Drosophila melanogaster

0 known processes

Cdlc2 (Dmel_CG5450)

Cytoplasmic dynein light chain 2

(Aliases: dlc,Dmel\CG5450,CG5450,anon-WO0140519.117,Cdcl2)

Cdlc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.306
Fly
appendage morphogenesis GO:0035107 397 0.179
Fly
single organism biosynthetic process GO:0044711 206 0.153
positive regulation of phosphate metabolic process GO:0045937 139 0.148
post embryonic appendage morphogenesis GO:0035120 385 0.145
Fly
wing disc morphogenesis GO:0007472 344 0.138
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.136
positive regulation of cellular biosynthetic process GO:0031328 316 0.109
catabolic process GO:0009056 409 0.108
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.106
imaginal disc derived appendage development GO:0048737 399 0.092
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.089
innate immune response GO:0045087 144 0.087
organophosphate metabolic process GO:0019637 195 0.086
cellular lipid metabolic process GO:0044255 83 0.084
apoptotic process GO:0006915 159 0.079
defense response GO:0006952 300 0.079
regulation of cell cycle GO:0051726 291 0.075
lipid metabolic process GO:0006629 121 0.075
death GO:0016265 284 0.074
Fly
positive regulation of rna metabolic process GO:0051254 271 0.074
organic hydroxy compound metabolic process GO:1901615 83 0.073
regulation of molecular function GO:0065009 217 0.072
organophosphate catabolic process GO:0046434 112 0.070
response to wounding GO:0009611 94 0.069
negative regulation of gene expression GO:0010629 387 0.068
positive regulation of catalytic activity GO:0043085 118 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.062
regulation of phosphorus metabolic process GO:0051174 210 0.060
establishment or maintenance of cell polarity GO:0007163 167 0.060
Fly
positive regulation of phosphorylation GO:0042327 87 0.058
positive regulation of phosphorus metabolic process GO:0010562 139 0.056
positive regulation of transcription dna templated GO:0045893 266 0.056
melanin metabolic process GO:0006582 47 0.056
intracellular signal transduction GO:0035556 300 0.055
regulation of phosphate metabolic process GO:0019220 210 0.054
positive regulation of cellular protein metabolic process GO:0032270 118 0.054
small molecule metabolic process GO:0044281 305 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
positive regulation of macromolecule metabolic process GO:0010604 405 0.051
positive regulation of molecular function GO:0044093 136 0.050
regulation of cell proliferation GO:0042127 163 0.049
positive regulation of cell communication GO:0010647 250 0.046
organelle assembly GO:0070925 198 0.046
organic substance catabolic process GO:1901575 308 0.046
mating GO:0007618 120 0.044
melanotic encapsulation of foreign target GO:0035011 30 0.044
programmed cell death GO:0012501 257 0.044
Fly
lipid biosynthetic process GO:0008610 46 0.044
response to mercury ion GO:0046689 3 0.044
positive regulation of gene expression GO:0010628 290 0.044
melanization defense response GO:0035006 45 0.044
positive regulation of response to stimulus GO:0048584 323 0.043
organonitrogen compound metabolic process GO:1901564 318 0.042
spermatogenesis GO:0007283 200 0.040
Fly
positive regulation of signaling GO:0023056 243 0.040
immune effector process GO:0002252 98 0.040
cell death GO:0008219 279 0.039
Fly
regulation of phosphorylation GO:0042325 147 0.039
flight behavior GO:0007629 26 0.038
body morphogenesis GO:0010171 2 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
Fly
phosphorylation GO:0016310 294 0.037
cellular protein localization GO:0034613 160 0.037
Fly
positive regulation of signal transduction GO:0009967 223 0.037
pigment metabolic process GO:0042440 84 0.036
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.036
cellular response to chemical stimulus GO:0070887 199 0.036
negative regulation of protein metabolic process GO:0051248 85 0.035
negative regulation of biosynthetic process GO:0009890 277 0.035
organophosphate biosynthetic process GO:0090407 46 0.035
organic acid metabolic process GO:0006082 103 0.034
positive regulation of protein kinase activity GO:0045860 25 0.033
positive regulation of transferase activity GO:0051347 26 0.033
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.033
cellular ion homeostasis GO:0006873 39 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.032
positive regulation of intracellular signal transduction GO:1902533 116 0.031
negative regulation of response to stimulus GO:0048585 258 0.031
