Drosophila melanogaster

36 known processes

Sara (Dmel_CG15667)

Smad anchor for receptor activation

(Aliases: CG15667,Dmel\CG15667,SARA,sara,dSARA)

Sara biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.902
regulation of synapse structure and activity GO:0050803 128 0.881
axon development GO:0061564 297 0.855
imaginal disc derived appendage morphogenesis GO:0035114 395 0.770
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.763
intracellular signal transduction GO:0035556 300 0.755
axonogenesis GO:0007409 290 0.749
cell division GO:0051301 248 0.748
protein modification process GO:0036211 438 0.662
establishment of localization in cell GO:0051649 402 0.637
Human
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.586
imaginal disc derived wing morphogenesis GO:0007476 337 0.582
appendage morphogenesis GO:0035107 397 0.540
positive regulation of protein metabolic process GO:0051247 128 0.498
bmp signaling pathway GO:0030509 27 0.469
imaginal disc derived appendage development GO:0048737 399 0.462
eye development GO:0001654 323 0.449
post embryonic appendage morphogenesis GO:0035120 385 0.438
apoptotic process GO:0006915 159 0.436
chromosome organization GO:0051276 360 0.427
embryo development ending in birth or egg hatching GO:0009792 152 0.424
positive regulation of protein kinase activity GO:0045860 25 0.399
regulation of protein kinase activity GO:0045859 51 0.398
regulation of protein modification process GO:0031399 112 0.397
sensory organ morphogenesis GO:0090596 260 0.392
regionalization GO:0003002 416 0.374
positive regulation of response to stimulus GO:0048584 323 0.373
protein phosphorylation GO:0006468 169 0.368
compound eye development GO:0048749 307 0.367
cellular protein catabolic process GO:0044257 83 0.363
regulation of cellular amino acid metabolic process GO:0006521 0 0.359
regulation of phosphate metabolic process GO:0019220 210 0.349
negative regulation of signal transduction GO:0009968 206 0.349
ubiquitin dependent protein catabolic process GO:0006511 78 0.346
regulation of mitotic cell cycle GO:0007346 190 0.330
regulation of cell cycle process GO:0010564 181 0.328
cell motility GO:0048870 251 0.327
appendage development GO:0048736 401 0.322
regulation of protein metabolic process GO:0051246 256 0.320
regulation of molecular function GO:0065009 217 0.311
wing disc morphogenesis GO:0007472 344 0.303
synapse organization GO:0050808 196 0.286
positive regulation of cellular component organization GO:0051130 156 0.286
single organism intracellular transport GO:1902582 207 0.285
Human
signal transduction by phosphorylation GO:0023014 107 0.284
positive regulation of cellular protein metabolic process GO:0032270 118 0.281
positive regulation of transcription dna templated GO:0045893 266 0.279
regulation of synapse assembly GO:0051963 94 0.272
regulation of cellular protein metabolic process GO:0032268 243 0.272
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.270
modification dependent macromolecule catabolic process GO:0043632 79 0.268
protein ubiquitination GO:0016567 70 0.262
positive regulation of cellular amine metabolic process GO:0033240 0 0.255
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.254
ameboidal type cell migration GO:0001667 151 0.250
cellular macromolecule catabolic process GO:0044265 136 0.249
regulation of cell proliferation GO:0042127 163 0.238
proteolysis GO:0006508 192 0.238
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.235
synapse assembly GO:0007416 143 0.233
endocytosis GO:0006897 310 0.233
regulation of bmp signaling pathway GO:0030510 23 0.227
peptidyl threonine phosphorylation GO:0018107 2 0.226
transmembrane transport GO:0055085 139 0.223
homeostatic process GO:0042592 199 0.221
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.220
protein modification by small protein conjugation GO:0032446 79 0.219
regulation of nervous system development GO:0051960 248 0.219
positive regulation of nucleic acid templated transcription GO:1903508 266 0.217
regulation of ion transport GO:0043269 39 0.216
positive regulation of phosphorus metabolic process GO:0010562 139 0.215
cell death GO:0008219 279 0.213
cell migration GO:0016477 238 0.211
regulation of endocytosis GO:0030100 37 0.210
positive regulation of gene expression GO:0010628 290 0.203
regulation of cellular catabolic process GO:0031329 157 0.200
regulation of catalytic activity GO:0050790 185 0.199
dorsal ventral pattern formation GO:0009953 133 0.198
regulation of cell cycle GO:0051726 291 0.191
