Drosophila melanogaster

0 known processes

fz4 (Dmel_CG4626)

frizzled 4

(Aliases: DFz4,anon-WO0170980.10,Fz4,CG4626,Dmel\CG4626,anon-WO0170980.11,Dfz4)

fz4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.191
protein modification process GO:0036211 438 0.135
single organism intracellular transport GO:1902582 207 0.123
cellular catabolic process GO:0044248 372 0.098
catabolic process GO:0009056 409 0.091
intracellular transport GO:0046907 228 0.084
cellular macromolecule localization GO:0070727 220 0.083
protein transport GO:0015031 155 0.082
endomembrane system organization GO:0010256 119 0.081
endocytosis GO:0006897 310 0.076
Human Fly
cellular protein modification process GO:0006464 438 0.076
response to organic substance GO:0010033 284 0.067
Rat
vesicle mediated transport GO:0016192 381 0.067
Human Fly
single organism cellular localization GO:1902580 180 0.065
detection of stimulus GO:0051606 156 0.059
regulation of protein metabolic process GO:0051246 256 0.059
protein localization GO:0008104 284 0.056
cell proliferation GO:0008283 299 0.056
Human Rat Fly
organic substance transport GO:0071702 257 0.055
regulation of intracellular signal transduction GO:1902531 236 0.055
Rat
appendage development GO:0048736 401 0.054
Fly
organonitrogen compound metabolic process GO:1901564 318 0.053
cellular protein localization GO:0034613 160 0.053
cellular lipid metabolic process GO:0044255 83 0.052
cytoplasmic transport GO:0016482 130 0.052
response to oxygen containing compound GO:1901700 200 0.050
Rat
localization of cell GO:0051674 257 0.048
Fly
establishment of protein localization GO:0045184 163 0.048
developmental growth GO:0048589 280 0.046
Fly
lipid metabolic process GO:0006629 121 0.046
eye morphogenesis GO:0048592 260 0.046
Fly
positive regulation of cell communication GO:0010647 250 0.045
Human
regulation of localization GO:0032879 275 0.045
Human
carbohydrate derivative metabolic process GO:1901135 217 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.043
regulation of cellular component biogenesis GO:0044087 201 0.041
Fly
single organism biosynthetic process GO:0044711 206 0.041
organelle localization GO:0051640 148 0.041
lipid biosynthetic process GO:0008610 46 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.040
death GO:0016265 284 0.040
Human
post embryonic appendage morphogenesis GO:0035120 385 0.039
Fly
phosphorylation GO:0016310 294 0.039
Rat
small molecule metabolic process GO:0044281 305 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.038
organic substance catabolic process GO:1901575 308 0.038
regulation of cell development GO:0060284 215 0.037
Mouse
phagocytosis GO:0006909 215 0.037
enzyme linked receptor protein signaling pathway GO:0007167 179 0.037
regionalization GO:0003002 416 0.036
Fly
cell death GO:0008219 279 0.036
Human
regulation of vesicle mediated transport GO:0060627 59 0.036
Human
peptidyl amino acid modification GO:0018193 105 0.036
cell recognition GO:0008037 102 0.035
Fly
regulation of endocytosis GO:0030100 37 0.035
Human
intracellular protein transport GO:0006886 104 0.035
cellular response to chemical stimulus GO:0070887 199 0.035
cholesterol transport GO:0030301 2 0.034
tube development GO:0035295 244 0.034
digestive system development GO:0055123 149 0.034
ribose phosphate metabolic process GO:0019693 145 0.033
positive regulation of gene expression GO:0010628 290 0.033
Human
response to lipopolysaccharide GO:0032496 4 0.033
eye development GO:0001654 323 0.033
Fly
membrane organization GO:0061024 112 0.033
appendage morphogenesis GO:0035107 397 0.033
Fly
intracellular signal transduction GO:0035556 300 0.033
Rat
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
wing disc morphogenesis GO:0007472 344 0.032
Fly
response to biotic stimulus GO:0009607 294 0.031
homeostatic process GO:0042592 199 0.031
Human
chromosome organization GO:0051276 360 0.031
sensory organ morphogenesis GO:0090596 260 0.031
Mouse Fly
positive regulation of cellular component organization GO:0051130 156 0.031
Human
regulation of cell differentiation GO:0045595 302 0.030
Human Mouse
regulation of cellular component size GO:0032535 98 0.030
single organism catabolic process GO:0044712 228 0.029
actin cytoskeleton organization GO:0030036 206 0.029
Fly
response to other organism GO:0051707 293 0.029
cellular response to organic substance GO:0071310 132 0.029
response to extracellular stimulus GO:0009991 116 0.028
actin filament based process GO:0030029 220 0.028
Fly
purine nucleotide metabolic process GO:0006163 146 0.028
embryonic morphogenesis GO:0048598 206 0.028
Mouse
compound eye morphogenesis GO:0001745 249 0.028
Fly
regulation of transport GO:0051049 181 0.028
Human
regulation of organelle organization GO:0033043 196 0.027
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
Fly
response to radiation GO:0009314 155 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