transcription from rna polymerase ii promoter GO:0006366 368 0.031
carbohydrate metabolic process GO:0005975 82 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.030
lateral inhibition GO:0046331 206 0.030
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.029
homeostatic process GO:0042592 199 0.029
encapsulation of foreign target GO:0035010 38 0.029
small molecule catabolic process GO:0044282 21 0.029
appendage development GO:0048736 401 0.029
Fly
protein complex assembly GO:0006461 200 0.029
response to lipopolysaccharide GO:0032496 4 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
multi organism behavior GO:0051705 175 0.028
multi multicellular organism process GO:0044706 123 0.028
sensory perception of mechanical stimulus GO:0050954 72 0.027
spindle assembly GO:0051225 80 0.027
cell proliferation GO:0008283 299 0.027
single organism cellular localization GO:1902580 180 0.027
Fly
positive regulation of biosynthetic process GO:0009891 316 0.026
regulation of peptidase activity GO:0052547 39 0.026
regulation of transferase activity GO:0051338 58 0.026
regulation of protein metabolic process GO:0051246 256 0.026
regulation of cell differentiation GO:0045595 302 0.026
nucleotide metabolic process GO:0009117 161 0.025
cilium morphogenesis GO:0060271 39 0.025
protein processing GO:0016485 68 0.024
chemical homeostasis GO:0048878 92 0.024
cellular protein modification process GO:0006464 438 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
neurological system process GO:0050877 358 0.023
oxoacid metabolic process GO:0043436 103 0.023
multicellular organismal reproductive behavior GO:0033057 110 0.023
response to biotic stimulus GO:0009607 294 0.023
phenol containing compound metabolic process GO:0018958 57 0.023
single organism carbohydrate metabolic process GO:0044723 72 0.022
cellular response to organic substance GO:0071310 132 0.022
chromosome organization GO:0051276 360 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
detection of stimulus GO:0051606 156 0.021
axon development GO:0061564 297 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
response to nitrogen compound GO:1901698 90 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
chromosome segregation GO:0007059 157 0.020
cation homeostasis GO:0055080 51 0.020
positive regulation of protein phosphorylation GO:0001934 34 0.020
protein maturation GO:0051604 71 0.020
stem cell differentiation GO:0048863 117 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
cellular catabolic process GO:0044248 372 0.020
Fly
forebrain development GO:0030900 2 0.020
glycerolipid metabolic process GO:0046486 34 0.020
response to abiotic stimulus GO:0009628 341 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
response to organic cyclic compound GO:0014070 89 0.019
regulation of catalytic activity GO:0050790 185 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
male gamete generation GO:0048232 201 0.019
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
positive regulation of multi organism process GO:0043902 40 0.019
regulation of protein phosphorylation GO:0001932 64 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
response to inorganic substance GO:0010035 44 0.018
chaeta development GO:0022416 97 0.018
Fly
immune system process GO:0002376 347 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
response to organic substance GO:0010033 284 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
glycerophospholipid metabolic process GO:0006650 23 0.018
single organism catabolic process GO:0044712 228 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
taxis GO:0042330 304 0.017
response to organophosphorus GO:0046683 2 0.017
wound healing GO:0042060 75 0.017
neurotransmitter metabolic process GO:0042133 2 0.017
regulation of cellular component biogenesis GO:0044087 201 0.016
locomotory behavior GO:0007626 176 0.016
spindle organization GO:0007051 253 0.016
proteolysis GO:0006508 192 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
protein modification process GO:0036211 438 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
regulation of anatomical structure size GO:0090066 163 0.016
macromolecule catabolic process GO:0009057 161 0.016
protein localization GO:0008104 284 0.016
Fly
regulation of kinase activity GO:0043549 53 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
cellular carbohydrate metabolic process GO:0044262 22 0.016
endocytosis GO:0006897 310 0.015
chemotaxis GO:0006935 249 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
