Drosophila melanogaster

44 known processes

salr (Dmel_CG4881)

spalt-related

(Aliases: 32F,sal,spalt,CG4881,Dmel\CG4881,Sal-r,Spalt,sal-r,salR,Cf3)

salr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 401 0.392
morphogenesis of an epithelium GO:0002009 276 0.273
Human Mouse
appendage morphogenesis GO:0035107 397 0.264
positive regulation of rna metabolic process GO:0051254 271 0.256
Human Mouse
dendrite development GO:0016358 204 0.255
positive regulation of nucleic acid templated transcription GO:1903508 266 0.173
Human Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.161
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.134
Human Mouse
compound eye development GO:0048749 307 0.131
embryonic development via the syncytial blastoderm GO:0001700 148 0.128
negative regulation of gene expression GO:0010629 387 0.126
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.122
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.120
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.117
Human Mouse
positive regulation of transcription dna templated GO:0045893 266 0.113
Human Mouse
dendrite morphogenesis GO:0048813 199 0.112
negative regulation of rna biosynthetic process GO:1902679 240 0.106
Human Mouse
taxis GO:0042330 304 0.103
gland development GO:0048732 191 0.099
Human
negative regulation of nucleic acid templated transcription GO:1903507 240 0.099
Human Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.095
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.095
Human Mouse
regionalization GO:0003002 416 0.094
muscle structure development GO:0061061 224 0.093
wing disc morphogenesis GO:0007472 344 0.091
forebrain development GO:0030900 2 0.087
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.087
Human Mouse
eye morphogenesis GO:0048592 260 0.083
cell fate specification GO:0001708 71 0.080
photoreceptor cell fate commitment GO:0046552 41 0.080
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.079
Human Mouse
respiratory system development GO:0060541 213 0.079
positive regulation of macromolecule metabolic process GO:0010604 405 0.077
Human Mouse
phagocytosis GO:0006909 215 0.077
tissue morphogenesis GO:0048729 297 0.075
Human Mouse
multi organism behavior GO:0051705 175 0.075
positive regulation of rna biosynthetic process GO:1902680 266 0.069
Human Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.068
tube morphogenesis GO:0035239 191 0.068
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.067
Human Mouse
regulation of neurogenesis GO:0050767 158 0.066
Mouse
negative regulation of cell differentiation GO:0045596 143 0.065
Mouse
multi organism reproductive behavior GO:0044705 121 0.064
vesicle mediated transport GO:0016192 381 0.064
imaginal disc derived wing morphogenesis GO:0007476 337 0.062
eye photoreceptor cell differentiation GO:0001754 145 0.061
neuron recognition GO:0008038 101 0.060
positive regulation of biosynthetic process GO:0009891 316 0.060
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.060
Human Mouse
brain development GO:0007420 120 0.059
Human Mouse
negative regulation of transcription dna templated GO:0045892 237 0.057
Human Mouse
negative regulation of rna metabolic process GO:0051253 251 0.057
Human Mouse
cell death GO:0008219 279 0.057
response to alcohol GO:0097305 95 0.056
compound eye photoreceptor cell differentiation GO:0001751 140 0.056
compound eye morphogenesis GO:0001745 249 0.056
neuron projection guidance GO:0097485 241 0.054
axis specification GO:0009798 167 0.053
imaginal disc derived wing vein specification GO:0007474 48 0.053
response to organic substance GO:0010033 284 0.053
Zebrafish
programmed cell death GO:0012501 257 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
Human Mouse
camera type eye development GO:0043010 4 0.051
neural precursor cell proliferation GO:0061351 75 0.049
Mouse
positive regulation of gene expression GO:0010628 290 0.048
Human Mouse
reproductive behavior GO:0019098 122 0.048
endocytosis GO:0006897 310 0.047
central nervous system development GO:0007417 201 0.047
Human Mouse
sensory organ morphogenesis GO:0090596 260 0.044
Human
response to oxygen containing compound GO:1901700 200 0.044
catabolic process GO:0009056 409 0.042
negative regulation of biosynthetic process GO:0009890 277 0.042
