Drosophila melanogaster

150 known processes

chico (Dmel_CG5686)

CG5686 gene product from transcript CG5686-RB

(Aliases: Dmel\CG5686,dIRS,fs(2)4,anon-WO0078940.4,IRS/chico,fs(2)ry4,BcDNA.GH11263,IRS,BcDNA:GH11263,CHICO,chic,CG5686,Chico,anon-WO0078940.1)

chico biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 332 0.995
multicellular organismal aging GO:0010259 140 0.995
regulation of growth GO:0040008 233 0.994
growth GO:0040007 359 0.979
negative regulation of signaling GO:0023057 219 0.969
Human Rat
organelle fission GO:0048285 340 0.940
regulation of developmental growth GO:0048638 174 0.938
negative regulation of cell communication GO:0010648 223 0.934
Human Rat
aging GO:0007568 143 0.931
determination of adult lifespan GO:0008340 137 0.931
regulation of protein phosphorylation GO:0001932 64 0.925
lipid metabolic process GO:0006629 121 0.908
regulation of multicellular organism growth GO:0040014 40 0.885
enzyme linked receptor protein signaling pathway GO:0007167 179 0.881
response to organic substance GO:0010033 284 0.874
regulation of cell growth GO:0001558 43 0.859
embryo development ending in birth or egg hatching GO:0009792 152 0.851
positive regulation of macromolecule metabolic process GO:0010604 405 0.839
Human
positive regulation of growth GO:0045927 75 0.833
dna metabolic process GO:0006259 227 0.830
protein phosphorylation GO:0006468 169 0.827
germarium derived egg chamber formation GO:0007293 101 0.817
regulation of cell death GO:0010941 173 0.774
Mouse
molting cycle GO:0042303 56 0.773
negative regulation of kinase activity GO:0033673 16 0.767
Mouse
brain development GO:0007420 120 0.757
Mouse
cell motility GO:0048870 251 0.752
Mouse
regulation of cell size GO:0008361 63 0.749
negative regulation of response to stimulus GO:0048585 258 0.748
Rat
regulation of autophagy GO:0010506 62 0.731
response to nitrogen compound GO:1901698 90 0.721
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.702
epithelial cell development GO:0002064 274 0.701
phosphorylation GO:0016310 294 0.691
Mouse Rat
negative regulation of cellular metabolic process GO:0031324 382 0.683
Mouse
negative regulation of nervous system development GO:0051961 92 0.675
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.668
regulation of multicellular organismal development GO:2000026 414 0.665
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.647
Human
regulation of cellular protein metabolic process GO:0032268 243 0.641
associative learning GO:0008306 65 0.641
ovarian follicle cell development GO:0030707 248 0.627
autophagy GO:0006914 108 0.621
response to oxidative stress GO:0006979 86 0.607
regulation of cell differentiation GO:0045595 302 0.601
positive regulation of cell growth GO:0030307 19 0.588
regulation of protein kinase activity GO:0045859 51 0.586
regulation of phosphorus metabolic process GO:0051174 210 0.585
Mouse Rat
regulation of nervous system development GO:0051960 248 0.583
regulation of cellular component size GO:0032535 98 0.582
protein complex biogenesis GO:0070271 201 0.530
Rat
cellular response to chemical stimulus GO:0070887 199 0.523
regulation of protein metabolic process GO:0051246 256 0.519
compound eye morphogenesis GO:0001745 249 0.516
chromosome organization GO:0051276 360 0.505
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.501
regulation of mapk cascade GO:0043408 92 0.484
cellular protein modification process GO:0006464 438 0.474
synaptic growth at neuromuscular junction GO:0051124 119 0.470
axon development GO:0061564 297 0.468
positive regulation of nucleic acid templated transcription GO:1903508 266 0.465
mitotic nuclear division GO:0007067 213 0.462
developmental growth GO:0048589 280 0.459
positive regulation of multicellular organism growth GO:0040018 21 0.459
transcription from rna polymerase ii promoter GO:0006366 368 0.455
cellular response to organonitrogen compound GO:0071417 36 0.452
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.446
Human Rat
