Drosophila melanogaster

0 known processes

sec71 (Dmel_CG7578)

CG7578 gene product from transcript CG7578-RA

(Aliases: BG:DS00797.7,Dmel\CG7578,BIG1,CG7578)

sec71 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endomembrane system organization GO:0010256 119 0.152
Human
vesicle mediated transport GO:0016192 381 0.139
Human Rat
male gamete generation GO:0048232 201 0.138
epithelial cell differentiation GO:0030855 322 0.097
establishment of localization in cell GO:0051649 402 0.081
Human Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.080
Human
spermatogenesis GO:0007283 200 0.072
carbohydrate derivative metabolic process GO:1901135 217 0.072
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.064
Human
nucleotide catabolic process GO:0009166 109 0.062
Human
homeostatic process GO:0042592 199 0.062
nucleoside catabolic process GO:0009164 112 0.061
Human
organonitrogen compound metabolic process GO:1901564 318 0.060
Human
single organism behavior GO:0044708 391 0.057
microtubule based movement GO:0007018 51 0.056
positive regulation of catabolic process GO:0009896 105 0.052
Human
nucleobase containing compound catabolic process GO:0034655 165 0.052
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.049
Human
macromolecular complex assembly GO:0065003 256 0.048
vesicle organization GO:0016050 44 0.048
protein catabolic process GO:0030163 101 0.047
nucleoside triphosphate metabolic process GO:0009141 120 0.046
Human
purine containing compound metabolic process GO:0072521 155 0.045
Human
regulation of small gtpase mediated signal transduction GO:0051056 93 0.045
positive regulation of cellular catabolic process GO:0031331 95 0.044
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.044
Human
carbohydrate derivative catabolic process GO:1901136 118 0.044
Human
protein localization GO:0008104 284 0.043
positive regulation of hydrolase activity GO:0051345 78 0.043
Human
gtp metabolic process GO:0046039 72 0.042
Human
ribonucleotide metabolic process GO:0009259 145 0.042
Human
cell projection assembly GO:0030031 94 0.041
macromolecule catabolic process GO:0009057 161 0.040
guanosine containing compound metabolic process GO:1901068 74 0.039
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.039
positive regulation of phosphate metabolic process GO:0045937 139 0.039
Human
innate immune response GO:0045087 144 0.039
organic substance catabolic process GO:1901575 308 0.038
Human
secretion GO:0046903 109 0.038
Rat
purine ribonucleoside metabolic process GO:0046128 127 0.038
Human
ribonucleoside catabolic process GO:0042454 112 0.038
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.038
Human
purine ribonucleoside catabolic process GO:0046130 112 0.038
Human
organic cyclic compound catabolic process GO:1901361 168 0.037
Human
kidney epithelium development GO:0072073 3 0.037
ras protein signal transduction GO:0007265 88 0.037
organophosphate catabolic process GO:0046434 112 0.037
Human
purine containing compound catabolic process GO:0072523 112 0.037
Human
protein complex assembly GO:0006461 200 0.037
catabolic process GO:0009056 409 0.036
Human
ribonucleotide catabolic process GO:0009261 109 0.036
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.036
Human
purine nucleoside metabolic process GO:0042278 127 0.036
Human
chemical homeostasis GO:0048878 92 0.036
positive regulation of biosynthetic process GO:0009891 316 0.036
regulation of molecular function GO:0065009 217 0.035
Human
purine ribonucleotide catabolic process GO:0009154 109 0.035
Human
regulation of transport GO:0051049 181 0.034
columnar cuboidal epithelial cell development GO:0002066 249 0.034
regulation of localization GO:0032879 275 0.034
cellular protein catabolic process GO:0044257 83 0.034
small gtpase mediated signal transduction GO:0007264 88 0.034
modification dependent macromolecule catabolic process GO:0043632 79 0.034
epithelial cell development GO:0002064 274 0.033
cellular macromolecule catabolic process GO:0044265 136 0.033
modification dependent protein catabolic process GO:0019941 78 0.033
nucleoside phosphate catabolic process GO:1901292 110 0.033
Human
regulation of purine nucleotide catabolic process GO:0033121 48 0.033
Human
positive regulation of nucleoside metabolic process GO:0045979 47 0.032
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.032
Human
glycosyl compound catabolic process GO:1901658 112 0.032
Human
regulation of cell cycle phase transition GO:1901987 130 0.031
