Drosophila melanogaster

87 known processes

pcs (Dmel_CG7761)

parcas

(Aliases: prt,CG7761,Dmel\CG7761)

pcs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.594
response to radiation GO:0009314 155 0.410
post embryonic appendage morphogenesis GO:0035120 385 0.358
negative regulation of response to stimulus GO:0048585 258 0.355
rna localization GO:0006403 115 0.316
regulation of multicellular organismal development GO:2000026 414 0.295
appendage morphogenesis GO:0035107 397 0.280
myotube differentiation GO:0014902 46 0.257
establishment of localization in cell GO:0051649 402 0.244
establishment of nucleus localization GO:0040023 26 0.224
response to light stimulus GO:0009416 124 0.206
negative regulation of cell communication GO:0010648 223 0.198
pole plasm rna localization GO:0007316 52 0.185
germ cell migration GO:0008354 43 0.175
regulation of pole plasm oskar mrna localization GO:0007317 27 0.170
cell migration GO:0016477 238 0.169
regulation of cell cycle GO:0051726 291 0.155
kidney epithelium development GO:0072073 3 0.151
regulation of cell differentiation GO:0045595 302 0.147
negative regulation of cellular metabolic process GO:0031324 382 0.143
imaginal disc derived appendage development GO:0048737 399 0.135
muscle cell differentiation GO:0042692 103 0.126
imaginal disc derived wing morphogenesis GO:0007476 337 0.121
proteolysis GO:0006508 192 0.120
cell motility GO:0048870 251 0.117
appendage development GO:0048736 401 0.113
phosphorylation GO:0016310 294 0.113
nephron epithelium development GO:0072009 3 0.110
positive regulation of cellular component organization GO:0051130 156 0.107
pole plasm assembly GO:0007315 61 0.107
regulation of defense response GO:0031347 102 0.098
wing disc morphogenesis GO:0007472 344 0.088
blastoderm segmentation GO:0007350 159 0.087
oocyte differentiation GO:0009994 145 0.085
regulation of epithelial cell proliferation GO:0050678 4 0.084
regulation of nervous system development GO:0051960 248 0.083
ubiquitin dependent protein catabolic process GO:0006511 78 0.081
regulation of cellular amino acid metabolic process GO:0006521 0 0.077
cell maturation GO:0048469 144 0.075
regulation of phosphorylation GO:0042325 147 0.074
axis specification GO:0009798 167 0.074
mesoderm development GO:0007498 78 0.073
regulation of localization GO:0032879 275 0.070
regulation of embryonic pattern specification GO:1902875 27 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.067
pole plasm mrna localization GO:0019094 49 0.067
negative regulation of signaling GO:0023057 219 0.066
myoblast fusion GO:0007520 43 0.066
embryonic pattern specification GO:0009880 174 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.064
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.061
kidney development GO:0001822 3 0.060
regulation of cellular component biogenesis GO:0044087 201 0.057
positive regulation of phosphate metabolic process GO:0045937 139 0.057
synaptic growth at neuromuscular junction GO:0051124 119 0.057
nephron development GO:0072006 3 0.055
regulation of transport GO:0051049 181 0.054
cellular macromolecular complex assembly GO:0034622 153 0.054
organelle localization GO:0051640 148 0.051
regulation of mitotic cell cycle phase transition GO:1901990 130 0.051
localization of cell GO:0051674 257 0.049
regulation of actin filament length GO:0030832 27 0.047
pole plasm oskar mrna localization GO:0045451 46 0.047
negative regulation of intracellular signal transduction GO:1902532 57 0.047
negative regulation of phosphorylation GO:0042326 35 0.046
regulation of actin polymerization or depolymerization GO:0008064 27 0.046
oocyte axis specification GO:0007309 108 0.045
epidermis development GO:0008544 65 0.045
cellular amino acid metabolic process GO:0006520 61 0.044
oocyte development GO:0048599 124 0.043
gliogenesis GO:0042063 80 0.043
regulation of cellular amine metabolic process GO:0033238 3 0.042
protein catabolic process GO:0030163 101 0.042
regulation of cell cycle phase transition GO:1901987 130 0.042
cellular protein modification process GO:0006464 438 0.042
g protein coupled receptor signaling pathway GO:0007186 136 0.041
cell death GO:0008219 279 0.041
Worm
dephosphorylation GO:0016311 51 0.040
embryonic development via the syncytial blastoderm GO:0001700 148 0.040
cell junction assembly GO:0034329 42 0.039
anterior posterior axis specification embryo GO:0008595 103 0.039
cellular catabolic process GO:0044248 372 0.037
regulation of erbb signaling pathway GO:1901184 42 0.037
skin development GO:0043588 65 0.036
intracellular transport GO:0046907 228 0.036
negative regulation of erbb signaling pathway GO:1901185 29 0.036
cognition GO:0050890 141 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
regulation of actin cytoskeleton organization GO:0032956 42 0.035
