Drosophila melanogaster

17 known processes

betaTub85D (Dmel_CG9359)

beta-Tubulin at 85D

(Aliases: beta-tub85D,BETA 85D,beta-Tub85D,beta2tub,ms(3)KK[D],D.m.BETA-85D,B2t,beta(2)Tub,DTB4,betaTub2,beta-tub,BETA2,Tub,beta2,beta85D,2t,beta2t,beta(2)Tu,Dmbeta2,Dmel\CG9359,beta[[2]]-tubulin,CG9359)

betaTub85D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid differentiation GO:0048515 114 0.999
spermatid development GO:0007286 98 0.985
male gamete generation GO:0048232 201 0.981
spermatogenesis GO:0007283 200 0.974
sperm individualization GO:0007291 48 0.947
cellularization GO:0007349 90 0.861
organelle assembly GO:0070925 198 0.818
male meiosis cytokinesis GO:0007112 26 0.757
cytoskeleton dependent cytokinesis GO:0061640 81 0.604
spindle organization GO:0007051 253 0.551
meiotic cytokinesis GO:0033206 33 0.534
cell death GO:0008219 279 0.352
cell division GO:0051301 248 0.347
meiotic cell cycle process GO:1903046 132 0.335
axoneme assembly GO:0035082 18 0.329
actin filament based process GO:0030029 220 0.314
cytokinesis GO:0000910 90 0.307
meiosis ii GO:0007135 23 0.301
programmed cell death GO:0012501 257 0.289
positive regulation of endopeptidase activity GO:0010950 26 0.266
meiotic spindle organization GO:0000212 36 0.237
cellular catabolic process GO:0044248 372 0.227
positive regulation of peptidase activity GO:0010952 29 0.220
organelle fission GO:0048285 340 0.212
proteolysis GO:0006508 192 0.210
oxoacid metabolic process GO:0043436 103 0.202
chromosome organization GO:0051276 360 0.197
meiosis i GO:0007127 59 0.188
positive regulation of macromolecule metabolic process GO:0010604 405 0.183
histolysis GO:0007559 102 0.183
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.168
regulation of protein metabolic process GO:0051246 256 0.166
actomyosin structure organization GO:0031032 56 0.166
positive regulation of cellular biosynthetic process GO:0031328 316 0.163
positive regulation of biosynthetic process GO:0009891 316 0.163
positive regulation of cellular protein metabolic process GO:0032270 118 0.156
small molecule metabolic process GO:0044281 305 0.150
organonitrogen compound metabolic process GO:1901564 318 0.145
death GO:0016265 284 0.142
sensory perception of sound GO:0007605 56 0.130
negative regulation of cellular metabolic process GO:0031324 382 0.123
actin cytoskeleton organization GO:0030036 206 0.122
single organism behavior GO:0044708 391 0.113
very long chain fatty acid metabolic process GO:0000038 4 0.109
catabolic process GO:0009056 409 0.103
organic substance catabolic process GO:1901575 308 0.099
single organism membrane fusion GO:0044801 42 0.096
gland morphogenesis GO:0022612 145 0.093
organelle fusion GO:0048284 46 0.093
intercellular bridge organization GO:0043063 14 0.091
membrane organization GO:0061024 112 0.089
mesoderm development GO:0007498 78 0.088
axon cargo transport GO:0008088 29 0.084
macromolecular complex assembly GO:0065003 256 0.084
exocrine system development GO:0035272 162 0.083
immune system process GO:0002376 347 0.083
response to abiotic stimulus GO:0009628 341 0.082
gland development GO:0048732 191 0.081
regulation of microtubule based process GO:0032886 49 0.079
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.077
actomyosin contractile ring assembly GO:0000915 10 0.076
regulation of apoptotic process GO:0042981 130 0.076
neurological system process GO:0050877 358 0.076
tissue death GO:0016271 102 0.076
ribonucleotide metabolic process GO:0009259 145 0.075
central nervous system development GO:0007417 201 0.073
cytoplasmic transport GO:0016482 130 0.073
developmental programmed cell death GO:0010623 138 0.073
nuclear division GO:0000280 332 0.071
regulation of cell death GO:0010941 173 0.071
positive regulation of proteolysis GO:0045862 52 0.070
apoptotic process GO:0006915 159 0.070
regulation of programmed cell death GO:0043067 152 0.069
organic acid metabolic process GO:0006082 103 0.066
response to organic substance GO:0010033 284 0.066
sensory perception of mechanical stimulus GO:0050954 72 0.065
protein modification process GO:0036211 438 0.064
regulation of proteolysis GO:0030162 87 0.064
single organism catabolic process GO:0044712 228 0.064