cellular catabolic process GO:0044248 372 0.031
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
growth GO:0040007 359 0.030
cellular homeostasis GO:0019725 80 0.030
hindbrain development GO:0030902 2 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.030
Human
protein modification by small protein conjugation or removal GO:0070647 106 0.030
regulation of nucleotide metabolic process GO:0006140 62 0.030
Human
regionalization GO:0003002 416 0.030
actin cytoskeleton organization GO:0030036 206 0.030
cell motility GO:0048870 251 0.030
protein complex biogenesis GO:0070271 201 0.030
axon cargo transport GO:0008088 29 0.029
regulation of gtp catabolic process GO:0033124 44 0.029
Human
organonitrogen compound catabolic process GO:1901565 128 0.029
Human
immune system process GO:0002376 347 0.029
regulation of cell differentiation GO:0045595 302 0.028
purine nucleoside triphosphate catabolic process GO:0009146 108 0.028
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.028
cellularization GO:0007349 90 0.028
ubiquitin dependent protein catabolic process GO:0006511 78 0.028
regulation of immune response GO:0050776 118 0.027
endocytosis GO:0006897 310 0.027
single organism intracellular transport GO:1902582 207 0.027
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.027
ameboidal type cell migration GO:0001667 151 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.026
Human
regulation of cellular component biogenesis GO:0044087 201 0.026
body morphogenesis GO:0010171 2 0.026
ribose phosphate metabolic process GO:0019693 145 0.026
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.026
Human
heterocycle catabolic process GO:0046700 166 0.026
Human
embryonic axis specification GO:0000578 107 0.026
phagocytosis GO:0006909 215 0.026
microtubule based transport GO:0010970 42 0.026
positive regulation of nucleotide metabolic process GO:0045981 55 0.025
Human
immune response GO:0006955 246 0.025
cell migration GO:0016477 238 0.025
single organism biosynthetic process GO:0044711 206 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
regulation of ras protein signal transduction GO:0046578 93 0.025
appendage development GO:0048736 401 0.025
positive regulation of gtpase activity GO:0043547 43 0.025
Human
single organism membrane organization GO:0044802 93 0.025
tube morphogenesis GO:0035239 191 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
aromatic compound catabolic process GO:0019439 166 0.024
Human
anterior posterior pattern specification GO:0009952 136 0.024
cellular amine metabolic process GO:0044106 12 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
morphogenesis of an epithelium GO:0002009 276 0.024
embryonic morphogenesis GO:0048598 206 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
purine nucleotide catabolic process GO:0006195 109 0.023
Human
synaptic transmission GO:0007268 288 0.023
developmental maturation GO:0021700 172 0.023
protein transport GO:0015031 155 0.023
protein modification by small protein conjugation GO:0032446 79 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
Human
dna metabolic process GO:0006259 227 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
synaptic vesicle transport GO:0048489 50 0.023
cytoskeleton dependent cytokinesis GO:0061640 81 0.022
positive regulation of developmental process GO:0051094 143 0.022
intracellular signal transduction GO:0035556 300 0.022
Human
detection of stimulus involved in sensory perception GO:0050906 92 0.022
regulation of hydrolase activity GO:0051336 97 0.022
Human
ovarian follicle cell development GO:0030707 248 0.022
positive regulation of gtp catabolic process GO:0033126 43 0.022
Human
digestive system development GO:0055123 149 0.022
single organism cellular localization GO:1902580 180 0.022
skin development GO:0043588 65 0.021
regulation of epithelial cell differentiation GO:0030856 4 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
Human
regulation of catalytic activity GO:0050790 185 0.021
Human
secondary metabolic process GO:0019748 75 0.021
protein modification process GO:0036211 438 0.021
single organism catabolic process GO:0044712 228 0.021
Human
proteolysis GO:0006508 192 0.021
centrosome organization GO:0051297 163 0.021
immune effector process GO:0002252 98 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
cellular metal ion homeostasis GO:0006875 31 0.020
establishment of organelle localization GO:0051656 122 0.020
