Drosophila melanogaster

0 known processes

spz6 (Dmel_CG9196)

spatzle 6

(Aliases: Spz6,CG9196,Dmel\CG9196,CT26280,BcDNA:LP10725)

spz6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.088
epithelial cell differentiation GO:0030855 322 0.073
small molecule metabolic process GO:0044281 305 0.071
actin filament based process GO:0030029 220 0.069
actin cytoskeleton organization GO:0030036 206 0.065
appendage development GO:0048736 401 0.060
imaginal disc derived appendage morphogenesis GO:0035114 395 0.057
organic acid metabolic process GO:0006082 103 0.057
actin filament organization GO:0007015 126 0.051
epithelial cell development GO:0002064 274 0.051
biological adhesion GO:0022610 138 0.050
sensory perception GO:0007600 196 0.049
carboxylic acid metabolic process GO:0019752 92 0.049
oxoacid metabolic process GO:0043436 103 0.047
appendage morphogenesis GO:0035107 397 0.047
cellular amino acid metabolic process GO:0006520 61 0.045
imaginal disc derived appendage development GO:0048737 399 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.043
imaginal disc derived wing morphogenesis GO:0007476 337 0.042
lateral inhibition GO:0046331 206 0.042
negative regulation of gene expression GO:0010629 387 0.039
eye pigment metabolic process GO:0042441 33 0.038
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.038
regulation of multicellular organismal development GO:2000026 414 0.038
wing disc morphogenesis GO:0007472 344 0.037
single organism biosynthetic process GO:0044711 206 0.037
neurological system process GO:0050877 358 0.037
cellular modified amino acid metabolic process GO:0006575 45 0.037
pigment metabolic process involved in pigmentation GO:0043474 33 0.036
cell adhesion GO:0007155 136 0.036
cellular ketone metabolic process GO:0042180 24 0.035
developmental pigmentation GO:0048066 68 0.035
defense response GO:0006952 300 0.035
pigment metabolic process GO:0042440 84 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
response to other organism GO:0051707 293 0.034
ethanolamine containing compound metabolic process GO:0042439 4 0.033
lipid metabolic process GO:0006629 121 0.033
response to biotic stimulus GO:0009607 294 0.032
vesicle mediated transport GO:0016192 381 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
response to external biotic stimulus GO:0043207 293 0.031
body morphogenesis GO:0010171 2 0.031
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
dendrite development GO:0016358 204 0.030
benzene containing compound metabolic process GO:0042537 3 0.030
response to organic substance GO:0010033 284 0.030
estrogen metabolic process GO:0008210 1 0.029
anion homeostasis GO:0055081 3 0.028
regulation of localization GO:0032879 275 0.028
defense response to bacterium GO:0042742 178 0.028
response to extracellular stimulus GO:0009991 116 0.027
cellular catabolic process GO:0044248 372 0.027
dendrite morphogenesis GO:0048813 199 0.027
regionalization GO:0003002 416 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
catabolic process GO:0009056 409 0.027
response to abiotic stimulus GO:0009628 341 0.026
regulation of hormone levels GO:0010817 40 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.026
response to oxygen containing compound GO:1901700 200 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
cell death GO:0008219 279 0.026
transcription from rna polymerase ii promoter GO:0006366 368 0.026
organic hydroxy compound metabolic process GO:1901615 83 0.025
organic substance catabolic process GO:1901575 308 0.025
endocytosis GO:0006897 310 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
pigment biosynthetic process GO:0046148 36 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.024
gene silencing GO:0016458 138 0.024
protein modification process GO:0036211 438 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
pigmentation GO:0043473 75 0.024
phagocytosis GO:0006909 215 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
death GO:0016265 284 0.023
positive regulation of signaling GO:0023056 243 0.023
positive regulation of biosynthetic process GO:0009891 316 0.022
defense response to other organism GO:0098542 225 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
single organism catabolic process GO:0044712 228 0.022
regulation of catalytic activity GO:0050790 185 0.022
positive regulation of signal transduction GO:0009967 223 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
amine metabolic process GO:0009308 12 0.021
positive regulation of cell communication GO:0010647 250 0.021
salivary gland development GO:0007431 162 0.021
developmental growth GO:0048589 280 0.021
cellular amine metabolic process GO:0044106 12 0.021