intracellular signal transduction GO:0035556 300 0.034
Human
positive regulation of nucleoside metabolic process GO:0045979 47 0.034
response to external biotic stimulus GO:0043207 293 0.033
organelle assembly GO:0070925 198 0.033
regulation of wnt signaling pathway GO:0030111 68 0.032
connective tissue development GO:0061448 3 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
epithelial cell differentiation GO:0030855 322 0.032
regulation of phosphate metabolic process GO:0019220 210 0.031
nephron epithelium morphogenesis GO:0072088 3 0.031
cytoplasm organization GO:0007028 64 0.030
anterior posterior axis specification GO:0009948 109 0.030
regulation of oocyte development GO:0060281 27 0.029
negative regulation of signal transduction GO:0009968 206 0.029
regulation of molecular function GO:0065009 217 0.029
negative regulation of phosphate metabolic process GO:0045936 45 0.029
regulation of growth GO:0040008 233 0.028
dendrite development GO:0016358 204 0.028
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.028
maternal determination of anterior posterior axis embryo GO:0008358 74 0.028
neurological system process GO:0050877 358 0.028
programmed cell death GO:0012501 257 0.028
Worm
regulation of nuclear division GO:0051783 58 0.028
response to wounding GO:0009611 94 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.027
establishment of organelle localization GO:0051656 122 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
response to abiotic stimulus GO:0009628 341 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
intracellular mrna localization GO:0008298 66 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
positive regulation of cellular component biogenesis GO:0044089 80 0.026
secretion GO:0046903 109 0.026
regulation of cell cycle process GO:0010564 181 0.025
regulation of cellular localization GO:0060341 136 0.025
regulation of embryonic development GO:0045995 68 0.025
taxis GO:0042330 304 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
cellular response to radiation GO:0071478 52 0.024
embryonic axis specification GO:0000578 107 0.023
cellular protein complex assembly GO:0043623 71 0.023
nuclear migration GO:0007097 20 0.023
lipid localization GO:0010876 54 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
regulation of cell division GO:0051302 72 0.022
cellular response to light stimulus GO:0071482 37 0.022
regulation of multi organism process GO:0043900 131 0.022
regulation of proteolysis GO:0030162 87 0.022
pole plasm protein localization GO:0007318 10 0.022
macromolecular complex assembly GO:0065003 256 0.022
negative regulation of nervous system development GO:0051961 92 0.022
developmental maturation GO:0021700 172 0.022
ovarian follicle cell development GO:0030707 248 0.022
regulation of response to stress GO:0080134 200 0.021
regulation of hydrolase activity GO:0051336 97 0.021
cell cycle phase transition GO:0044770 140 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
organic substance catabolic process GO:1901575 308 0.021
response to monosaccharide GO:0034284 4 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
oocyte construction GO:0007308 112 0.020
response to organic substance GO:0010033 284 0.020
camera type eye morphogenesis GO:0048593 2 0.020
positive regulation of nervous system development GO:0051962 69 0.020
nucleus localization GO:0051647 34 0.020
regulation of membrane potential GO:0042391 35 0.020
regulation of organelle organization GO:0033043 196 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.020
positive regulation of molecular function GO:0044093 136 0.019
tripartite regional subdivision GO:0007351 103 0.019
catabolic process GO:0009056 409 0.019
positive regulation of cell development GO:0010720 61 0.019
autophagic cell death GO:0048102 83 0.019
regulation of neurogenesis GO:0050767 158 0.018
muscle structure development GO:0061061 224 0.018
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.018
peptidyl tyrosine phosphorylation GO:0018108 24 0.017
endocytosis GO:0006897 310 0.017
response to hexose GO:0009746 3 0.017
camera type eye development GO:0043010 4 0.017
regulation of anatomical structure size GO:0090066 163 0.017
organic acid metabolic process GO:0006082 103 0.017
detection of stimulus GO:0051606 156 0.017
protein polymerization GO:0051258 42 0.017
cellular response to hexose stimulus GO:0071331 1 0.017
positive regulation of cell communication GO:0010647 250 0.017
protein modification process GO:0036211 438 0.016
pole cell development GO:0007277 26 0.016
central nervous system development GO:0007417 201 0.016
developmental induction GO:0031128 3 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
regulation of cell development GO:0060284 215 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
