Drosophila melanogaster

114 known processes

sty (Dmel_CG1921)

sprouty

(Aliases: Dmel\CG1921,dSPRY,spry,Spry,CG1921,CS3-3,Sry,Sty)

sty biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
compound eye photoreceptor fate commitment GO:0001752 36 0.993
r7 cell differentiation GO:0045466 43 0.993
eye photoreceptor cell fate commitment GO:0042706 37 0.989
eye photoreceptor cell differentiation GO:0001754 145 0.986
eye morphogenesis GO:0048592 260 0.985
branching involved in open tracheal system development GO:0060446 45 0.984
compound eye photoreceptor cell differentiation GO:0001751 140 0.974
epithelial cell migration GO:0010631 148 0.974
sensory organ morphogenesis GO:0090596 260 0.972
photoreceptor cell differentiation GO:0046530 170 0.967
compound eye morphogenesis GO:0001745 249 0.965
compound eye development GO:0048749 307 0.960
open tracheal system development GO:0007424 204 0.954
associative learning GO:0008306 65 0.946
negative regulation of gene expression GO:0010629 387 0.935
establishment of ommatidial planar polarity GO:0042067 49 0.933
eye development GO:0001654 323 0.885
positive regulation of r7 cell differentiation GO:0045678 7 0.882
negative regulation of cellular biosynthetic process GO:0031327 277 0.881
photoreceptor cell fate commitment GO:0046552 41 0.879
negative regulation of cellular metabolic process GO:0031324 382 0.874
Human Mouse
epithelium migration GO:0090132 148 0.872
axon development GO:0061564 297 0.868
negative regulation of rna biosynthetic process GO:1902679 240 0.841
regulation of r7 cell differentiation GO:0045676 15 0.830
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.819
eggshell chorion assembly GO:0007306 66 0.803
ovarian follicle cell development GO:0030707 248 0.782
chorion containing eggshell formation GO:0007304 105 0.778
negative regulation of transcription dna templated GO:0045892 237 0.777
negative regulation of nucleic acid templated transcription GO:1903507 240 0.768
erbb signaling pathway GO:0038127 58 0.739
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.735
regulation of endopeptidase activity GO:0052548 36 0.731
compound eye cone cell fate commitment GO:0042676 5 0.727
r7 cell fate commitment GO:0007465 12 0.726
cell fate specification GO:0001708 71 0.722
striated muscle cell development GO:0055002 50 0.719
epidermal growth factor receptor signaling pathway GO:0007173 58 0.718
epithelial cell development GO:0002064 274 0.711
establishment or maintenance of cell polarity GO:0007163 167 0.711
positive regulation of rna metabolic process GO:0051254 271 0.706
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.691
Mouse
gliogenesis GO:0042063 80 0.690
negative regulation of biosynthetic process GO:0009890 277 0.686
transcription from rna polymerase ii promoter GO:0006366 368 0.680
positive regulation of transcription dna templated GO:0045893 266 0.674
central nervous system development GO:0007417 201 0.650
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.646
ameboidal type cell migration GO:0001667 151 0.639
dendrite development GO:0016358 204 0.638
positive regulation of macromolecule metabolic process GO:0010604 405 0.636
Human
cell cell signaling involved in cell fate commitment GO:0045168 210 0.622
Mouse
axonogenesis GO:0007409 290 0.608
growth GO:0040007 359 0.608
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.596
negative regulation of response to stimulus GO:0048585 258 0.595
regulation of cell differentiation GO:0045595 302 0.593
eggshell formation GO:0030703 105 0.574
response to gravity GO:0009629 26 0.568
regulation of phosphate metabolic process GO:0019220 210 0.558
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.545
compound eye cone cell differentiation GO:0042675 13 0.543
branching morphogenesis of an epithelial tube GO:0048754 45 0.539
respiratory system development GO:0060541 213 0.532
myotube cell development GO:0014904 3 0.530