compound eye development GO:0048749 307 0.021
growth GO:0040007 359 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
eye development GO:0001654 323 0.021
regulation of molecular function GO:0065009 217 0.021
response to organophosphorus GO:0046683 2 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
negative regulation of signal transduction GO:0009968 206 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
response to lipopolysaccharide GO:0032496 4 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
response to nutrient levels GO:0031667 114 0.020
aging GO:0007568 143 0.020
eye morphogenesis GO:0048592 260 0.020
cellular amide metabolic process GO:0043603 80 0.020
positive regulation of cell migration GO:0030335 2 0.020
intracellular signal transduction GO:0035556 300 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
eye pigmentation GO:0048069 43 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
ocellus pigment biosynthetic process GO:0008055 19 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
response to endogenous stimulus GO:0009719 119 0.019
gland morphogenesis GO:0022612 145 0.019
protein localization GO:0008104 284 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
actin mediated cell contraction GO:0070252 21 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
cellular protein modification process GO:0006464 438 0.018
regulation of cell differentiation GO:0045595 302 0.018
regulation of gene silencing GO:0060968 63 0.018
gene silencing by rna GO:0031047 57 0.018
steroid catabolic process GO:0006706 1 0.018
immune response activating signal transduction GO:0002757 2 0.018
homeostatic process GO:0042592 199 0.018
programmed cell death GO:0012501 257 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
regulation of cell shape GO:0008360 113 0.018
proteolysis GO:0006508 192 0.018
developmental programmed cell death GO:0010623 138 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
positive regulation of gene expression GO:0010628 290 0.018
establishment of localization in cell GO:0051649 402 0.018
regulation of transport GO:0051049 181 0.018
negative regulation of cell communication GO:0010648 223 0.018
organelle fission GO:0048285 340 0.017
camera type eye development GO:0043010 4 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
organophosphate metabolic process GO:0019637 195 0.017
ras protein signal transduction GO:0007265 88 0.017
peptide metabolic process GO:0006518 80 0.017
sensory organ morphogenesis GO:0090596 260 0.017
triglyceride biosynthetic process GO:0019432 2 0.017
ovarian follicle cell development GO:0030707 248 0.017
ocellus pigment metabolic process GO:0046158 19 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
regulation of cell death GO:0010941 173 0.017
forebrain development GO:0030900 2 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
compound eye morphogenesis GO:0001745 249 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
taxis GO:0042330 304 0.017
response to organic cyclic compound GO:0014070 89 0.017
positive regulation of cell motility GO:2000147 3 0.017
eye pigment biosynthetic process GO:0006726 32 0.017
autophagic cell death GO:0048102 83 0.017
ommochrome metabolic process GO:0046152 19 0.017
regulation of protein metabolic process GO:0051246 256 0.017
cell division GO:0051301 248 0.016
axon development GO:0061564 297 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
respiratory system development GO:0060541 213 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
exocrine system development GO:0035272 162 0.016
phosphorylation GO:0016310 294 0.016
regulation of embryonic development GO:0045995 68 0.016
phenol containing compound metabolic process GO:0018958 57 0.016
organic substance transport GO:0071702 257 0.016
regulation of programmed cell death GO:0043067 152 0.015
regulation of nervous system development GO:0051960 248 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
macromolecular complex assembly GO:0065003 256 0.015
regulation of hydrolase activity GO:0051336 97 0.015
response to bacterium GO:0009617 198 0.015
acetylcholine metabolic process GO:0008291 2 0.015
sterol homeostasis GO:0055092 4 0.015
regulation of multi organism process GO:0043900 131 0.015
negative regulation of signaling GO:0023057 219 0.015
connective tissue development GO:0061448 3 0.015
cellular hormone metabolic process GO:0034754 23 0.015
neurotransmitter metabolic process GO:0042133 2 0.015
open tracheal system development GO:0007424 204 0.015
immune system process GO:0002376 347 0.015
cholesterol homeostasis GO:0042632 3 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.014