positive regulation of cellular component organization GO:0051130 156 0.444
cell growth GO:0016049 108 0.441
regulation of cellular ketone metabolic process GO:0010565 3 0.421
Human
cellular carbohydrate metabolic process GO:0044262 22 0.420
Human
positive regulation of phosphate metabolic process GO:0045937 139 0.419
Mouse Rat
positive regulation of cellular biosynthetic process GO:0031328 316 0.415
Human
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.414
Mouse Rat
negative regulation of cell differentiation GO:0045596 143 0.402
positive regulation of developmental process GO:0051094 143 0.393
regulation of insulin receptor signaling pathway GO:0046626 17 0.390
Rat
response to bacterium GO:0009617 198 0.387
mitotic cell cycle checkpoint GO:0007093 88 0.385
regulation of kinase activity GO:0043549 53 0.384
Mouse Rat
positive regulation of protein metabolic process GO:0051247 128 0.381
catabolic process GO:0009056 409 0.369
Human Mouse
cellular response to dna damage stimulus GO:0006974 223 0.359
response to organonitrogen compound GO:0010243 75 0.357
neurological system process GO:0050877 358 0.351
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.351
positive regulation of transcription dna templated GO:0045893 266 0.344
positive regulation of multicellular organismal process GO:0051240 143 0.337
collateral sprouting GO:0048668 3 0.335
regulation of phosphorylation GO:0042325 147 0.335
Mouse Rat
cellular response to endogenous stimulus GO:0071495 80 0.330
columnar cuboidal epithelial cell development GO:0002066 249 0.330
positive regulation of rna metabolic process GO:0051254 271 0.327
chromatin organization GO:0006325 207 0.325
regulation of cellular component biogenesis GO:0044087 201 0.324
macromolecular complex assembly GO:0065003 256 0.324
Rat
multicellular organism growth GO:0035264 46 0.317
cellular response to oxygen containing compound GO:1901701 79 0.315
protein catabolic process GO:0030163 101 0.313
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.312
positive regulation of biosynthetic process GO:0009891 316 0.304
Human
mushroom body development GO:0016319 70 0.304
regulation of neuron differentiation GO:0045664 103 0.303
negative regulation of signal transduction GO:0009968 206 0.299
Rat
stress activated mapk cascade GO:0051403 52 0.299
epithelium migration GO:0090132 148 0.297
regulation of immune system process GO:0002682 176 0.294
embryonic development via the syncytial blastoderm GO:0001700 148 0.293
regulation of catabolic process GO:0009894 170 0.289
Human
learning GO:0007612 75 0.286
single organism cellular localization GO:1902580 180 0.285
positive regulation of gene expression GO:0010628 290 0.276
signal transduction by phosphorylation GO:0023014 107 0.275
tor signaling GO:0031929 32 0.274
positive regulation of rna biosynthetic process GO:1902680 266 0.274
regulation of protein modification process GO:0031399 112 0.274
response to reactive oxygen species GO:0000302 24 0.272
imaginal disc growth GO:0007446 37 0.269
regulation of anatomical structure size GO:0090066 163 0.263
mapk cascade GO:0000165 107 0.261
actin cytoskeleton organization GO:0030036 206 0.261
regulation of cellular amino acid metabolic process GO:0006521 0 0.261
metal ion transport GO:0030001 74 0.260
positive regulation of developmental growth GO:0048639 62 0.260
response to starvation GO:0042594 97 0.256
imaginal disc derived appendage morphogenesis GO:0035114 395 0.254
cellular response to organic substance GO:0071310 132 0.250
multicellular organismal reproductive behavior GO:0033057 110 0.248
negative regulation of phosphate metabolic process GO:0045936 45 0.242
Mouse
positive regulation of cell size GO:0045793 21 0.241
protein modification process GO:0036211 438 0.241
regulation of response to oxidative stress GO:1902882 4 0.237
neuron death GO:0070997 27 0.237
positive regulation of phosphorus metabolic process GO:0010562 139 0.237
Mouse Rat
regulation of apoptotic process GO:0042981 130 0.235
Mouse