amine metabolic process GO:0009308 12 0.191
regulation of vesicle mediated transport GO:0060627 59 0.190
regulation of cellular ketone metabolic process GO:0010565 3 0.189
endomembrane system organization GO:0010256 119 0.189
regulation of localization GO:0032879 275 0.186
regulation of cellular amine metabolic process GO:0033238 3 0.184
regulation of phosphorus metabolic process GO:0051174 210 0.183
macromolecule catabolic process GO:0009057 161 0.183
cell proliferation GO:0008283 299 0.181
phosphorylation GO:0016310 294 0.181
positive regulation of protein modification process GO:0031401 58 0.181
positive regulation of developmental process GO:0051094 143 0.180
positive regulation of rna biosynthetic process GO:1902680 266 0.177
ion transmembrane transport GO:0034220 122 0.173
regulation of neurogenesis GO:0050767 158 0.169
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.168
proteasomal protein catabolic process GO:0010498 59 0.165
anatomical structure homeostasis GO:0060249 97 0.162
positive regulation of phosphate metabolic process GO:0045937 139 0.160
cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090255 2 0.158
regulation of synapse organization GO:0050807 110 0.158
eye morphogenesis GO:0048592 260 0.157
compound eye morphogenesis GO:0001745 249 0.155
regulation of multicellular organismal development GO:2000026 414 0.153
cellular ketone metabolic process GO:0042180 24 0.150
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.150
Human
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.149
Human
positive regulation of synapse assembly GO:0051965 29 0.148
positive regulation of rna metabolic process GO:0051254 271 0.148
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.145
regulation of mitotic cell cycle phase transition GO:1901990 130 0.144
positive regulation of cellular component biogenesis GO:0044089 80 0.141
glycoprotein biosynthetic process GO:0009101 41 0.141
negative regulation of cell cycle GO:0045786 116 0.140
cellular amine metabolic process GO:0044106 12 0.137
regulation of transmembrane transport GO:0034762 27 0.133
positive regulation of molecular function GO:0044093 136 0.132
intracellular transport GO:0046907 228 0.131
Human
chromatin modification GO:0016568 147 0.127
positive regulation of multicellular organismal process GO:0051240 143 0.124
activation of protein kinase activity GO:0032147 12 0.124
negative regulation of phosphorus metabolic process GO:0010563 45 0.124
axon guidance GO:0007411 233 0.124
cell growth GO:0016049 108 0.123
positive regulation of biosynthetic process GO:0009891 316 0.122
regulation of protein serine threonine kinase activity GO:0071900 25 0.119
positive regulation of transport GO:0051050 92 0.119
ion transport GO:0006811 145 0.118
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.117
mapk cascade GO:0000165 107 0.115
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.115
positive regulation of signal transduction GO:0009967 223 0.115
regulation of protein localization GO:0032880 76 0.114
neuromuscular junction development GO:0007528 149 0.113
regulation of intracellular signal transduction GO:1902531 236 0.113
organonitrogen compound metabolic process GO:1901564 318 0.112
stem cell division GO:0017145 69 0.111
aging GO:0007568 143 0.110
Worm
vesicle mediated transport GO:0016192 381 0.109
autophagy GO:0006914 108 0.108
neuron projection guidance GO:0097485 241 0.108
regulation of growth GO:0040008 233 0.105
regulation of mapk cascade GO:0043408 92 0.105
protein catabolic process GO:0030163 101 0.105
imaginal disc derived wing vein specification GO:0007474 48 0.105
localization of cell GO:0051674 257 0.104
catabolic process GO:0009056 409 0.101
regulation of cell cycle phase transition GO:1901987 130 0.100
organelle fission GO:0048285 340 0.099
negative regulation of phosphorylation GO:0042326 35 0.098
negative regulation of protein modification process GO:0031400 29 0.098
telomere organization GO:0032200 21 0.097
ras protein signal transduction GO:0007265 88 0.096
negative regulation of signaling GO:0023057 219 0.094
negative regulation of cell proliferation GO:0008285 69 0.092
organic substance transport GO:0071702 257 0.091
Human
programmed cell death GO:0012501 257 0.089
protein processing GO:0016485 68 0.088
response to growth factor GO:0070848 31 0.088
Human
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.087
imaginal disc pattern formation GO:0007447 91 0.087
single organismal cell cell adhesion GO:0016337 45 0.086
