 0.037
positive regulation of transcription dna templated GO:0045893 266 0.036
cellular catabolic process GO:0044248 372 0.036
Human
mitotic dna replication checkpoint GO:0033314 5 0.036
nucleoside phosphate metabolic process GO:0006753 162 0.036
Human
organonitrogen compound metabolic process GO:1901564 318 0.035
Human
regulation of nervous system development GO:0051960 248 0.035
regulation of phosphorylation GO:0042325 147 0.035
purine ribonucleoside catabolic process GO:0046130 112 0.035
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.034
multicellular organismal aging GO:0010259 140 0.034
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.033
Human
signal transduction in response to dna damage GO:0042770 3 0.032
wing disc morphogenesis GO:0007472 344 0.032
dna amplification GO:0006277 11 0.032
embryo development ending in birth or egg hatching GO:0009792 152 0.031
snrna processing GO:0016180 14 0.031
purine containing compound catabolic process GO:0072523 112 0.031
Human
small molecule metabolic process GO:0044281 305 0.031
Human
nucleotide metabolic process GO:0009117 161 0.030
Human
dna conformation change GO:0071103 105 0.030
proteasomal protein catabolic process GO:0010498 59 0.030
regulation of cellular response to stress GO:0080135 89 0.029
negative regulation of response to stimulus GO:0048585 258 0.028
regulation of actin filament polymerization GO:0030833 25 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
Human
regulation of catabolic process GO:0009894 170 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
Human
cell proliferation GO:0008283 299 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
Human
cell aging GO:0007569 2 0.026
neurological system process GO:0050877 358 0.026
protein catabolic process GO:0030163 101 0.026
anatomical structure homeostasis GO:0060249 97 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
Human
cellular response to ionizing radiation GO:0071479 15 0.025
amine metabolic process GO:0009308 12 0.025
purine ribonucleotide metabolic process GO:0009150 145 0.025
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.025
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
regulation of dna metabolic process GO:0051052 34 0.024
reciprocal dna recombination GO:0035825 19 0.024
regulation of neurogenesis GO:0050767 158 0.024
cuticle development GO:0042335 86 0.024
antimicrobial humoral response GO:0019730 99 0.024
post embryonic hemopoiesis GO:0035166 17 0.024
germarium derived oocyte fate determination GO:0007294 26 0.023
Fly
nucleoside triphosphate catabolic process GO:0009143 108 0.023
Human
cell cycle dna replication GO:0044786 23 0.023
regulation of dna recombination GO:0000018 4 0.023
nucleoside metabolic process GO:0009116 127 0.023
Human
regulation of multicellular organismal development GO:2000026 414 0.023
regulation of cell morphogenesis GO:0022604 163 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.022
Human
resolution of meiotic recombination intermediates GO:0000712 6 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
Human
body morphogenesis GO:0010171 2 0.021
actin filament polymerization GO:0030041 27 0.021
negative regulation of catabolic process GO:0009895 36 0.021
negative regulation of cell division GO:0051782 17 0.021
macromolecule catabolic process GO:0009057 161 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.021
protein complex biogenesis GO:0070271 201 0.021
actin filament based process GO:0030029 220 0.021
growth GO:0040007 359 0.020
multi multicellular organism process GO:0044706 123 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
single organism intracellular transport GO:1902582 207 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
Human
regulation of organelle organization GO:0033043 196 0.020
multicellular organism growth GO:0035264 46 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.019
immune response GO:0006955 246 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
Human
purine nucleoside monophosphate catabolic process GO:0009128 38 0.019
Human
ribonucleoside monophosphate catabolic process GO:0009158 39 0.019
Human
neuropeptide signaling pathway GO:0007218 45 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
proteolysis GO:0006508 192 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
cellular amine metabolic process GO:0044106 12 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
cell division GO:0051301 248 0.018
regulation of cell division GO:0051302 72 0.017
rna processing GO:0006396 147 0.017
cellular protein catabolic process GO:0044257 83 0.017
determination of adult lifespan GO:0008340 137 0.017
regulation of chromosome organization GO:0033044 64 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
humoral immune response GO:0006959 117 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
Human
developmental growth GO:0048589 280 0.016
regulation of cell shape GO:0008360 113 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
Human
response to x ray GO:0010165 8 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
response to oxygen containing compound GO:1901700 200 0.016
nucleotide catabolic process GO:0009166 109 0.016
Human
organophosphate metabolic process GO:0019637 195 0.016
Human
oocyte fate determination GO:0030716 27 0.016
Fly