negative regulation of intracellular signal transduction GO:1902532 57 0.231
central nervous system development GO:0007417 201 0.226
Mouse
purine containing compound metabolic process GO:0072521 155 0.225
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.221
activation of protein kinase activity GO:0032147 12 0.221
inositol lipid mediated signaling GO:0048017 4 0.221
Human
homeostatic process GO:0042592 199 0.218
neuron projection guidance GO:0097485 241 0.214
cellular response to hormone stimulus GO:0032870 44 0.214
regulation of proteolysis GO:0030162 87 0.210
regulation of organelle organization GO:0033043 196 0.201
cation transport GO:0006812 110 0.201
positive regulation of autophagy GO:0010508 21 0.201
negative regulation of growth GO:0045926 84 0.200
regulation of lipid metabolic process GO:0019216 15 0.198
Human Mouse Rat
gene silencing GO:0016458 138 0.198
positive regulation of phosphorylation GO:0042327 87 0.193
Mouse Rat
cellular ketone metabolic process GO:0042180 24 0.193
Human
positive regulation of signal transduction GO:0009967 223 0.193
Rat
imaginal disc derived wing morphogenesis GO:0007476 337 0.192
chemical homeostasis GO:0048878 92 0.192
cellular response to insulin stimulus GO:0032869 28 0.188
response to nutrient levels GO:0031667 114 0.188
regulation of cellular response to insulin stimulus GO:1900076 17 0.187
Human Rat
negative regulation of phosphorylation GO:0042326 35 0.186
Mouse
localization of cell GO:0051674 257 0.184
Mouse
molting cycle chitin based cuticle GO:0007591 56 0.182
golgi organization GO:0007030 66 0.181
positive regulation of cell migration GO:0030335 2 0.180
Mouse
proteolysis GO:0006508 192 0.176
regulation of jnk cascade GO:0046328 40 0.174
regionalization GO:0003002 416 0.172
rhythmic process GO:0048511 106 0.169
epithelial cell migration GO:0010631 148 0.167
regulation of stress activated mapk cascade GO:0032872 41 0.166
peptidyl amino acid modification GO:0018193 105 0.165
stress activated protein kinase signaling cascade GO:0031098 55 0.163
protein complex assembly GO:0006461 200 0.161
Rat
germarium derived female germ line cyst formation GO:0030727 42 0.161
cellular response to reactive oxygen species GO:0034614 14 0.160
regulation of macroautophagy GO:0016241 15 0.159
negative regulation of protein metabolic process GO:0051248 85 0.158
response to heat GO:0009408 63 0.156
positive regulation of signaling GO:0023056 243 0.155
Mouse Rat
regulation of cytoplasmic transport GO:1903649 47 0.155
regulation of response to stress GO:0080134 200 0.155
regulation of imaginal disc growth GO:0045570 26 0.155
activation of mapk activity GO:0000187 9 0.152
nucleotide metabolic process GO:0009117 161 0.151
cellular response to external stimulus GO:0071496 66 0.149
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.149
dna packaging GO:0006323 91 0.149
regulation of programmed cell death GO:0043067 152 0.148
Mouse
mitotic dna damage checkpoint GO:0044773 74 0.147
negative regulation of developmental process GO:0051093 201 0.147
negative regulation of developmental growth GO:0048640 64 0.146
response to temperature stimulus GO:0009266 106 0.146
developmental maturation GO:0021700 172 0.144
ameboidal type cell migration GO:0001667 151 0.142
cellular protein catabolic process GO:0044257 83 0.141
intracellular signal transduction GO:0035556 300 0.141
Human Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.141
jak stat cascade GO:0007259 49 0.140
oxoacid metabolic process GO:0043436 103 0.140
Human
regulation of intracellular signal transduction GO:1902531 236 0.140
cation homeostasis GO:0055080 51 0.139
macromolecule catabolic process GO:0009057 161 0.139
response to endogenous stimulus GO:0009719 119 0.137
response to hydrogen peroxide GO:0042542 11 0.137
negative regulation of autophagy GO:0010507 16 0.135
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.134
imaginal disc derived appendage development GO:0048737 399 0.133
cell death GO:0008219 279 0.132