secretion GO:0046903 109 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
immune system process GO:0002376 347 0.026
Fly
positive regulation of response to stimulus GO:0048584 323 0.026
Human
positive regulation of multicellular organismal process GO:0051240 143 0.026
Human
regulation of cell size GO:0008361 63 0.026
regulation of anatomical structure size GO:0090066 163 0.026
Fly
response to organonitrogen compound GO:0010243 75 0.025
Rat
regulation of immune system process GO:0002682 176 0.025
Fly
defense response GO:0006952 300 0.025
single organism membrane organization GO:0044802 93 0.025
response to external biotic stimulus GO:0043207 293 0.025
transmembrane transport GO:0055085 139 0.025
regulation of growth GO:0040008 233 0.024
Human
neurological system process GO:0050877 358 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.024
detection of light stimulus GO:0009583 58 0.024
regulation of catabolic process GO:0009894 170 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
synaptic transmission GO:0007268 288 0.024
immune effector process GO:0002252 98 0.023
digestive tract morphogenesis GO:0048546 127 0.023
protein modification by small protein conjugation or removal GO:0070647 106 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
Human Mouse
regulation of cell morphogenesis GO:0022604 163 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
purine containing compound metabolic process GO:0072521 155 0.023
purine nucleoside metabolic process GO:0042278 127 0.023
cellular response to abiotic stimulus GO:0071214 58 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
negative regulation of gene expression GO:0010629 387 0.023
exocrine system development GO:0035272 162 0.023
Fly
regulation of nervous system development GO:0051960 248 0.023
protein modification by small protein conjugation GO:0032446 79 0.022
positive regulation of signal transduction GO:0009967 223 0.022
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
Fly
phototransduction GO:0007602 52 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
ethanolamine containing compound metabolic process GO:0042439 4 0.022
camera type eye development GO:0043010 4 0.022
taxis GO:0042330 304 0.022
Fly
regulation of apoptotic process GO:0042981 130 0.022
Human
organic cyclic compound catabolic process GO:1901361 168 0.022
apoptotic process GO:0006915 159 0.022
Human
regulation of neurogenesis GO:0050767 158 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
nucleotide metabolic process GO:0009117 161 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
Rat
regulation of phosphate metabolic process GO:0019220 210 0.021
Rat
regulation of cell projection organization GO:0031344 92 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
androgen metabolic process GO:0008209 1 0.021
cellular ketone metabolic process GO:0042180 24 0.021
golgi organization GO:0007030 66 0.021
single organism behavior GO:0044708 391 0.020
compound eye development GO:0048749 307 0.020
Fly
regulation of molecular function GO:0065009 217 0.020
Human
purine ribonucleoside metabolic process GO:0046128 127 0.020
glycoprotein metabolic process GO:0009100 41 0.020
response to abiotic stimulus GO:0009628 341 0.020
salivary gland development GO:0007431 162 0.020
Fly
growth GO:0040007 359 0.020
Human Fly
cell growth GO:0016049 108 0.020
Human Fly
positive regulation of signaling GO:0023056 243 0.020
Human
macromolecule catabolic process GO:0009057 161 0.020
cell motility GO:0048870 251 0.020
Fly
polyol biosynthetic process GO:0046173 3 0.019
protein complex disassembly GO:0043241 36 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
dna metabolic process GO:0006259 227 0.019
response to bacterium GO:0009617 198 0.019
nucleoside catabolic process GO:0009164 112 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
nuclear division GO:0000280 332 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
nucleocytoplasmic transport GO:0006913 72 0.019
negative regulation of signaling GO:0023057 219 0.019
Human Mouse Rat Fly
actin filament organization GO:0007015 126 0.019
Fly
mapk cascade GO:0000165 107 0.019
Rat
regulation of cellular amine metabolic process GO:0033238 3 0.019
golgi vesicle transport GO:0048193 27 0.019
heterocycle catabolic process GO:0046700 166 0.019
positive regulation of molecular function GO:0044093 136 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
Fly
organophosphate metabolic process GO:0019637 195 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
cell migration GO:0016477 238 0.018
Fly
regulation of programmed cell death GO:0043067 152 0.018
Human
cellular amino acid metabolic process GO:0006520 61 0.018
imaginal disc pattern formation GO:0007447 91 0.018
regulation of cell proliferation GO:0042127 163 0.018
Human Rat Fly
purine containing compound catabolic process GO:0072523 112 0.018
detection of external stimulus GO:0009581 66 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