Zebrafish
programmed cell death GO:0012501 257 0.529
Human Mouse
synaptic transmission GO:0007268 288 0.526
cell migration GO:0016477 238 0.512
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.511
Mouse
establishment of tissue polarity GO:0007164 87 0.500
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.471
response to abiotic stimulus GO:0009628 341 0.471
regulation of neurogenesis GO:0050767 158 0.459
negative regulation of cell communication GO:0010648 223 0.456
positive regulation of nucleic acid templated transcription GO:1903508 266 0.455
regulation of proteolysis GO:0030162 87 0.453
columnar cuboidal epithelial cell development GO:0002066 249 0.452
regulation of multicellular organismal development GO:2000026 414 0.439
negative regulation of signaling GO:0023057 219 0.432
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.430
tracheal outgrowth open tracheal system GO:0007426 18 0.420
regulation of anatomical structure morphogenesis GO:0022603 242 0.415
embryonic morphogenesis GO:0048598 206 0.414
Mouse
morphogenesis of an epithelium GO:0002009 276 0.399
regulation of programmed cell death GO:0043067 152 0.395
Human Mouse
autophagy GO:0006914 108 0.394
macromolecular complex assembly GO:0065003 256 0.390
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.387
sex differentiation GO:0007548 81 0.386
cellular component assembly involved in morphogenesis GO:0010927 151 0.384
muscle fiber development GO:0048747 12 0.371
muscle organ development GO:0007517 127 0.371
Zebrafish
r3 r4 cell differentiation GO:0048056 12 0.363
lateral inhibition GO:0046331 206 0.360
learning GO:0007612 75 0.358
regulation of cell death GO:0010941 173 0.354
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.350
negative regulation of rna metabolic process GO:0051253 251 0.346
regulation of nervous system development GO:0051960 248 0.345
negative regulation of developmental process GO:0051093 201 0.343
epithelial cell migration open tracheal system GO:0007427 32 0.341
tissue migration GO:0090130 155 0.339
small gtpase mediated signal transduction GO:0007264 88 0.337
Mouse
regulation of erbb signaling pathway GO:1901184 42 0.337
cell death GO:0008219 279 0.333
Human Mouse
skeletal muscle organ development GO:0060538 48 0.328
Zebrafish
death GO:0016265 284 0.324
Human Mouse
neuron fate commitment GO:0048663 50 0.323
morphogenesis of a polarized epithelium GO:0001738 93 0.320
head development GO:0060322 135 0.317
Zebrafish
regulation of organ growth GO:0046620 42 0.316
axon guidance GO:0007411 233 0.314
r3 r4 cell fate commitment GO:0007464 10 0.306
camera type eye development GO:0043010 4 0.304
striated muscle tissue development GO:0014706 27 0.300
Zebrafish
learning or memory GO:0007611 141 0.293
taxis GO:0042330 304 0.293
regulation of cellular protein metabolic process GO:0032268 243 0.287
Human Mouse
apoptotic process GO:0006915 159 0.281
Human Mouse
regulation of cell development GO:0060284 215 0.278
brain development GO:0007420 120 0.277
Zebrafish
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.277
tube morphogenesis GO:0035239 191 0.275
epithelial cell type specification open tracheal system GO:0035153 11 0.273
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.270
retina development in camera type eye GO:0060041 4 0.267
cell division GO:0051301 248 0.267
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.265
regulation of neuron differentiation GO:0045664 103 0.261
cellular response to growth factor stimulus GO:0071363 30 0.260
cellular protein modification process GO:0006464 438 0.259
Human Mouse
negative regulation of kinase activity GO:0033673 16 0.254
Mouse
epithelial cell differentiation GO:0030855 322 0.253
adherens junction assembly GO:0034333 11 0.253
negative regulation of apoptotic process GO:0043066 63 0.250
Human Mouse
regulation of protein metabolic process GO:0051246 256 0.248