guanosine containing compound catabolic process GO:1901069 74 0.020
Human
golgi organization GO:0007030 66 0.020
organic substance transport GO:0071702 257 0.020
gtp catabolic process GO:0006184 72 0.020
Human
positive regulation of immune system process GO:0002684 68 0.020
regulation of catabolic process GO:0009894 170 0.020
Human
compound eye photoreceptor cell differentiation GO:0001751 140 0.020
intracellular transport GO:0046907 228 0.020
Human
regulation of nucleotide catabolic process GO:0030811 48 0.020
Human
regulation of immune system process GO:0002682 176 0.020
positive regulation of molecular function GO:0044093 136 0.019
Human
dorsal ventral pattern formation GO:0009953 133 0.019
response to external biotic stimulus GO:0043207 293 0.019
organelle localization GO:0051640 148 0.019
secretion by cell GO:0032940 101 0.019
Rat
positive regulation of ras gtpase activity GO:0032320 36 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
Human
developmental pigmentation GO:0048066 68 0.019
microtubule organizing center organization GO:0031023 168 0.019
metal ion homeostasis GO:0055065 44 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
Human
anterior posterior axis specification GO:0009948 109 0.018
thioester metabolic process GO:0035383 3 0.018
tissue morphogenesis GO:0048729 297 0.018
regulation of cell proliferation GO:0042127 163 0.018
regulation of defense response GO:0031347 102 0.018
nucleotide metabolic process GO:0009117 161 0.018
Human
regulation of cell adhesion GO:0030155 27 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
Human
regulation of ras gtpase activity GO:0032318 38 0.018
cytoskeleton dependent intracellular transport GO:0030705 44 0.018
regulation of protein localization GO:0032880 76 0.018
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
respiratory system development GO:0060541 213 0.017
lateral inhibition GO:0046331 206 0.017
positive regulation of nervous system development GO:0051962 69 0.017
compound eye development GO:0048749 307 0.017
nephron development GO:0072006 3 0.017
synaptic vesicle endocytosis GO:0048488 28 0.017
exocrine system development GO:0035272 162 0.017
compound eye morphogenesis GO:0001745 249 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
epidermal growth factor receptor signaling pathway GO:0007173 58 0.017
protein secretion GO:0009306 45 0.017
positive regulation of transport GO:0051050 92 0.017
cell growth GO:0016049 108 0.017
regulation of growth GO:0040008 233 0.017
ribonucleoside metabolic process GO:0009119 127 0.016
Human
positive regulation of nucleotide catabolic process GO:0030813 46 0.016
Human
positive regulation of multicellular organismal process GO:0051240 143 0.016
Human
golgi vesicle transport GO:0048193 27 0.016
Human
pigmentation GO:0043473 75 0.016
cholesterol homeostasis GO:0042632 3 0.016
establishment of protein localization GO:0045184 163 0.016
erbb signaling pathway GO:0038127 58 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
Human
regulation of cellular localization GO:0060341 136 0.016
cellular protein localization GO:0034613 160 0.016
positive regulation of secretion GO:0051047 22 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
cellular protein modification process GO:0006464 438 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
regulation of immune effector process GO:0002697 52 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
golgi localization GO:0051645 2 0.015
positive regulation of organelle organization GO:0010638 65 0.015
establishment of synaptic vesicle localization GO:0097480 50 0.015
mitotic nuclear division GO:0007067 213 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
negative regulation of immune system process GO:0002683 50 0.015
positive regulation of dendrite morphogenesis GO:0050775 9 0.015
positive regulation of calcium ion transport GO:0051928 4 0.015
blastoderm segmentation GO:0007350 159 0.015
cell proliferation GO:0008283 299 0.014
endoplasmic reticulum organization GO:0007029 13 0.014
ion homeostasis GO:0050801 55 0.014
regulation of embryonic development GO:0045995 68 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
tripartite regional subdivision GO:0007351 103 0.014
response to bacterium GO:0009617 198 0.014
locomotory behavior GO:0007626 176 0.014
defense response to other organism GO:0098542 225 0.014
cell fate determination GO:0001709 91 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