salivary gland morphogenesis GO:0007435 145 0.014
cellular response to nutrient levels GO:0031669 62 0.014
segmentation GO:0035282 207 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
localization of cell GO:0051674 257 0.014
cell motility GO:0048870 251 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
regulation of response to stress GO:0080134 200 0.014
synaptic transmission GO:0007268 288 0.014
single organism behavior GO:0044708 391 0.014
regulation of cell cycle GO:0051726 291 0.014
cellular response to organic substance GO:0071310 132 0.014
regulation of growth GO:0040008 233 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
cuticle development GO:0042335 86 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
neutral lipid biosynthetic process GO:0046460 2 0.014
response to monosaccharide GO:0034284 4 0.014
response to alcohol GO:0097305 95 0.014
regulation of cell development GO:0060284 215 0.014
regulation of anatomical structure size GO:0090066 163 0.014
ommochrome biosynthetic process GO:0006727 19 0.014
spindle organization GO:0007051 253 0.014
hormone metabolic process GO:0042445 33 0.014
regulation of catabolic process GO:0009894 170 0.014
actin filament based movement GO:0030048 26 0.014
cellular lipid metabolic process GO:0044255 83 0.014
nuclear division GO:0000280 332 0.014
heterocycle catabolic process GO:0046700 166 0.014
aromatic compound catabolic process GO:0019439 166 0.014
organelle assembly GO:0070925 198 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
cellular macromolecule localization GO:0070727 220 0.013
regulation of developmental growth GO:0048638 174 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
secondary metabolite biosynthetic process GO:0044550 24 0.013
axonogenesis GO:0007409 290 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
regulation of immune response GO:0050776 118 0.013
gland development GO:0048732 191 0.013
regulation of cell cycle process GO:0010564 181 0.013
mating GO:0007618 120 0.013
leg disc development GO:0035218 92 0.013
antifungal humoral response GO:0019732 12 0.013
tissue death GO:0016271 102 0.013
actin filament bundle assembly GO:0051017 26 0.013
phospholipid homeostasis GO:0055091 1 0.013
intracellular transport GO:0046907 228 0.013
nucleotide metabolic process GO:0009117 161 0.013
negative regulation of developmental process GO:0051093 201 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
acylglycerol biosynthetic process GO:0046463 2 0.013
acylglycerol catabolic process GO:0046464 3 0.013
cell proliferation GO:0008283 299 0.013
purine containing compound metabolic process GO:0072521 155 0.013
chromosome organization GO:0051276 360 0.013
macromolecule catabolic process GO:0009057 161 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
maintenance of location GO:0051235 73 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
positive regulation of cell death GO:0010942 69 0.013
rho protein signal transduction GO:0007266 14 0.013
polyol biosynthetic process GO:0046173 3 0.013
response to toxic substance GO:0009636 22 0.013
antimicrobial humoral response GO:0019730 99 0.013
telencephalon development GO:0021537 2 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
chemotaxis GO:0006935 249 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
multi organism reproductive behavior GO:0044705 121 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
apical constriction GO:0003383 18 0.012
salivary gland histolysis GO:0035070 88 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
notch signaling pathway GO:0007219 120 0.012
hormone catabolic process GO:0042447 3 0.012
histolysis GO:0007559 102 0.012
amine catabolic process GO:0009310 1 0.012
establishment of protein localization GO:0045184 163 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
developmental maturation GO:0021700 172 0.012
regulation of lipid transport GO:0032368 3 0.012
leg disc morphogenesis GO:0007478 80 0.012
embryonic pattern specification GO:0009880 174 0.012
dephosphorylation GO:0016311 51 0.012
response to light stimulus GO:0009416 124 0.012
activation of innate immune response GO:0002218 4 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
phosphatidylethanolamine metabolic process GO:0046337 1 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
endomembrane system organization GO:0010256 119 0.012
secondary metabolic process GO:0019748 75 0.012
glycerolipid catabolic process GO:0046503 3 0.012
fat soluble vitamin metabolic process GO:0006775 1 0.012
xenobiotic catabolic process GO:0042178 1 0.012
sensory perception of sound GO:0007605 56 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