Human Mouse
fusion cell fate specification GO:0035156 4 0.244
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.235
enzyme linked receptor protein signaling pathway GO:0007167 179 0.235
regulation of cell fate commitment GO:0010453 29 0.233
appendage development GO:0048736 401 0.233
developmental growth involved in morphogenesis GO:0060560 65 0.232
Mouse
sensory perception of mechanical stimulus GO:0050954 72 0.231
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.227
regulation of organ morphogenesis GO:2000027 78 0.226
negative regulation of cell fate specification GO:0009996 15 0.225
cognition GO:0050890 141 0.225
response to alcohol GO:0097305 95 0.220
response to transforming growth factor beta GO:0071559 18 0.219
regulation of cell proliferation GO:0042127 163 0.215
Mouse
immune response GO:0006955 246 0.215
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.202
stem cell development GO:0048864 79 0.191
negative regulation of cell differentiation GO:0045596 143 0.189
tissue morphogenesis GO:0048729 297 0.186
adult behavior GO:0030534 137 0.181
cell motility GO:0048870 251 0.176
imaginal disc derived appendage development GO:0048737 399 0.174
regulation of cell fate specification GO:0042659 27 0.171
purine ribonucleoside catabolic process GO:0046130 112 0.169
Mouse
striated muscle cell differentiation GO:0051146 90 0.166
positive regulation of biosynthetic process GO:0009891 316 0.166
positive regulation of multicellular organismal process GO:0051240 143 0.164
Mouse
regulation of system process GO:0044057 36 0.162
imaginal disc growth GO:0007446 37 0.162
compound eye photoreceptor development GO:0042051 78 0.160
epithelial tube morphogenesis GO:0060562 88 0.160
neuron projection guidance GO:0097485 241 0.156
small molecule metabolic process GO:0044281 305 0.156
Mouse
ensheathment of neurons GO:0007272 10 0.155
actin cytoskeleton organization GO:0030036 206 0.151
negative regulation of multicellular organismal process GO:0051241 142 0.150
muscle structure development GO:0061061 224 0.146
organic acid metabolic process GO:0006082 103 0.146
imaginal disc derived appendage morphogenesis GO:0035114 395 0.145
epithelial cell proliferation GO:0050673 15 0.145
regulation of peptidase activity GO:0052547 39 0.144
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.144
compound eye retinal cell programmed cell death GO:0046667 23 0.144
morphogenesis of a branching epithelium GO:0061138 45 0.142
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.141
oxoacid metabolic process GO:0043436 103 0.141
negative regulation of neurogenesis GO:0050768 53 0.139
imaginal disc derived wing vein specification GO:0007474 48 0.136
ras protein signal transduction GO:0007265 88 0.135
Mouse
olfactory learning GO:0008355 56 0.134
regulation of cell morphogenesis GO:0022604 163 0.133
negative regulation of protein phosphorylation GO:0001933 17 0.132
Human Mouse
dorsal appendage formation GO:0046843 47 0.128
border follicle cell migration GO:0007298 113 0.127
peptidyl amino acid modification GO:0018193 105 0.127
Human
actin filament based process GO:0030029 220 0.126
erk1 and erk2 cascade GO:0070371 39 0.126
Human Mouse
dendrite morphogenesis GO:0048813 199 0.125
positive regulation of developmental process GO:0051094 143 0.125
Mouse
positive regulation of neurogenesis GO:0050769 41 0.123
signal transduction by phosphorylation GO:0023014 107 0.123
Human Mouse
mapk cascade GO:0000165 107 0.119
Human Mouse
positive regulation of nervous system development GO:0051962 69 0.118
muscle tissue development GO:0060537 30 0.115
Zebrafish
protein modification process GO:0036211 438 0.115
Human Mouse
cell junction assembly GO:0034329 42 0.114
heart development GO:0007507 82 0.113
negative regulation of cell cycle GO:0045786 116 0.113
negative regulation of epithelial cell proliferation GO:0050680 4 0.112