regulation of cytoskeleton organization GO:0051493 89 0.018
Fly
segmentation GO:0035282 207 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
axon development GO:0061564 297 0.017
Fly
digestive tract development GO:0048565 149 0.017
microtubule polymerization or depolymerization GO:0031109 39 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
response to nitrogen compound GO:1901698 90 0.017
Rat
nucleoside phosphate catabolic process GO:1901292 110 0.017
response to temperature stimulus GO:0009266 106 0.017
mitotic nuclear division GO:0007067 213 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
oligosaccharide biosynthetic process GO:0009312 10 0.017
gastrulation GO:0007369 70 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
nuclear transport GO:0051169 72 0.017
lateral inhibition GO:0046331 206 0.017
aromatic compound catabolic process GO:0019439 166 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
cellular response to oxygen containing compound GO:1901701 79 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
tetraterpenoid metabolic process GO:0016108 1 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
ras protein signal transduction GO:0007265 88 0.016
carotenoid metabolic process GO:0016116 1 0.016
nitrogen compound transport GO:0071705 85 0.016
organophosphate catabolic process GO:0046434 112 0.016
gland morphogenesis GO:0022612 145 0.016
Rat Fly
photoreceptor cell differentiation GO:0046530 170 0.016
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.016
positive regulation of transport GO:0051050 92 0.016
Human
isoprenoid transport GO:0046864 2 0.016
cellular protein complex disassembly GO:0043624 35 0.016
organic acid metabolic process GO:0006082 103 0.015
secretion by cell GO:0032940 101 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
defense response to other organism GO:0098542 225 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
nucleotide catabolic process GO:0009166 109 0.015
positive regulation of lipid storage GO:0010884 4 0.015
axonogenesis GO:0007409 290 0.015
Fly
negative regulation of response to stimulus GO:0048585 258 0.015
Human Mouse Rat Fly
positive regulation of cell motility GO:2000147 3 0.015
proteolysis GO:0006508 192 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
regulation of cell cycle GO:0051726 291 0.015
rna localization GO:0006403 115 0.015
negative regulation of signal transduction GO:0009968 206 0.015
Human Mouse Rat Fly
memory GO:0007613 94 0.015
ion transport GO:0006811 145 0.015
Human
multi organism behavior GO:0051705 175 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of immune response GO:0050776 118 0.015
ribonucleotide catabolic process GO:0009261 109 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
response to nutrient levels GO:0031667 114 0.014
dendrite morphogenesis GO:0048813 199 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
response to light stimulus GO:0009416 124 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
Fly
notch signaling pathway GO:0007219 120 0.014
Fly
negative regulation of cytoskeleton organization GO:0051494 30 0.014
regulation of cellular localization GO:0060341 136 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
amine metabolic process GO:0009308 12 0.014
open tracheal system development GO:0007424 204 0.014
Fly
positive regulation of cellular catabolic process GO:0031331 95 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
Fly
cellular amine metabolic process GO:0044106 12 0.014
negative regulation of cell communication GO:0010648 223 0.014
Human Mouse Rat Fly
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
nucleoside metabolic process GO:0009116 127 0.014
body morphogenesis GO:0010171 2 0.014
salivary gland morphogenesis GO:0007435 145 0.014
Fly
axon guidance GO:0007411 233 0.014
Fly
positive regulation of catalytic activity GO:0043085 118 0.014
leg disc development GO:0035218 92 0.014
cell adhesion GO:0007155 136 0.014
Fly
nucleoside triphosphate catabolic process GO:0009143 108 0.014
oocyte dorsal ventral axis specification GO:0007310 34 0.014
cell aging GO:0007569 2 0.014
dendrite development GO:0016358 204 0.013
positive regulation of cell migration GO:0030335 2 0.013
reproductive behavior GO:0019098 122 0.013
response to endogenous stimulus GO:0009719 119 0.013
Rat
muscle organ development GO:0007517 127 0.013
neuron projection guidance GO:0097485 241 0.013
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
humoral immune response GO:0006959 117 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.013
regulation of neuron projection development GO:0010975 69 0.013
protein complex biogenesis GO:0070271 201 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
small molecule biosynthetic process GO:0044283 37 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
retina development in camera type eye GO:0060041 4 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