Mouse
forebrain development GO:0030900 2 0.130
organ growth GO:0035265 56 0.129
immune system process GO:0002376 347 0.128
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.128
meiotic nuclear division GO:0007126 151 0.128
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.127
Rat
jnk cascade GO:0007254 50 0.126
regulation of transferase activity GO:0051338 58 0.126
Mouse Rat
cellular amine metabolic process GO:0044106 12 0.125
purine ribonucleoside metabolic process GO:0046128 127 0.125
asymmetric protein localization GO:0008105 33 0.123
negative regulation of phosphorus metabolic process GO:0010563 45 0.123
Mouse
positive regulation of protein kinase activity GO:0045860 25 0.123
positive regulation of lipid metabolic process GO:0045834 4 0.122
Human Mouse Rat
maintenance of location in cell GO:0051651 28 0.122
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.120
Human
negative regulation of programmed cell death GO:0043069 72 0.119
Mouse
metal ion homeostasis GO:0055065 44 0.119
epithelial cell differentiation GO:0030855 322 0.119
entry into diapause GO:0055115 1 0.118
neuromuscular junction development GO:0007528 149 0.118
meiotic chromosome segregation GO:0045132 59 0.118
regulation of epithelial cell proliferation GO:0050678 4 0.117
female germ line cyst formation GO:0048135 42 0.117
regulation of cell cycle GO:0051726 291 0.116
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.116
purine nucleoside triphosphate catabolic process GO:0009146 108 0.116
post embryonic appendage morphogenesis GO:0035120 385 0.116
response to oxygen containing compound GO:1901700 200 0.116
extrinsic apoptotic signaling pathway GO:0097191 1 0.114
positive regulation of mapk cascade GO:0043410 63 0.114
positive regulation of insulin receptor signaling pathway GO:0046628 3 0.114
Rat
regulation of synapse organization GO:0050807 110 0.113
chorion containing eggshell formation GO:0007304 105 0.112
wing disc morphogenesis GO:0007472 344 0.112
reproductive behavior GO:0019098 122 0.112
negative regulation of transcription dna templated GO:0045892 237 0.111
multi organism reproductive behavior GO:0044705 121 0.110
regulation of cell cycle process GO:0010564 181 0.110
negative regulation of multicellular organismal process GO:0051241 142 0.110
cellular response to oxidative stress GO:0034599 28 0.109
negative regulation of gene expression GO:0010629 387 0.106
protein localization to organelle GO:0033365 82 0.106
Mouse
cell cycle dna replication GO:0044786 23 0.105
cellular macromolecule localization GO:0070727 220 0.104
Mouse
positive regulation of protein modification process GO:0031401 58 0.103
regulation of reactive oxygen species metabolic process GO:2000377 8 0.102
endocytosis GO:0006897 310 0.101
heterochromatin organization GO:0070828 25 0.101
regulation of organ growth GO:0046620 42 0.101
spindle organization GO:0007051 253 0.101
positive regulation of cellular protein metabolic process GO:0032270 118 0.101
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.101
neural precursor cell proliferation GO:0061351 75 0.099
cell proliferation GO:0008283 299 0.099
Mouse
regulation of cell migration GO:0030334 22 0.098
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.097
small gtpase mediated signal transduction GO:0007264 88 0.094
compound eye development GO:0048749 307 0.092
response to ethanol GO:0045471 59 0.092
circadian rhythm GO:0007623 105 0.091
regulation of cell development GO:0060284 215 0.091
regulation of immune response GO:0050776 118 0.090
chromatin modification GO:0016568 147 0.090
developmental cell growth GO:0048588 52 0.089
organophosphate metabolic process GO:0019637 195 0.089
Mouse Rat
regulation of cellular response to oxidative stress GO:1900407 4 0.087
larval development GO:0002164 104 0.084
head development GO:0060322 135 0.084
Mouse
negative regulation of neurogenesis GO:0050768 53 0.083
chromatin silencing GO:0006342 76 0.083
positive regulation of cell motility GO:2000147 3 0.082
Mouse
