Drosophila melanogaster

84 known processes

drl (Dmel_CG17348)

derailed

(Aliases: Dmel\CG17348,CG10758,lin,lio,DRL,lio/drl,CG17348,Drl)

drl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron projection guidance GO:0097485 241 0.999
axon guidance GO:0007411 233 0.998
mushroom body development GO:0016319 70 0.991
brain development GO:0007420 120 0.989
Mouse
head development GO:0060322 135 0.987
Mouse
regulation of axon extension involved in axon guidance GO:0048841 4 0.985
Mouse
motor neuron axon guidance GO:0008045 58 0.983
Fly
chemotaxis GO:0006935 249 0.983
taxis GO:0042330 304 0.980
cell cell adhesion GO:0098609 26 0.974
central nervous system development GO:0007417 201 0.971
Mouse
axonogenesis GO:0007409 290 0.950
muscle structure development GO:0061061 224 0.939
central complex development GO:0048036 9 0.921
olfactory learning GO:0008355 56 0.905
single organism behavior GO:0044708 391 0.891
axon development GO:0061564 297 0.883
photoreceptor cell axon guidance GO:0072499 23 0.879
dendrite guidance GO:0070983 21 0.879
cell motility GO:0048870 251 0.878
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.871
Mouse
forebrain development GO:0030900 2 0.858
Mouse
axon choice point recognition GO:0016198 26 0.849
neurological system process GO:0050877 358 0.811
regulation of cell differentiation GO:0045595 302 0.798
Mouse
neuroblast proliferation GO:0007405 74 0.752
positive regulation of axonogenesis GO:0050772 2 0.749
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.680
neuroblast division GO:0055057 35 0.675
localization of cell GO:0051674 257 0.673
Zebrafish
gliogenesis GO:0042063 80 0.667
response to organic substance GO:0010033 284 0.620
axon midline choice point recognition GO:0016199 26 0.616
neuronal stem cell division GO:0036445 35 0.601
glial cell migration GO:0008347 31 0.585
homeostatic process GO:0042592 199 0.559
Zebrafish
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.541
eye development GO:0001654 323 0.533
regionalization GO:0003002 416 0.525
Worm
stem cell proliferation GO:0072089 88 0.516
ameboidal type cell migration GO:0001667 151 0.482
Zebrafish
appendage development GO:0048736 401 0.470
regulation of chemotaxis GO:0050920 12 0.452
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.443
regulation of protein metabolic process GO:0051246 256 0.438
regulation of anatomical structure morphogenesis GO:0022603 242 0.436
Mouse
morphogenesis of an epithelium GO:0002009 276 0.435
Zebrafish Worm
regulation of cell death GO:0010941 173 0.419
neuron projection extension GO:1990138 32 0.418
Mouse
protein localization GO:0008104 284 0.413
Worm
neural precursor cell proliferation GO:0061351 75 0.410
long term memory GO:0007616 62 0.408
somatic stem cell division GO:0048103 37 0.399
lateral inhibition GO:0046331 206 0.395
Fly
associative learning GO:0008306 65 0.385
dorsal ventral axon guidance GO:0033563 2 0.376
adult behavior GO:0030534 137 0.375
dendrite morphogenesis GO:0048813 199 0.365
dendrite development GO:0016358 204 0.364
cell adhesion GO:0007155 136 0.357
negative regulation of neural precursor cell proliferation GO:2000178 27 0.354
cell proliferation GO:0008283 299 0.352
response to ethanol GO:0045471 59 0.350
positive regulation of gene expression GO:0010628 290 0.348
post embryonic appendage morphogenesis GO:0035120 385 0.346
embryonic morphogenesis GO:0048598 206 0.325
Zebrafish
negative regulation of rna metabolic process GO:0051253 251 0.313
cognition GO:0050890 141 0.300
chemical homeostasis GO:0048878 92 0.299
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 35 0.297
positive regulation of cellular component organization GO:0051130 156 0.293
regulation of cell development GO:0060284 215 0.289
Mouse
epithelial cell development GO:0002064 274 0.288
formation of organ boundary GO:0010160 30 0.283
axis specification GO:0009798 167 0.280
Worm
neuron recognition GO:0008038 101 0.277
kidney development GO:0001822 3 0.266
response to alcohol GO:0097305 95 0.265
tissue migration GO:0090130 155 0.261
gland development GO:0048732 191 0.257
learning GO:0007612 75 0.257
response to oxygen containing compound GO:1901700 200 0.257
regulation of cellular component movement GO:0051270 42 0.255
Mouse
salivary gland development GO:0007431 162 0.253
cell cell signaling involved in cell fate commitment GO:0045168 210 0.246
Fly
cell division GO:0051301 248 0.242
Worm