cellular component assembly involved in morphogenesis GO:0010927 151 0.063
regulation of cellular protein metabolic process GO:0032268 243 0.063
response to glucose GO:0009749 2 0.061
positive regulation of protein metabolic process GO:0051247 128 0.061
negative regulation of developmental process GO:0051093 201 0.060
aging GO:0007568 143 0.060
sperm axoneme assembly GO:0007288 13 0.059
negative regulation of cellular component organization GO:0051129 108 0.058
intracellular signal transduction GO:0035556 300 0.056
nucleobase containing small molecule metabolic process GO:0055086 174 0.056
regulation of cell development GO:0060284 215 0.055
cellular protein modification process GO:0006464 438 0.055
positive regulation of programmed cell death GO:0043068 62 0.055
response to oxygen containing compound GO:1901700 200 0.054
establishment of localization in cell GO:0051649 402 0.052
meiotic cell cycle GO:0051321 171 0.052
posttranscriptional regulation of gene expression GO:0010608 145 0.052
regulation of endopeptidase activity GO:0052548 36 0.050
activation of cysteine type endopeptidase activity GO:0097202 17 0.049
response to symbiotic bacterium GO:0009609 2 0.048
positive regulation of gene expression GO:0010628 290 0.047
sex differentiation GO:0007548 81 0.045
organophosphate metabolic process GO:0019637 195 0.045
microtubule based movement GO:0007018 51 0.044
positive regulation of response to stimulus GO:0048584 323 0.044
single organism membrane organization GO:0044802 93 0.044
protein modification by small protein conjugation GO:0032446 79 0.044
positive regulation of cell death GO:0010942 69 0.044
spermatocyte division GO:0048137 13 0.043
appendage development GO:0048736 401 0.043
carbohydrate derivative metabolic process GO:1901135 217 0.043
homeostatic process GO:0042592 199 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.042
nucleoside phosphate metabolic process GO:0006753 162 0.041
lateral inhibition GO:0046331 206 0.041
nucleotide metabolic process GO:0009117 161 0.041
positive regulation of molecular function GO:0044093 136 0.040
actomyosin contractile ring organization GO:0044837 10 0.040
negative regulation of cell differentiation GO:0045596 143 0.039
purine nucleotide metabolic process GO:0006163 146 0.039
developmental growth GO:0048589 280 0.038
sensory perception GO:0007600 196 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
multicellular organismal aging GO:0010259 140 0.037
regulation of localization GO:0032879 275 0.037
regulation of cell cycle phase transition GO:1901987 130 0.037
head development GO:0060322 135 0.037
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.034
cellular macromolecule catabolic process GO:0044265 136 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
nucleoside metabolic process GO:0009116 127 0.034
regulation of cell division GO:0051302 72 0.034
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.034
mitotic nuclear division GO:0007067 213 0.033
response to other organism GO:0051707 293 0.032
positive regulation of apoptotic process GO:0043065 47 0.032
eye morphogenesis GO:0048592 260 0.032
positive regulation of phosphorylation GO:0042327 87 0.032
mitochondrion organization GO:0007005 65 0.032
phosphorylation GO:0016310 294 0.032
wing disc morphogenesis GO:0007472 344 0.032
regulation of cellular catabolic process GO:0031329 157 0.032
protein complex biogenesis GO:0070271 201 0.031
cell cell signaling involved in cell fate commitment GO:0045168 210 0.031
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.031
cellular homeostasis GO:0019725 80 0.031
ribose phosphate metabolic process GO:0019693 145 0.030
extracellular structure organization GO:0043062 46 0.030
purine containing compound metabolic process GO:0072521 155 0.030
mitochondrial fusion GO:0008053 7 0.030
protein dna complex subunit organization GO:0071824 86 0.030
respiratory system development GO:0060541 213 0.030
microtubule bundle formation GO:0001578 27 0.029
cellular response to organic substance GO:0071310 132 0.029
regulation of translation GO:0006417 56 0.029
glycosyl compound metabolic process GO:1901657 127 0.028
