Drosophila melanogaster

28 known processes

Rpn1 (Dmel_CG7762)

CG7762 gene product from transcript CG7762-RA

(Aliases: BcDNA:LD21723,Dmel\CG7762,CG7762,p97)

Rpn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 79 0.931
proteolysis GO:0006508 192 0.774
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.530
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.504
proteasome assembly GO:0043248 2 0.494
ubiquitin dependent protein catabolic process GO:0006511 78 0.471
modification dependent protein catabolic process GO:0019941 78 0.463
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.453
dna repair GO:0006281 54 0.373
cellular catabolic process GO:0044248 372 0.339
catabolic process GO:0009056 409 0.337
proteasomal protein catabolic process GO:0010498 59 0.311
protein catabolic process GO:0030163 101 0.284
embryo development ending in birth or egg hatching GO:0009792 152 0.259
Worm
cellular macromolecule catabolic process GO:0044265 136 0.238
determination of adult lifespan GO:0008340 137 0.216
Worm
cellular protein catabolic process GO:0044257 83 0.212
protein complex assembly GO:0006461 200 0.194
protein complex biogenesis GO:0070271 201 0.192
aging GO:0007568 143 0.191
Worm
organic substance catabolic process GO:1901575 308 0.174
mitotic spindle organization GO:0007052 220 0.156
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.150
mitotic nuclear division GO:0007067 213 0.147
regulation of localization GO:0032879 275 0.142
spindle assembly GO:0051225 80 0.140
positive regulation of proteolysis GO:0045862 52 0.136
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.130
macromolecule catabolic process GO:0009057 161 0.127
organelle assembly GO:0070925 198 0.125
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.116
cellular protein complex assembly GO:0043623 71 0.116
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.109
transcription from rna polymerase ii promoter GO:0006366 368 0.107
macromolecular complex assembly GO:0065003 256 0.104
spindle elongation GO:0051231 83 0.103
cellular response to dna damage stimulus GO:0006974 223 0.100
multicellular organismal aging GO:0010259 140 0.093
Worm
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.091
regulation of organelle organization GO:0033043 196 0.088
dna templated transcription elongation GO:0006354 18 0.086
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.081
regulation of cellular component biogenesis GO:0044087 201 0.080
regulation of cellular protein metabolic process GO:0032268 243 0.079
positive regulation of peptidase activity GO:0010952 29 0.069
organelle fission GO:0048285 340 0.068
death GO:0016265 284 0.066
Worm
eye development GO:0001654 323 0.065
dendrite development GO:0016358 204 0.058
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.058
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.055
regulation of proteolysis GO:0030162 87 0.055
nuclear division GO:0000280 332 0.054
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.054
ribonucleotide metabolic process GO:0009259 145 0.052
regulation of proteasomal protein catabolic process GO:0061136 39 0.052
cellular macromolecular complex assembly GO:0034622 153 0.052
lateral inhibition GO:0046331 206 0.051
cell death GO:0008219 279 0.050
Worm
positive regulation of biosynthetic process GO:0009891 316 0.049
double strand break repair GO:0006302 26 0.049
nucleobase containing small molecule metabolic process GO:0055086 174 0.048
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.047
spindle assembly involved in mitosis GO:0090307 50 0.047
positive regulation of macromolecule metabolic process GO:0010604 405 0.047
regulation of immune system process GO:0002682 176 0.046
compound eye morphogenesis GO:0001745 249 0.044
response to organic substance GO:0010033 284 0.044
purine ribonucleotide metabolic process GO:0009150 145 0.043
positive regulation of cellular component organization GO:0051130 156 0.043
response to biotic stimulus GO:0009607 294 0.043
organonitrogen compound metabolic process GO:1901564 318 0.042
cytoplasmic transport GO:0016482 130 0.042
positive regulation of cellular catabolic process GO:0031331 95 0.042
tissue homeostasis GO:0001894 36 0.042
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.041
nucleoside catabolic process GO:0009164 112 0.041
larval development GO:0002164 104 0.041
Worm
ribonucleoside metabolic process GO:0009119 127 0.040
positive regulation of endopeptidase activity GO:0010950 26 0.040
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.039
embryonic morphogenesis GO:0048598 206 0.039
purine nucleoside catabolic process GO:0006152 112 0.038
body morphogenesis GO:0010171 2 0.037
dna templated transcription initiation GO:0006352 25 0.037
negative regulation of gene expression GO:0010629 387 0.037
purine ribonucleoside metabolic process GO:0046128 127 0.036
organophosphate metabolic process GO:0019637 195 0.036
response to other organism GO:0051707 293 0.036
purine containing compound metabolic process GO:0072521 155 0.035
immune response GO:0006955 246 0.034
mitotic spindle elongation GO:0000022 81 0.033
regulation of catabolic process GO:0009894 170 0.033
tube development GO:0035295 244 0.032
protein dna complex subunit organization GO:0071824 86 0.032
positive regulation of protein complex assembly GO:0031334 22 0.031
positive regulation of gene expression GO:0010628 290 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
purine ribonucleoside catabolic process GO:0046130 112 0.030
ubiquitin homeostasis GO:0010992 1 0.030
immune system process GO:0002376 347 0.030
aromatic compound catabolic process GO:0019439 166 0.029
response to external biotic stimulus GO:0043207 293 0.029
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
secretion GO:0046903 109 0.027
positive regulation of rna metabolic process GO:0051254 271 0.027
defense response GO:0006952 300 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
mapk cascade GO:0000165 107 0.027