vitamin biosynthetic process GO:0009110 1 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
regulation of response to external stimulus GO:0032101 115 0.012
immune response GO:0006955 246 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
phosphatidic acid metabolic process GO:0046473 1 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
protein transport GO:0015031 155 0.012
limb development GO:0060173 1 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
blastoderm segmentation GO:0007350 159 0.012
spermatogenesis GO:0007283 200 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.011
multi multicellular organism process GO:0044706 123 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
humoral immune response GO:0006959 117 0.011
organophosphate catabolic process GO:0046434 112 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
acetate ester metabolic process GO:1900619 2 0.011
androgen metabolic process GO:0008209 1 0.011
axis specification GO:0009798 167 0.011
response to glucose GO:0009749 2 0.011
cellular protein localization GO:0034613 160 0.011
triglyceride catabolic process GO:0019433 3 0.011
cellular response to ethanol GO:0071361 4 0.011
regulation of defense response GO:0031347 102 0.011
male gamete generation GO:0048232 201 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
mesenchymal cell development GO:0014031 1 0.011
organelle localization GO:0051640 148 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
chromatin remodeling GO:0006338 72 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
single organism intracellular transport GO:1902582 207 0.011
synapse assembly GO:0007416 143 0.011
regulation of sequestering of triglyceride GO:0010889 3 0.011
choline metabolic process GO:0019695 1 0.011
retina development in camera type eye GO:0060041 4 0.011
response to radiation GO:0009314 155 0.011
tissue migration GO:0090130 155 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
meiotic cell cycle GO:0051321 171 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
wnt signaling pathway GO:0016055 98 0.011
chromosome segregation GO:0007059 157 0.011
male mating behavior GO:0060179 70 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
camera type eye morphogenesis GO:0048593 2 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
l glutamate import GO:0051938 1 0.011
regulation of apoptotic process GO:0042981 130 0.011
cholesterol transport GO:0030301 2 0.011
hindbrain development GO:0030902 2 0.011
kidney development GO:0001822 3 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
immune effector process GO:0002252 98 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of catabolic process GO:0009896 105 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
cellular response to oxygen containing compound GO:1901701 79 0.010
axon guidance GO:0007411 233 0.010
regulation of organelle organization GO:0033043 196 0.010
ameboidal type cell migration GO:0001667 151 0.010
regulation of proteolysis GO:0030162 87 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
rna processing GO:0006396 147 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
regulation of cellular localization GO:0060341 136 0.010
negative regulation of defense response GO:0031348 35 0.010
protein heterooligomerization GO:0051291 4 0.010
mitotic nuclear division GO:0007067 213 0.010
acetylcholine catabolic process GO:0006581 1 0.010
chromatin modification GO:0016568 147 0.010
female meiotic division GO:0007143 70 0.010
protein processing GO:0016485 68 0.010
nucleoside metabolic process GO:0009116 127 0.010
response to insecticide GO:0017085 14 0.010
ocellus pigmentation GO:0033060 19 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
muscle organ development GO:0007517 127 0.010
rna localization GO:0006403 115 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
mitotic spindle organization GO:0007052 220 0.010
negative regulation of molecular function GO:0044092 51 0.010

spz6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.029
disease of metabolism DOID:0014667 0 0.020
sensory system disease DOID:0050155 0 0.016
inherited metabolic disorder DOID:655 0 0.015
diabetes mellitus DOID:9351 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
carbohydrate metabolism disease DOID:0050013 0 0.014
glucose metabolism disease DOID:4194 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
cardiovascular system disease DOID:1287 0 0.012
eye and adnexa disease DOID:1492 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
central nervous system disease DOID:331 0 0.010
cancer DOID:162 0 0.010
eye disease DOID:5614 0 0.010