Drosophila melanogaster

48 known processes

Lsp2 (Dmel_CG6806)

Larval serum protein 2

(Aliases: C23,Dmel\CG6806,LSP-2,LSP2,LSP 2,CG6806,DmeLSP2,Pt-1,LHP,CG11538,Lsp-2)

Lsp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to fungus GO:0009620 50 0.443
Fly
defense response to gram positive bacterium GO:0050830 41 0.432
Fly
immune system process GO:0002376 347 0.204
Fly
intracellular protein transmembrane import GO:0044743 4 0.159
Fly
melanotic encapsulation of foreign target GO:0035011 30 0.148
Fly
immune effector process GO:0002252 98 0.147
Fly
chemotaxis GO:0006935 249 0.145
organic hydroxy compound metabolic process GO:1901615 83 0.141
Fly
melanin metabolic process GO:0006582 47 0.127
Fly
response to other organism GO:0051707 293 0.125
Fly
innate immune response GO:0045087 144 0.109
Fly
phenol containing compound metabolic process GO:0018958 57 0.108
Fly
motor neuron axon guidance GO:0008045 58 0.103
defense response to fungus GO:0050832 48 0.101
Fly
intracellular transport GO:0046907 228 0.094
Fly
axon guidance GO:0007411 233 0.094
defense response GO:0006952 300 0.091
Fly
melanization defense response GO:0035006 45 0.090
Fly
response to biotic stimulus GO:0009607 294 0.085
Fly
defense response to other organism GO:0098542 225 0.077
Fly
pigment metabolic process GO:0042440 84 0.077
Fly
response to external biotic stimulus GO:0043207 293 0.075
Fly
secondary metabolic process GO:0019748 75 0.072
Fly
single organism behavior GO:0044708 391 0.071
lateral inhibition GO:0046331 206 0.070
Fly
defense response to bacterium GO:0042742 178 0.067
Fly
neuron projection guidance GO:0097485 241 0.064
axon development GO:0061564 297 0.063
immune response GO:0006955 246 0.063
Fly
single organism intracellular transport GO:1902582 207 0.058
Fly
protein transmembrane transport GO:0071806 4 0.058
Fly
response to bacterium GO:0009617 198 0.057
Fly
cellular macromolecule localization GO:0070727 220 0.055
Fly
protein localization GO:0008104 284 0.051
Fly
imaginal disc derived appendage development GO:0048737 399 0.051
neuron recognition GO:0008038 101 0.050
vesicle mediated transport GO:0016192 381 0.049
taxis GO:0042330 304 0.049
immune response regulating signaling pathway GO:0002764 2 0.048
developmental programmed cell death GO:0010623 138 0.048
cell death GO:0008219 279 0.047
establishment of localization in cell GO:0051649 402 0.047
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.044
Fly
exocrine system development GO:0035272 162 0.044
g protein coupled receptor signaling pathway GO:0007186 136 0.042
protein transport GO:0015031 155 0.041
Fly
immune response activating signal transduction GO:0002757 2 0.041
oxoacid metabolic process GO:0043436 103 0.041
intracellular protein transmembrane transport GO:0065002 4 0.039
Fly
acetaldehyde metabolic process GO:0006117 5 0.039
response to abiotic stimulus GO:0009628 341 0.039
organic substance transport GO:0071702 257 0.038
Fly
cell proliferation GO:0008283 299 0.037
cellular catabolic process GO:0044248 372 0.036
cellular protein modification process GO:0006464 438 0.036
histolysis GO:0007559 102 0.035
salivary gland histolysis GO:0035070 88 0.035
eye development GO:0001654 323 0.034
regulation of immune response GO:0050776 118 0.034
tissue death GO:0016271 102 0.033
regulation of response to stress GO:0080134 200 0.033
phagocytosis GO:0006909 215 0.032
protein modification process GO:0036211 438 0.031
camera type eye development GO:0043010 4 0.031
gland development GO:0048732 191 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
zymogen activation GO:0031638 20 0.030
organic acid metabolic process GO:0006082 103 0.030
appendage development GO:0048736 401 0.030
neurological system process GO:0050877 358 0.030
regulation of multicellular organismal development GO:2000026 414 0.030
regulation of response to biotic stimulus GO:0002831 63 0.029
extracellular structure organization GO:0043062 46 0.029
salivary gland development GO:0007431 162 0.029
appendage morphogenesis GO:0035107 397 0.029
regulation of cell cycle GO:0051726 291 0.028
wing disc morphogenesis GO:0007472 344 0.028
positive regulation of response to stimulus GO:0048584 323 0.028
compound eye development GO:0048749 307 0.028
homeostatic process GO:0042592 199 0.027
small molecule metabolic process GO:0044281 305 0.027
intracellular protein transport GO:0006886 104 0.027