Human Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.041
cellular catabolic process GO:0044248 372 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.040
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.040
Human Mouse
neurological system process GO:0050877 358 0.039
regulation of cell cycle GO:0051726 291 0.038
eye antennal disc development GO:0035214 60 0.038
regulation of cellular amine metabolic process GO:0033238 3 0.038
epithelial tube morphogenesis GO:0060562 88 0.038
Mouse
establishment of ommatidial planar polarity GO:0042067 49 0.037
regulation of cell death GO:0010941 173 0.037
chaeta development GO:0022416 97 0.037
regulation of nervous system development GO:0051960 248 0.037
Mouse
regulation of organelle organization GO:0033043 196 0.037
muscle cell differentiation GO:0042692 103 0.036
aggressive behavior GO:0002118 63 0.036
inter male aggressive behavior GO:0002121 60 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.035
Mouse
blastoderm segmentation GO:0007350 159 0.035
stem cell maintenance GO:0019827 67 0.035
Mouse
photoreceptor cell differentiation GO:0046530 170 0.035
body morphogenesis GO:0010171 2 0.035
axon development GO:0061564 297 0.034
open tracheal system development GO:0007424 204 0.034
amine metabolic process GO:0009308 12 0.033
retina development in camera type eye GO:0060041 4 0.033
head development GO:0060322 135 0.033
Human Mouse
carboxylic acid metabolic process GO:0019752 92 0.033
striated muscle cell differentiation GO:0051146 90 0.033
stem cell differentiation GO:0048863 117 0.033
Mouse
malpighian tubule development GO:0072002 64 0.033
regulation of multicellular organismal development GO:2000026 414 0.032
Mouse
muscle cell development GO:0055001 50 0.032
eye development GO:0001654 323 0.032
lateral inhibition GO:0046331 206 0.031
cellular amine metabolic process GO:0044106 12 0.031
multicellular organismal reproductive behavior GO:0033057 110 0.031
compound eye photoreceptor fate commitment GO:0001752 36 0.030
organic acid metabolic process GO:0006082 103 0.030
regulation of cell development GO:0060284 215 0.030
Mouse
leg disc development GO:0035218 92 0.030
neural retina development GO:0003407 4 0.030
negative regulation of developmental process GO:0051093 201 0.029
Mouse
regulation of epidermal growth factor activated receptor activity GO:0007176 4 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
organonitrogen compound metabolic process GO:1901564 318 0.028
death GO:0016265 284 0.028
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.028
salivary gland development GO:0007431 162 0.028
intracellular transport GO:0046907 228 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
anterior posterior axis specification GO:0009948 109 0.028
negative regulation of signaling GO:0023057 219 0.027
Mouse
establishment of planar polarity GO:0001736 87 0.027
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
Zebrafish
developmental maturation GO:0021700 172 0.027
negative regulation of nervous system development GO:0051961 92 0.027
chaeta morphogenesis GO:0008407 42 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
apoptotic process GO:0006915 159 0.026
positive regulation of cell development GO:0010720 61 0.025
Mouse
mushroom body development GO:0016319 70 0.025
establishment of localization in cell GO:0051649 402 0.025
embryonic heart tube development GO:0035050 22 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
oxoacid metabolic process GO:0043436 103 0.025
positive regulation of signal transduction GO:0009967 223 0.025
Human Zebrafish
transcription from rna polymerase ii promoter GO:0006366 368 0.024
Human Mouse
male gamete generation GO:0048232 201 0.024
camera type eye morphogenesis GO:0048593 2 0.024
male courtship behavior veined wing generated song production GO:0045433 20 0.024
sterol homeostasis GO:0055092 4 0.023
retina morphogenesis in camera type eye GO:0060042 2 0.023
cellular macromolecule localization GO:0070727 220 0.023
segmentation GO:0035282 207 0.023
axonogenesis GO:0007409 290 0.022
chorion containing eggshell formation GO:0007304 105 0.022
regulation of erbb signaling pathway GO:1901184 42 0.022
antimicrobial peptide production GO:0002775 46 0.022
regulation of histone deacetylation GO:0031063 2 0.022