regulation of kinase activity GO:0043549 53 0.086
tube development GO:0035295 244 0.086
negative regulation of cellular protein metabolic process GO:0032269 85 0.085
photoreceptor cell differentiation GO:0046530 170 0.084
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.083
regulation of hydrolase activity GO:0051336 97 0.083
kidney development GO:0001822 3 0.083
enzyme linked receptor protein signaling pathway GO:0007167 179 0.082
Human
positive regulation of protein phosphorylation GO:0001934 34 0.082
positive regulation of phosphorylation GO:0042327 87 0.081
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.080
transcription from rna polymerase ii promoter GO:0006366 368 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.079
regulation of developmental growth GO:0048638 174 0.079
cellular protein modification process GO:0006464 438 0.078
sterol homeostasis GO:0055092 4 0.078
peptidyl amino acid modification GO:0018193 105 0.078
positive regulation of catalytic activity GO:0043085 118 0.077
regulation of cellular response to growth factor stimulus GO:0090287 13 0.077
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.077
neuron death GO:0070997 27 0.076
stem cell proliferation GO:0072089 88 0.075
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.075
cell rearrangement involved in malpighian tubule morphogenesis GO:0061334 3 0.075
synaptic growth at neuromuscular junction GO:0051124 119 0.074
monocarboxylic acid transport GO:0015718 3 0.074
regulation of cellular response to stress GO:0080135 89 0.072
endodermal cell fate commitment GO:0001711 3 0.072
single organism cellular localization GO:1902580 180 0.072
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.072
negative regulation of response to stimulus GO:0048585 258 0.072
negative regulation of epithelial cell proliferation GO:0050680 4 0.071
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.071
mitotic nuclear division GO:0007067 213 0.070
protein localization to plasma membrane GO:0072659 13 0.068
positive regulation of transferase activity GO:0051347 26 0.068
negative regulation of phosphate metabolic process GO:0045936 45 0.066
regulation of phosphorylation GO:0042325 147 0.066
regulation of receptor mediated endocytosis GO:0048259 9 0.065
cellular amino acid metabolic process GO:0006520 61 0.065
negative regulation of developmental growth GO:0048640 64 0.064
growth GO:0040007 359 0.064
epithelial cell migration GO:0010631 148 0.064
protein targeting to nucleus GO:0044744 51 0.063
Human
response to organic substance GO:0010033 284 0.062
Human
mitotic cytokinesis GO:0000281 50 0.062
negative regulation of cell communication GO:0010648 223 0.062
cell cycle phase transition GO:0044770 140 0.061
developmental growth GO:0048589 280 0.060
regulation of erbb signaling pathway GO:1901184 42 0.060
protein complex biogenesis GO:0070271 201 0.060
Human
negative regulation of mapk cascade GO:0043409 23 0.060
embryonic development via the syncytial blastoderm GO:0001700 148 0.059
single organism membrane organization GO:0044802 93 0.059
regulation of anatomical structure morphogenesis GO:0022603 242 0.059
regulation of transport GO:0051049 181 0.059
regulation of cell development GO:0060284 215 0.058
positive regulation of signaling GO:0023056 243 0.058
cellular response to nutrient levels GO:0031669 62 0.057
regulation of cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090256 2 0.057
peptidyl threonine modification GO:0018210 3 0.056
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.056
positive regulation of cellular biosynthetic process GO:0031328 316 0.055
regulation of ras protein signal transduction GO:0046578 93 0.055
regulation of protein phosphorylation GO:0001932 64 0.054
mitotic cell cycle phase transition GO:0044772 138 0.053
eye antennal disc development GO:0035214 60 0.053
cellular response to chemical stimulus GO:0070887 199 0.053
Human
anion transport GO:0006820 41 0.053
nuclear division GO:0000280 332 0.053
camera type eye development GO:0043010 4 0.053
kidney epithelium development GO:0072073 3 0.053
neural precursor cell proliferation GO:0061351 75 0.052
positive regulation of protein transport GO:0051222 37 0.052
connective tissue development GO:0061448 3 0.052
cellular lipid metabolic process GO:0044255 83 0.052
oxoacid metabolic process GO:0043436 103 0.051
negative regulation of catalytic activity GO:0043086 42 0.051
regulation of protein tyrosine kinase activity GO:0061097 9 0.051
epithelium migration GO:0090132 148 0.051
