Drosophila melanogaster

101 known processes

PGRP-SA (Dmel_CG11709)

Peptidoglycan recognition protein SA

(Aliases: CG11709,seml,SEMMELWEIS,Dm PGRP-SA,BcDNA:AT30827,Dmel\CG11709,SA)

PGRP-SA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 1.000
defense response to gram positive bacterium GO:0050830 41 0.984
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.984
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.972
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.970
Fly
immune response GO:0006955 246 0.966
antibacterial humoral response GO:0019731 44 0.952
regulation of defense response GO:0031347 102 0.951
defense response GO:0006952 300 0.951
immune system process GO:0002376 347 0.946
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.943
immune response activating signal transduction GO:0002757 2 0.937
Fly
positive regulation of antibacterial peptide production GO:0002803 20 0.930
antifungal humoral response GO:0019732 12 0.929
immune response regulating signaling pathway GO:0002764 2 0.928
Fly
defense response to bacterium GO:0042742 178 0.923
innate immune response activating signal transduction GO:0002758 2 0.918
Fly
humoral immune response GO:0006959 117 0.914
defense response to other organism GO:0098542 225 0.910
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.910
defense response to fungus GO:0050832 48 0.907
innate immune response GO:0045087 144 0.904
Fly
regulation of melanization defense response GO:0035007 6 0.903
Fly
peptidoglycan catabolic process GO:0009253 3 0.889
Fly
regulation of defense response to bacterium GO:1900424 30 0.881
positive regulation of antimicrobial peptide production GO:0002225 28 0.881
negative regulation of defense response to bacterium GO:1900425 7 0.878
Fly
response to fungus GO:0009620 50 0.869
glycosaminoglycan catabolic process GO:0006027 3 0.864
Fly
response to external biotic stimulus GO:0043207 293 0.858
activation of innate immune response GO:0002218 4 0.848
Fly
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.845
Fly
defense response to virus GO:0051607 23 0.838
Fly
antimicrobial humoral response GO:0019730 99 0.833
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.822
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.822
Fly
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.821
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.801
Fly
response to biotic stimulus GO:0009607 294 0.801
production of molecular mediator of immune response GO:0002440 46 0.799
melanin metabolic process GO:0006582 47 0.796
Fly
positive regulation of defense response to bacterium GO:1900426 23 0.787
positive regulation of humoral immune response GO:0002922 28 0.786
antibacterial peptide production GO:0002778 22 0.785
positive regulation of antimicrobial humoral response GO:0002760 28 0.777
regulation of secondary metabolic process GO:0043455 7 0.772
Fly
antimicrobial peptide production GO:0002775 46 0.767
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.748
antibacterial peptide biosynthetic process GO:0002780 22 0.748
regulation of immune response GO:0050776 118 0.728
regulation of immune system process GO:0002682 176 0.689
peptide metabolic process GO:0006518 80 0.685
regulation of innate immune response GO:0045088 71 0.680
Fly
melanization defense response GO:0035006 45 0.676
Fly
cellular amide metabolic process GO:0043603 80 0.675
glycosaminoglycan metabolic process GO:0030203 11 0.650
Fly
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.644
Fly
positive regulation of response to biotic stimulus GO:0002833 31 0.635
amide biosynthetic process GO:0043604 42 0.634
positive regulation of cellular amide metabolic process GO:0034250 26 0.632
positive regulation of immune response GO:0050778 63 0.619
defense response to gram negative bacterium GO:0050829 94 0.618
Fly
regulation of response to biotic stimulus GO:0002831 63 0.614
response to other organism GO:0051707 293 0.613
regulation of antibacterial peptide production GO:0002786 22 0.610
peptidoglycan metabolic process GO:0000270 3 0.608
Fly
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.595
response to bacterium GO:0009617 198 0.586
regulation of multi organism process GO:0043900 131 0.577
regulation of humoral immune response GO:0002920 51 0.565
positive regulation of defense response GO:0031349 59 0.552