salivary gland cell autophagic cell death GO:0035071 83 0.028
regulation of neurogenesis GO:0050767 158 0.028
single organism intracellular transport GO:1902582 207 0.028
rhythmic behavior GO:0007622 76 0.028
response to hypoxia GO:0001666 53 0.027
compound eye development GO:0048749 307 0.027
vesicle mediated transport GO:0016192 381 0.027
very long chain fatty acid biosynthetic process GO:0042761 2 0.027
brain development GO:0007420 120 0.027
atp metabolic process GO:0046034 49 0.026
eye photoreceptor cell differentiation GO:0001754 145 0.026
protein complex assembly GO:0006461 200 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
positive regulation of signaling GO:0023056 243 0.026
macromolecule catabolic process GO:0009057 161 0.026
microtubule organizing center organization GO:0031023 168 0.025
Fly
purine nucleoside metabolic process GO:0042278 127 0.025
response to endogenous stimulus GO:0009719 119 0.025
regulation of phosphorylation GO:0042325 147 0.025
response to hexose GO:0009746 3 0.025
salivary gland morphogenesis GO:0007435 145 0.025
autophagic cell death GO:0048102 83 0.025
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.025
translation GO:0006412 69 0.025
positive regulation of rna metabolic process GO:0051254 271 0.025
single organism biosynthetic process GO:0044711 206 0.024
organophosphate catabolic process GO:0046434 112 0.024
response to monosaccharide GO:0034284 4 0.024
microtubule based transport GO:0010970 42 0.024
protein depolymerization GO:0051261 31 0.024
intracellular transport GO:0046907 228 0.023
ovarian nurse cell to oocyte transport GO:0007300 27 0.023
chromosome separation GO:0051304 42 0.023
regulation of catalytic activity GO:0050790 185 0.023
regulation of nervous system development GO:0051960 248 0.022
negative regulation of cell cycle process GO:0010948 109 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
response to external biotic stimulus GO:0043207 293 0.022
response to biotic stimulus GO:0009607 294 0.022
regionalization GO:0003002 416 0.022
protein localization GO:0008104 284 0.022
striated muscle cell differentiation GO:0051146 90 0.022
determination of adult lifespan GO:0008340 137 0.021
development of primary sexual characteristics GO:0045137 50 0.021
salivary gland histolysis GO:0035070 88 0.021
photoreceptor cell differentiation GO:0046530 170 0.021
monocarboxylic acid metabolic process GO:0032787 29 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
germarium derived egg chamber formation GO:0007293 101 0.020
tube development GO:0035295 244 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
cellular protein catabolic process GO:0044257 83 0.020
phagocytosis GO:0006909 215 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
regulation of multicellular organismal development GO:2000026 414 0.019
regulation of cell differentiation GO:0045595 302 0.019
protein maturation GO:0051604 71 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
growth GO:0040007 359 0.019
response to decreased oxygen levels GO:0036293 58 0.019
salivary gland development GO:0007431 162 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
sperm mitochondrion organization GO:0030382 7 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
mitotic spindle organization GO:0007052 220 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
epithelial cell differentiation GO:0030855 322 0.017
spindle assembly GO:0051225 80 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
lipid localization GO:0010876 54 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
sister chromatid segregation GO:0000819 92 0.017
monocarboxylic acid transport GO:0015718 3 0.017
maintenance of location GO:0051235 73 0.017
positive regulation of translation GO:0045727 12 0.017
forebrain development GO:0030900 2 0.017
immune system development GO:0002520 57 0.017
circadian behavior GO:0048512 76 0.017
negative regulation of signal transduction GO:0009968 206 0.017
nucleus organization GO:0006997 45 0.016
ovarian follicle cell development GO:0030707 248 0.016
positive regulation of cell communication GO:0010647 250 0.016
contractile ring contraction GO:0036213 12 0.016
