Drosophila melanogaster

0 known processes

Ret (Dmel_CG14396)

Ret oncogene

(Aliases: HD-59,DmHD-59,CG1061,dRET,dRet,Reto,DRET,MEN2,DRet,D-ret,RET,CG14396,Dmel\CG14396,Dret,ret)

Ret biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 237 0.211
tube development GO:0035295 244 0.199
Fly
cell motility GO:0048870 251 0.143
Fly
sensory perception GO:0007600 196 0.136
negative regulation of rna biosynthetic process GO:1902679 240 0.123
positive regulation of macromolecule metabolic process GO:0010604 405 0.122
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.118
localization of cell GO:0051674 257 0.116
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.113
negative regulation of rna metabolic process GO:0051253 251 0.110
negative regulation of gene expression GO:0010629 387 0.103
digestive system development GO:0055123 149 0.095
Fly
positive regulation of biosynthetic process GO:0009891 316 0.095
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.090
wing disc morphogenesis GO:0007472 344 0.086
negative regulation of biosynthetic process GO:0009890 277 0.086
morphogenesis of an epithelium GO:0002009 276 0.084
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.082
cell migration GO:0016477 238 0.082
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.081
positive regulation of transcription dna templated GO:0045893 266 0.080
sensory perception of chemical stimulus GO:0007606 116 0.074
imaginal disc derived appendage morphogenesis GO:0035114 395 0.070
post embryonic appendage morphogenesis GO:0035120 385 0.070
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
digestive tract development GO:0048565 149 0.067
Fly
tissue morphogenesis GO:0048729 297 0.066
Fly
neurological system process GO:0050877 358 0.066
appendage morphogenesis GO:0035107 397 0.064
positive regulation of rna metabolic process GO:0051254 271 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.063
transcription from rna polymerase ii promoter GO:0006366 368 0.062
taxis GO:0042330 304 0.061
chaeta development GO:0022416 97 0.061
appendage development GO:0048736 401 0.059
respiratory system development GO:0060541 213 0.059
Fly
response to extracellular stimulus GO:0009991 116 0.059
response to nutrient levels GO:0031667 114 0.058
cell cell signaling involved in cell fate commitment GO:0045168 210 0.057
response to starvation GO:0042594 97 0.057
positive regulation of rna biosynthetic process GO:1902680 266 0.057
small molecule metabolic process GO:0044281 305 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.054
tube morphogenesis GO:0035239 191 0.054
Fly
cellular response to extracellular stimulus GO:0031668 64 0.054
inter male aggressive behavior GO:0002121 60 0.053
aromatic compound catabolic process GO:0019439 166 0.050
positive regulation of nucleic acid templated transcription GO:1903508 266 0.049
single organism behavior GO:0044708 391 0.049
intracellular signal transduction GO:0035556 300 0.049
Fly
response to organic substance GO:0010033 284 0.049
organonitrogen compound metabolic process GO:1901564 318 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.048
catabolic process GO:0009056 409 0.046
eye antennal disc development GO:0035214 60 0.044
embryonic morphogenesis GO:0048598 206 0.044
Fly
organic substance catabolic process GO:1901575 308 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.043
cell proliferation GO:0008283 299 0.043
chemosensory behavior GO:0007635 106 0.043
heterocycle catabolic process GO:0046700 166 0.043
cellular response to external stimulus GO:0071496 66 0.042
response to other organism GO:0051707 293 0.042
Fly
response to oxygen containing compound GO:1901700 200 0.042
aggressive behavior GO:0002118 63 0.041
regionalization GO:0003002 416 0.041
imaginal disc derived appendage development GO:0048737 399 0.041
axonogenesis GO:0007409 290 0.040
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
epithelial tube morphogenesis GO:0060562 88 0.040
Fly
response to external biotic stimulus GO:0043207 293 0.040
Fly
cellular catabolic process GO:0044248 372 0.040
cellular response to chemical stimulus GO:0070887 199 0.039
open tracheal system development GO:0007424 204 0.038
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
positive regulation of response to stimulus GO:0048584 323 0.037
Fly
regulation of phosphate metabolic process GO:0019220 210 0.037
Fly
epithelial cell development GO:0002064 274 0.036
Fly
dendrite morphogenesis GO:0048813 199 0.036
enzyme linked receptor protein signaling pathway GO:0007167 179 0.036
response to alcohol GO:0097305 95 0.035
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
eye development GO:0001654 323 0.034
gland development GO:0048732 191 0.033
Fly
positive regulation of gene expression GO:0010628 290 0.032
cell death GO:0008219 279 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.032
macromolecular complex assembly GO:0065003 256 0.032
single organism catabolic process GO:0044712 228 0.032
lateral inhibition GO:0046331 206 0.031
regulation of molecular function GO:0065009 217 0.031
Fly