biological adhesion GO:0022610 138 0.241
regulation of cellular amino acid metabolic process GO:0006521 0 0.241
phosphorylation GO:0016310 294 0.232
Human Fly
cell migration GO:0016477 238 0.228
Zebrafish
sensory perception of smell GO:0007608 80 0.226
developmental growth GO:0048589 280 0.224
Zebrafish Mouse
cell junction organization GO:0034330 57 0.221
epithelial cell differentiation GO:0030855 322 0.214
behavioral response to ethanol GO:0048149 49 0.212
single organism intracellular transport GO:1902582 207 0.209
Zebrafish
negative regulation of cell development GO:0010721 62 0.206
Mouse
peripheral nervous system development GO:0007422 52 0.205
telencephalon development GO:0021537 2 0.196
Mouse
regulation of cell morphogenesis GO:0022604 163 0.196
Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.196
Zebrafish Mouse
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.188
regulation of epithelial cell proliferation GO:0050678 4 0.185
regulation of epithelial cell migration GO:0010632 12 0.182
ventral cord development GO:0007419 16 0.181
camera type eye development GO:0043010 4 0.178
organonitrogen compound metabolic process GO:1901564 318 0.175
stem cell division GO:0017145 69 0.166
actin cytoskeleton organization GO:0030036 206 0.165
regulation of locomotion GO:0040012 42 0.165
Mouse
locomotory behavior GO:0007626 176 0.162
positive regulation of axon guidance GO:1902669 1 0.161
salivary gland boundary specification GO:0007432 8 0.159
regulation of cellular protein metabolic process GO:0032268 243 0.157
cellular response to chemical stimulus GO:0070887 199 0.157
imaginal disc derived appendage morphogenesis GO:0035114 395 0.153
single organismal cell cell adhesion GO:0016337 45 0.152
tissue morphogenesis GO:0048729 297 0.152
Zebrafish Worm
regulation of apoptotic process GO:0042981 130 0.143
growth GO:0040007 359 0.139
Zebrafish Mouse
regulation of cell cycle GO:0051726 291 0.138
olfactory bulb axon guidance GO:0071678 3 0.135
regulation of neuron differentiation GO:0045664 103 0.135
Mouse
muscle organ development GO:0007517 127 0.134
negative regulation of gene expression GO:0010629 387 0.134
regulation of cell migration GO:0030334 22 0.131
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.130
regulation of phosphorus metabolic process GO:0051174 210 0.127
Human
regulation of dendrite development GO:0050773 37 0.126
chromatin modification GO:0016568 147 0.123
cell death GO:0008219 279 0.121
positive regulation of axon extension GO:0045773 2 0.121
skeletal muscle organ development GO:0060538 48 0.121
single organism catabolic process GO:0044712 228 0.120
regulation of programmed cell death GO:0043067 152 0.120
compound eye photoreceptor cell differentiation GO:0001751 140 0.119
developmental cell growth GO:0048588 52 0.119
Mouse
actin filament based process GO:0030029 220 0.119
columnar cuboidal epithelial cell development GO:0002066 249 0.119
epithelial cell migration GO:0010631 148 0.115
negative regulation of neurogenesis GO:0050768 53 0.115
Mouse
negative regulation of epithelial cell proliferation GO:0050680 4 0.113
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.112
memory GO:0007613 94 0.112
chemosensory behavior GO:0007635 106 0.112
cellular response to organic substance GO:0071310 132 0.111
positive regulation of multicellular organismal process GO:0051240 143 0.110
regulation of behavior GO:0050795 75 0.110
Mouse
positive regulation of cell communication GO:0010647 250 0.110
Human
cellular chemical homeostasis GO:0055082 40 0.108
Zebrafish
digestive system development GO:0055123 149 0.108
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 405 0.105
cellular catabolic process GO:0044248 372 0.105
negative regulation of cellular metabolic process GO:0031324 382 0.103
positive regulation of rna metabolic process GO:0051254 271 0.102
negative regulation of multicellular organismal process GO:0051241 142 0.102
Mouse
chromatin organization GO:0006325 207 0.101
learning or memory GO:0007611 141 0.099
retinal ganglion cell axon guidance GO:0031290 12 0.098
anterior posterior axis specification GO:0009948 109 0.098
Worm
brain morphogenesis GO:0048854 16 0.097
epithelium migration GO:0090132 148 0.097
cell cell junction organization GO:0045216 55 0.096
regulation of response to external stimulus GO:0032101 115 0.096
Mouse
imaginal disc derived appendage development GO:0048737 399 0.095