substrate dependent cell migration GO:0006929 3 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
positive regulation of cell cycle process GO:0090068 28 0.016
cell growth GO:0016049 108 0.016
cellularization GO:0007349 90 0.016
positive regulation of cell differentiation GO:0045597 64 0.015
salivary gland histolysis GO:0035070 88 0.015
negative regulation of gene expression GO:0010629 387 0.015
learning or memory GO:0007611 141 0.015
negative regulation of phosphorus metabolic process GO:0010563 45 0.015
sarcomere organization GO:0045214 26 0.015
regulation of glial cell differentiation GO:0045685 1 0.015
gland morphogenesis GO:0022612 145 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.014
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.014
single organism intracellular transport GO:1902582 207 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
cytoplasmic transport GO:0016482 130 0.014
regulation of epithelial cell differentiation GO:0030856 4 0.014
negative regulation of kinase activity GO:0033673 16 0.014
regulation of catalytic activity GO:0050790 185 0.014
mapk cascade GO:0000165 107 0.014
single organism biosynthetic process GO:0044711 206 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
tissue death GO:0016271 102 0.014
telencephalon development GO:0021537 2 0.014
regulation of innate immune response GO:0045088 71 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
regulation of protein metabolic process GO:0051246 256 0.013
developmental programmed cell death GO:0010623 138 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
detection of abiotic stimulus GO:0009582 66 0.013
lipid metabolic process GO:0006629 121 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.013
regulation of nucleocytoplasmic transport GO:0046822 35 0.013
positive regulation of gene expression GO:0010628 290 0.013
r7 cell differentiation GO:0045466 43 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
negative regulation of defense response GO:0031348 35 0.013
regulation of mapk cascade GO:0043408 92 0.013
adult behavior GO:0030534 137 0.013
endodermal cell fate commitment GO:0001711 3 0.013
developmental pigmentation GO:0048066 68 0.013
response to ketone GO:1901654 34 0.013
single organism behavior GO:0044708 391 0.013
compound eye development GO:0048749 307 0.012
response to lipopolysaccharide GO:0032496 4 0.012
nephron tubule morphogenesis GO:0072078 3 0.012
regulation of actin filament based process GO:0032970 42 0.012
stem cell fate commitment GO:0048865 25 0.012
regulation of actin filament polymerization GO:0030833 25 0.012
regulation of meiosis GO:0040020 3 0.012
anterior posterior pattern specification GO:0009952 136 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.012
wound healing GO:0042060 75 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
cellular ketone metabolic process GO:0042180 24 0.012
signal release GO:0023061 49 0.012
positive regulation of atp catabolic process GO:1903291 3 0.012
stress activated mapk cascade GO:0051403 52 0.012
defense response GO:0006952 300 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
urogenital system development GO:0001655 72 0.011
imaginal disc pattern formation GO:0007447 91 0.011
regulation of immune system process GO:0002682 176 0.011
dorsal closure GO:0007391 79 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
cell fate specification GO:0001708 71 0.011
negative regulation of cell cycle GO:0045786 116 0.011
chaeta development GO:0022416 97 0.011
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.011
response to organophosphorus GO:0046683 2 0.011
multicellular organismal signaling GO:0035637 12 0.011
small molecule metabolic process GO:0044281 305 0.011
transmembrane transport GO:0055085 139 0.011
organic substance transport GO:0071702 257 0.011
body morphogenesis GO:0010171 2 0.010
myotube cell development GO:0014904 3 0.010
positive regulation of signaling GO:0023056 243 0.010
ion transmembrane transport GO:0034220 122 0.010
cell cell junction organization GO:0045216 55 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
spermatid differentiation GO:0048515 114 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
segmentation GO:0035282 207 0.010
positive regulation of developmental process GO:0051094 143 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010
memory GO:0007613 94 0.010
nuclear transport GO:0051169 72 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
action potential GO:0001508 13 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
positive regulation of neurogenesis GO:0050769 41 0.010

pcs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.013
disease of anatomical entity DOID:7 0 0.013
eye and adnexa disease DOID:1492 0 0.013
nervous system disease DOID:863 0 0.013