antimicrobial peptide biosynthetic process GO:0002777 38 0.547
regulation of antimicrobial peptide production GO:0002784 44 0.535
immune effector process GO:0002252 98 0.515
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.503
positive regulation of multi organism process GO:0043902 40 0.502
regulation of cellular amide metabolic process GO:0034248 39 0.496
regulation of antimicrobial humoral response GO:0002759 50 0.493
positive regulation of response to external stimulus GO:0032103 44 0.472
aminoglycan metabolic process GO:0006022 18 0.465
Fly
regulation of response to external stimulus GO:0032101 115 0.460
aminoglycan catabolic process GO:0006026 6 0.446
Fly
peptide biosynthetic process GO:0043043 42 0.415
regulation of response to stress GO:0080134 200 0.398
regulation of production of molecular mediator of immune response GO:0002700 44 0.398
response to peptidoglycan GO:0032494 2 0.372
hemolymph coagulation GO:0042381 10 0.337
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.333
organonitrogen compound metabolic process GO:1901564 318 0.331
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.303
Fly
toll signaling pathway GO:0008063 25 0.300
positive regulation of response to stimulus GO:0048584 323 0.299
negative regulation of immune system process GO:0002683 50 0.289
Fly
positive regulation of melanization defense response GO:0035008 1 0.273
positive regulation of immune system process GO:0002684 68 0.269
secondary metabolic process GO:0019748 75 0.247
Fly
response to virus GO:0009615 28 0.246
Fly
positive regulation of immune effector process GO:0002699 28 0.238
negative regulation of cell communication GO:0010648 223 0.229
Fly
negative regulation of signal transduction GO:0009968 206 0.193
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.183
Fly
phosphorylation GO:0016310 294 0.181
Fly
phenol containing compound metabolic process GO:0018958 57 0.180
Fly
dorsal ventral axis specification GO:0009950 66 0.176
organic hydroxy compound metabolic process GO:1901615 83 0.173
Fly
negative regulation of defense response GO:0031348 35 0.169
Fly
carbohydrate derivative catabolic process GO:1901136 118 0.164
Fly
negative regulation of response to external stimulus GO:0032102 22 0.162
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.154
zymogen activation GO:0031638 20 0.152
positive regulation of biosynthetic process GO:0009891 316 0.152
organonitrogen compound biosynthetic process GO:1901566 117 0.142
carbohydrate derivative metabolic process GO:1901135 217 0.139
Fly
pigment metabolic process GO:0042440 84 0.133
Fly
response to wounding GO:0009611 94 0.129
regulation of immune effector process GO:0002697 52 0.126
negative regulation of signaling GO:0023057 219 0.124
Fly
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.116
Fly
activation of immune response GO:0002253 5 0.113
Fly
axis specification GO:0009798 167 0.112
intracellular signal transduction GO:0035556 300 0.105
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.104
Fly
positive regulation of innate immune response GO:0045089 38 0.104
Fly
jnk cascade GO:0007254 50 0.102
Fly
stress activated mapk cascade GO:0051403 52 0.100
Fly
regionalization GO:0003002 416 0.096
negative regulation of response to stimulus GO:0048585 258 0.095
Fly
protein maturation GO:0051604 71 0.093
negative regulation of innate immune response GO:0045824 30 0.093
Fly
organonitrogen compound catabolic process GO:1901565 128 0.090
Fly
wound healing GO:0042060 75 0.089
regulation of phosphorylation GO:0042325 147 0.085
Fly
negative regulation of phosphorylation GO:0042326 35 0.082
Fly
dorsal ventral pattern formation GO:0009953 133 0.071
regulation of jnk cascade GO:0046328 40 0.071
Fly
cellular response to lipid GO:0071396 20 0.070
Fly
response to lipopolysaccharide GO:0032496 4 0.069
Fly
macromolecule catabolic process GO:0009057 161 0.069
Fly
vesicle mediated transport GO:0016192 381 0.066
regulation of stress activated mapk cascade GO:0032872 41 0.066
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.064
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.061
Fly
stress activated protein kinase signaling cascade GO:0031098 55 0.060
Fly
regulation of intracellular signal transduction GO:1902531 236 0.058
Fly
appendage morphogenesis GO:0035107 397 0.058