eggshell formation GO:0030703 105 0.022
establishment of vesicle localization GO:0051650 51 0.022
cellular response to chemical stimulus GO:0070887 199 0.021
Zebrafish
morphogenesis of a branching epithelium GO:0061138 45 0.021
Mouse
negative regulation of neurogenesis GO:0050768 53 0.021
positive regulation of histone deacetylation GO:0031065 2 0.021
small molecule metabolic process GO:0044281 305 0.020
neuron fate commitment GO:0048663 50 0.020
muscle organ development GO:0007517 127 0.020
regulation of cell cycle process GO:0010564 181 0.020
cell division GO:0051301 248 0.020
male courtship behavior veined wing extension GO:0048065 22 0.019
hindbrain development GO:0030902 2 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
spermatogenesis GO:0007283 200 0.019
olfactory behavior GO:0042048 97 0.019
regulation of neuron differentiation GO:0045664 103 0.018
Mouse
eye photoreceptor cell fate commitment GO:0042706 37 0.018
cell recognition GO:0008037 102 0.018
epithelial cell development GO:0002064 274 0.018
Human Mouse
response to organic cyclic compound GO:0014070 89 0.018
dorsal appendage formation GO:0046843 47 0.018
imaginal disc derived leg morphogenesis GO:0007480 80 0.018
growth GO:0040007 359 0.018
Mouse
negative regulation of response to stimulus GO:0048585 258 0.018
Mouse
regulation of mitotic cell cycle GO:0007346 190 0.018
positive regulation of protein deacetylation GO:0090312 2 0.018
mitotic nuclear division GO:0007067 213 0.018
protein localization GO:0008104 284 0.017
cellular ketone metabolic process GO:0042180 24 0.017
regulation of cell differentiation GO:0045595 302 0.017
Mouse
negative regulation of growth GO:0045926 84 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
Human Zebrafish
positive regulation of cell differentiation GO:0045597 64 0.017
Mouse
establishment of synaptic vesicle localization GO:0097480 50 0.017
axon guidance GO:0007411 233 0.017
regulation of localization GO:0032879 275 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
Mouse
intracellular signal transduction GO:0035556 300 0.016
cellular response to organic substance GO:0071310 132 0.016
Zebrafish
antennal development GO:0007469 25 0.016
rna localization GO:0006403 115 0.016
synapse organization GO:0050808 196 0.016
positive regulation of cell communication GO:0010647 250 0.016
Human Zebrafish
multi multicellular organism process GO:0044706 123 0.016
morphogenesis of a polarized epithelium GO:0001738 93 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
phospholipid homeostasis GO:0055091 1 0.016
actin filament organization GO:0007015 126 0.015
cilium organization GO:0044782 41 0.015
mating behavior GO:0007617 106 0.015
immune response GO:0006955 246 0.015
single organism cellular localization GO:1902580 180 0.015
telencephalon development GO:0021537 2 0.015
Human Mouse
regulation of dendrite development GO:0050773 37 0.015
sensory perception of sound GO:0007605 56 0.015
compound eye photoreceptor development GO:0042051 78 0.015
regulation of molecular function GO:0065009 217 0.015
cellular protein modification process GO:0006464 438 0.015
Mouse
branching morphogenesis of an epithelial tube GO:0048754 45 0.015
Mouse
renal system development GO:0072001 72 0.015
Human Mouse
sensory perception GO:0007600 196 0.015
leg disc morphogenesis GO:0007478 80 0.015
regulation of protein metabolic process GO:0051246 256 0.014
eye photoreceptor cell development GO:0042462 81 0.014
cellular protein localization GO:0034613 160 0.014
positive regulation of catabolic process GO:0009896 105 0.014
bmp signaling pathway GO:0030509 27 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
notum cell fate specification GO:0035310 5 0.014
exocrine system development GO:0035272 162 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
Mouse
regulation of protein deacetylation GO:0090311 2 0.014
nuclear import GO:0051170 51 0.013
embryonic morphogenesis GO:0048598 206 0.013
Human Zebrafish Mouse
establishment of organelle localization GO:0051656 122 0.013
cell cycle phase transition GO:0044770 140 0.013
ovarian follicle cell development GO:0030707 248 0.013
cholesterol homeostasis GO:0042632 3 0.013
mitotic spindle organization GO:0007052 220 0.013
chemotaxis GO:0006935 249 0.013