regulation of intracellular signal transduction GO:1902531 236 0.030
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
regulation of cell differentiation GO:0045595 302 0.028
Fly
blastoderm segmentation GO:0007350 159 0.028
detection of stimulus involved in sensory perception GO:0050906 92 0.027
organic acid metabolic process GO:0006082 103 0.027
organelle fission GO:0048285 340 0.027
negative regulation of multicellular organismal process GO:0051241 142 0.027
Fly
regulation of localization GO:0032879 275 0.027
axon development GO:0061564 297 0.027
Fly
response to lipopolysaccharide GO:0032496 4 0.026
protein heterooligomerization GO:0051291 4 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
Fly
response to bacterium GO:0009617 198 0.026
Fly
axon guidance GO:0007411 233 0.026
death GO:0016265 284 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
negative regulation of cell communication GO:0010648 223 0.026
negative regulation of signaling GO:0023057 219 0.026
negative regulation of signal transduction GO:0009968 206 0.026
organophosphate metabolic process GO:0019637 195 0.026
segmentation GO:0035282 207 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
organelle localization GO:0051640 148 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.025
regulation of cell cycle GO:0051726 291 0.025
establishment or maintenance of cell polarity GO:0007163 167 0.025
positive regulation of catalytic activity GO:0043085 118 0.025
Fly
cell projection assembly GO:0030031 94 0.025
Fly
purine containing compound metabolic process GO:0072521 155 0.025
positive regulation of signaling GO:0023056 243 0.024
Fly
response to biotic stimulus GO:0009607 294 0.024
Fly
kidney development GO:0001822 3 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
ribonucleotide metabolic process GO:0009259 145 0.024
neuron projection guidance GO:0097485 241 0.024
programmed cell death GO:0012501 257 0.024
detection of stimulus GO:0051606 156 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
positive regulation of signal transduction GO:0009967 223 0.023
Fly
regulation of catalytic activity GO:0050790 185 0.023
Fly
carboxylic acid metabolic process GO:0019752 92 0.023
phosphorylation GO:0016310 294 0.023
Fly
regulation of cell death GO:0010941 173 0.023
synaptic transmission GO:0007268 288 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
growth GO:0040007 359 0.022
Fly
vesicle mediated transport GO:0016192 381 0.022
hindgut development GO:0061525 58 0.022
chemotaxis GO:0006935 249 0.022
regulation of anatomical structure size GO:0090066 163 0.022
Fly
apoptotic process GO:0006915 159 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
germ cell migration GO:0008354 43 0.022
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.022
Fly
cell adhesion GO:0007155 136 0.022
dendrite development GO:0016358 204 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
regulation of cell development GO:0060284 215 0.022
Fly
regulation of programmed cell death GO:0043067 152 0.021
protein localization GO:0008104 284 0.021
establishment of localization in cell GO:0051649 402 0.021
camera type eye development GO:0043010 4 0.021
detection of chemical stimulus GO:0009593 93 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
neuron recognition GO:0008038 101 0.021
phosphate ion transport GO:0006817 4 0.021
compound eye development GO:0048749 307 0.021
compound eye morphogenesis GO:0001745 249 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.020
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
salivary gland development GO:0007431 162 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
developmental maturation GO:0021700 172 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
regulation of organelle organization GO:0033043 196 0.020
gtp catabolic process GO:0006184 72 0.020
olfactory behavior GO:0042048 97 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
nuclear division GO:0000280 332 0.020
cellular response to nutrient levels GO:0031669 62 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
cellular macromolecular complex assembly GO:0034622 153 0.019
regulation of catabolic process GO:0009894 170 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
positive regulation of cell communication GO:0010647 250 0.019
Fly
purine ribonucleotide catabolic process GO:0009154 109 0.019
nucleotide metabolic process GO:0009117 161 0.019
epithelial cell differentiation GO:0030855 322 0.019
Fly
positive regulation of gtp catabolic process GO:0033126 43 0.019
defense response to bacterium GO:0042742 178 0.019
Fly
protein complex assembly GO:0006461 200 0.019
regulation of nervous system development GO:0051960 248 0.019
Fly
intracellular transport GO:0046907 228 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.018
regulation of response to stress GO:0080134 200 0.018
Fly
spindle organization GO:0007051 253 0.018
actin filament organization GO:0007015 126 0.018
developmental growth involved in morphogenesis GO:0060560 65 0.018
Fly
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.018
positive regulation of cell migration GO:0030335 2 0.018