regulation of immune system process GO:0002682 176 0.050
cell cycle checkpoint GO:0000075 95 0.050
tube morphogenesis GO:0035239 191 0.050
activation of mapk activity GO:0000187 9 0.050
cytokinesis GO:0000910 90 0.050
lateral inhibition GO:0046331 206 0.049
cytoskeleton dependent cytokinesis GO:0061640 81 0.049
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.049
chromatin organization GO:0006325 207 0.049
establishment of protein localization GO:0045184 163 0.049
Human
single organism nuclear import GO:1902593 51 0.049
Human
negative regulation of molecular function GO:0044092 51 0.048
regulation of epithelial cell proliferation GO:0050678 4 0.048
single organism membrane fusion GO:0044801 42 0.048
peptidyl tyrosine modification GO:0018212 24 0.047
macromolecular complex assembly GO:0065003 256 0.047
Human
positive regulation of cellular catabolic process GO:0031331 95 0.046
regulation of cellular component biogenesis GO:0044087 201 0.046
multicellular organismal aging GO:0010259 140 0.045
Worm
carbohydrate biosynthetic process GO:0016051 17 0.045
establishment of organelle localization GO:0051656 122 0.044
regulation of cell adhesion GO:0030155 27 0.044
positive regulation of kinase activity GO:0033674 25 0.044
body morphogenesis GO:0010171 2 0.043
organic substance catabolic process GO:1901575 308 0.043
regulation of map kinase activity GO:0043405 17 0.043
small gtpase mediated signal transduction GO:0007264 88 0.042
negative regulation of growth GO:0045926 84 0.042
regulation of cellular component size GO:0032535 98 0.042
positive regulation of intracellular signal transduction GO:1902533 116 0.041
modification dependent protein catabolic process GO:0019941 78 0.041
regulation of cell division GO:0051302 72 0.041
positive regulation of developmental growth GO:0048639 62 0.041
cell cell signaling involved in cell fate commitment GO:0045168 210 0.040
jnk cascade GO:0007254 50 0.040
regulation of apoptotic process GO:0042981 130 0.040
cortical cytoskeleton organization GO:0030865 29 0.040
mitotic dna damage checkpoint GO:0044773 74 0.040
negative regulation of autophagy GO:0010507 16 0.039
carboxylic acid metabolic process GO:0019752 92 0.039
unidimensional cell growth GO:0009826 15 0.039
negative regulation of developmental process GO:0051093 201 0.039
cellular response to starvation GO:0009267 61 0.039
death GO:0016265 284 0.039
regulation of cell size GO:0008361 63 0.038
lipid metabolic process GO:0006629 121 0.038
wing disc pattern formation GO:0035222 66 0.037
hindgut development GO:0061525 58 0.037
protein maturation GO:0051604 71 0.037
central nervous system development GO:0007417 201 0.037
mitochondrion organization GO:0007005 65 0.037
protein autophosphorylation GO:0046777 15 0.037
regulation of programmed cell death GO:0043067 152 0.037
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.037
regulation of catabolic process GO:0009894 170 0.037
telomere maintenance GO:0000723 21 0.037
response to radiation GO:0009314 155 0.036
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.036
imaginal disc derived leg morphogenesis GO:0007480 80 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.035
spindle assembly GO:0051225 80 0.035
negative regulation of protein metabolic process GO:0051248 85 0.035
protein import into nucleus GO:0006606 51 0.035
Human
cellular catabolic process GO:0044248 372 0.034
pathway restricted smad protein phosphorylation GO:0060389 1 0.034
regulation of transferase activity GO:0051338 58 0.034
cortical actin cytoskeleton organization GO:0030866 24 0.034
organic acid metabolic process GO:0006082 103 0.034
compound eye photoreceptor cell differentiation GO:0001751 140 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
morphogenesis of larval imaginal disc epithelium GO:0016335 5 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.034
positive regulation of mapk cascade GO:0043410 63 0.033
histone modification GO:0016570 106 0.033
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.033
regulation of dna metabolic process GO:0051052 34 0.033
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.033
negative regulation of cell cycle process GO:0010948 109 0.033
stem cell differentiation GO:0048863 117 0.032
axon cargo transport GO:0008088 29 0.032
respiratory system development GO:0060541 213 0.032
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.032
spindle organization GO:0007051 253 0.032
defense response to virus GO:0051607 23 0.032
regulation of autophagy GO:0010506 62 0.031