regulation of mapk cascade GO:0043408 92 0.058
Fly
regulation of toll signaling pathway GO:0008592 17 0.057
mapk cascade GO:0000165 107 0.056
Fly
cytolysis GO:0019835 1 0.056
post embryonic appendage morphogenesis GO:0035120 385 0.052
catabolic process GO:0009056 409 0.051
Fly
negative regulation of intracellular signal transduction GO:1902532 57 0.051
Fly
endocytosis GO:0006897 310 0.049
positive regulation of signaling GO:0023056 243 0.048
negative regulation of mapk cascade GO:0043409 23 0.048
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.047
aging GO:0007568 143 0.046
Fly
cellular response to biotic stimulus GO:0071216 4 0.046
Fly
positive regulation of cell communication GO:0010647 250 0.046
protein processing GO:0016485 68 0.045
imaginal disc derived appendage development GO:0048737 399 0.045
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.045
Fly
positive regulation of signal transduction GO:0009967 223 0.044
small molecule metabolic process GO:0044281 305 0.043
wing disc morphogenesis GO:0007472 344 0.043
developmental growth GO:0048589 280 0.042
response to molecule of bacterial origin GO:0002237 7 0.042
negative regulation of phosphate metabolic process GO:0045936 45 0.042
Fly
amino sugar metabolic process GO:0006040 10 0.039
protein modification process GO:0036211 438 0.038
glucosamine containing compound catabolic process GO:1901072 3 0.038
phagocytosis GO:0006909 215 0.037
proteolysis GO:0006508 192 0.035
melanotic encapsulation of foreign target GO:0035011 30 0.035
negative regulation of response to biotic stimulus GO:0002832 12 0.035
Fly
negative regulation of protein metabolic process GO:0051248 85 0.034
appendage development GO:0048736 401 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
response to nitrogen compound GO:1901698 90 0.031
organic substance catabolic process GO:1901575 308 0.031
Fly
response to organonitrogen compound GO:0010243 75 0.031
cellular protein modification process GO:0006464 438 0.029
response to organic substance GO:0010033 284 0.029
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.029
cellular response to oxygen containing compound GO:1901701 79 0.029
Fly
determination of adult lifespan GO:0008340 137 0.029
Fly
regulation of phosphate metabolic process GO:0019220 210 0.028
Fly
organophosphate metabolic process GO:0019637 195 0.027
compound eye development GO:0048749 307 0.026
negative regulation of phosphorus metabolic process GO:0010563 45 0.026
Fly
response to oxygen containing compound GO:1901700 200 0.025
negative regulation of gene expression GO:0010629 387 0.024
homeostatic process GO:0042592 199 0.024
response to endogenous stimulus GO:0009719 119 0.023
negative regulation of multi organism process GO:0043901 29 0.022
Fly
wnt signaling pathway GO:0016055 98 0.022
eye development GO:0001654 323 0.022
cellular catabolic process GO:0044248 372 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
body morphogenesis GO:0010171 2 0.020
nuclear division GO:0000280 332 0.020
regulation of proteolysis GO:0030162 87 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
positive regulation of cell migration GO:0030335 2 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
Fly
negative regulation of peptide hormone processing GO:0060570 1 0.020
single organism catabolic process GO:0044712 228 0.020
growth GO:0040007 359 0.019
cell adhesion GO:0007155 136 0.019
actin filament based process GO:0030029 220 0.019
negative regulation of immune response GO:0050777 39 0.019
Fly
epithelial cell development GO:0002064 274 0.019
response to organophosphorus GO:0046683 2 0.018
coagulation GO:0050817 10 0.018
multicellular organismal aging GO:0010259 140 0.018
Fly
aromatic compound catabolic process GO:0019439 166 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
regulation of protein metabolic process GO:0051246 256 0.018
segmentation GO:0035282 207 0.017
chemotaxis GO:0006935 249 0.017
regulation of cellular response to stress GO:0080135 89 0.017
Fly
cation homeostasis GO:0055080 51 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
regulation of molecular function GO:0065009 217 0.017
cellular response to nutrient levels GO:0031669 62 0.017
regulation of body fluid levels GO:0050878 14 0.017
single organism cell adhesion GO:0098602 47 0.016
