Drosophila melanogaster

50 known processes

Lk6 (Dmel_CG17342)

CG17342 gene product from transcript CG17342-RA

(Aliases: CG6929,Dmel\CG17342,CG17342,lk6,anon-WO0172774.84,LK6,MNK/LK6,MESR8)

Lk6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular biosynthetic process GO:0031328 316 0.720
acylglycerol biosynthetic process GO:0046463 2 0.682
positive regulation of gene expression GO:0010628 290 0.620
response to nutrient levels GO:0031667 114 0.559
cellular response to external stimulus GO:0071496 66 0.510
positive regulation of biosynthetic process GO:0009891 316 0.506
response to extracellular stimulus GO:0009991 116 0.497
positive regulation of rna biosynthetic process GO:1902680 266 0.480
response to starvation GO:0042594 97 0.477
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.449
translation GO:0006412 69 0.400
Rat
positive regulation of insulin receptor signaling pathway GO:0046628 3 0.395
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.384
determination of adult lifespan GO:0008340 137 0.370
positive regulation of transcription dna templated GO:0045893 266 0.349
negative regulation of gene expression GO:0010629 387 0.336
regulation of response to stress GO:0080134 200 0.327
fatty acid homeostasis GO:0055089 2 0.319
transcription from rna polymerase ii promoter GO:0006366 368 0.289
response to abiotic stimulus GO:0009628 341 0.285
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.261
positive regulation of rna metabolic process GO:0051254 271 0.257
embryo development ending in birth or egg hatching GO:0009792 152 0.245
larval development GO:0002164 104 0.243
anion homeostasis GO:0055081 3 0.242
apoptotic process GO:0006915 159 0.238
Mouse
tor signaling GO:0031929 32 0.233
homeostatic process GO:0042592 199 0.223
multicellular organismal aging GO:0010259 140 0.216
intracellular signal transduction GO:0035556 300 0.211
aging GO:0007568 143 0.201
posttranscriptional regulation of gene expression GO:0010608 145 0.184
Rat
negative regulation of cellular metabolic process GO:0031324 382 0.183
regulation of multicellular organism growth GO:0040014 40 0.168
cellular response to extracellular stimulus GO:0031668 64 0.166
gene silencing by rna GO:0031047 57 0.160
positive regulation of macromolecule metabolic process GO:0010604 405 0.156
chromatin modification GO:0016568 147 0.154
secondary metabolite biosynthetic process GO:0044550 24 0.152
positive regulation of response to stimulus GO:0048584 323 0.149
cellular response to starvation GO:0009267 61 0.136
macroautophagy GO:0016236 42 0.124
programmed cell death GO:0012501 257 0.122
Mouse
oxoacid metabolic process GO:0043436 103 0.122
response to hypoxia GO:0001666 53 0.118
transmembrane transport GO:0055085 139 0.110
regulation of cellular response to insulin stimulus GO:1900076 17 0.107
autophagy GO:0006914 108 0.106
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.106
lateral inhibition GO:0046331 206 0.103
apoptotic signaling pathway GO:0097190 27 0.102
Mouse
regulation of response to external stimulus GO:0032101 115 0.099
regulation of response to extracellular stimulus GO:0032104 18 0.099
innate immune response GO:0045087 144 0.097
cell proliferation GO:0008283 299 0.096
compound eye morphogenesis GO:0001745 249 0.094
neutral lipid biosynthetic process GO:0046460 2 0.092
cellular macromolecule catabolic process GO:0044265 136 0.091
chromatin organization GO:0006325 207 0.089
negative regulation of cellular biosynthetic process GO:0031327 277 0.089
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.088
regulation of defense response GO:0031347 102 0.088
oxidation reduction process GO:0055114 123 0.088
gene silencing GO:0016458 138 0.086
negative regulation of cell communication GO:0010648 223 0.085
chemical homeostasis GO:0048878 92 0.083
cell cycle phase transition GO:0044770 140 0.083
regulation of cellular component biogenesis GO:0044087 201 0.080
defense response GO:0006952 300 0.077
triglyceride biosynthetic process GO:0019432 2 0.077
positive regulation of lipid catabolic process GO:0050996 1 0.077