negative regulation of protein phosphorylation GO:0001933 17 0.082
maintenance of protein location in cell GO:0032507 26 0.082
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.081
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.081
cell competition in a multicellular organism GO:0035212 10 0.081
divalent inorganic cation homeostasis GO:0072507 29 0.080
positive regulation of cell differentiation GO:0045597 64 0.079
negative regulation of cellular component organization GO:0051129 108 0.079
chromosome segregation GO:0007059 157 0.078
nucleoside catabolic process GO:0009164 112 0.078
dna endoreduplication GO:0042023 22 0.078
actin filament based process GO:0030029 220 0.077
single organism biosynthetic process GO:0044711 206 0.077
Human
autophagic vacuole assembly GO:0000045 2 0.076
small molecule metabolic process GO:0044281 305 0.076
Human
germarium derived oocyte differentiation GO:0030706 29 0.076
mitotic cell cycle phase transition GO:0044772 138 0.076
cellular protein localization GO:0034613 160 0.075
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.075
cellular lipid metabolic process GO:0044255 83 0.075
Human Mouse Rat
oocyte development GO:0048599 124 0.074
taxis GO:0042330 304 0.073
regulation of neural precursor cell proliferation GO:2000177 35 0.072
carbohydrate metabolic process GO:0005975 82 0.072
Human
cellular response to nitrogen compound GO:1901699 51 0.072
negative regulation of cellular biosynthetic process GO:0031327 277 0.072
organic acid metabolic process GO:0006082 103 0.071
Human
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.071
regulation of synapse structure and activity GO:0050803 128 0.071
maintenance of location GO:0051235 73 0.070
glycerolipid metabolic process GO:0046486 34 0.070
Mouse Rat
regulation of mitotic cell cycle GO:0007346 190 0.069
regulation of neurogenesis GO:0050767 158 0.069
cell junction organization GO:0034330 57 0.068
translation GO:0006412 69 0.068
hindbrain development GO:0030902 2 0.068
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.068
nucleobase containing small molecule metabolic process GO:0055086 174 0.068
positive regulation of nitric oxide biosynthetic process GO:0045429 1 0.068
regulation of response to nutrient levels GO:0032107 18 0.067
long term memory GO:0007616 62 0.067
regulation of phosphate metabolic process GO:0019220 210 0.067
Mouse Rat
regulation of cell motility GO:2000145 23 0.066
Mouse
regulation of localization GO:0032879 275 0.065
Human Mouse Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.065
response to biotic stimulus GO:0009607 294 0.064
negative regulation of cell development GO:0010721 62 0.064
death GO:0016265 284 0.064
Mouse
paracrine signaling GO:0038001 7 0.063
positive regulation of nervous system development GO:0051962 69 0.063
regulation of catalytic activity GO:0050790 185 0.063
Mouse Rat
mating behavior GO:0007617 106 0.062
locomotor rhythm GO:0045475 56 0.062
regulation of epithelial cell migration GO:0010632 12 0.061
cellular amino acid metabolic process GO:0006520 61 0.061
protein localization GO:0008104 284 0.061
Mouse
cellular response to heat GO:0034605 24 0.061
oocyte axis specification GO:0007309 108 0.060
innate immune response GO:0045087 144 0.060
establishment of protein localization to organelle GO:0072594 62 0.060
ribonucleoside catabolic process GO:0042454 112 0.060
histone modification GO:0016570 106 0.059
regulation of stem cell proliferation GO:0072091 40 0.059
Mouse
germarium derived oocyte fate determination GO:0007294 26 0.059
regulation of defense response GO:0031347 102 0.059
dna conformation change GO:0071103 105 0.058
positive regulation of neurogenesis GO:0050769 41 0.057
regulation of cell projection organization GO:0031344 92 0.057
oocyte maturation GO:0001556 3 0.057
digestive system development GO:0055123 149 0.056
regulation of cell substrate adhesion GO:0010810 2 0.056
carboxylic acid metabolic process GO:0019752 92 0.056
Human