photoreceptor cell differentiation GO:0046530 170 0.018
regulation of cell proliferation GO:0042127 163 0.018
phagocytosis GO:0006909 215 0.018
biological adhesion GO:0022610 138 0.017
steroid catabolic process GO:0006706 1 0.017
response to abiotic stimulus GO:0009628 341 0.017
response to organophosphorus GO:0046683 2 0.017
muscle structure development GO:0061061 224 0.017
Fly
regulation of immune system process GO:0002682 176 0.017
Fly
regulation of mitotic cell cycle GO:0007346 190 0.017
negative regulation of developmental process GO:0051093 201 0.017
Fly
single organism biosynthetic process GO:0044711 206 0.017
exocrine system development GO:0035272 162 0.017
skin development GO:0043588 65 0.017
maintenance of location GO:0051235 73 0.017
nucleoside metabolic process GO:0009116 127 0.016
cell division GO:0051301 248 0.016
notch signaling pathway GO:0007219 120 0.016
regulation of cellular localization GO:0060341 136 0.016
cilium morphogenesis GO:0060271 39 0.016
developmental growth GO:0048589 280 0.016
Fly
defense response GO:0006952 300 0.016
Fly
central nervous system development GO:0007417 201 0.016
Fly
protein phosphorylation GO:0006468 169 0.016
Fly
response to nitrogen compound GO:1901698 90 0.016
nucleotide catabolic process GO:0009166 109 0.016
amine metabolic process GO:0009308 12 0.016
regulation of protein metabolic process GO:0051246 256 0.016
Fly
regulation of gtp catabolic process GO:0033124 44 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
establishment of organelle localization GO:0051656 122 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
organic substance transport GO:0071702 257 0.016
axis specification GO:0009798 167 0.016
protein modification process GO:0036211 438 0.016
Fly
hindgut morphogenesis GO:0007442 58 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
Fly
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.015
digestive tract morphogenesis GO:0048546 127 0.015
Fly
tissue migration GO:0090130 155 0.015
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.015
ras protein signal transduction GO:0007265 88 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
eye antennal disc morphogenesis GO:0007455 34 0.015
immune system process GO:0002376 347 0.015
Fly
ameboidal type cell migration GO:0001667 151 0.015
Fly
gland morphogenesis GO:0022612 145 0.015
cellular macromolecule localization GO:0070727 220 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
mitotic nuclear division GO:0007067 213 0.015
defense response to other organism GO:0098542 225 0.015
Fly
ribonucleotide catabolic process GO:0009261 109 0.015
establishment of protein localization GO:0045184 163 0.015
oocyte differentiation GO:0009994 145 0.015
cell maturation GO:0048469 144 0.015
endocytosis GO:0006897 310 0.015
body morphogenesis GO:0010171 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
negative regulation of cell death GO:0060548 81 0.015
nephron development GO:0072006 3 0.015
nucleoside catabolic process GO:0009164 112 0.015
single organism intracellular transport GO:1902582 207 0.015
ovarian follicle cell development GO:0030707 248 0.015
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.015
Fly
regulation of hydrolase activity GO:0051336 97 0.014
protein transport GO:0015031 155 0.014
regulation of apoptotic process GO:0042981 130 0.014
sensory perception of salty taste GO:0050914 3 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
chromosome segregation GO:0007059 157 0.014
chromatin organization GO:0006325 207 0.014
actin cytoskeleton organization GO:0030036 206 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
cell recognition GO:0008037 102 0.014
cellular amine metabolic process GO:0044106 12 0.014
dna metabolic process GO:0006259 227 0.014
epithelial cell migration GO:0010631 148 0.014
Fly
negative regulation of mitotic cell cycle GO:0045930 109 0.014
organophosphate catabolic process GO:0046434 112 0.014
peptidyl amino acid modification GO:0018193 105 0.014
Fly
stem cell differentiation GO:0048863 117 0.014
Fly
cell fate determination GO:0001709 91 0.014
Fly
male mating behavior GO:0060179 70 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
positive regulation of catabolic process GO:0009896 105 0.014
response to ethanol GO:0045471 59 0.014
positive regulation of cell death GO:0010942 69 0.014
regulation of transport GO:0051049 181 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
Fly
regulation of developmental growth GO:0048638 174 0.014
Fly
regulation of notch signaling pathway GO:0008593 100 0.014
gastrulation GO:0007369 70 0.014
Fly
regulation of cell cycle process GO:0010564 181 0.014
renal tubule development GO:0061326 64 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
salivary gland morphogenesis GO:0007435 145 0.014
connective tissue development GO:0061448 3 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
Fly
positive regulation of phosphate metabolic process GO:0045937 139 0.013
Fly
cognition GO:0050890 141 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