multi multicellular organism process GO:0044706 123 0.013
Rat
regulation of developmental growth GO:0048638 174 0.013
organelle fission GO:0048285 340 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
Fly
tissue morphogenesis GO:0048729 297 0.013
Mouse Fly
response to organophosphorus GO:0046683 2 0.013
chemotaxis GO:0006935 249 0.013
Fly
positive regulation of phosphorylation GO:0042327 87 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
Human
epithelial cell development GO:0002064 274 0.012
Fly
positive regulation of organelle organization GO:0010638 65 0.012
positive regulation of cell death GO:0010942 69 0.012
Human
establishment of organelle localization GO:0051656 122 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
positive regulation of catabolic process GO:0009896 105 0.012
anatomical structure homeostasis GO:0060249 97 0.012
mating behavior GO:0007617 106 0.012
regulation of phosphorylation GO:0042325 147 0.012
Rat
response to organic cyclic compound GO:0014070 89 0.012
Rat
protein localization to organelle GO:0033365 82 0.012
glycoprotein biosynthetic process GO:0009101 41 0.012
multicellular organismal aging GO:0010259 140 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
protein maturation GO:0051604 71 0.012
aging GO:0007568 143 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
gland development GO:0048732 191 0.012
Mouse Rat Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
cellular response to light stimulus GO:0071482 37 0.012
tissue migration GO:0090130 155 0.012
Fly
response to alcohol GO:0097305 95 0.012
Rat
regulation of neuron differentiation GO:0045664 103 0.012
macromolecular complex assembly GO:0065003 256 0.012
cell projection assembly GO:0030031 94 0.012
protein ubiquitination GO:0016567 70 0.012
developmental programmed cell death GO:0010623 138 0.012
dorsal ventral axis specification GO:0009950 66 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
macromolecular complex disassembly GO:0032984 37 0.012
negative regulation of organelle organization GO:0010639 56 0.012
sister chromatid segregation GO:0000819 92 0.012
protein depolymerization GO:0051261 31 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.011
defense response to bacterium GO:0042742 178 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
Rat
central nervous system development GO:0007417 201 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
cellular response to uv GO:0034644 12 0.011
oxoacid metabolic process GO:0043436 103 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
regulation of lipid metabolic process GO:0019216 15 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
leg disc morphogenesis GO:0007478 80 0.011
formation of primary germ layer GO:0001704 24 0.011
protein alkylation GO:0008213 43 0.011
regulation of cell shape GO:0008360 113 0.011
autophagic cell death GO:0048102 83 0.011
glycerolipid metabolic process GO:0046486 34 0.011
wing disc pattern formation GO:0035222 66 0.011
negative regulation of developmental process GO:0051093 201 0.011
Mouse
carbohydrate metabolic process GO:0005975 82 0.011
positive regulation of cell development GO:0010720 61 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of hormone levels GO:0010817 40 0.011
lipid localization GO:0010876 54 0.011
muscle structure development GO:0061061 224 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
Mouse
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
biological adhesion GO:0022610 138 0.011
Fly
organophosphate biosynthetic process GO:0090407 46 0.011
regulation of cell death GO:0010941 173 0.011
Human
axis specification GO:0009798 167 0.011
cellular response to biotic stimulus GO:0071216 4 0.010
protein processing GO:0016485 68 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
gtp catabolic process GO:0006184 72 0.010
aggressive behavior GO:0002118 63 0.010
methylation GO:0032259 47 0.010
ketone biosynthetic process GO:0042181 16 0.010
negative regulation of cellular biosynthetic process GO:0031327 277 0.010
cation transport GO:0006812 110 0.010
carbohydrate biosynthetic process GO:0016051 17 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
Mouse Fly
rho protein signal transduction GO:0007266 14 0.010
chromosome segregation GO:0007059 157 0.010
larval development GO:0002164 104 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
respiratory system development GO:0060541 213 0.010
Fly
anion homeostasis GO:0055081 3 0.010
Human
maintenance of location GO:0051235 73 0.010
positive regulation of lipid metabolic process GO:0045834 4 0.010
regulation of proteolysis GO:0030162 87 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
Fly
camera type eye morphogenesis GO:0048593 2 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
Fly
regulation of intracellular protein transport GO:0033157 46 0.010

fz4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011