Drosophila melanogaster

55 known processes

Mcm5 (Dmel_CG4082)

Minichromosome maintenance 5

(Aliases: CG4082,DmMcm5,DmCDC465,McM5,DmMCM5,MCM5,mcm5,PCR4,DmeMCM5,Dmel\CG4082,DmCDC46)

Mcm5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear dna replication GO:0033260 1 0.992
Yeast
dna recombination GO:0006310 32 0.911
meiotic chromosome segregation GO:0045132 59 0.834
dna metabolic process GO:0006259 227 0.829
dna packaging GO:0006323 91 0.733
reciprocal meiotic recombination GO:0007131 19 0.674
dna replication initiation GO:0006270 6 0.640
Yeast
dna replication GO:0006260 48 0.620
organelle fission GO:0048285 340 0.571
dna geometric change GO:0032392 16 0.553
cell cycle dna replication GO:0044786 23 0.551
double strand break repair via homologous recombination GO:0000724 13 0.549
Yeast
macromolecular complex assembly GO:0065003 256 0.508
Yeast
chromosome condensation GO:0030261 41 0.446
dna conformation change GO:0071103 105 0.430
cellular macromolecular complex assembly GO:0034622 153 0.426
Yeast
spindle organization GO:0007051 253 0.422
double strand break repair GO:0006302 26 0.391
Yeast
cellular catabolic process GO:0044248 372 0.378
Yeast
negative regulation of cellular metabolic process GO:0031324 382 0.366
Yeast
meiotic cell cycle GO:0051321 171 0.365
catabolic process GO:0009056 409 0.346
Yeast
dna repair GO:0006281 54 0.334
Yeast
nucleobase containing compound catabolic process GO:0034655 165 0.328
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.321
Yeast
death GO:0016265 284 0.299
Zebrafish
protein dna complex assembly GO:0065004 63 0.289
Yeast
meiotic nuclear division GO:0007126 151 0.289
dna endoreduplication GO:0042023 22 0.279
nuclear division GO:0000280 332 0.265
ribonucleoside monophosphate catabolic process GO:0009158 39 0.231
Yeast
mitotic spindle organization GO:0007052 220 0.226
protein complex biogenesis GO:0070271 201 0.221
cell death GO:0008219 279 0.207
Zebrafish
aromatic compound catabolic process GO:0019439 166 0.204
Yeast
chromosome segregation GO:0007059 157 0.195
heterocycle catabolic process GO:0046700 166 0.181
Yeast
male meiosis GO:0007140 52 0.179
positive regulation of macromolecule metabolic process GO:0010604 405 0.177
Yeast
recombinational repair GO:0000725 13 0.171
Yeast
organic substance catabolic process GO:1901575 308 0.167
Yeast
cellular nitrogen compound catabolic process GO:0044270 165 0.163
Yeast
negative regulation of cell cycle process GO:0010948 109 0.162
g2 dna damage checkpoint GO:0031572 69 0.158
female meiotic division GO:0007143 70 0.154
carbohydrate derivative metabolic process GO:1901135 217 0.150
Yeast
protein complex assembly GO:0006461 200 0.143
dna dependent dna replication GO:0006261 17 0.138
Yeast
small molecule metabolic process GO:0044281 305 0.133
Yeast
protein dna complex subunit organization GO:0071824 86 0.128
Yeast
regulation of catabolic process GO:0009894 170 0.124
regulation of phosphate metabolic process GO:0019220 210 0.123
organic cyclic compound catabolic process GO:1901361 168 0.120
Yeast
protein localization GO:0008104 284 0.119
regulation of hydrolase activity GO:0051336 97 0.109
purine containing compound metabolic process GO:0072521 155 0.105
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.098
Yeast
mitotic g2 m transition checkpoint GO:0044818 70 0.096
atp metabolic process GO:0046034 49 0.089
Yeast
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.085
chromosome separation GO:0051304 42 0.083
spindle assembly involved in mitosis GO:0090307 50 0.083
cellular macromolecule localization GO:0070727 220 0.081
regulation of dna metabolic process GO:0051052 34 0.079
Yeast
establishment of localization in cell GO:0051649 402 0.078
regulation of cell cycle phase transition GO:1901987 130 0.076
single organism biosynthetic process GO:0044711 206 0.073
organonitrogen compound metabolic process GO:1901564 318 0.073
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.071
Worm
mitotic cell cycle phase transition GO:0044772 138 0.070
mitotic cell cycle checkpoint GO:0007093 88 0.068
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.068
Yeast
regulation of catalytic activity GO:0050790 185 0.068
single organism catabolic process GO:0044712 228 0.067
Yeast
mitotic nuclear division GO:0007067 213 0.067
programmed cell death GO:0012501 257 0.066
Zebrafish
proteolysis GO:0006508 192 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.061
Yeast
cell motility GO:0048870 251 0.060
chromosome organization GO:0051276 360 0.060
regulation of cell cycle process GO:0010564 181 0.059
sister chromatid segregation GO:0000819 92 0.058
ribonucleoside triphosphate catabolic process GO:0009203 108 0.058
Yeast
mitotic g2 dna damage checkpoint GO:0007095 69 0.057
purine ribonucleoside metabolic process GO:0046128 127 0.056
Yeast
purine ribonucleotide catabolic process GO:0009154 109 0.056
Yeast
nucleoside catabolic process GO:0009164 112 0.055
Yeast
cellular protein complex assembly GO:0043623 71 0.055