axon extension GO:0048675 32 0.094
Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.090
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.087
response to abiotic stimulus GO:0009628 341 0.086
cellular amino acid metabolic process GO:0006520 61 0.084
muscle attachment GO:0016203 36 0.083
cell recognition GO:0008037 102 0.082
cellular macromolecule localization GO:0070727 220 0.082
eye photoreceptor cell differentiation GO:0001754 145 0.081
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.076
cell fate determination GO:0001709 91 0.076
Worm
positive regulation of signal transduction GO:0009967 223 0.075
Human
cell growth GO:0016049 108 0.075
Mouse
vesicle mediated transport GO:0016192 381 0.073
regulation of cell adhesion GO:0030155 27 0.073
sex differentiation GO:0007548 81 0.071
Worm
regulation of neuroblast proliferation GO:1902692 34 0.071
response to external biotic stimulus GO:0043207 293 0.071
positive regulation of nervous system development GO:0051962 69 0.068
regulation of axon guidance GO:1902667 10 0.067
Mouse
cellular homeostasis GO:0019725 80 0.067
Zebrafish
positive regulation of rna biosynthetic process GO:1902680 266 0.067
dna metabolic process GO:0006259 227 0.066
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.066
single organism biosynthetic process GO:0044711 206 0.065
protein maturation GO:0051604 71 0.065
cellular response to endogenous stimulus GO:0071495 80 0.065
regulation of cell proliferation GO:0042127 163 0.064
regulation of stem cell proliferation GO:0072091 40 0.064
regulation of multicellular organismal development GO:2000026 414 0.064
Mouse Worm
embryonic pattern specification GO:0009880 174 0.063
determination of muscle attachment site GO:0016204 7 0.063
positive regulation of transcription dna templated GO:0045893 266 0.062
organic acid metabolic process GO:0006082 103 0.062
single organism cell adhesion GO:0098602 47 0.062
asymmetric protein localization GO:0008105 33 0.061
Worm
programmed cell death GO:0012501 257 0.061
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.060
immune system process GO:0002376 347 0.058
positive regulation of response to stimulus GO:0048584 323 0.058
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.058
carboxylic acid metabolic process GO:0019752 92 0.058
positive regulation of cell migration GO:0030335 2 0.057
appendage morphogenesis GO:0035107 397 0.056
compound eye development GO:0048749 307 0.056
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.056
glandular epithelial cell differentiation GO:0002067 1 0.056
small molecule metabolic process GO:0044281 305 0.056
gland morphogenesis GO:0022612 145 0.056
extrinsic apoptotic signaling pathway GO:0097191 1 0.055
negative regulation of cellular component organization GO:0051129 108 0.055
Mouse
negative regulation of cell death GO:0060548 81 0.055
response to monosaccharide GO:0034284 4 0.054
nucleoside triphosphate metabolic process GO:0009141 120 0.054
formation of anatomical boundary GO:0048859 37 0.054
proteolysis GO:0006508 192 0.054
blastoderm segmentation GO:0007350 159 0.054
protein complex biogenesis GO:0070271 201 0.054
tube development GO:0035295 244 0.053
Zebrafish
digestive tract development GO:0048565 149 0.053
Zebrafish
male gamete generation GO:0048232 201 0.053
olfactory behavior GO:0042048 97 0.052
positive regulation of apoptotic signaling pathway GO:2001235 4 0.052
chromosome organization GO:0051276 360 0.051
regulation of cell division GO:0051302 72 0.051
Worm
response to glucose GO:0009749 2 0.051
negative regulation of signaling GO:0023057 219 0.051
regulation of cell cycle process GO:0010564 181 0.049
negative regulation of cell proliferation GO:0008285 69 0.049
organophosphate metabolic process GO:0019637 195 0.049
regulation of protein complex assembly GO:0043254 42 0.048
enteroendocrine cell differentiation GO:0035883 1 0.048
catabolic process GO:0009056 409 0.047
negative regulation of biosynthetic process GO:0009890 277 0.047
negative regulation of neuron differentiation GO:0045665 16 0.047
Mouse
oocyte axis specification GO:0007309 108 0.047
retina development in camera type eye GO:0060041 4 0.047
sensory organ morphogenesis GO:0090596 260 0.046
apoptotic signaling pathway GO:0097190 27 0.046
regulation of nervous system development GO:0051960 248 0.046
Mouse
regulation of developmental growth GO:0048638 174 0.045
Mouse