defense response to gram negative bacterium GO:0050829 94 0.027
spindle organization GO:0007051 253 0.026
ribose phosphate metabolic process GO:0019693 145 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
nucleoside metabolic process GO:0009116 127 0.025
positive regulation of molecular function GO:0044093 136 0.025
multicellular organismal homeostasis GO:0048871 41 0.024
positive regulation of immune system process GO:0002684 68 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
compound eye photoreceptor cell differentiation GO:0001751 140 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
regulation of vesicle mediated transport GO:0060627 59 0.023
centrosome organization GO:0051297 163 0.023
regulation of endopeptidase activity GO:0052548 36 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
protein localization GO:0008104 284 0.021
cell proliferation GO:0008283 299 0.021
nucleotide catabolic process GO:0009166 109 0.021
carboxylic acid metabolic process GO:0019752 92 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
positive regulation of lipid storage GO:0010884 4 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
single organism behavior GO:0044708 391 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.019
regulation of transport GO:0051049 181 0.018
autophagy GO:0006914 108 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
organophosphate catabolic process GO:0046434 112 0.018
regulation of innate immune response GO:0045088 71 0.018
protein dna complex assembly GO:0065004 63 0.018
homeostatic process GO:0042592 199 0.017
eye morphogenesis GO:0048592 260 0.017
regulation of immune effector process GO:0002697 52 0.017
epithelial tube morphogenesis GO:0060562 88 0.017
heterocycle catabolic process GO:0046700 166 0.017
positive regulation of catabolic process GO:0009896 105 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
appendage development GO:0048736 401 0.017
phagocytosis GO:0006909 215 0.017
protein ubiquitination GO:0016567 70 0.017
purine nucleoside monophosphate metabolic process GO:0009126 50 0.017
small molecule metabolic process GO:0044281 305 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
programmed cell death GO:0012501 257 0.017
Worm
innate immune response GO:0045087 144 0.017
regulation of protein catabolic process GO:0042176 55 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
regulation of endocytosis GO:0030100 37 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
single organism catabolic process GO:0044712 228 0.016
purine nucleoside monophosphate catabolic process GO:0009128 38 0.016
protein heterooligomerization GO:0051291 4 0.016
nucleotide metabolic process GO:0009117 161 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.015
regulation of response to biotic stimulus GO:0002831 63 0.015
regulation of cell differentiation GO:0045595 302 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
n glycan processing GO:0006491 3 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
positive regulation of protein catabolic process GO:0045732 34 0.015
regulation of immune response GO:0050776 118 0.015
establishment of protein localization GO:0045184 163 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
regulation of cell cycle process GO:0010564 181 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
defense response to bacterium GO:0042742 178 0.014
kidney development GO:0001822 3 0.014
single organism intracellular transport GO:1902582 207 0.014
nucleotide excision repair GO:0006289 8 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
digestive tract development GO:0048565 149 0.014
regulation of defense response GO:0031347 102 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
protein processing GO:0016485 68 0.014
apoptotic process GO:0006915 159 0.013
Worm
regulation of peptidase activity GO:0052547 39 0.013
vesicle mediated transport GO:0016192 381 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
atp catabolic process GO:0006200 38 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
endocytosis GO:0006897 310 0.013
single organism cellular localization GO:1902580 180 0.013
regulation of molecular function GO:0065009 217 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
peptide metabolic process GO:0006518 80 0.013
humoral immune response GO:0006959 117 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
rna localization GO:0006403 115 0.013
double strand break repair via homologous recombination GO:0000724 13 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
camera type eye development GO:0043010 4 0.012
eye photoreceptor cell development GO:0042462 81 0.012
skeletal muscle fiber development GO:0048741 3 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
macroautophagy GO:0016236 42 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
organic substance transport GO:0071702 257 0.012
exocrine system development GO:0035272 162 0.012
regulation of cell cycle GO:0051726 291 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
dna metabolic process GO:0006259 227 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
appendage morphogenesis GO:0035107 397 0.011
intracellular transport GO:0046907 228 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
tissue morphogenesis GO:0048729 297 0.011
developmental growth GO:0048589 280 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
chemotaxis GO:0006935 249 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
atp metabolic process GO:0046034 49 0.010
regionalization GO:0003002 416 0.010
positive regulation of innate immune response GO:0045089 38 0.010
cell fate commitment involved in pattern specification GO:0060581 31 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
positive regulation of developmental process GO:0051094 143 0.010
nf kappab import into nucleus GO:0042348 1 0.010
lipid localization GO:0010876 54 0.010

Rpn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020