negative regulation of cellular protein metabolic process GO:0032269 85 0.109
Human Mouse
heart process GO:0003015 37 0.107
stem cell differentiation GO:0048863 117 0.107
cellular amino acid metabolic process GO:0006520 61 0.106
response to radiation GO:0009314 155 0.105
regionalization GO:0003002 416 0.105
Mouse
neurological system process GO:0050877 358 0.103
Mouse
morphogenesis of a branching structure GO:0001763 45 0.102
protein modification by small protein conjugation or removal GO:0070647 106 0.102
chemotaxis GO:0006935 249 0.101
regulation of cell shape GO:0008360 113 0.101
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.100
renal tubule morphogenesis GO:0061333 44 0.100
synaptic growth at neuromuscular junction GO:0051124 119 0.099
tube development GO:0035295 244 0.098
phosphorylation GO:0016310 294 0.098
Human Mouse
ribonucleoside metabolic process GO:0009119 127 0.095
Mouse
forebrain development GO:0030900 2 0.094
protein complex biogenesis GO:0070271 201 0.094
single organism cell adhesion GO:0098602 47 0.094
single organism biosynthetic process GO:0044711 206 0.092
regulation of cellular response to growth factor stimulus GO:0090287 13 0.091
regulation of membrane potential GO:0042391 35 0.090
intracellular signal transduction GO:0035556 300 0.089
Human Mouse
hindbrain development GO:0030902 2 0.087
Zebrafish
chromosome organization GO:0051276 360 0.085
response to nutrient levels GO:0031667 114 0.085
endodermal cell fate commitment GO:0001711 3 0.083
regulation of cellular catabolic process GO:0031329 157 0.083
Mouse
organ growth GO:0035265 56 0.083
Mouse
positive regulation of endopeptidase activity GO:0010950 26 0.083
renal tubule development GO:0061326 64 0.082
neuronal action potential GO:0019228 10 0.081
regulation of epithelial cell migration GO:0010632 12 0.081
glial cell development GO:0021782 27 0.079
establishment of planar polarity GO:0001736 87 0.078
regulation of phosphorus metabolic process GO:0051174 210 0.078
Human Mouse
larval visceral muscle development GO:0007523 9 0.077
negative regulation of cell death GO:0060548 81 0.077
Human Mouse
regulation of map kinase activity GO:0043405 17 0.077
Mouse
reproductive structure development GO:0048608 74 0.076
synapse assembly GO:0007416 143 0.072
nephrocyte diaphragm assembly GO:0036059 3 0.072
negative regulation of protein metabolic process GO:0051248 85 0.071
Human Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.071
Human
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.071
regulation of gene expression epigenetic GO:0040029 128 0.069
adherens junction organization GO:0034332 27 0.069
developmental growth GO:0048589 280 0.068
Mouse
negative regulation of hormone biosynthetic process GO:0032353 1 0.068
cranial nerve development GO:0021545 1 0.068
contractile actin filament bundle assembly GO:0030038 1 0.067
neural retina development GO:0003407 4 0.067
nephrocyte differentiation GO:0061319 12 0.066
axon ensheathment GO:0008366 10 0.066
peripheral nervous system development GO:0007422 52 0.064
proteolysis GO:0006508 192 0.064
locomotory behavior GO:0007626 176 0.063
immune system process GO:0002376 347 0.063
Zebrafish
branch fusion open tracheal system GO:0035147 17 0.062
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.061
mesoderm development GO:0007498 78 0.061
negative regulation of programmed cell death GO:0043069 72 0.061
Human Mouse
positive regulation of phosphorylation GO:0042327 87 0.060
Human
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.060
Human
cell junction organization GO:0034330 57 0.059
negative regulation of cell fate commitment GO:0010454 17 0.059
regulation of molecular function GO:0065009 217 0.059
Human Mouse
notch signaling pathway GO:0007219 120 0.058
regulation of cell cycle GO:0051726 291 0.057
positive regulation of growth GO:0045927 75 0.057
wound healing GO:0042060 75 0.056