establishment of protein localization GO:0045184 163 0.054
regulation of molecular function GO:0065009 217 0.054
purine nucleoside triphosphate metabolic process GO:0009144 119 0.054
Yeast
positive regulation of catalytic activity GO:0043085 118 0.054
ribonucleoside metabolic process GO:0009119 127 0.052
Yeast
glycosyl compound catabolic process GO:1901658 112 0.052
Yeast
apoptotic process GO:0006915 159 0.051
Zebrafish
protein modification by small protein conjugation GO:0032446 79 0.050
glycosyl compound metabolic process GO:1901657 127 0.050
Yeast
ribose phosphate metabolic process GO:0019693 145 0.050
Yeast
mitotic chromosome condensation GO:0007076 22 0.049
cell division GO:0051301 248 0.048
single organism cellular localization GO:1902580 180 0.048
chromatin silencing GO:0006342 76 0.047
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.047
Yeast
purine ribonucleoside catabolic process GO:0046130 112 0.046
Yeast
reproductive structure development GO:0048608 74 0.046
female meiosis chromosome segregation GO:0016321 33 0.045
purine nucleotide catabolic process GO:0006195 109 0.044
Yeast
reproductive system development GO:0061458 74 0.044
cell cycle checkpoint GO:0000075 95 0.044
purine nucleotide metabolic process GO:0006163 146 0.044
Yeast
nucleoside metabolic process GO:0009116 127 0.044
Yeast
centrosome organization GO:0051297 163 0.044
dna amplification GO:0006277 11 0.043
male gamete generation GO:0048232 201 0.043
regulation of mitotic cell cycle phase transition GO:1901990 130 0.042
purine nucleoside catabolic process GO:0006152 112 0.042
Yeast
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.041
purine nucleoside metabolic process GO:0042278 127 0.041
Yeast
protein transport GO:0015031 155 0.040
spindle assembly GO:0051225 80 0.040
regulation of cell cycle GO:0051726 291 0.039
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.039
Yeast
organic substance transport GO:0071702 257 0.039
nucleoside monophosphate metabolic process GO:0009123 52 0.039
Yeast
nucleoside phosphate metabolic process GO:0006753 162 0.039
Yeast
negative regulation of gene expression GO:0010629 387 0.038
Yeast
microtubule polymerization or depolymerization GO:0031109 39 0.037
single organism intracellular transport GO:1902582 207 0.037
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.037
negative regulation of mitotic cell cycle GO:0045930 109 0.036
cellular protein localization GO:0034613 160 0.036
gene silencing GO:0016458 138 0.036
Yeast
dna duplex unwinding GO:0032508 16 0.035
sex differentiation GO:0007548 81 0.035
regulation of triglyceride catabolic process GO:0010896 1 0.035
mitotic dna integrity checkpoint GO:0044774 75 0.035
ribonucleoside monophosphate metabolic process GO:0009161 51 0.035
Yeast
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.035
dna catabolic process GO:0006308 16 0.035
regulation of cellular catabolic process GO:0031329 157 0.035
negative regulation of gene expression epigenetic GO:0045814 77 0.035
Yeast
nucleoside triphosphate catabolic process GO:0009143 108 0.035
Yeast
cell cycle g1 s phase transition GO:0044843 31 0.034
regulation of nucleotide catabolic process GO:0030811 48 0.034
protein maturation GO:0051604 71 0.034
negative regulation of rna biosynthetic process GO:1902679 240 0.033
Yeast
organic acid metabolic process GO:0006082 103 0.033
positive regulation of molecular function GO:0044093 136 0.033
cell cycle phase transition GO:0044770 140 0.033
ribonucleotide metabolic process GO:0009259 145 0.032
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 108 0.032
Yeast
nucleotide metabolic process GO:0009117 161 0.032
Yeast
microtubule organizing center organization GO:0031023 168 0.031
regulation of cytoskeleton organization GO:0051493 89 0.031
regulation of small gtpase mediated signal transduction GO:0051056 93 0.030
protein processing GO:0016485 68 0.030
purine containing compound catabolic process GO:0072523 112 0.030
Yeast
ribonucleotide catabolic process GO:0009261 109 0.030
Yeast
development of primary sexual characteristics GO:0045137 50 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.030
Yeast
mitotic sister chromatid separation GO:0051306 30 0.029
purine nucleoside monophosphate metabolic process GO:0009126 50 0.028
Yeast
regulation of mitotic cell cycle GO:0007346 190 0.028
gonad development GO:0008406 50 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
Yeast
regulation of nucleotide metabolic process GO:0006140 62 0.027
positive regulation of programmed cell death GO:0043068 62 0.027
double strand break repair via nonhomologous end joining GO:0006303 5 0.027
mitotic dna damage checkpoint GO:0044773 74 0.027
microtubule anchoring GO:0034453 11 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
Yeast
dna damage checkpoint GO:0000077 78 0.026
organophosphate metabolic process GO:0019637 195 0.025
Yeast
macromolecule catabolic process GO:0009057 161 0.025