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.055
organonitrogen compound metabolic process GO:1901564 318 0.055
negative regulation of transferase activity GO:0051348 18 0.055
Mouse
response to monosaccharide GO:0034284 4 0.054
Mouse
peptidyl tyrosine phosphorylation GO:0018108 24 0.053
negative regulation of apoptotic process GO:0043066 63 0.053
Mouse
regulation of photoreceptor cell differentiation GO:0046532 34 0.053
positive regulation of proteolysis GO:0045862 52 0.053
ovarian follicle cell migration GO:0007297 121 0.053
negative regulation of immune response GO:0050777 39 0.053
positive regulation of nurse cell apoptotic process GO:0045850 5 0.053
response to organic cyclic compound GO:0014070 89 0.052
Rat
regulation of nurse cell apoptotic process GO:0045477 9 0.052
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.050
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.050
positive regulation of cell development GO:0010720 61 0.050
eye morphogenesis GO:0048592 260 0.050
apoptotic process GO:0006915 159 0.050
Mouse
purine ribonucleotide metabolic process GO:0009150 145 0.050
cellular response to nutrient levels GO:0031669 62 0.050
cell cycle phase transition GO:0044770 140 0.049
cellular response to organic cyclic compound GO:0071407 32 0.049
telencephalon development GO:0021537 2 0.049
olfactory behavior GO:0042048 97 0.049
membrane organization GO:0061024 112 0.048
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 2 0.047
regulation of phosphatase activity GO:0010921 3 0.047
purine containing compound catabolic process GO:0072523 112 0.047
positive regulation of cell communication GO:0010647 250 0.046
Mouse Rat
oocyte differentiation GO:0009994 145 0.046
defense response to bacterium GO:0042742 178 0.046
cell type specific apoptotic process GO:0097285 38 0.046
Mouse
endomembrane system organization GO:0010256 119 0.045
positive regulation of neuron apoptotic process GO:0043525 1 0.045
apoptotic signaling pathway GO:0097190 27 0.045
negative regulation of epithelial cell proliferation GO:0050680 4 0.045
positive regulation of cell adhesion GO:0045785 10 0.045
behavioral response to ethanol GO:0048149 49 0.044
programmed cell death GO:0012501 257 0.044
Mouse
immune response GO:0006955 246 0.044
reactive oxygen species metabolic process GO:0072593 22 0.044
aromatic compound catabolic process GO:0019439 166 0.044
regulation of wnt signaling pathway GO:0030111 68 0.044
purine ribonucleotide catabolic process GO:0009154 109 0.044
response to hormone GO:0009725 45 0.044
positive regulation of tor signaling GO:0032008 13 0.044
positive regulation of neuron differentiation GO:0045666 26 0.044
circadian behavior GO:0048512 76 0.043
mitochondrial fission GO:0000266 8 0.043
positive regulation of response to stimulus GO:0048584 323 0.043
regulation of intracellular protein transport GO:0033157 46 0.043
heterocycle catabolic process GO:0046700 166 0.042
cell migration GO:0016477 238 0.042
Mouse
regulation of cell junction assembly GO:1901888 2 0.042
carbohydrate derivative metabolic process GO:1901135 217 0.042
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.042
negative regulation of catalytic activity GO:0043086 42 0.042
Mouse
regulation of cellular component movement GO:0051270 42 0.042
Mouse
regulation of protein complex assembly GO:0043254 42 0.041
regulation of map kinase activity GO:0043405 17 0.041
axon guidance GO:0007411 233 0.041
camera type eye morphogenesis GO:0048593 2 0.041
cellular divalent inorganic cation homeostasis GO:0072503 23 0.040
regulation of lipid kinase activity GO:0043550 2 0.040
Mouse Rat
regulation of cell matrix adhesion GO:0001952 1 0.040
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.040
ribose phosphate metabolic process GO:0019693 145 0.040
adult behavior GO:0030534 137 0.040
regulation of gliogenesis GO:0014013 11 0.040
carbohydrate derivative catabolic process GO:1901136 118 0.040
regulation of cellular response to stress GO:0080135 89 0.040