positive regulation of developmental process GO:0051094 143 0.045
cellular divalent inorganic cation homeostasis GO:0072503 23 0.045
Zebrafish
regulation of cell motility GO:2000145 23 0.045
regulation of catabolic process GO:0009894 170 0.045
organic substance catabolic process GO:1901575 308 0.045
purine containing compound catabolic process GO:0072523 112 0.044
regulation of phosphate metabolic process GO:0019220 210 0.044
Human
intracellular signal transduction GO:0035556 300 0.044
Human
purine nucleoside metabolic process GO:0042278 127 0.044
negative regulation of cell differentiation GO:0045596 143 0.043
Mouse
cellular amine metabolic process GO:0044106 12 0.043
eye photoreceptor cell fate commitment GO:0042706 37 0.043
negative regulation of axon extension GO:0030517 3 0.043
Mouse
dorsal ventral axis specification GO:0009950 66 0.043
compound eye morphogenesis GO:0001745 249 0.043
developmental maturation GO:0021700 172 0.043
death GO:0016265 284 0.042
photoreceptor cell differentiation GO:0046530 170 0.041
synapse assembly GO:0007416 143 0.041
photoreceptor cell fate commitment GO:0046552 41 0.040
regulation of cellular ketone metabolic process GO:0010565 3 0.040
endocrine system development GO:0035270 5 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.039
negative regulation of cell communication GO:0010648 223 0.039
cellular response to oxygen containing compound GO:1901701 79 0.039
ovarian follicle cell migration GO:0007297 121 0.039
determination of dorsal ventral asymmetry GO:0048262 3 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.038
regulation of response to stress GO:0080134 200 0.038
cellular component assembly involved in morphogenesis GO:0010927 151 0.037
positive regulation of cell motility GO:2000147 3 0.037
urogenital system development GO:0001655 72 0.037
negative regulation of nervous system development GO:0051961 92 0.037
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.037
Human
regulation of cellular catabolic process GO:0031329 157 0.036
purine containing compound metabolic process GO:0072521 155 0.036
reproductive structure development GO:0048608 74 0.036
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.036
positive regulation of cell differentiation GO:0045597 64 0.036
regulation of photoreceptor cell axon guidance GO:2000289 5 0.035
secretion GO:0046903 109 0.035
gastrulation GO:0007369 70 0.035
Zebrafish
kidney epithelium development GO:0072073 3 0.034
oxoacid metabolic process GO:0043436 103 0.034
regulation of neurogenesis GO:0050767 158 0.034
Mouse
regulation of molecular function GO:0065009 217 0.034
sensory perception GO:0007600 196 0.034
negative regulation of cellular biosynthetic process GO:0031327 277 0.034
positive regulation of cellular protein metabolic process GO:0032270 118 0.033
histone modification GO:0016570 106 0.033
protein modification process GO:0036211 438 0.033
Fly
ribose phosphate metabolic process GO:0019693 145 0.033
eye morphogenesis GO:0048592 260 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
synapse organization GO:0050808 196 0.032
segmentation GO:0035282 207 0.032
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.032
response to hexose GO:0009746 3 0.032
negative regulation of nucleic acid templated transcription GO:1903507 240 0.031
regulation of anatomical structure size GO:0090066 163 0.031
Mouse
regulation of organelle organization GO:0033043 196 0.031
cell migration involved in gastrulation GO:0042074 9 0.031
Zebrafish
regulation of protein modification process GO:0031399 112 0.030
regulation of photoreceptor cell differentiation GO:0046532 34 0.030
mesenchymal cell development GO:0014031 1 0.030
camera type eye photoreceptor cell differentiation GO:0060219 2 0.030
regulation of axonogenesis GO:0050770 32 0.030
Mouse
axonal fasciculation GO:0007413 12 0.029
cardiovascular system development GO:0072358 82 0.029
cell projection assembly GO:0030031 94 0.029
cell maturation GO:0048469 144 0.029
central nervous system projection neuron axonogenesis GO:0021952 6 0.028
regulation of phosphorylation GO:0042325 147 0.028
Human
outflow tract morphogenesis GO:0003151 4 0.028
regulation of growth GO:0040008 233 0.028
Mouse
negative regulation of neuroblast proliferation GO:0007406 27 0.028
regulation of axon extension GO:0030516 8 0.028
Mouse
regulation of multi organism process GO:0043900 131 0.028
hindbrain development GO:0030902 2 0.027