replication fork processing GO:0031297 0 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
Human
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
negative regulation of sister chromatid segregation GO:0033046 13 0.016
chromatin remodeling GO:0006338 72 0.016
multi organism behavior GO:0051705 175 0.016
regionalization GO:0003002 416 0.016
Fly
regulation of nuclear division GO:0051783 58 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.015
regulation of neuron differentiation GO:0045664 103 0.015
chromatin organization GO:0006325 207 0.015
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.015
negative regulation of meiotic cell cycle GO:0051447 2 0.015
endocytosis GO:0006897 310 0.015
purine containing compound metabolic process GO:0072521 155 0.015
Human
carboxylic acid metabolic process GO:0019752 92 0.015
negative regulation of signal transduction GO:0009968 206 0.015
centrosome cycle GO:0007098 137 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
defense response to other organism GO:0098542 225 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
Human
response to alcohol GO:0097305 95 0.014
peptidyl lysine acetylation GO:0018394 39 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
rna 3 end processing GO:0031123 45 0.014
gtp catabolic process GO:0006184 72 0.014
regulation of rna splicing GO:0043484 69 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
snrna metabolic process GO:0016073 14 0.014
cilium organization GO:0044782 41 0.014
response to light stimulus GO:0009416 124 0.014
regulation of catalytic activity GO:0050790 185 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
Human
actin cytoskeleton organization GO:0030036 206 0.013
reproductive behavior GO:0019098 122 0.013
meiotic nuclear division GO:0007126 151 0.013
Fly
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
Human
nucleoside catabolic process GO:0009164 112 0.013
Human
protein modification process GO:0036211 438 0.013
production of molecular mediator of immune response GO:0002440 46 0.013
response to other organism GO:0051707 293 0.013
sex differentiation GO:0007548 81 0.013
nucleoside monophosphate catabolic process GO:0009125 39 0.013
Human
modification dependent protein catabolic process GO:0019941 78 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
Human
actin polymerization or depolymerization GO:0008154 31 0.013
anterior posterior pattern specification GO:0009952 136 0.013
Fly
cell death GO:0008219 279 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
reproductive structure development GO:0048608 74 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
Human
response to oxidative stress GO:0006979 86 0.013
vesicle mediated transport GO:0016192 381 0.013
atp dependent chromatin remodeling GO:0043044 22 0.012
intracellular mrna localization GO:0008298 66 0.012
Fly
negative regulation of cell communication GO:0010648 223 0.012
death GO:0016265 284 0.012
connective tissue development GO:0061448 3 0.012
response to organic substance GO:0010033 284 0.012
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.012
chitin based cuticle development GO:0040003 49 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
immune effector process GO:0002252 98 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
dopamine biosynthetic process GO:0042416 3 0.012
single organism catabolic process GO:0044712 228 0.012
Human
mitotic nuclear division GO:0007067 213 0.012
defense response GO:0006952 300 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
response to camptothecin GO:1901563 2 0.012
immune system process GO:0002376 347 0.012
response to external biotic stimulus GO:0043207 293 0.011
cellular protein complex assembly GO:0043623 71 0.011
multi organism reproductive behavior GO:0044705 121 0.011
dna methylation or demethylation GO:0044728 4 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
axonogenesis GO:0007409 290 0.011
positive regulation of nervous system development GO:0051962 69 0.011
regulation of mitotic sister chromatid segregation GO:0033047 28 0.011
regulation of proteolysis GO:0030162 87 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
molting cycle process GO:0022404 29 0.011
regulation of protein catabolic process GO:0042176 55 0.011
regulation of mitosis GO:0007088 56 0.011
regulation of molecular function GO:0065009 217 0.011
dna packaging GO:0006323 91 0.011
regulation of sister chromatid segregation GO:0033045 28 0.010
macromolecular complex assembly GO:0065003 256 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
neuroblast proliferation GO:0007405 74 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
positive regulation of signaling GO:0023056 243 0.010
regulation of protein metabolic process GO:0051246 256 0.010
morphogenesis of a branching epithelium GO:0061138 45 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
gtp metabolic process GO:0046039 72 0.010
chorion containing eggshell formation GO:0007304 105 0.010
aromatic compound catabolic process GO:0019439 166 0.010
Human
regulation of phosphorus metabolic process GO:0051174 210 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010

mus308 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.047
cancer DOID:162 0 0.047
organ system cancer DOID:0050686 0 0.040
thoracic cancer DOID:5093 0 0.040
disease of anatomical entity DOID:7 0 0.012