Drosophila melanogaster

70 known processes

Eaf (Dmel_CG11166)

ELL-associated factor

(Aliases: LD35207,dEaf,EP(2)2475,CG1706,Dmel\CG11166,CG11166)

Eaf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 401 0.283
appendage morphogenesis GO:0035107 397 0.204
wing disc morphogenesis GO:0007472 344 0.182
post embryonic appendage morphogenesis GO:0035120 385 0.168
imaginal disc derived wing morphogenesis GO:0007476 337 0.139
imaginal disc derived appendage development GO:0048737 399 0.133
negative regulation of multicellular organismal process GO:0051241 142 0.111
learning or memory GO:0007611 141 0.111
protein ubiquitination GO:0016567 70 0.109
regulation of cell development GO:0060284 215 0.098
forebrain development GO:0030900 2 0.096
protein modification by small protein conjugation or removal GO:0070647 106 0.088
neurological system process GO:0050877 358 0.085
cellular protein modification process GO:0006464 438 0.083
negative regulation of developmental process GO:0051093 201 0.081
regulation of cellular component biogenesis GO:0044087 201 0.076
ameboidal type cell migration GO:0001667 151 0.076
eye photoreceptor cell differentiation GO:0001754 145 0.070
protein modification by small protein conjugation GO:0032446 79 0.069
negative regulation of signaling GO:0023057 219 0.068
regulation of nervous system development GO:0051960 248 0.066
eye development GO:0001654 323 0.062
regulation of cellular protein metabolic process GO:0032268 243 0.058
negative regulation of cell communication GO:0010648 223 0.057
long term memory GO:0007616 62 0.057
enzyme linked receptor protein signaling pathway GO:0007167 179 0.056
cellular macromolecular complex assembly GO:0034622 153 0.055
eye morphogenesis GO:0048592 260 0.055
compound eye development GO:0048749 307 0.053
tube development GO:0035295 244 0.053
regulation of protein metabolic process GO:0051246 256 0.053
negative regulation of gene expression GO:0010629 387 0.052
organonitrogen compound metabolic process GO:1901564 318 0.052
purine nucleoside triphosphate metabolic process GO:0009144 119 0.051
negative regulation of response to stimulus GO:0048585 258 0.050
establishment of organelle localization GO:0051656 122 0.049
regulation of cellular ketone metabolic process GO:0010565 3 0.049
positive regulation of rna metabolic process GO:0051254 271 0.048
regulation of organelle organization GO:0033043 196 0.048
cell migration GO:0016477 238 0.048
immune system process GO:0002376 347 0.048
epithelial cell development GO:0002064 274 0.047
localization of cell GO:0051674 257 0.046
establishment of localization in cell GO:0051649 402 0.046
embryonic hindgut morphogenesis GO:0048619 48 0.046
carboxylic acid metabolic process GO:0019752 92 0.045
positive regulation of cellular component biogenesis GO:0044089 80 0.044
regulation of transport GO:0051049 181 0.043
intracellular signal transduction GO:0035556 300 0.043
ribose phosphate metabolic process GO:0019693 145 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
negative regulation of signal transduction GO:0009968 206 0.042
immune effector process GO:0002252 98 0.041
positive regulation of signal transduction GO:0009967 223 0.041
purine ribonucleoside metabolic process GO:0046128 127 0.041
regulation of phosphorus metabolic process GO:0051174 210 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
regulation of neuron differentiation GO:0045664 103 0.040
defense response GO:0006952 300 0.040
autophagy GO:0006914 108 0.039
organic acid metabolic process GO:0006082 103 0.039
vesicle mediated transport GO:0016192 381 0.038
regulation of neurogenesis GO:0050767 158 0.037
regulation of localization GO:0032879 275 0.037
embryonic pattern specification GO:0009880 174 0.036
heterocycle catabolic process GO:0046700 166 0.035
cellular amide metabolic process GO:0043603 80 0.035
positive regulation of gene expression GO:0010628 290 0.035
lateral inhibition GO:0046331 206 0.034
single organism behavior GO:0044708 391 0.034
cell motility GO:0048870 251 0.034
positive regulation of rna biosynthetic process GO:1902680 266 0.032
carbohydrate derivative metabolic process GO:1901135 217 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
transcription from rna polymerase ii promoter GO:0006366 368 0.031
negative regulation of nervous system development GO:0051961 92 0.031
regulation of intracellular signal transduction GO:1902531 236 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
camera type eye development GO:0043010 4 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
central nervous system development GO:0007417 201 0.031
cellular response to oxygen containing compound GO:1901701 79 0.031
compound eye morphogenesis GO:0001745 249 0.030
tissue migration GO:0090130 155 0.030
regulation of response to stress GO:0080134 200 0.030
multicellular organism growth GO:0035264 46 0.030
rhythmic process GO:0048511 106 0.030
cellular catabolic process GO:0044248 372 0.029
connective tissue development GO:0061448 3 0.029
cognition GO:0050890 141 0.029
sensory organ morphogenesis GO:0090596 260 0.029
olfactory learning GO:0008355 56 0.029
macromolecular complex assembly GO:0065003 256 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.029
actin cytoskeleton organization GO:0030036 206 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.028
nucleoside triphosphate metabolic process GO:0009141 120 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
oxoacid metabolic process GO:0043436 103 0.028
telencephalon development GO:0021537 2 0.027
endomembrane system organization GO:0010256 119 0.027
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.027
regulation of immune system process GO:0002682 176 0.027
photoreceptor cell differentiation GO:0046530 170 0.027
protein modification process GO:0036211 438 0.027
intracellular transport GO:0046907 228 0.027
small molecule metabolic process GO:0044281 305 0.027
