Drosophila melanogaster

2 known processes

Hexo1 (Dmel_CG1318)

Hexosaminidase 1

(Aliases: DmHex1,HEXO1,HEX 1,Dmel\CG1318,HEX1,CG1318)

Hexo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.090
catabolic process GO:0009056 409 0.088
oxoacid metabolic process GO:0043436 103 0.085
carboxylic acid metabolic process GO:0019752 92 0.076
small molecule metabolic process GO:0044281 305 0.059
organic acid metabolic process GO:0006082 103 0.055
aging GO:0007568 143 0.055
cellular protein modification process GO:0006464 438 0.055
Fly
response to external biotic stimulus GO:0043207 293 0.054
protein modification process GO:0036211 438 0.051
Fly
single organism biosynthetic process GO:0044711 206 0.050
organonitrogen compound metabolic process GO:1901564 318 0.049
response to other organism GO:0051707 293 0.048
defense response to bacterium GO:0042742 178 0.045
response to bacterium GO:0009617 198 0.045
cellular catabolic process GO:0044248 372 0.044
organic substance catabolic process GO:1901575 308 0.044
homeostatic process GO:0042592 199 0.044
defense response to other organism GO:0098542 225 0.043
response to abiotic stimulus GO:0009628 341 0.043
response to organic substance GO:0010033 284 0.042
determination of adult lifespan GO:0008340 137 0.041
vesicle mediated transport GO:0016192 381 0.039
single organism catabolic process GO:0044712 228 0.039
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
respiratory system development GO:0060541 213 0.036
chemical homeostasis GO:0048878 92 0.035
response to biotic stimulus GO:0009607 294 0.034
open tracheal system development GO:0007424 204 0.034
immune system process GO:0002376 347 0.032
embryonic morphogenesis GO:0048598 206 0.032
appendage development GO:0048736 401 0.032
multicellular organismal aging GO:0010259 140 0.031
wing disc morphogenesis GO:0007472 344 0.030
endocytosis GO:0006897 310 0.028
cellular response to chemical stimulus GO:0070887 199 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.027
Fly
small molecule biosynthetic process GO:0044283 37 0.027
organic hydroxy compound metabolic process GO:1901615 83 0.026
carbohydrate metabolic process GO:0005975 82 0.025
Fly
response to endogenous stimulus GO:0009719 119 0.025
organic substance transport GO:0071702 257 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
ethanolamine containing compound metabolic process GO:0042439 4 0.024
developmental pigmentation GO:0048066 68 0.024
response to nitrogen compound GO:1901698 90 0.024
phagocytosis GO:0006909 215 0.024
regulation of localization GO:0032879 275 0.024
immune response GO:0006955 246 0.024
regulation of protein metabolic process GO:0051246 256 0.024
tube development GO:0035295 244 0.023
multi organism behavior GO:0051705 175 0.022
response to nutrient levels GO:0031667 114 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
single organism carbohydrate metabolic process GO:0044723 72 0.022
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.022
response to oxygen containing compound GO:1901700 200 0.022
eye pigmentation GO:0048069 43 0.021
lipid metabolic process GO:0006629 121 0.021
defense response to gram negative bacterium GO:0050829 94 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.020
body morphogenesis GO:0010171 2 0.020
gland development GO:0048732 191 0.020
protein complex assembly GO:0006461 200 0.020
endomembrane system organization GO:0010256 119 0.020
neuron recognition GO:0008038 101 0.020
cellular ketone metabolic process GO:0042180 24 0.020
cellular response to organic substance GO:0071310 132 0.020
macromolecular complex assembly GO:0065003 256 0.019
phosphorylation GO:0016310 294 0.019
response to copper ion GO:0046688 4 0.019
cellular homeostasis GO:0019725 80 0.019
hormone catabolic process GO:0042447 3 0.019
cell proliferation GO:0008283 299 0.019
chemotaxis GO:0006935 249 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
cell death GO:0008219 279 0.019
neuron projection guidance GO:0097485 241 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
response to monosaccharide GO:0034284 4 0.018
regulation of cell cycle GO:0051726 291 0.018
xenobiotic catabolic process GO:0042178 1 0.018
cellular amine metabolic process GO:0044106 12 0.018
lipid localization GO:0010876 54 0.018
establishment of localization in cell GO:0051649 402 0.017
response to organophosphorus GO:0046683 2 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
positive regulation of developmental process GO:0051094 143 0.017
response to extracellular stimulus GO:0009991 116 0.017
glycoprotein metabolic process GO:0009100 41 0.017
Fly
anion homeostasis GO:0055081 3 0.017
regulation of anatomical structure size GO:0090066 163 0.016
tube morphogenesis GO:0035239 191 0.016
lateral inhibition GO:0046331 206 0.016
pigmentation GO:0043473 75 0.016