nucleoside metabolic process GO:0009116 127 0.027
asymmetric stem cell division GO:0098722 49 0.027
negative regulation of cell cycle GO:0045786 116 0.027
regulation of neuron projection development GO:0010975 69 0.026
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.026
glycosyl compound catabolic process GO:1901658 112 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
Human
inositol lipid mediated signaling GO:0048017 4 0.026
regulation of actin filament based process GO:0032970 42 0.026
neuron fate commitment GO:0048663 50 0.026
regulation of cell matrix adhesion GO:0001952 1 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
positive regulation of catabolic process GO:0009896 105 0.025
response to sterol GO:0036314 34 0.025
neuron migration GO:0001764 5 0.025
maintenance of location GO:0051235 73 0.025
Zebrafish
dorsal ventral pattern formation GO:0009953 133 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
negative regulation of apoptotic process GO:0043066 63 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.025
reproductive system development GO:0061458 74 0.025
Worm
transcription from rna polymerase ii promoter GO:0006366 368 0.024
protein processing GO:0016485 68 0.024
regulation of extent of cell growth GO:0061387 8 0.024
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 27 0.024
syncytium formation by plasma membrane fusion GO:0000768 43 0.024
regulation of cell projection organization GO:0031344 92 0.024
Mouse
spinal cord development GO:0021510 1 0.024
positive regulation of immune system process GO:0002684 68 0.024
regulation of cellular component size GO:0032535 98 0.024
Mouse
negative regulation of programmed cell death GO:0043069 72 0.024
regulation of cell size GO:0008361 63 0.023
Mouse
spermatogenesis GO:0007283 200 0.023
exocrine system development GO:0035272 162 0.023
regulation of immune system process GO:0002682 176 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
divalent inorganic cation homeostasis GO:0072507 29 0.023
Zebrafish
covalent chromatin modification GO:0016569 106 0.023
renal system development GO:0072001 72 0.023
glial cell development GO:0021782 27 0.023
protein catabolic process GO:0030163 101 0.023
lamellipodium organization GO:0097581 21 0.022
stem cell development GO:0048864 79 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
negative regulation of catalytic activity GO:0043086 42 0.022
positive regulation of neuron projection development GO:0010976 14 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
embryonic axis specification GO:0000578 107 0.022
body morphogenesis GO:0010171 2 0.021
positive chemotaxis GO:0050918 4 0.021
positive regulation of developmental growth GO:0048639 62 0.021
synaptic target recognition GO:0008039 45 0.021
Fly
photoreceptor cell development GO:0042461 96 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
negative regulation of growth GO:0045926 84 0.020
Mouse
salivary gland morphogenesis GO:0007435 145 0.020
regulation of cell substrate adhesion GO:0010810 2 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
compound eye photoreceptor development GO:0042051 78 0.019
branching morphogenesis of an epithelial tube GO:0048754 45 0.019
neuroblast development GO:0014019 13 0.019
actin polymerization or depolymerization GO:0008154 31 0.019
protein phosphorylation GO:0006468 169 0.019
Fly
macromolecular complex assembly GO:0065003 256 0.019
dendrite self avoidance GO:0070593 8 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
protein localization to organelle GO:0033365 82 0.018
retinal cone cell differentiation GO:0042670 2 0.018
organic hydroxy compound biosynthetic process GO:1901617 21 0.018
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.018
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.018
Mouse
regulation of localization GO:0032879 275 0.018
Zebrafish Mouse
response to lipopolysaccharide GO:0032496 4 0.017
immune response regulating signaling pathway GO:0002764 2 0.017
single organism cellular localization GO:1902580 180 0.017
regulation of proteolysis GO:0030162 87 0.017
positive regulation of signaling GO:0023056 243 0.017
Human
regulation of protein localization GO:0032880 76 0.017
gastrulation involving germ band extension GO:0010004 36 0.017
endocytosis GO:0006897 310 0.017
circadian rhythm GO:0007623 105 0.017
negative regulation of developmental process GO:0051093 201 0.017