epidermal growth factor receptor signaling pathway GO:0007173 58 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
associative learning GO:0008306 65 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
regulation of anatomical structure size GO:0090066 163 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.025
single organism biosynthetic process GO:0044711 206 0.025
body morphogenesis GO:0010171 2 0.025
negative regulation of cell differentiation GO:0045596 143 0.025
tissue morphogenesis GO:0048729 297 0.024
adult behavior GO:0030534 137 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.024
phosphorylation GO:0016310 294 0.024
blastoderm segmentation GO:0007350 159 0.024
gland development GO:0048732 191 0.024
aromatic compound catabolic process GO:0019439 166 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
epithelium migration GO:0090132 148 0.023
actin filament based process GO:0030029 220 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
protein complex biogenesis GO:0070271 201 0.023
regulation of steroid metabolic process GO:0019218 2 0.023
memory GO:0007613 94 0.023
single organism intracellular transport GO:1902582 207 0.023
cellular amine metabolic process GO:0044106 12 0.023
regionalization GO:0003002 416 0.022
epithelial cell migration GO:0010631 148 0.022
compound eye photoreceptor cell differentiation GO:0001751 140 0.022
organelle localization GO:0051640 148 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
dna metabolic process GO:0006259 227 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
positive regulation of signaling GO:0023056 243 0.022
head development GO:0060322 135 0.022
imaginal disc pattern formation GO:0007447 91 0.021
oocyte dorsal ventral axis specification GO:0007310 34 0.021
stem cell differentiation GO:0048863 117 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
cytoplasmic transport GO:0016482 130 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
rna localization GO:0006403 115 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
cell proliferation GO:0008283 299 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
response to abiotic stimulus GO:0009628 341 0.021
notch signaling pathway GO:0007219 120 0.020
inter male aggressive behavior GO:0002121 60 0.020
anterior posterior pattern specification GO:0009952 136 0.020
gene silencing GO:0016458 138 0.020
purine containing compound metabolic process GO:0072521 155 0.020
tube morphogenesis GO:0035239 191 0.020
positive regulation of catabolic process GO:0009896 105 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.020
phagocytosis GO:0006909 215 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
regulation of synapse assembly GO:0051963 94 0.020
endocytosis GO:0006897 310 0.020
erbb signaling pathway GO:0038127 58 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
purine nucleotide metabolic process GO:0006163 146 0.019
vesicle organization GO:0016050 44 0.019
amine metabolic process GO:0009308 12 0.019
regulation of gene silencing GO:0060968 63 0.019
immune response GO:0006955 246 0.019
pigmentation GO:0043473 75 0.019
chromatin organization GO:0006325 207 0.019
negative regulation of growth GO:0045926 84 0.019
taxis GO:0042330 304 0.019
developmental programmed cell death GO:0010623 138 0.019
regulation of multi organism process GO:0043900 131 0.019
growth GO:0040007 359 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
nucleoside metabolic process GO:0009116 127 0.018
hindbrain development GO:0030902 2 0.018
synaptic transmission GO:0007268 288 0.018
positive regulation of protein metabolic process GO:0051247 128 0.018
positive regulation of cell communication GO:0010647 250 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
urogenital system development GO:0001655 72 0.017
imaginal disc derived leg morphogenesis GO:0007480 80 0.017
positive regulation of developmental process GO:0051094 143 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.017
cellular response to organic substance GO:0071310 132 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
nucleotide metabolic process GO:0009117 161 0.017
protein localization GO:0008104 284 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
photoreceptor cell fate commitment GO:0046552 41 0.017
respiratory system development GO:0060541 213 0.017
purine ribonucleotide catabolic process GO:0009154 109 0.017
organic substance transport GO:0071702 257 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
regulation of response to external stimulus GO:0032101 115 0.017
regulation of purine nucleotide catabolic process GO:0033121 48 0.017
epithelial tube morphogenesis GO:0060562 88 0.016
regulation of cellular localization GO:0060341 136 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
regulation of catalytic activity GO:0050790 185 0.016
regulation of growth GO:0040008 233 0.016
cellular protein localization GO:0034613 160 0.016
locomotory behavior GO:0007626 176 0.016
cellular ketone metabolic process GO:0042180 24 0.016
negative regulation of cell development GO:0010721 62 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
gtp catabolic process GO:0006184 72 0.016
retina development in camera type eye GO:0060041 4 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
developmental growth GO:0048589 280 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
organophosphate catabolic process GO:0046434 112 0.016
wing disc pattern formation GO:0035222 66 0.016
organophosphate metabolic process GO:0019637 195 0.016
negative regulation of neurogenesis GO:0050768 53 0.015
positive regulation of transport GO:0051050 92 0.015
actin filament organization GO:0007015 126 0.015
regulation of synapse organization GO:0050807 110 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
response to monosaccharide GO:0034284 4 0.015
male gamete generation GO:0048232 201 0.015
cellular macromolecule localization GO:0070727 220 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