purine containing compound catabolic process GO:0072523 112 0.013
vitamin metabolic process GO:0006766 2 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
protein complex biogenesis GO:0070271 201 0.013
oxoacid metabolic process GO:0043436 103 0.013
negative regulation of growth GO:0045926 84 0.013
Fly
guanosine containing compound catabolic process GO:1901069 74 0.013
regulation of growth GO:0040008 233 0.013
Fly
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
eye morphogenesis GO:0048592 260 0.013
regulation of phosphorylation GO:0042325 147 0.013
Fly
multi organism behavior GO:0051705 175 0.013
positive regulation of nucleotide metabolic process GO:0045981 55 0.013
golgi organization GO:0007030 66 0.012
Fly
nucleoside phosphate catabolic process GO:1901292 110 0.012
regulation of cellular component size GO:0032535 98 0.012
Fly
organonitrogen compound catabolic process GO:1901565 128 0.012
nitrogen compound transport GO:0071705 85 0.012
renal system development GO:0072001 72 0.012
Fly
immune response GO:0006955 246 0.012
Fly
embryonic pattern specification GO:0009880 174 0.012
positive regulation of cell motility GO:2000147 3 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
adult behavior GO:0030534 137 0.012
morphogenesis of a polarized epithelium GO:0001738 93 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
Fly
positive regulation of gtpase activity GO:0043547 43 0.012
macromolecule catabolic process GO:0009057 161 0.012
forebrain development GO:0030900 2 0.012
renal tubule morphogenesis GO:0061333 44 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
cell cycle checkpoint GO:0000075 95 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
chromosome organization GO:0051276 360 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
motor neuron axon guidance GO:0008045 58 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
sensory perception of taste GO:0050909 25 0.012
gene silencing GO:0016458 138 0.012
intracellular protein transport GO:0006886 104 0.012
positive regulation of molecular function GO:0044093 136 0.012
Fly
immune effector process GO:0002252 98 0.012
actin filament based process GO:0030029 220 0.012
male courtship behavior GO:0008049 63 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
developmental programmed cell death GO:0010623 138 0.012
regulation of neuron differentiation GO:0045664 103 0.011
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
vesicle localization GO:0051648 55 0.011
cellular protein localization GO:0034613 160 0.011
rna localization GO:0006403 115 0.011
regulation of protein modification process GO:0031399 112 0.011
Fly
sensory organ morphogenesis GO:0090596 260 0.011
endomembrane system organization GO:0010256 119 0.011
Fly
regulation of neurogenesis GO:0050767 158 0.011
Fly
anterior posterior pattern specification GO:0009952 136 0.011
response to organic cyclic compound GO:0014070 89 0.011
learning GO:0007612 75 0.011
wnt signaling pathway GO:0016055 98 0.011
response to organonitrogen compound GO:0010243 75 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
midgut development GO:0007494 23 0.011
single organism cell adhesion GO:0098602 47 0.011
regulation of cell projection organization GO:0031344 92 0.011
Fly
chromatin modification GO:0016568 147 0.011
meiotic cell cycle GO:0051321 171 0.011
peripheral nervous system development GO:0007422 52 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
proteolysis GO:0006508 192 0.011
establishment of vesicle localization GO:0051650 51 0.011
anterior posterior axis specification GO:0009948 109 0.011
locomotory behavior GO:0007626 176 0.011
meiotic cell cycle process GO:1903046 132 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
telencephalon development GO:0021537 2 0.011
malpighian tubule development GO:0072002 64 0.011
mitotic spindle organization GO:0007052 220 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
Fly
positive regulation of nucleotide catabolic process GO:0030813 46 0.011
eggshell formation GO:0030703 105 0.011
embryonic axis specification GO:0000578 107 0.010
secretion GO:0046903 109 0.010
sensory perception of mechanical stimulus GO:0050954 72 0.010
gtp metabolic process GO:0046039 72 0.010
retina development in camera type eye GO:0060041 4 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
mesoderm development GO:0007498 78 0.010
Fly
male gamete generation GO:0048232 201 0.010
synaptic vesicle localization GO:0097479 53 0.010
learning or memory GO:0007611 141 0.010
regulation of purine nucleotide catabolic process GO:0033121 48 0.010
regulation of cell size GO:0008361 63 0.010
Fly
oocyte development GO:0048599 124 0.010
cytokinesis GO:0000910 90 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
chorion containing eggshell formation GO:0007304 105 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
positive regulation of exocytosis GO:0045921 4 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010

Ret disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
cardiovascular system disease DOID:1287 0 0.016
nervous system disease DOID:863 0 0.011