Mouse
cell matrix adhesion GO:0007160 6 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
positive regulation of cell cycle process GO:0090068 28 0.016
nephron epithelium development GO:0072009 3 0.016
stem cell differentiation GO:0048863 117 0.016
anterior commissure morphogenesis GO:0021960 2 0.016
macromolecule catabolic process GO:0009057 161 0.016
nephron development GO:0072006 3 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
apoptotic process GO:0006915 159 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
asymmetric cell division GO:0008356 37 0.015
Worm
response to other organism GO:0051707 293 0.015
skeletal muscle fiber development GO:0048741 3 0.015
glial cell differentiation GO:0010001 35 0.015
nucleotide catabolic process GO:0009166 109 0.015
regulation of immune response GO:0050776 118 0.015
cellular cation homeostasis GO:0030003 38 0.015
Zebrafish
regulation of nucleoside metabolic process GO:0009118 50 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
negative regulation of stem cell proliferation GO:2000647 30 0.015
positive regulation of cell cycle GO:0045787 43 0.015
adherens junction organization GO:0034332 27 0.015
negative regulation of response to external stimulus GO:0032102 22 0.015
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
spindle localization GO:0051653 22 0.015
positive regulation of cell death GO:0010942 69 0.014
cellular response to organic cyclic compound GO:0071407 32 0.014
r7 cell differentiation GO:0045466 43 0.014
development of primary female sexual characteristics GO:0046545 12 0.014
cellular protein modification process GO:0006464 438 0.014
Fly
response to organonitrogen compound GO:0010243 75 0.014
compound eye photoreceptor fate commitment GO:0001752 36 0.014
protein complex assembly GO:0006461 200 0.014
regulation of rac protein signal transduction GO:0035020 3 0.014
actin filament organization GO:0007015 126 0.014
positive regulation of locomotion GO:0040017 8 0.014
epithelial tube morphogenesis GO:0060562 88 0.014
organ formation GO:0048645 39 0.014
gonad morphogenesis GO:0035262 7 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
organelle fission GO:0048285 340 0.014
establishment of spindle orientation GO:0051294 18 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
Human
cell type specific apoptotic process GO:0097285 38 0.013
nephron morphogenesis GO:0072028 3 0.013
cytoplasmic transport GO:0016482 130 0.013
Zebrafish
positive regulation of stem cell proliferation GO:2000648 8 0.013
regulation of tube size open tracheal system GO:0035151 43 0.013
pole plasm mrna localization GO:0019094 49 0.013
response to nitrogen compound GO:1901698 90 0.013
regulation of protein phosphorylation GO:0001932 64 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
Human
positive regulation of neurogenesis GO:0050769 41 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
sensory perception of mechanical stimulus GO:0050954 72 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
nephron tubule morphogenesis GO:0072078 3 0.013
convergent extension GO:0060026 2 0.013
Zebrafish
response to organic cyclic compound GO:0014070 89 0.013
purine nucleotide catabolic process GO:0006195 109 0.012
sensory perception of chemical stimulus GO:0007606 116 0.012
positive regulation of cell projection organization GO:0031346 29 0.012
phosphatidylinositol mediated signaling GO:0048015 4 0.012
regulation of hydrolase activity GO:0051336 97 0.012
negative regulation of developmental growth GO:0048640 64 0.012
Mouse
embryonic organ development GO:0048568 50 0.012
cell cell adhesion mediated by cadherin GO:0044331 6 0.012
positive regulation of cell development GO:0010720 61 0.012
establishment of localization in cell GO:0051649 402 0.012
Zebrafish
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
kidney morphogenesis GO:0060993 3 0.012
response to biotic stimulus GO:0009607 294 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
phagocytosis GO:0006909 215 0.012
ocellus development GO:0008056 4 0.012
apical constriction GO:0003383 18 0.012

drl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.218
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
nervous system disease DOID:863 0 0.016
eye disease DOID:5614 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
cardiovascular system disease DOID:1287 0 0.013
organ system cancer DOID:0050686 0 0.012