developmental growth GO:0048589 280 0.016
cellular chemical homeostasis GO:0055082 40 0.016
taxis GO:0042330 304 0.016
positive regulation of cell communication GO:0010647 250 0.016
ion transport GO:0006811 145 0.016
salivary gland morphogenesis GO:0007435 145 0.016
neurological system process GO:0050877 358 0.016
response to lipopolysaccharide GO:0032496 4 0.016
positive regulation of signal transduction GO:0009967 223 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
regionalization GO:0003002 416 0.015
cell motility GO:0048870 251 0.015
cellular iron ion homeostasis GO:0006879 3 0.015
proteolysis GO:0006508 192 0.015
central nervous system development GO:0007417 201 0.015
Fly
organophosphate metabolic process GO:0019637 195 0.015
positive regulation of signaling GO:0023056 243 0.015
cellular transition metal ion homeostasis GO:0046916 9 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
alditol phosphate metabolic process GO:0052646 2 0.014
death GO:0016265 284 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
amine metabolic process GO:0009308 12 0.014
cell adhesion GO:0007155 136 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
detection of stimulus GO:0051606 156 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
secondary metabolic process GO:0019748 75 0.014
lipid storage GO:0019915 38 0.014
maintenance of location GO:0051235 73 0.013
regulation of transport GO:0051049 181 0.013
appendage morphogenesis GO:0035107 397 0.013
response to inorganic substance GO:0010035 44 0.013
polyol biosynthetic process GO:0046173 3 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
macromolecule catabolic process GO:0009057 161 0.013
protein complex biogenesis GO:0070271 201 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
kidney development GO:0001822 3 0.013
regulation of proteolysis GO:0030162 87 0.013
hindbrain development GO:0030902 2 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
estrogen metabolic process GO:0008210 1 0.013
secretion by cell GO:0032940 101 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
response to organonitrogen compound GO:0010243 75 0.012
aggressive behavior GO:0002118 63 0.012
nuclear division GO:0000280 332 0.012
response to light stimulus GO:0009416 124 0.012
growth GO:0040007 359 0.012
Fly
exocrine system development GO:0035272 162 0.012
hormone metabolic process GO:0042445 33 0.012
epithelial cell differentiation GO:0030855 322 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
regulation of response to stress GO:0080134 200 0.012
regulation of apoptotic process GO:0042981 130 0.012
organelle fission GO:0048285 340 0.012
camera type eye development GO:0043010 4 0.012
regulation of tube size GO:0035150 46 0.012
cell migration GO:0016477 238 0.012
secretion GO:0046903 109 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
programmed cell death GO:0012501 257 0.011
response to decreased oxygen levels GO:0036293 58 0.011
response to starvation GO:0042594 97 0.011
intracellular signal transduction GO:0035556 300 0.011
regulation of developmental growth GO:0048638 174 0.011
positive regulation of cell motility GO:2000147 3 0.011
salivary gland development GO:0007431 162 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
positive regulation of transport GO:0051050 92 0.011
response to glucose GO:0009749 2 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
positive regulation of cell migration GO:0030335 2 0.011
response to hexose GO:0009746 3 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
response to radiation GO:0009314 155 0.011
cellular metal ion homeostasis GO:0006875 31 0.011
digestive tract morphogenesis GO:0048546 127 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
regulation of organelle organization GO:0033043 196 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
response to oxygen levels GO:0070482 59 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
regulation of lipid transport GO:0032368 3 0.010
cellular lipid metabolic process GO:0044255 83 0.010
axon development GO:0061564 297 0.010
thioester metabolic process GO:0035383 3 0.010
purine containing compound metabolic process GO:0072521 155 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
single organism behavior GO:0044708 391 0.010
axonogenesis GO:0007409 290 0.010
positive regulation of molecular function GO:0044093 136 0.010
regulation of catalytic activity GO:0050790 185 0.010
mating GO:0007618 120 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010

Hexo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.014
nervous system disease DOID:863 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
cardiovascular system disease DOID:1287 0 0.012
diabetes mellitus DOID:9351 0 0.011
type 2 diabetes mellitus DOID:9352 0 0.011
glucose metabolism disease DOID:4194 0 0.011