cellular response to nutrient levels GO:0031669 62 0.056
cell cell junction organization GO:0045216 55 0.056
apoptotic signaling pathway GO:0097190 27 0.056
malpighian tubule development GO:0072002 64 0.055
neuromuscular synaptic transmission GO:0007274 67 0.055
regulation of phosphorylation GO:0042325 147 0.055
Human Mouse
positive regulation of gene expression GO:0010628 290 0.054
Human
organophosphate metabolic process GO:0019637 195 0.054
Mouse
response to decreased oxygen levels GO:0036293 58 0.054
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.054
response to other organism GO:0051707 293 0.053
peptidyl tyrosine phosphorylation GO:0018108 24 0.052
chromatin organization GO:0006325 207 0.052
regulation of embryonic development GO:0045995 68 0.052
negative regulation of erbb signaling pathway GO:1901185 29 0.052
detection of light stimulus GO:0009583 58 0.052
posttranscriptional regulation of gene expression GO:0010608 145 0.052
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.051
response to organic substance GO:0010033 284 0.050
positive regulation of neuron differentiation GO:0045666 26 0.049
eye photoreceptor cell development GO:0042462 81 0.049
response to biotic stimulus GO:0009607 294 0.047
positive regulation of histone deacetylation GO:0031065 2 0.047
retinal cell programmed cell death GO:0046666 25 0.045
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.045
response to mechanical stimulus GO:0009612 28 0.045
cell maturation GO:0048469 144 0.045
positive regulation of peptidase activity GO:0010952 29 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.044
gravitaxis GO:0042332 26 0.044
cellular macromolecular complex assembly GO:0034622 153 0.044
protein complex assembly GO:0006461 200 0.043
axon choice point recognition GO:0016198 26 0.043
positive regulation of cell development GO:0010720 61 0.043
regulation of catabolic process GO:0009894 170 0.042
Mouse
oocyte development GO:0048599 124 0.042
positive regulation of cell migration GO:0030335 2 0.042
activation of protein kinase activity GO:0032147 12 0.042
malpighian tubule morphogenesis GO:0007443 44 0.042
positive regulation of catalytic activity GO:0043085 118 0.041
Human
positive regulation of cell motility GO:2000147 3 0.041
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.041
dna metabolic process GO:0006259 227 0.041
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.040
organelle fission GO:0048285 340 0.039
mitotic nuclear division GO:0007067 213 0.039
regulation of hydrolase activity GO:0051336 97 0.039
Mouse
somatic muscle development GO:0007525 66 0.038
protein modification by small protein conjugation GO:0032446 79 0.037
heterocycle catabolic process GO:0046700 166 0.037
Mouse
protein localization GO:0008104 284 0.037
organic substance transport GO:0071702 257 0.037
response to oxidative stress GO:0006979 86 0.037
regulation of protein kinase activity GO:0045859 51 0.036
Human Mouse
negative regulation of dna endoreduplication GO:0032876 2 0.035
regulation of translation GO:0006417 56 0.035
adult chitin based cuticle pattern formation GO:0035018 1 0.035
regulation of wnt signaling pathway GO:0030111 68 0.035
transmission of nerve impulse GO:0019226 12 0.034
positive regulation of signal transduction GO:0009967 223 0.034
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.034
actin polymerization or depolymerization GO:0008154 31 0.034
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.034
regulation of protein deacetylation GO:0090311 2 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.034
negative regulation of retinal cell programmed cell death GO:0046671 7 0.033
nuclear body organization GO:0030575 6 0.033
digestive system development GO:0055123 149 0.032
single organismal cell cell adhesion GO:0016337 45 0.032
cell cell junction assembly GO:0007043 38 0.032
appendage morphogenesis GO:0035107 397 0.032