negative regulation of cellular response to oxidative stress GO:1900408 1 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
endocytosis GO:0006897 310 0.016
learning GO:0007612 75 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
gonad development GO:0008406 50 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
cell proliferation GO:0008283 299 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
nitrogen compound transport GO:0071705 85 0.016
gliogenesis GO:0042063 80 0.016
cell cycle phase transition GO:0044770 140 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
cilium morphogenesis GO:0060271 39 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
nucleoside monophosphate metabolic process GO:0009123 52 0.015
protein processing GO:0016485 68 0.015
fatty acid elongation GO:0030497 3 0.015
protein ubiquitination GO:0016567 70 0.015
positive regulation of transport GO:0051050 92 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
body morphogenesis GO:0010171 2 0.014
cell projection assembly GO:0030031 94 0.014
muscle cell differentiation GO:0042692 103 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
cell motility GO:0048870 251 0.014
Human Rat
open tracheal system development GO:0007424 204 0.014
regulation of organelle organization GO:0033043 196 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
negative regulation of neurogenesis GO:0050768 53 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
ribonucleoside monophosphate metabolic process GO:0009161 51 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
regulation of anatomical structure size GO:0090066 163 0.013
cellular ketone metabolic process GO:0042180 24 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
response to organic cyclic compound GO:0014070 89 0.013
defense response GO:0006952 300 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
organic anion transport GO:0015711 28 0.013
translational initiation GO:0006413 11 0.013
synaptic transmission GO:0007268 288 0.013
lipid biosynthetic process GO:0008610 46 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
response to starvation GO:0042594 97 0.013
cation transport GO:0006812 110 0.012
asymmetric cell division GO:0008356 37 0.012
response to extracellular stimulus GO:0009991 116 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
regulation of cell cycle GO:0051726 291 0.012
amine metabolic process GO:0009308 12 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
chemical homeostasis GO:0048878 92 0.012
mitotic cytokinesis GO:0000281 50 0.012
negative regulation of nervous system development GO:0051961 92 0.012
ion homeostasis GO:0050801 55 0.012
stem cell division GO:0017145 69 0.012
response to temperature stimulus GO:0009266 106 0.012
regulation of cellular localization GO:0060341 136 0.012
stem cell differentiation GO:0048863 117 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.012
hemopoiesis GO:0030097 46 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
response to alcohol GO:0097305 95 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
cellular amide metabolic process GO:0043603 80 0.011
sensory perception of pain GO:0019233 4 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
spindle checkpoint GO:0031577 11 0.011
response to oxygen levels GO:0070482 59 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.010
negative regulation of cell division GO:0051782 17 0.010
regulation of response to stress GO:0080134 200 0.010
regulation of locomotion GO:0040012 42 0.010
membrane fusion GO:0061025 42 0.010
syncytium formation GO:0006949 43 0.010
eye development GO:0001654 323 0.010
meiosis i cytokinesis GO:0007110 12 0.010
mushroom body development GO:0016319 70 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
meiotic nuclear division GO:0007126 151 0.010
lipid homeostasis GO:0055088 33 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010

betaTub85D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.138
nervous system disease DOID:863 0 0.027
disease of cellular proliferation DOID:14566 0 0.021
cancer DOID:162 0 0.017
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
synucleinopathy DOID:0050890 0 0.011