regulation of cellular localization GO:0060341 136 0.039
Human Mouse Rat
oocyte microtubule cytoskeleton organization GO:0016325 35 0.039
negative regulation of cellular protein metabolic process GO:0032269 85 0.039
regulation of system process GO:0044057 36 0.038
response to insulin GO:0032868 29 0.038
mitotic spindle organization GO:0007052 220 0.038
meiotic cell cycle GO:0051321 171 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.038
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.038
learning or memory GO:0007611 141 0.038
modification dependent protein catabolic process GO:0019941 78 0.037
negative regulation of protein modification process GO:0031400 29 0.037
cognition GO:0050890 141 0.036
hematopoietic or lymphoid organ development GO:0048534 57 0.036
cellular response to starvation GO:0009267 61 0.036
protein import into nucleus GO:0006606 51 0.035
positive regulation of organelle organization GO:0010638 65 0.035
positive regulation of kinase activity GO:0033674 25 0.035
Mouse Rat
peptidyl tyrosine modification GO:0018212 24 0.035
regeneration GO:0031099 16 0.035
regulation of molecular function GO:0065009 217 0.035
Mouse Rat
purine nucleotide catabolic process GO:0006195 109 0.034
negative regulation of neuron death GO:1901215 18 0.034
calcium ion homeostasis GO:0055074 23 0.034
positive regulation of catalytic activity GO:0043085 118 0.034
Mouse Rat
tube development GO:0035295 244 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.033
protein autophosphorylation GO:0046777 15 0.033
organic substance transport GO:0071702 257 0.033
Human Mouse Rat
cell maturation GO:0048469 144 0.033
response to axon injury GO:0048678 12 0.033
germ band shortening GO:0007390 19 0.033
organic substance catabolic process GO:1901575 308 0.033
Human Mouse
ion homeostasis GO:0050801 55 0.033
regulation of carbohydrate metabolic process GO:0006109 10 0.033
Human
glycosyl compound catabolic process GO:1901658 112 0.032
cellular response to peptide GO:1901653 28 0.032
regulation of meiosis GO:0040020 3 0.032
macroautophagy GO:0016236 42 0.032
response to extracellular stimulus GO:0009991 116 0.032
ras protein signal transduction GO:0007265 88 0.032
cellular response to ionizing radiation GO:0071479 15 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.032
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.031
chemotaxis GO:0006935 249 0.031
regulation of axon regeneration GO:0048679 4 0.031
posttranscriptional regulation of gene expression GO:0010608 145 0.031
wnt signaling pathway GO:0016055 98 0.031
regulation of nitric oxide biosynthetic process GO:0045428 1 0.031
nucleus localization GO:0051647 34 0.031
nucleoside metabolic process GO:0009116 127 0.031
amine metabolic process GO:0009308 12 0.031
cellular response to extracellular stimulus GO:0031668 64 0.030
response to oxygen levels GO:0070482 59 0.030
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.030
cellular homeostasis GO:0019725 80 0.030
negative regulation of gene expression epigenetic GO:0045814 77 0.030
cellular macromolecule catabolic process GO:0044265 136 0.030
negative regulation of cell cycle GO:0045786 116 0.030
regulation of actin filament polymerization GO:0030833 25 0.029
regulation of translation GO:0006417 56 0.029
regulation of nucleocytoplasmic transport GO:0046822 35 0.029
cellular catabolic process GO:0044248 372 0.029
Human
regulation of protein transport GO:0051223 57 0.029
regulation of nuclear division GO:0051783 58 0.029
negative regulation of mitotic cell cycle GO:0045930 109 0.029
microtubule bundle formation GO:0001578 27 0.028
positive regulation of cell death GO:0010942 69 0.028
establishment of protein localization GO:0045184 163 0.028
response to wounding GO:0009611 94 0.028
ribonucleoside triphosphate catabolic process GO:0009203 108 0.028
regulation of gene expression epigenetic GO:0040029 128 0.027
positive regulation of jun kinase activity GO:0043507 4 0.027

chico disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.035