developmental pigmentation GO:0048066 68 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
cellular homeostasis GO:0019725 80 0.015
nucleotide catabolic process GO:0009166 109 0.015
learning GO:0007612 75 0.015
regulation of catabolic process GO:0009894 170 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
stem cell development GO:0048864 79 0.015
nucleoside catabolic process GO:0009164 112 0.015
regulation of ion transport GO:0043269 39 0.015
gtp metabolic process GO:0046039 72 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
axis specification GO:0009798 167 0.014
purine containing compound catabolic process GO:0072523 112 0.014
embryonic organ development GO:0048568 50 0.014
androgen metabolic process GO:0008209 1 0.014
cell death GO:0008219 279 0.014
axon development GO:0061564 297 0.014
leg disc morphogenesis GO:0007478 80 0.014
regulation of hydrolase activity GO:0051336 97 0.014
catabolic process GO:0009056 409 0.014
aging GO:0007568 143 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
olfactory behavior GO:0042048 97 0.014
chemosensory behavior GO:0007635 106 0.014
germarium derived egg chamber formation GO:0007293 101 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
response to other organism GO:0051707 293 0.014
lipid storage GO:0019915 38 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
negative regulation of transcription dna templated GO:0045892 237 0.013
regulation of immune effector process GO:0002697 52 0.013
segmentation GO:0035282 207 0.013
negative regulation of developmental growth GO:0048640 64 0.013
regulation of cell proliferation GO:0042127 163 0.013
regulation of cell projection organization GO:0031344 92 0.013
border follicle cell migration GO:0007298 113 0.013
response to external biotic stimulus GO:0043207 293 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
regulation of actin filament based process GO:0032970 42 0.013
establishment of protein localization GO:0045184 163 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
response to biotic stimulus GO:0009607 294 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
developmental maturation GO:0021700 172 0.013
regulation of behavior GO:0050795 75 0.013
secretion GO:0046903 109 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
negative regulation of gene expression epigenetic GO:0045814 77 0.013
response to organic substance GO:0010033 284 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
regulation of cell cycle GO:0051726 291 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
chromatin silencing GO:0006342 76 0.012
decapentaplegic signaling pathway GO:0008101 19 0.012
eye photoreceptor cell development GO:0042462 81 0.012
wing disc dorsal ventral pattern formation GO:0048190 47 0.012
morphogenesis of a branching epithelium GO:0061138 45 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
detection of stimulus involved in sensory perception GO:0050906 92 0.012
protein complex assembly GO:0006461 200 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
maintenance of location GO:0051235 73 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
response to oxygen containing compound GO:1901700 200 0.012
death GO:0016265 284 0.012
regulation of erbb signaling pathway GO:1901184 42 0.012
homeostatic process GO:0042592 199 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
jak stat cascade GO:0007259 49 0.012
organic substance catabolic process GO:1901575 308 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
dendrite development GO:0016358 204 0.012
production of molecular mediator of immune response GO:0002440 46 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.011
embryonic morphogenesis GO:0048598 206 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
chemotaxis GO:0006935 249 0.011
positive regulation of secretion GO:0051047 22 0.011
single organism cellular localization GO:1902580 180 0.011
compound eye photoreceptor fate commitment GO:0001752 36 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
compound eye photoreceptor development GO:0042051 78 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
quinone metabolic process GO:1901661 1 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of secretion GO:0051046 44 0.011
translation GO:0006412 69 0.011
regulation of developmental growth GO:0048638 174 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
macromolecule catabolic process GO:0009057 161 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
digestive tract development GO:0048565 149 0.011
regulation of cellular component size GO:0032535 98 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
gliogenesis GO:0042063 80 0.011
positive regulation of cell development GO:0010720 61 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
positive regulation of cell migration GO:0030335 2 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
response to glucose GO:0009749 2 0.010
photoreceptor cell development GO:0042461 96 0.010
secretory granule organization GO:0033363 6 0.010
kidney development GO:0001822 3 0.010
cell maturation GO:0048469 144 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
response to peptide hormone GO:0043434 29 0.010
dna damage checkpoint GO:0000077 78 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
rna transport GO:0050658 46 0.010
protein transport GO:0015031 155 0.010
circadian rhythm GO:0007623 105 0.010
brain development GO:0007420 120 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of humoral immune response GO:0002920 51 0.010
dendrite morphogenesis GO:0048813 199 0.010
mitotic spindle organization GO:0007052 220 0.010
chromosome organization GO:0051276 360 0.010
mrna metabolic process GO:0016071 124 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010

Eaf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
nervous system disease DOID:863 0 0.015
organ system cancer DOID:0050686 0 0.012