regulation of cytoplasmic transport GO:1903649 47 0.031
protein complex assembly GO:0006461 200 0.030
Human
covalent chromatin modification GO:0016569 106 0.030
neuroblast proliferation GO:0007405 74 0.030
muscle cell differentiation GO:0042692 103 0.030
morphogenesis of a branching epithelium GO:0061138 45 0.030
regulation of transmembrane transporter activity GO:0022898 6 0.030
regulation of organelle organization GO:0033043 196 0.029
positive regulation of catabolic process GO:0009896 105 0.029
carboxylic acid transport GO:0046942 18 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.029
immune system process GO:0002376 347 0.028
positive regulation of protein catabolic process GO:0045732 34 0.028
negative regulation of apoptotic process GO:0043066 63 0.028
positive regulation of cell communication GO:0010647 250 0.028
negative regulation of programmed cell death GO:0043069 72 0.027
positive regulation of protein localization to nucleus GO:1900182 21 0.027
regulation of small gtpase mediated signal transduction GO:0051056 93 0.027
negative regulation of cellular response to growth factor stimulus GO:0090288 6 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.027
gastrulation GO:0007369 70 0.026
negative regulation of mitotic cell cycle GO:0045930 109 0.026
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.026
negative regulation of notch signaling pathway GO:0045746 41 0.026
anterior posterior pattern specification imaginal disc GO:0007448 16 0.026
positive regulation of gtpase activity GO:0043547 43 0.026
extracellular structure organization GO:0043062 46 0.026
phosphatidylinositol mediated signaling GO:0048015 4 0.026
negative regulation of epithelial cell migration GO:0010633 1 0.025
developmental growth involved in morphogenesis GO:0060560 65 0.025
germ line stem cell maintenance GO:0030718 50 0.025
positive regulation of nervous system development GO:0051962 69 0.025
regulation of proteolysis GO:0030162 87 0.025
stress activated mapk cascade GO:0051403 52 0.025
endodermal cell differentiation GO:0035987 3 0.025
positive regulation of proteolysis GO:0045862 52 0.025
embryonic morphogenesis GO:0048598 206 0.025
organic acid transport GO:0015849 18 0.025
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.024
regulation of intracellular protein transport GO:0033157 46 0.024
endoderm formation GO:0001706 3 0.024
phagocytosis GO:0006909 215 0.024
mitotic spindle organization GO:0007052 220 0.024
regulation of mitosis GO:0007088 56 0.024
organelle fusion GO:0048284 46 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.023
positive regulation of growth GO:0045927 75 0.023
positive regulation of endocytosis GO:0045807 22 0.023
negative regulation of protein phosphorylation GO:0001933 17 0.023
regulation of defense response to virus by host GO:0050691 10 0.023
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.023
organic anion transport GO:0015711 28 0.023
actin filament based process GO:0030029 220 0.023
negative regulation of cell division GO:0051782 17 0.023
response to light stimulus GO:0009416 124 0.023
signal transduction in response to dna damage GO:0042770 3 0.023
border follicle cell migration GO:0007298 113 0.023
glycerolipid metabolic process GO:0046486 34 0.023
necrotic cell death GO:0070265 1 0.023
open tracheal system development GO:0007424 204 0.023
negative regulation of multicellular organismal process GO:0051241 142 0.023
small molecule metabolic process GO:0044281 305 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.022
positive regulation of organelle organization GO:0010638 65 0.022
dna damage checkpoint GO:0000077 78 0.022
negative regulation of kinase activity GO:0033673 16 0.022
muscle structure development GO:0061061 224 0.021
axis specification GO:0009798 167 0.021
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.021
muscle cell development GO:0055001 50 0.021
regulation of cell death GO:0010941 173 0.021
protein localization GO:0008104 284 0.020
Human
stress activated protein kinase signaling cascade GO:0031098 55 0.020
organelle localization GO:0051640 148 0.020
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.020
microtubule based movement GO:0007018 51 0.020
peptidyl tyrosine phosphorylation GO:0018108 24 0.020
actomyosin structure organization GO:0031032 56 0.020
regulation of intracellular transport GO:0032386 64 0.020
regulation of protein catabolic process GO:0042176 55 0.020
compound eye photoreceptor development GO:0042051 78 0.020
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.020
