Drosophila melanogaster

37 known processes

tko (Dmel_CG7925)

technical knockout

(Aliases: rps12,EG:BACH59J11.1,mt-rps12,S12,MRP-S12,Dmel\CG7925,l(1)tko,l(1)3Ab,MRPS12,CG7925,mRpS12)

tko biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.898
reproductive behavior GO:0019098 122 0.681
multi organism behavior GO:0051705 175 0.676
multi organism reproductive behavior GO:0044705 121 0.569
multicellular organismal reproductive behavior GO:0033057 110 0.321
multi multicellular organism process GO:0044706 123 0.278
localization of cell GO:0051674 257 0.138
neurological system process GO:0050877 358 0.129
vesicle mediated transport GO:0016192 381 0.114
atp biosynthetic process GO:0006754 2 0.103
response to heat GO:0009408 63 0.094
spermatid development GO:0007286 98 0.086
neuron projection guidance GO:0097485 241 0.080
cellular component assembly involved in morphogenesis GO:0010927 151 0.080
actin filament based process GO:0030029 220 0.076
response to oxidative stress GO:0006979 86 0.073
response to abiotic stimulus GO:0009628 341 0.070
taxis GO:0042330 304 0.069
regulation of multicellular organism growth GO:0040014 40 0.068
regulation of cell cycle GO:0051726 291 0.065
purine nucleoside biosynthetic process GO:0042451 3 0.065
embryo development ending in birth or egg hatching GO:0009792 152 0.064
spermatid differentiation GO:0048515 114 0.057
regionalization GO:0003002 416 0.055
organonitrogen compound metabolic process GO:1901564 318 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.052
single organism biosynthetic process GO:0044711 206 0.049
male mating behavior GO:0060179 70 0.048
spermatogenesis GO:0007283 200 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
mating behavior GO:0007617 106 0.042
cell proliferation GO:0008283 299 0.042
intracellular transport GO:0046907 228 0.040
organic substance transport GO:0071702 257 0.040
positive regulation of developmental process GO:0051094 143 0.040
neuromuscular junction development GO:0007528 149 0.039
positive regulation of nucleic acid templated transcription GO:1903508 266 0.036
protein complex biogenesis GO:0070271 201 0.034
glycosyl compound biosynthetic process GO:1901659 3 0.034
cell maturation GO:0048469 144 0.034
purine nucleoside catabolic process GO:0006152 112 0.034
male gamete generation GO:0048232 201 0.033
growth GO:0040007 359 0.033
ribonucleotide metabolic process GO:0009259 145 0.032
inter male aggressive behavior GO:0002121 60 0.032
regulation of multicellular organismal development GO:2000026 414 0.032
epithelial cell differentiation GO:0030855 322 0.031
developmental maturation GO:0021700 172 0.030
cell motility GO:0048870 251 0.029
purine nucleotide metabolic process GO:0006163 146 0.028
innate immune response GO:0045087 144 0.028
cell migration GO:0016477 238 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
epidermis development GO:0008544 65 0.024
response to endogenous stimulus GO:0009719 119 0.024
guanosine containing compound catabolic process GO:1901069 74 0.023
nucleoside catabolic process GO:0009164 112 0.023
cellular response to extracellular stimulus GO:0031668 64 0.023
developmental growth GO:0048589 280 0.022
endocytosis GO:0006897 310 0.022
axon development GO:0061564 297 0.022
synapse organization GO:0050808 196 0.022
response to external biotic stimulus GO:0043207 293 0.022
cell projection assembly GO:0030031 94 0.022
phagocytosis GO:0006909 215 0.022
mating GO:0007618 120 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.021
single organism cellular localization GO:1902580 180 0.021
cellular catabolic process GO:0044248 372 0.021
auditory behavior GO:0031223 1 0.020
heterocycle catabolic process GO:0046700 166 0.020
actin cytoskeleton organization GO:0030036 206 0.020
nucleotide metabolic process GO:0009117 161 0.020
locomotory behavior GO:0007626 176 0.020
ribose phosphate metabolic process GO:0019693 145 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
aromatic compound catabolic process GO:0019439 166 0.019
purine ribonucleoside biosynthetic process GO:0046129 3 0.019
centrosome organization GO:0051297 163 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
positive regulation of multicellular organism growth GO:0040018 21 0.018
nucleotide catabolic process GO:0009166 109 0.018
response to organic substance GO:0010033 284 0.018
regulation of response to stress GO:0080134 200 0.018
aggressive behavior GO:0002118 63 0.017
chemotaxis GO:0006935 249 0.017
regulation of developmental growth GO:0048638 174 0.017
body morphogenesis GO:0010171 2 0.017
cellular protein complex assembly GO:0043623 71 0.017
response to extracellular stimulus GO:0009991 116 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
regulation of catalytic activity GO:0050790 185 0.017
catabolic process GO:0009056 409 0.016
mechanosensory behavior GO:0007638 12 0.016
protein localization GO:0008104 284 0.016
rhythmic behavior GO:0007622 76 0.015
response to auditory stimulus GO:0010996 5 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.015
regulation of nervous system development GO:0051960 248 0.015
striated muscle cell differentiation GO:0051146 90 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
sex differentiation GO:0007548 81 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
determination of adult lifespan GO:0008340 137 0.014
embryonic pattern specification GO:0009880 174 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
multicellular organismal aging GO:0010259 140 0.014
positive regulation of gene expression GO:0010628 290 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
larval development GO:0002164 104 0.013
regulation of cell cycle process GO:0010564 181 0.013
defense response GO:0006952 300 0.013
response to starvation GO:0042594 97 0.013
positive regulation of purine nucleotide biosynthetic process GO:1900373 10 0.012
pigment metabolic process GO:0042440 84 0.012
positive regulation of signaling GO:0023056 243 0.012
multicellular organism growth GO:0035264 46 0.012
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
transmembrane transport GO:0055085 139 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
organophosphate biosynthetic process GO:0090407 46 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
establishment of localization in cell GO:0051649 402 0.011
lipid metabolic process GO:0006629 121 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
rna processing GO:0006396 147 0.011
regulation of cellular response to stress GO:0080135 89 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
muscle structure development GO:0061061 224 0.011
cell growth GO:0016049 108 0.011
regulation of autophagy GO:0010506 62 0.011
organic substance catabolic process GO:1901575 308 0.011
peptidyl lysine acetylation GO:0018394 39 0.011
segmentation GO:0035282 207 0.010
response to biotic stimulus GO:0009607 294 0.010
regulation of molecular function GO:0065009 217 0.010

tko disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org