posttranscriptional gene silencing GO:0016441 46 0.077
negative regulation of cell cycle process GO:0010948 109 0.077
skeletal muscle adaptation GO:0043501 1 0.076
maintenance of location GO:0051235 73 0.072
striated muscle adaptation GO:0014888 1 0.071
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.070
ion transmembrane transport GO:0034220 122 0.069
positive regulation of developmental process GO:0051094 143 0.069
positive regulation of lipid metabolic process GO:0045834 4 0.068
response to decreased oxygen levels GO:0036293 58 0.066
regulation of dna metabolic process GO:0051052 34 0.066
synaptic transmission GO:0007268 288 0.064
death GO:0016265 284 0.064
Mouse
regulation of phosphorylation GO:0042325 147 0.060
cellular catabolic process GO:0044248 372 0.060
response to organic substance GO:0010033 284 0.059
associative learning GO:0008306 65 0.058
posttranscriptional gene silencing by rna GO:0035194 45 0.058
positive regulation of growth GO:0045927 75 0.057
dna metabolic process GO:0006259 227 0.056
catabolic process GO:0009056 409 0.056
learning or memory GO:0007611 141 0.056
negative regulation of signaling GO:0023057 219 0.054
cellular response to oxygen levels GO:0071453 30 0.054
protein phosphorylation GO:0006468 169 0.054
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.053
regulation of cell growth GO:0001558 43 0.052
chromosome organization GO:0051276 360 0.051
metal ion homeostasis GO:0055065 44 0.051
immune system process GO:0002376 347 0.050
Human
positive regulation of protein metabolic process GO:0051247 128 0.050
mrna catabolic process GO:0006402 33 0.050
mitotic cell cycle phase transition GO:0044772 138 0.049
nucleobase containing compound catabolic process GO:0034655 165 0.049
lipid localization GO:0010876 54 0.049
regulation of cell cycle phase transition GO:1901987 130 0.049
phosphorylation GO:0016310 294 0.048
regulation of cell proliferation GO:0042127 163 0.048
cellular response to nutrient levels GO:0031669 62 0.045
regulation of cell death GO:0010941 173 0.044
response to oxygen levels GO:0070482 59 0.043
cellular response to sterol depletion GO:0071501 3 0.043
cellular response to dna damage stimulus GO:0006974 223 0.043
ion transport GO:0006811 145 0.043
response to temperature stimulus GO:0009266 106 0.041
organic substance catabolic process GO:1901575 308 0.041
regulation of immune system process GO:0002682 176 0.041
dendrite morphogenesis GO:0048813 199 0.041
mitotic dna integrity checkpoint GO:0044774 75 0.040
regulation of developmental growth GO:0048638 174 0.039
atp metabolic process GO:0046034 49 0.039
protein catabolic process GO:0030163 101 0.038
eye morphogenesis GO:0048592 260 0.037
developmental pigmentation GO:0048066 68 0.037
forebrain development GO:0030900 2 0.037
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.036
regulation of insulin receptor signaling pathway GO:0046626 17 0.036
growth GO:0040007 359 0.036
macromolecular complex assembly GO:0065003 256 0.036
brain development GO:0007420 120 0.036
purine nucleoside monophosphate catabolic process GO:0009128 38 0.036
regulation of mitotic cell cycle GO:0007346 190 0.035
positive regulation of signaling GO:0023056 243 0.035
macromolecule catabolic process GO:0009057 161 0.034
negative regulation of autophagy GO:0010507 16 0.034
positive regulation of lipid biosynthetic process GO:0046889 3 0.034
organic cyclic compound catabolic process GO:1901361 168 0.033
learning GO:0007612 75 0.033
regulation of cellular protein metabolic process GO:0032268 243 0.032
Rat
cellular carbohydrate metabolic process GO:0044262 22 0.032
regulation of cellular ketone metabolic process GO:0010565 3 0.032
regulation of response to nutrient levels GO:0032107 18 0.031
establishment or maintenance of cell polarity GO:0007163 167 0.031
acyl coa metabolic process GO:0006637 3 0.031
gene silencing by mirna GO:0035195 22 0.030
mrna metabolic process GO:0016071 124 0.030
cellular protein modification process GO:0006464 438 0.030
rna catabolic process GO:0006401 37 0.030
small molecule metabolic process GO:0044281 305 0.029
mitotic dna damage checkpoint GO:0044773 74 0.029