regulation of protein serine threonine kinase activity GO:0071900 25 0.031
Human Mouse
action potential GO:0001508 13 0.031
oocyte differentiation GO:0009994 145 0.031
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.030
peptidyl tyrosine modification GO:0018212 24 0.030
stem cell maintenance GO:0019827 67 0.030
negative regulation of protein modification process GO:0031400 29 0.030
Human Mouse
regulation of photoreceptor cell differentiation GO:0046532 34 0.030
neuromuscular junction development GO:0007528 149 0.029
negative regulation of cell cycle process GO:0010948 109 0.029
developmental maturation GO:0021700 172 0.029
mrna splicing via spliceosome GO:0000398 73 0.029
regulation of mapk cascade GO:0043408 92 0.029
Human Mouse
positive regulation of molecular function GO:0044093 136 0.029
Human
regulation of imaginal disc growth GO:0045570 26 0.028
regulation of compound eye cone cell fate specification GO:0042682 4 0.028
conditioned taste aversion GO:0001661 3 0.028
skeletal muscle tissue development GO:0007519 13 0.028
Zebrafish
nucleobase metabolic process GO:0009112 6 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.027
Human
protein maturation GO:0051604 71 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
Mouse
negative regulation of catalytic activity GO:0043086 42 0.027
Mouse
actin filament organization GO:0007015 126 0.027
positive regulation of protein modification process GO:0031401 58 0.027
Human
circulatory system development GO:0072359 82 0.027
synaptic vesicle localization GO:0097479 53 0.026
gonad development GO:0008406 50 0.026
regulation of protein export from nucleus GO:0046825 3 0.026
nuclear division GO:0000280 332 0.026
muscle cell differentiation GO:0042692 103 0.026
regulation of growth GO:0040008 233 0.025
mrna processing GO:0006397 104 0.025
cell type specific apoptotic process GO:0097285 38 0.025
catabolic process GO:0009056 409 0.025
Mouse
protein ubiquitination GO:0016567 70 0.025
dorsal ventral pattern formation GO:0009953 133 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
response to hormone GO:0009725 45 0.025
regulation of erk1 and erk2 cascade GO:0070372 39 0.025
Human Mouse
intracellular protein transport GO:0006886 104 0.025
development of primary sexual characteristics GO:0045137 50 0.024
wing disc morphogenesis GO:0007472 344 0.024
positive regulation of protein metabolic process GO:0051247 128 0.024
Human
negative regulation of autophagy GO:0010507 16 0.024
translation GO:0006412 69 0.024
divalent inorganic cation transport GO:0072511 30 0.024
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
Mouse
negative regulation of immune system process GO:0002683 50 0.024
regulation of organelle organization GO:0033043 196 0.024
gland development GO:0048732 191 0.024
regulation of actin polymerization or depolymerization GO:0008064 27 0.024
ovarian follicle cell migration GO:0007297 121 0.024
positive regulation of protein deacetylation GO:0090312 2 0.024
regulation of histone deacetylation GO:0031063 2 0.023
cellular component disassembly GO:0022411 46 0.023
visceral muscle development GO:0007522 14 0.023
cellular macromolecule localization GO:0070727 220 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.023
axon midline choice point recognition GO:0016199 26 0.023
localization of cell GO:0051674 257 0.023
regulation of catalytic activity GO:0050790 185 0.023
Human Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.023
ommatidial rotation GO:0016318 20 0.023
regulation of neuron projection development GO:0010975 69 0.023
morphogenesis of follicular epithelium GO:0016333 36 0.023
negative regulation of catabolic process GO:0009895 36 0.023
Mouse
axon ensheathment in central nervous system GO:0032291 3 0.023
rna splicing via transesterification reactions GO:0000375 73 0.023
cardiovascular system development GO:0072358 82 0.022
peptidyl lysine acetylation GO:0018394 39 0.022