monocarboxylic acid transport GO:0015718 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
tissue death GO:0016271 102 0.015
Fly
sensory perception GO:0007600 196 0.015
alcohol metabolic process GO:0006066 25 0.015
regulation of hydrolase activity GO:0051336 97 0.015
response to organonitrogen compound GO:0010243 75 0.015
positive regulation of kinase activity GO:0033674 25 0.015
polyol biosynthetic process GO:0046173 3 0.014
male meiosis GO:0007140 52 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
cell division GO:0051301 248 0.014
lipid homeostasis GO:0055088 33 0.014
cellular macromolecule localization GO:0070727 220 0.014
Fly
positive regulation of protein binding GO:0032092 1 0.014
phagocytosis GO:0006909 215 0.014
vesicle mediated transport GO:0016192 381 0.014
telencephalon development GO:0021537 2 0.013
adult locomotory behavior GO:0008344 76 0.013
circulatory system development GO:0072359 82 0.013
nitrogen compound transport GO:0071705 85 0.013
chromatin modification GO:0016568 147 0.013
positive regulation of defense response GO:0031349 59 0.013
cellular homeostasis GO:0019725 80 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
neuron projection guidance GO:0097485 241 0.013
purine containing compound catabolic process GO:0072523 112 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
regulation of cellular component size GO:0032535 98 0.013
response to bacterium GO:0009617 198 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
response to endogenous stimulus GO:0009719 119 0.013
regulation of cell death GO:0010941 173 0.013
axon guidance GO:0007411 233 0.012
response to oxygen containing compound GO:1901700 200 0.012
nucleotide catabolic process GO:0009166 109 0.012
small molecule biosynthetic process GO:0044283 37 0.012
immune response GO:0006955 246 0.012
maintenance of location GO:0051235 73 0.012
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
nucleosome organization GO:0034728 59 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
rna localization GO:0006403 115 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
rna processing GO:0006396 147 0.012
male mating behavior GO:0060179 70 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
aging GO:0007568 143 0.012
response to glucose GO:0009749 2 0.012
autophagic cell death GO:0048102 83 0.012
Fly
toxin metabolic process GO:0009404 2 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
developmental programmed cell death GO:0010623 138 0.012
Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
regulation of protein serine threonine kinase activity GO:0071900 25 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
amine metabolic process GO:0009308 12 0.011
kidney development GO:0001822 3 0.011
regulation of nervous system development GO:0051960 248 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
axonogenesis GO:0007409 290 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
nucleobase containing compound transport GO:0015931 56 0.011
phospholipid metabolic process GO:0006644 23 0.011
metal ion homeostasis GO:0055065 44 0.011
spindle elongation GO:0051231 83 0.011
nucleus organization GO:0006997 45 0.011
Fly
peripheral nervous system development GO:0007422 52 0.011
protein polymerization GO:0051258 42 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
covalent chromatin modification GO:0016569 106 0.011
alcohol catabolic process GO:0046164 4 0.011
microtubule bundle formation GO:0001578 27 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
aromatic compound catabolic process GO:0019439 166 0.010
regulation of programmed cell death GO:0043067 152 0.010
response to oxygen levels GO:0070482 59 0.010
positive regulation of cell cycle GO:0045787 43 0.010
regulation of response to external stimulus GO:0032101 115 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
response to other organism GO:0051707 293 0.010
regulation of immune response GO:0050776 118 0.010
cholesterol homeostasis GO:0042632 3 0.010
xenobiotic catabolic process GO:0042178 1 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
regulation of endopeptidase activity GO:0052548 36 0.010
rna splicing GO:0008380 83 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
transmembrane transport GO:0055085 139 0.010

Cdlc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
diabetes mellitus DOID:9351 0 0.016
disease of metabolism DOID:0014667 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.016
glucose metabolism disease DOID:4194 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012