mitotic cell cycle checkpoint GO:0007093 88 0.029
regulation of autophagy GO:0010506 62 0.029
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
positive regulation of phosphorylation GO:0042327 87 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
regulation of apoptotic process GO:0042981 130 0.027
response to external biotic stimulus GO:0043207 293 0.027
regulation of response to oxidative stress GO:1902882 4 0.027
response to endoplasmic reticulum stress GO:0034976 28 0.027
regulation of cellular carbohydrate metabolic process GO:0010675 7 0.027
positive regulation of organelle organization GO:0010638 65 0.027
spindle organization GO:0007051 253 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
cellular response to chemical stimulus GO:0070887 199 0.026
Human
atp catabolic process GO:0006200 38 0.026
activation of protein kinase activity GO:0032147 12 0.026
positive regulation of cell size GO:0045793 21 0.026
regulation of transport GO:0051049 181 0.026
heterocycle catabolic process GO:0046700 166 0.026
regulation of macroautophagy GO:0016241 15 0.026
response to heat GO:0009408 63 0.026
dendrite development GO:0016358 204 0.025
negative regulation of cell cycle phase transition GO:1901988 103 0.025
regulation of cell size GO:0008361 63 0.025
positive regulation of developmental growth GO:0048639 62 0.025
positive regulation of signal transduction GO:0009967 223 0.025
regulation of intracellular signal transduction GO:1902531 236 0.024
aromatic compound catabolic process GO:0019439 166 0.024
regulation of organelle organization GO:0033043 196 0.024
stem cell differentiation GO:0048863 117 0.024
protein complex biogenesis GO:0070271 201 0.024
negative regulation of mitotic cell cycle GO:0045930 109 0.024
monocarboxylic acid metabolic process GO:0032787 29 0.023
negative regulation of neurogenesis GO:0050768 53 0.023
imaginal disc growth GO:0007446 37 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
negative regulation of cellular response to oxidative stress GO:1900408 1 0.022
response to organic cyclic compound GO:0014070 89 0.022
carbohydrate metabolic process GO:0005975 82 0.022
positive regulation of multicellular organism growth GO:0040018 21 0.022
response to light stimulus GO:0009416 124 0.022
regulation of translation GO:0006417 56 0.022
Rat
response to hexose GO:0009746 3 0.022
jak stat cascade GO:0007259 49 0.022
response to monosaccharide GO:0034284 4 0.021
organic acid metabolic process GO:0006082 103 0.021
compound eye development GO:0048749 307 0.021
central nervous system development GO:0007417 201 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
cognition GO:0050890 141 0.021
endocytosis GO:0006897 310 0.021
cellular response to peptide GO:1901653 28 0.020
negative regulation of response to oxidative stress GO:1902883 1 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.020
taxis GO:0042330 304 0.020
dna integrity checkpoint GO:0031570 81 0.020
molting cycle chitin based cuticle GO:0007591 56 0.020
multi organism reproductive behavior GO:0044705 121 0.020
peptidyl threonine phosphorylation GO:0018107 2 0.020
adult behavior GO:0030534 137 0.020
chromosome segregation GO:0007059 157 0.020
lipid homeostasis GO:0055088 33 0.019
telomere organization GO:0032200 21 0.019
cellular ketone metabolic process GO:0042180 24 0.019
meiotic chromosome segregation GO:0045132 59 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
single organism behavior GO:0044708 391 0.019
microtubule based transport GO:0010970 42 0.019
telomere maintenance GO:0000723 21 0.019
neuron projection guidance GO:0097485 241 0.018
negative regulation of intracellular signal transduction GO:1902532 57 0.018
rna processing GO:0006396 147 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
heterochromatin organization GO:0070828 25 0.018
histone modification GO:0016570 106 0.018
regulation of growth GO:0040008 233 0.017
positive regulation of kinase activity GO:0033674 25 0.017
eye development GO:0001654 323 0.017
positive regulation of cell communication GO:0010647 250 0.017