positive regulation of cell cycle g2 m phase transition GO:1902751 2 0.020
epithelial cell differentiation GO:0030855 322 0.019
nucleoside catabolic process GO:0009164 112 0.019
regulation of rab protein signal transduction GO:0032483 7 0.019
positive regulation of cell development GO:0010720 61 0.019
photoreceptor cell development GO:0042461 96 0.019
axon extension GO:0048675 32 0.019
kidney morphogenesis GO:0060993 3 0.018
taxis GO:0042330 304 0.018
positive regulation of ras gtpase activity GO:0032320 36 0.018
regulation of erk1 and erk2 cascade GO:0070372 39 0.018
activation of cysteine type endopeptidase activity GO:0097202 17 0.018
positive regulation of phagocytosis engulfment GO:0060100 1 0.018
regulation of chromosome organization GO:0033044 64 0.018
determination of dorsal ventral asymmetry GO:0048262 3 0.018
cellular macromolecule localization GO:0070727 220 0.018
Human
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
developmental pigmentation GO:0048066 68 0.018
digestive tract morphogenesis GO:0048546 127 0.018
nephron tubule development GO:0072080 3 0.018
eye photoreceptor cell development GO:0042462 81 0.018
response to virus GO:0009615 28 0.018
cellular protein localization GO:0034613 160 0.017
Human
regulation of metal ion transport GO:0010959 15 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
regulation of organ formation GO:0003156 3 0.017
chemical homeostasis GO:0048878 92 0.017
regulation of neuron differentiation GO:0045664 103 0.017
apoptotic signaling pathway GO:0097190 27 0.017
metal ion transport GO:0030001 74 0.017
chromosome separation GO:0051304 42 0.017
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.017
epidermal growth factor receptor signaling pathway GO:0007173 58 0.017
sister chromatid segregation GO:0000819 92 0.017
segmentation GO:0035282 207 0.017
response to abiotic stimulus GO:0009628 341 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
positive regulation of peptidase activity GO:0010952 29 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
multicellular organism growth GO:0035264 46 0.016
regulation of jnk cascade GO:0046328 40 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
circulatory system development GO:0072359 82 0.016
regulation of neuron projection development GO:0010975 69 0.016
synaptic transmission GO:0007268 288 0.016
regulation of cellular localization GO:0060341 136 0.016
germ band extension GO:0007377 11 0.016
pigmentation GO:0043473 75 0.016
morphogenesis of a branching structure GO:0001763 45 0.016
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.016
mushroom body development GO:0016319 70 0.016
sulfur compound metabolic process GO:0006790 59 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
response to axon injury GO:0048678 12 0.016
regulation of protein import into nucleus GO:0042306 28 0.016
developmental cell growth GO:0048588 52 0.016
cytoskeleton dependent intracellular transport GO:0030705 44 0.016
negative regulation of transferase activity GO:0051348 18 0.016
digestive system development GO:0055123 149 0.015
male meiosis cytokinesis GO:0007112 26 0.015
somatic muscle development GO:0007525 66 0.015
protein localization to nucleus GO:0034504 55 0.015
Human
nucleocytoplasmic transport GO:0006913 72 0.015
Human
vesicle organization GO:0016050 44 0.015
embryonic hindgut morphogenesis GO:0048619 48 0.015
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.015
wing disc anterior posterior pattern formation GO:0048100 5 0.015
protein import GO:0017038 55 0.015
Human
regulation of cell growth GO:0001558 43 0.015
regulation of nucleocytoplasmic transport GO:0046822 35 0.015
membrane organization GO:0061024 112 0.015
chemotaxis GO:0006935 249 0.015
integrin mediated signaling pathway GO:0007229 3 0.015
negative regulation of cell death GO:0060548 81 0.015
cellular response to external stimulus GO:0071496 66 0.015
positive regulation of response to external stimulus GO:0032103 44 0.015
germ line stem cell division GO:0042078 25 0.015
regulation of response to oxidative stress GO:1902882 4 0.015
dendrite development GO:0016358 204 0.015

Sara disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.124
disease of cellular proliferation DOID:14566 0 0.124
organ system cancer DOID:0050686 0 0.124
motor neuron disease DOID:231 0 0.025
central nervous system disease DOID:331 0 0.025
disease of anatomical entity DOID:7 0 0.025
neurodegenerative disease DOID:1289 0 0.025
nervous system disease DOID:863 0 0.025