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.027
cellular amine metabolic process GO:0044106 12 0.027
salivary gland cell autophagic cell death GO:0035071 83 0.027
axonogenesis GO:0007409 290 0.027
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
transmembrane transport GO:0055085 139 0.026
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.026
positive regulation of cell communication GO:0010647 250 0.026
single organism catabolic process GO:0044712 228 0.026
endocytosis GO:0006897 310 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
eye morphogenesis GO:0048592 260 0.024
response to lipopolysaccharide GO:0032496 4 0.024
apical junction assembly GO:0043297 32 0.024
sensory organ morphogenesis GO:0090596 260 0.024
regulation of phosphate metabolic process GO:0019220 210 0.024
autophagic cell death GO:0048102 83 0.024
pattern recognition receptor signaling pathway GO:0002221 2 0.024
cellular response to lipopolysaccharide GO:0071222 3 0.023
cellular response to organic substance GO:0071310 132 0.023
antimicrobial humoral response GO:0019730 99 0.023
cell recognition GO:0008037 102 0.023
intracellular signal transduction GO:0035556 300 0.023
regulation of immune system process GO:0002682 176 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
ion transport GO:0006811 145 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
cellular protein localization GO:0034613 160 0.022
Fly
death GO:0016265 284 0.022
neutral lipid biosynthetic process GO:0046460 2 0.022
neural precursor cell proliferation GO:0061351 75 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
sulfur compound biosynthetic process GO:0044272 16 0.021
programmed cell death GO:0012501 257 0.021
compound eye morphogenesis GO:0001745 249 0.021
catabolic process GO:0009056 409 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
gland morphogenesis GO:0022612 145 0.021
positive regulation of signaling GO:0023056 243 0.021
regionalization GO:0003002 416 0.021
regulation of defense response GO:0031347 102 0.021
humoral immune response GO:0006959 117 0.020
establishment of protein localization GO:0045184 163 0.020
Fly
regulation of multi organism process GO:0043900 131 0.020
hindbrain development GO:0030902 2 0.020
regulation of nervous system development GO:0051960 248 0.020
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.020
regulation of catalytic activity GO:0050790 185 0.020
mitotic nuclear division GO:0007067 213 0.020
organic substance catabolic process GO:1901575 308 0.020
regulation of cell proliferation GO:0042127 163 0.019
response to organic substance GO:0010033 284 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
cellular response to biotic stimulus GO:0071216 4 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
regulation of cellular response to stress GO:0080135 89 0.019
negative regulation of cell communication GO:0010648 223 0.019
positive regulation of immune response GO:0050778 63 0.019
response to endogenous stimulus GO:0009719 119 0.018
chemosensory behavior GO:0007635 106 0.018
macromolecular complex assembly GO:0065003 256 0.018
nucleoside metabolic process GO:0009116 127 0.018
encapsulation of foreign target GO:0035010 38 0.018
Fly
nuclear division GO:0000280 332 0.017
neuropeptide signaling pathway GO:0007218 45 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
positive regulation of cell migration GO:0030335 2 0.017
positive regulation of signal transduction GO:0009967 223 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
sulfur compound metabolic process GO:0006790 59 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
kidney development GO:0001822 3 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
organelle fission GO:0048285 340 0.017
response to monosaccharide GO:0034284 4 0.017
response to organophosphorus GO:0046683 2 0.017
regulation of membrane potential GO:0042391 35 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
epithelial cell differentiation GO:0030855 322 0.016
regulation of cell development GO:0060284 215 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
spindle organization GO:0007051 253 0.016
amine metabolic process GO:0009308 12 0.016
limb development GO:0060173 1 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
male courtship behavior veined wing generated song production GO:0045433 20 0.016
antibacterial humoral response GO:0019731 44 0.016