organelle assembly GO:0070925 198 0.025
negative regulation of cell cycle GO:0045786 116 0.024
oxoacid metabolic process GO:0043436 103 0.024
regulation of proteolysis GO:0030162 87 0.024
muscle organ development GO:0007517 127 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
localization of cell GO:0051674 257 0.023
ribonucleoside catabolic process GO:0042454 112 0.023
Yeast
larval development GO:0002164 104 0.023
meiosis i GO:0007127 59 0.022
organophosphate catabolic process GO:0046434 112 0.022
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
Yeast
response to biotic stimulus GO:0009607 294 0.022
negative regulation of cell cycle phase transition GO:1901988 103 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
Yeast
positive regulation of hydrolase activity GO:0051345 78 0.021
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.021
dendrite development GO:0016358 204 0.021
regulation of cell death GO:0010941 173 0.021
Zebrafish
dna integrity checkpoint GO:0031570 81 0.020
protein catabolic process GO:0030163 101 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.019
Yeast
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
intracellular protein transport GO:0006886 104 0.019
pole cell migration GO:0007280 13 0.019
purine nucleoside monophosphate catabolic process GO:0009128 38 0.019
Yeast
endocytosis GO:0006897 310 0.019
regulation of dna replication GO:0006275 13 0.018
Yeast
positive regulation of cellular catabolic process GO:0031331 95 0.018
nucleoside phosphate catabolic process GO:1901292 110 0.018
Yeast
positive regulation of phosphate metabolic process GO:0045937 139 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
Yeast
protein localization to organelle GO:0033365 82 0.018
response to oxygen containing compound GO:1901700 200 0.018
cellular protein catabolic process GO:0044257 83 0.018
mitotic sister chromatid segregation GO:0000070 87 0.018
cellular macromolecule catabolic process GO:0044265 136 0.017
metaphase anaphase transition of cell cycle GO:0044784 28 0.017
muscle structure development GO:0061061 224 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
Yeast
spermatogenesis GO:0007283 200 0.016
actin filament based process GO:0030029 220 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
cellular protein modification process GO:0006464 438 0.016
vesicle mediated transport GO:0016192 381 0.015
atp catabolic process GO:0006200 38 0.015
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
Yeast
regulation of localization GO:0032879 275 0.015
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.015
snrna metabolic process GO:0016073 14 0.015
memory GO:0007613 94 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
nucleotide catabolic process GO:0009166 109 0.014
Yeast
cytokinesis GO:0000910 90 0.014
meiotic cell cycle process GO:1903046 132 0.014
negative regulation of nucleotide metabolic process GO:0045980 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
g1 s transition of mitotic cell cycle GO:0000082 31 0.014
negative regulation of catabolic process GO:0009895 36 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
negative regulation of sister chromatid segregation GO:0033046 13 0.013
response to wounding GO:0009611 94 0.013
protein polymerization GO:0051258 42 0.013
cell proliferation GO:0008283 299 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
Yeast
regulation of ras gtpase activity GO:0032318 38 0.013
cytoplasmic transport GO:0016482 130 0.013
response to other organism GO:0051707 293 0.012
genitalia development GO:0048806 26 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
protein import GO:0017038 55 0.012
protein ubiquitination GO:0016567 70 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
Yeast
mitotic spindle checkpoint GO:0071174 11 0.012
body morphogenesis GO:0010171 2 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
epithelial cell differentiation GO:0030855 322 0.011
response to endogenous stimulus GO:0009719 119 0.011
multicellular organismal aging GO:0010259 140 0.011
regulation of chromosome organization GO:0033044 64 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
Yeast
dna double strand break processing GO:0000729 3 0.011
positive regulation of developmental process GO:0051094 143 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
regulation of mitotic sister chromatid segregation GO:0033047 28 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
regulation of mitotic spindle organization GO:0060236 9 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
regulation of nucleoside metabolic process GO:0009118 50 0.010
positive regulation of mitotic cell cycle GO:0045931 34 0.010
establishment of spindle orientation GO:0051294 18 0.010
positive regulation of catabolic process GO:0009896 105 0.010
negative regulation of cellular component organization GO:0051129 108 0.010

Mcm5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
organ system cancer DOID:0050686 0 0.031