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.022
cellular response to decreased oxygen levels GO:0036294 30 0.022
circulatory system process GO:0003013 37 0.022
regulation of muscle organ development GO:0048634 13 0.022
single organism behavior GO:0044708 391 0.022
eye antennal disc morphogenesis GO:0007455 34 0.022
macroautophagy GO:0016236 42 0.022
negative regulation of intracellular signal transduction GO:1902532 57 0.022
Mouse
torc1 signaling GO:0038202 12 0.022
negative regulation of fusion cell fate specification GO:0035157 2 0.021
nerve development GO:0021675 6 0.021
negative regulation of phosphate metabolic process GO:0045936 45 0.021
Human Mouse
regulation of protein localization to nucleus GO:1900180 29 0.021
rna splicing GO:0008380 83 0.021
amine metabolic process GO:0009308 12 0.021
regulation of protein modification process GO:0031399 112 0.021
Human Mouse
protein acetylation GO:0006473 39 0.021
hemocyte differentiation GO:0042386 38 0.021
synapse organization GO:0050808 196 0.020
germ line stem cell maintenance GO:0030718 50 0.020
embryonic pattern specification GO:0009880 174 0.020
regulation of phosphatase activity GO:0010921 3 0.020
histone acetylation GO:0016573 38 0.020
regulation of cellular component size GO:0032535 98 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.020
regulation of apoptotic process GO:0042981 130 0.020
Human Mouse
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.020
bmp signaling pathway GO:0030509 27 0.020
genital disc development GO:0035215 44 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.019
regulation of autophagy GO:0010506 62 0.019
positive regulation of cell death GO:0010942 69 0.019
negative regulation of insulin secretion GO:0046676 1 0.019
protein acylation GO:0043543 42 0.019
cellular homeostasis GO:0019725 80 0.019
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
Mouse
cellular protein complex assembly GO:0043623 71 0.018
negative regulation of cell development GO:0010721 62 0.018
negative regulation of phosphorus metabolic process GO:0010563 45 0.018
Human Mouse
negative regulation of nervous system development GO:0051961 92 0.018
hemocyte migration GO:0035099 19 0.018
negative regulation of multi organism process GO:0043901 29 0.018
rna processing GO:0006396 147 0.018
positive regulation of mapk cascade GO:0043410 63 0.018
Human
multicellular organismal signaling GO:0035637 12 0.018
regulation of cell motility GO:2000145 23 0.017
regulation of cell migration GO:0030334 22 0.017
sensory perception GO:0007600 196 0.017
Mouse
oocyte maturation GO:0001556 3 0.017
renal system development GO:0072001 72 0.017
Mouse
glial cell migration GO:0008347 31 0.017
ectodermal placode morphogenesis GO:0071697 4 0.017
myoblast fusion GO:0007520 43 0.017
cell proliferation GO:0008283 299 0.017
Mouse
positive regulation of locomotion GO:0040017 8 0.017
protein deacetylation GO:0006476 9 0.017
body morphogenesis GO:0010171 2 0.017
muscle cell development GO:0055001 50 0.016
regulation of kinase activity GO:0043549 53 0.016
Human Mouse
positive regulation of hydrolase activity GO:0051345 78 0.016
regulation of hemocyte differentiation GO:0045610 22 0.016
ribonucleoprotein complex disassembly GO:0032988 1 0.016
substrate dependent cell migration cell extension GO:0006930 3 0.016
embryonic hemopoiesis GO:0035162 26 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.016
endoderm formation GO:0001706 3 0.016
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.016
Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
Human
neuromuscular process GO:0050905 21 0.016
activation of mapk activity GO:0000187 9 0.016

sty disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.499
cardiovascular system disease DOID:1287 0 0.499
vascular disease DOID:178 0 0.133
musculoskeletal system disease DOID:17 0 0.022
heart conduction disease DOID:10273 0 0.020