response to oxygen containing compound GO:1901700 200 0.016
salivary gland morphogenesis GO:0007435 145 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
developmental maturation GO:0021700 172 0.016
regulation of molecular function GO:0065009 217 0.016
rhabdomere development GO:0042052 38 0.016
protein processing GO:0016485 68 0.016
phosphorylation GO:0016310 294 0.016
purine containing compound metabolic process GO:0072521 155 0.016
axis specification GO:0009798 167 0.016
response to temperature stimulus GO:0009266 106 0.016
response to alcohol GO:0097305 95 0.015
body morphogenesis GO:0010171 2 0.015
regulation of cell cycle process GO:0010564 181 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
organophosphate metabolic process GO:0019637 195 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
regulation of phosphorylation GO:0042325 147 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
protein maturation GO:0051604 71 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
forebrain development GO:0030900 2 0.015
anatomical structure homeostasis GO:0060249 97 0.015
positive regulation of molecular function GO:0044093 136 0.015
limb morphogenesis GO:0035108 1 0.015
positive regulation of cell motility GO:2000147 3 0.015
connective tissue development GO:0061448 3 0.015
regulation of localization GO:0032879 275 0.014
acetylcholine metabolic process GO:0008291 2 0.014
ovarian follicle cell development GO:0030707 248 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
triglyceride biosynthetic process GO:0019432 2 0.014
telencephalon development GO:0021537 2 0.014
regulation of response to external stimulus GO:0032101 115 0.014
negative regulation of gene expression GO:0010629 387 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
proteolysis GO:0006508 192 0.014
synaptic target recognition GO:0008039 45 0.014
vitamin biosynthetic process GO:0009110 1 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
aromatic compound catabolic process GO:0019439 166 0.014
negative regulation of signaling GO:0023057 219 0.014
regulation of innate immune response GO:0045088 71 0.014
transition metal ion transport GO:0000041 16 0.014
fat soluble vitamin metabolic process GO:0006775 1 0.014
smoothened signaling pathway GO:0007224 49 0.014
response to copper ion GO:0046688 4 0.014
neurotransmitter metabolic process GO:0042133 2 0.014
response to hexose GO:0009746 3 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
acylglycerol biosynthetic process GO:0046463 2 0.014
negative chemotaxis GO:0050919 15 0.014
cellular modified amino acid metabolic process GO:0006575 45 0.014
monocarboxylic acid transport GO:0015718 3 0.013
open tracheal system development GO:0007424 204 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.013
epithelium migration GO:0090132 148 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
positive regulation of developmental process GO:0051094 143 0.013
negative regulation of signal transduction GO:0009968 206 0.013
male mating behavior GO:0060179 70 0.013
protein complex biogenesis GO:0070271 201 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
regulation of protein metabolic process GO:0051246 256 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
retina development in camera type eye GO:0060041 4 0.013
response to heat GO:0009408 63 0.013
cholesterol homeostasis GO:0042632 3 0.013
cholesterol transport GO:0030301 2 0.013
regulation of programmed cell death GO:0043067 152 0.013
peptidyl lysine modification GO:0018205 57 0.013
cation transport GO:0006812 110 0.013
negative regulation of immune system process GO:0002683 50 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
behavioral response to ethanol GO:0048149 49 0.013
acetate ester metabolic process GO:1900619 2 0.013
positive regulation of transcription dna templated GO:0045893 266 0.012
regulation of cell death GO:0010941 173 0.012
macromolecule catabolic process GO:0009057 161 0.012
sensory perception GO:0007600 196 0.012
organic hydroxy compound catabolic process GO:1901616 4 0.012
response to organic cyclic compound GO:0014070 89 0.012
vitamin metabolic process GO:0006766 2 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
nitrogen compound transport GO:0071705 85 0.012
central nervous system development GO:0007417 201 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
protein import GO:0017038 55 0.012