peripheral nervous system development GO:0007422 52 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
Zebrafish
negative regulation of cell cycle GO:0045786 116 0.013
notch signaling pathway GO:0007219 120 0.013
organic substance catabolic process GO:1901575 308 0.013
anterior posterior pattern specification GO:0009952 136 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
positive regulation of developmental process GO:0051094 143 0.013
Mouse
germ line stem cell maintenance GO:0030718 50 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of antimicrobial peptide production GO:0002784 44 0.013
intracellular protein transport GO:0006886 104 0.013
erbb signaling pathway GO:0038127 58 0.013
regulation of cellular catabolic process GO:0031329 157 0.012
protein modification process GO:0036211 438 0.012
Mouse
locomotory behavior GO:0007626 176 0.012
single organism behavior GO:0044708 391 0.012
endodermal cell fate commitment GO:0001711 3 0.012
ommatidial rotation GO:0016318 20 0.012
synaptic growth at neuromuscular junction GO:0051124 119 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
immune system process GO:0002376 347 0.012
single organism catabolic process GO:0044712 228 0.012
negative regulation of signal transduction GO:0009968 206 0.012
Mouse
organelle assembly GO:0070925 198 0.012
branching involved in open tracheal system development GO:0060446 45 0.012
phosphorylation GO:0016310 294 0.012
nuclear division GO:0000280 332 0.012
protein localization to organelle GO:0033365 82 0.012
regulation of proteolysis GO:0030162 87 0.012
regulation of catabolic process GO:0009894 170 0.012
protein processing GO:0016485 68 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
establishment of protein localization GO:0045184 163 0.012
carbohydrate metabolic process GO:0005975 82 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
kidney development GO:0001822 3 0.012
Human Mouse
regulation of intracellular signal transduction GO:1902531 236 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
single organism membrane organization GO:0044802 93 0.012
humoral immune response GO:0006959 117 0.012
regulation of mitosis GO:0007088 56 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
organelle fission GO:0048285 340 0.011
negative regulation of erbb signaling pathway GO:1901185 29 0.011
endomembrane system organization GO:0010256 119 0.011
chemosensory behavior GO:0007635 106 0.011
negative regulation of organelle organization GO:0010639 56 0.011
organ formation GO:0048645 39 0.011
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
Mouse
cell fate determination GO:0001709 91 0.011
gland morphogenesis GO:0022612 145 0.011
synaptic target recognition GO:0008039 45 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
embryonic axis specification GO:0000578 107 0.011
heterocycle catabolic process GO:0046700 166 0.011
tube development GO:0035295 244 0.011
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
response to biotic stimulus GO:0009607 294 0.011
response to extracellular stimulus GO:0009991 116 0.010
convergent extension GO:0060026 2 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
regulation of catalytic activity GO:0050790 185 0.010
positive regulation of notch signaling pathway GO:0045747 34 0.010
circulatory system development GO:0072359 82 0.010
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
glandular epithelial cell differentiation GO:0002067 1 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
regulation of sterol transport GO:0032371 1 0.010
protein import GO:0017038 55 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
adult behavior GO:0030534 137 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
eggshell chorion assembly GO:0007306 66 0.010
connective tissue development GO:0061448 3 0.010
muscle tissue development GO:0060537 30 0.010

salr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
disease of metabolism DOID:0014667 0 0.024
carbohydrate metabolism disease DOID:0050013 0 0.024
acquired metabolic disease DOID:0060158 0 0.024
cardiovascular system disease DOID:1287 0 0.022
diabetes mellitus DOID:9351 0 0.022
type 2 diabetes mellitus DOID:9352 0 0.022
glucose metabolism disease DOID:4194 0 0.022
inherited metabolic disorder DOID:655 0 0.020
nervous system disease DOID:863 0 0.015