germ line stem cell maintenance GO:0030718 50 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
regulation of programmed cell death GO:0043067 152 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.017
cell death GO:0008219 279 0.016
Mouse
regulation of imaginal disc growth GO:0045570 26 0.016
vesicle mediated transport GO:0016192 381 0.016
chemotaxis GO:0006935 249 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
regulation of tor signaling GO:0032006 21 0.016
axon cargo transport GO:0008088 29 0.016
olfactory learning GO:0008355 56 0.016
regulation of protein phosphorylation GO:0001932 64 0.015
lipid metabolic process GO:0006629 121 0.015
regulation of mitochondrial fusion GO:0010635 5 0.015
regulation of cellular response to hypoxia GO:1900037 3 0.015
regulation of ion transport GO:0043269 39 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
metal ion transport GO:0030001 74 0.015
regulation of cell cycle GO:0051726 291 0.015
regulation of mitochondrial fission GO:0090140 7 0.014
regulation of nervous system development GO:0051960 248 0.014
autophagic vacuole fusion GO:0000046 15 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of membrane potential GO:0042391 35 0.014
primary spermatocyte growth GO:0007285 5 0.014
reproductive behavior GO:0019098 122 0.014
organelle membrane fusion GO:0090174 16 0.014
negative regulation of tor signaling GO:0032007 5 0.014
cellular response to organic substance GO:0071310 132 0.014
histone h4 k16 acetylation GO:0043984 4 0.014
response to oxidative stress GO:0006979 86 0.013
regulation of synaptic transmission GO:0050804 69 0.013
positive regulation of protein phosphorylation GO:0001934 34 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
single organism membrane budding GO:1902591 2 0.013
response to uv GO:0009411 24 0.013
response to oxygen containing compound GO:1901700 200 0.013
sex differentiation GO:0007548 81 0.013
covalent chromatin modification GO:0016569 106 0.013
cytoskeleton dependent intracellular transport GO:0030705 44 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
endomembrane system organization GO:0010256 119 0.013
dna damage checkpoint GO:0000077 78 0.012
ncrna metabolic process GO:0034660 43 0.012
long term memory GO:0007616 62 0.012
female meiotic division GO:0007143 70 0.012
response to peptide GO:1901652 29 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
somatic muscle development GO:0007525 66 0.012
insulin receptor signaling pathway GO:0008286 25 0.012
sperm mitochondrion organization GO:0030382 7 0.012
regulation of phosphatase activity GO:0010921 3 0.012
lipid storage GO:0019915 38 0.012
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of cellular response to oxidative stress GO:1900407 4 0.011
response to peptide hormone GO:0043434 29 0.011
regulation of jnk cascade GO:0046328 40 0.011
positive regulation of immune system process GO:0002684 68 0.011
single organism membrane organization GO:0044802 93 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
negative regulation of nervous system development GO:0051961 92 0.011
regulation of photoreceptor cell differentiation GO:0046532 34 0.011
cellular divalent inorganic cation homeostasis GO:0072503 23 0.011
locomotory behavior GO:0007626 176 0.011
regulation of cellular response to stress GO:0080135 89 0.011
regulation of neurogenesis GO:0050767 158 0.011
regulation of cell fate commitment GO:0010453 29 0.011
response to glucose GO:0009749 2 0.011
regulation of cell junction assembly GO:1901888 2 0.011
cation transport GO:0006812 110 0.011
protein localization GO:0008104 284 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
negative regulation of growth of symbiont involved in interaction with host GO:0044146 9 0.010
intrinsic apoptotic signaling pathway GO:0097193 16 0.010
response to metal ion GO:0010038 23 0.010
cellular response to hormone stimulus GO:0032870 44 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
hindbrain development GO:0030902 2 0.010

Lk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
acquired metabolic disease DOID:0060158 0 0.016