Fly
adult behavior GO:0030534 137 0.012
muscle organ development GO:0007517 127 0.012
rna localization GO:0006403 115 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
cell motility GO:0048870 251 0.012
regulation of cell differentiation GO:0045595 302 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
molting cycle chitin based cuticle GO:0007591 56 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
positive regulation of nervous system development GO:0051962 69 0.012
s adenosylmethionine cycle GO:0033353 3 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
chromosome segregation GO:0007059 157 0.012
mesenchymal cell development GO:0014031 1 0.012
wnt signaling pathway GO:0016055 98 0.012
positive regulation of catabolic process GO:0009896 105 0.012
apoptotic process involved in morphogenesis GO:0060561 3 0.011
regulation of cellular localization GO:0060341 136 0.011
protein complex assembly GO:0006461 200 0.011
single organism biosynthetic process GO:0044711 206 0.011
photoreceptor cell development GO:0042461 96 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
positive regulation of immune system process GO:0002684 68 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
cellular response to heat GO:0034605 24 0.011
epithelial cell development GO:0002064 274 0.011
negative regulation of cell cycle GO:0045786 116 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
wound healing GO:0042060 75 0.011
localization of cell GO:0051674 257 0.011
response to wounding GO:0009611 94 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
ras protein signal transduction GO:0007265 88 0.011
acylglycerol catabolic process GO:0046464 3 0.011
olfactory behavior GO:0042048 97 0.011
positive regulation of cell development GO:0010720 61 0.011
positive regulation of defense response GO:0031349 59 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
cell adhesion GO:0007155 136 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
dorsal ventral axis specification GO:0009950 66 0.011
eye antennal disc development GO:0035214 60 0.011
peptide metabolic process GO:0006518 80 0.011
tripartite regional subdivision GO:0007351 103 0.011
nucleotide metabolic process GO:0009117 161 0.011
regulation of cholesterol transport GO:0032374 1 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of neurogenesis GO:0050767 158 0.011
cell division GO:0051301 248 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.011
regulation of hydrolase activity GO:0051336 97 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
cellular ketone metabolic process GO:0042180 24 0.011
single organism cellular localization GO:1902580 180 0.011
positive regulation of gene expression GO:0010628 290 0.011
extracellular matrix organization GO:0030198 32 0.011
heterocycle catabolic process GO:0046700 166 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
multi multicellular organism process GO:0044706 123 0.011
blastoderm segmentation GO:0007350 159 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
sterol homeostasis GO:0055092 4 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
dendrite morphogenesis GO:0048813 199 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
regulation of sterol transport GO:0032371 1 0.010
cellular response to monosaccharide stimulus GO:0071326 2 0.010
chemical homeostasis GO:0048878 92 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
eye photoreceptor cell development GO:0042462 81 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
meiotic cell cycle GO:0051321 171 0.010
camera type eye morphogenesis GO:0048593 2 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
nephron development GO:0072006 3 0.010
glycerolipid catabolic process GO:0046503 3 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
cell cell junction organization GO:0045216 55 0.010
male gamete generation GO:0048232 201 0.010
embryonic axis specification GO:0000578 107 0.010

Lsp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.036
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.020
acquired metabolic disease DOID:0060158 0 0.014
central nervous system disease DOID:331 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
familial lipoprotein lipase deficiency DOID:14118 0 0.012
familial hyperlipidemia DOID:1168 0 0.012
lipid metabolism disorder DOID:3146 0 0.012
integumentary system disease DOID:16 0 0.011