eye development GO:0001654 323 0.014
eye morphogenesis GO:0048592 260 0.014
actin filament based process GO:0030029 220 0.014
epithelial cell migration GO:0010631 148 0.014
maternal determination of anterior posterior axis embryo GO:0008358 74 0.014
defense response to bacterium GO:0042742 178 0.014
chemotaxis GO:0006935 249 0.013
cation homeostasis GO:0055080 51 0.013
leg disc morphogenesis GO:0007478 80 0.013
eye pigment metabolic process GO:0042441 33 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
regulation of cellular component size GO:0032535 98 0.013
substrate adhesion dependent cell spreading GO:0034446 2 0.013
forebrain development GO:0030900 2 0.013
response to lipopolysaccharide GO:0032496 4 0.013
response to inorganic substance GO:0010035 44 0.013
tyrosine phosphorylation of stat protein GO:0007260 1 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
anatomical structure homeostasis GO:0060249 97 0.013
epithelium migration GO:0090132 148 0.013
spermatid development GO:0007286 98 0.013
sterol homeostasis GO:0055092 4 0.013
regulation of response to oxidative stress GO:1902882 4 0.013
cellular protein complex assembly GO:0043623 71 0.013
maintenance of location GO:0051235 73 0.013
wound healing GO:0042060 75 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.013
Human
positive regulation of cell motility GO:2000147 3 0.013
imaginal disc pattern formation GO:0007447 91 0.013
regulation of anatomical structure size GO:0090066 163 0.013
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.013
segmentation GO:0035282 207 0.012
regulation of response to external stimulus GO:0032101 115 0.012
cytokinesis GO:0000910 90 0.012
response to abiotic stimulus GO:0009628 341 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
Human
axis specification GO:0009798 167 0.012
inorganic cation transmembrane transport GO:0098662 61 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
actin filament organization GO:0007015 126 0.012
organophosphate metabolic process GO:0019637 195 0.012
Human
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
protein phosphorylation GO:0006468 169 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
response to hypoxia GO:0001666 53 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
transmembrane transport GO:0055085 139 0.012
regulation of cell cycle GO:0051726 291 0.012
regulation of rab protein signal transduction GO:0032483 7 0.012
camera type eye development GO:0043010 4 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
Human
photoreceptor cell differentiation GO:0046530 170 0.012
molting cycle chitin based cuticle GO:0007591 56 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.011
positive regulation of cell migration GO:0030335 2 0.011
cellular chemical homeostasis GO:0055082 40 0.011
gene silencing GO:0016458 138 0.011
membrane organization GO:0061024 112 0.011
taxis GO:0042330 304 0.011
ocellus pigmentation GO:0033060 19 0.011
organelle fusion GO:0048284 46 0.011
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.011
positive regulation of phagocytosis GO:0050766 3 0.011
regulation of gtpase activity GO:0043087 44 0.011
Human
developmental growth GO:0048589 280 0.011
phosphatidylinositol mediated signaling GO:0048015 4 0.011
epidermis development GO:0008544 65 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
response to organophosphorus GO:0046683 2 0.011
wing disc pattern formation GO:0035222 66 0.011
negative regulation of cell communication GO:0010648 223 0.011
digestive tract morphogenesis GO:0048546 127 0.011
nucleoside metabolic process GO:0009116 127 0.011
Human
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
cellular macromolecule localization GO:0070727 220 0.010
spermatid differentiation GO:0048515 114 0.010
synaptic vesicle localization GO:0097479 53 0.010
sensory perception of mechanical stimulus GO:0050954 72 0.010
regulation of membrane potential GO:0042391 35 0.010
bmp signaling pathway GO:0030509 27 0.010
regulation of secretion GO:0051046 44 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
regulation of organelle organization GO:0033043 196 0.010
small molecule metabolic process GO:0044281 305 0.010
Human
positive regulation of cellular component biogenesis GO:0044089 80 0.010
salivary gland development GO:0007431 162 0.010

sec71 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
disease of metabolism DOID:0014667 0 0.015