regulation of cell cycle GO:0051726 291 0.016
chitin catabolic process GO:0006032 3 0.016
organic acid metabolic process GO:0006082 103 0.016
connective tissue development GO:0061448 3 0.016
mitotic spindle organization GO:0007052 220 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
Fly
epithelium migration GO:0090132 148 0.015
regulation of growth GO:0040008 233 0.015
oxoacid metabolic process GO:0043436 103 0.015
negative regulation of stress activated mapk cascade GO:0032873 19 0.015
Fly
retina development in camera type eye GO:0060041 4 0.015
negative regulation of molecular function GO:0044092 51 0.015
amino sugar catabolic process GO:0046348 3 0.015
ameboidal type cell migration GO:0001667 151 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
negative regulation of catalytic activity GO:0043086 42 0.015
cellular amino acid metabolic process GO:0006520 61 0.014
single organismal cell cell adhesion GO:0016337 45 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
organelle fission GO:0048285 340 0.014
ovarian follicle cell migration GO:0007297 121 0.014
negative regulation of developmental process GO:0051093 201 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
protein localization GO:0008104 284 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
blastoderm segmentation GO:0007350 159 0.014
sensory organ morphogenesis GO:0090596 260 0.014
cellular homeostasis GO:0019725 80 0.013
embryonic pattern specification GO:0009880 174 0.013
tissue migration GO:0090130 155 0.013
regulation of protein modification process GO:0031399 112 0.013
protein phosphorylation GO:0006468 169 0.013
gene silencing by rna GO:0031047 57 0.013
developmental maturation GO:0021700 172 0.013
nucleoside metabolic process GO:0009116 127 0.013
carboxylic acid metabolic process GO:0019752 92 0.012
amine metabolic process GO:0009308 12 0.012
ovarian follicle cell development GO:0030707 248 0.012
spindle organization GO:0007051 253 0.012
response to starvation GO:0042594 97 0.012
cellular ketone metabolic process GO:0042180 24 0.012
cellular response to starvation GO:0009267 61 0.012
cellular amine metabolic process GO:0044106 12 0.012
endomembrane system organization GO:0010256 119 0.012
response to extracellular stimulus GO:0009991 116 0.012
mitotic nuclear division GO:0007067 213 0.012
epithelial cell migration GO:0010631 148 0.012
forebrain development GO:0030900 2 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
organelle assembly GO:0070925 198 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
response to lipid GO:0033993 38 0.011
Fly
regulation of catabolic process GO:0009894 170 0.011
biological adhesion GO:0022610 138 0.011
detection of chemical stimulus GO:0009593 93 0.011
anatomical structure homeostasis GO:0060249 97 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
positive regulation of cell motility GO:2000147 3 0.011
salivary gland development GO:0007431 162 0.011
regulation of cell cell adhesion GO:0022407 21 0.011
epithelial cell differentiation GO:0030855 322 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of cell adhesion GO:0030155 27 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
compound eye morphogenesis GO:0001745 249 0.011
establishment of planar polarity GO:0001736 87 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
respiratory system development GO:0060541 213 0.010
chemical homeostasis GO:0048878 92 0.010
jak stat cascade GO:0007259 49 0.010
glucosamine containing compound metabolic process GO:1901071 9 0.010
divalent inorganic cation homeostasis GO:0072507 29 0.010
tissue morphogenesis GO:0048729 297 0.010
positive regulation of antifungal peptide production GO:0002804 6 0.010
actin filament organization GO:0007015 126 0.010
regulation of antifungal peptide production GO:0002788 6 0.010
macromolecular complex assembly GO:0065003 256 0.010
open tracheal system development GO:0007424 204 0.010
establishment of protein localization GO:0045184 163 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
neuronal action potential GO:0019228 10 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
camera type eye development GO:0043010 4 0.010
response to abiotic stimulus GO:0009628 341 0.010
protein complex biogenesis GO:0070271 201 0.010

PGRP-SA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012