Drosophila melanogaster

54 known processes

Fancd2 (Dmel_CG17269)

CG17269 gene product from transcript CG17269-RA

(Aliases: dmFANCD2,Dmel\CG17269,FANCD2,CG31192,CG17269,CG31194)

Fancd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 223 0.416
dna repair GO:0006281 54 0.299
dna metabolic process GO:0006259 227 0.285
spindle organization GO:0007051 253 0.171
mitotic spindle organization GO:0007052 220 0.126
negative regulation of cellular biosynthetic process GO:0031327 277 0.114
chromosome organization GO:0051276 360 0.106
regulation of cell differentiation GO:0045595 302 0.086
protein modification by small protein conjugation or removal GO:0070647 106 0.083
mrna metabolic process GO:0016071 124 0.081
negative regulation of biosynthetic process GO:0009890 277 0.081
protein modification process GO:0036211 438 0.080
nuclear division GO:0000280 332 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.075
regulation of mitotic cell cycle GO:0007346 190 0.072
organic substance catabolic process GO:1901575 308 0.072
negative regulation of gene expression GO:0010629 387 0.072
eye development GO:0001654 323 0.068
nucleobase containing compound catabolic process GO:0034655 165 0.067
regulation of multicellular organismal development GO:2000026 414 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.065
cellular protein modification process GO:0006464 438 0.065
negative regulation of cellular metabolic process GO:0031324 382 0.060
negative regulation of nucleic acid templated transcription GO:1903507 240 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
regulation of cell cycle GO:0051726 291 0.055
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.055
aromatic compound catabolic process GO:0019439 166 0.053
tube development GO:0035295 244 0.051
cell proliferation GO:0008283 299 0.050
programmed cell death GO:0012501 257 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
positive regulation of gene expression GO:0010628 290 0.049
response to biotic stimulus GO:0009607 294 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.047
mitotic g2 m transition checkpoint GO:0044818 70 0.047
death GO:0016265 284 0.046
gene silencing GO:0016458 138 0.046
negative regulation of transcription dna templated GO:0045892 237 0.046
cellular nitrogen compound catabolic process GO:0044270 165 0.045
response to external biotic stimulus GO:0043207 293 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.044
organic cyclic compound catabolic process GO:1901361 168 0.043
regulation of response to stress GO:0080134 200 0.043
immune response GO:0006955 246 0.043
chromatin organization GO:0006325 207 0.042
heterocycle catabolic process GO:0046700 166 0.041
cellular macromolecule catabolic process GO:0044265 136 0.041
homeostatic process GO:0042592 199 0.040
positive regulation of transcription dna templated GO:0045893 266 0.040
negative regulation of rna metabolic process GO:0051253 251 0.040
catabolic process GO:0009056 409 0.040
negative regulation of mitotic cell cycle GO:0045930 109 0.040
male gamete generation GO:0048232 201 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.038
endocytosis GO:0006897 310 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.038
brain development GO:0007420 120 0.038
negative regulation of cell cycle process GO:0010948 109 0.038
taxis GO:0042330 304 0.037
negative regulation of cell cycle GO:0045786 116 0.037
negative regulation of rna biosynthetic process GO:1902679 240 0.037
vesicle mediated transport GO:0016192 381 0.037
appendage morphogenesis GO:0035107 397 0.037
immune system process GO:0002376 347 0.037
tissue morphogenesis GO:0048729 297 0.036
small molecule metabolic process GO:0044281 305 0.035
neurological system process GO:0050877 358 0.035
regulation of cell cycle process GO:0010564 181 0.035
eye photoreceptor cell differentiation GO:0001754 145 0.034
eye morphogenesis GO:0048592 260 0.034
organelle fission GO:0048285 340 0.034
embryonic development via the syncytial blastoderm GO:0001700 148 0.034
axon development GO:0061564 297 0.034
epithelial cell development GO:0002064 274 0.034
positive regulation of response to stimulus GO:0048584 323 0.033
regulation of mitotic cell cycle phase transition GO:1901990 130 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
organelle assembly GO:0070925 198 0.033
regulation of protein metabolic process GO:0051246 256 0.033
negative regulation of gene expression epigenetic GO:0045814 77 0.032
dna conformation change GO:0071103 105 0.032
chromatin silencing GO:0006342 76 0.032
sensory organ morphogenesis GO:0090596 260 0.031
response to other organism GO:0051707 293 0.031
intracellular signal transduction GO:0035556 300 0.031
cellular catabolic process GO:0044248 372 0.031
compound eye development GO:0048749 307 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
negative regulation of cell cycle phase transition GO:1901988 103 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
protein ubiquitination GO:0016567 70 0.030
cell death GO:0008219 279 0.029
compound eye morphogenesis GO:0001745 249 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.029
negative regulation of response to stimulus GO:0048585 258 0.029
regulation of organelle organization GO:0033043 196 0.029
positive regulation of cell communication GO:0010647 250 0.029
response to abiotic stimulus GO:0009628 341 0.029
mitotic dna integrity checkpoint GO:0044774 75 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
macromolecular complex assembly GO:0065003 256 0.028
body morphogenesis GO:0010171 2 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
head development GO:0060322 135 0.028
multi organism behavior GO:0051705 175 0.028
positive regulation of rna metabolic process GO:0051254 271 0.027
appendage development GO:0048736 401 0.027
dna packaging GO:0006323 91 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
mitotic nuclear division GO:0007067 213 0.027
positive regulation of biosynthetic process GO:0009891 316 0.027
mitotic dna damage checkpoint GO:0044773 74 0.026
protein modification by small protein conjugation GO:0032446 79 0.026
mrna processing GO:0006397 104 0.026
negative regulation of signaling GO:0023057 219 0.026
macromolecule catabolic process GO:0009057 161 0.025
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
mrna splicing via spliceosome GO:0000398 73 0.025
apoptotic process GO:0006915 159 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
histone modification GO:0016570 106 0.024
open tracheal system development GO:0007424 204 0.024
mitotic cell cycle phase transition GO:0044772 138 0.024
regulation of cell morphogenesis GO:0022604 163 0.024
central nervous system development GO:0007417 201 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
regulation of gene expression epigenetic GO:0040029 128 0.024
exocrine system development GO:0035272 162 0.023
phagocytosis GO:0006909 215 0.023
wing disc morphogenesis GO:0007472 344 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.022
rna processing GO:0006396 147 0.022
developmental growth GO:0048589 280 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
growth GO:0040007 359 0.022
photoreceptor cell differentiation GO:0046530 170 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
positive regulation of signal transduction GO:0009967 223 0.022
regulation of immune system process GO:0002682 176 0.022
nucleotide catabolic process GO:0009166 109 0.022
positive regulation of molecular function GO:0044093 136 0.022
innate immune response GO:0045087 144 0.021
rna catabolic process GO:0006401 37 0.021
establishment of localization in cell GO:0051649 402 0.021
segmentation GO:0035282 207 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
cell cycle phase transition GO:0044770 140 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
salivary gland development GO:0007431 162 0.020
dna integrity checkpoint GO:0031570 81 0.020
single organism biosynthetic process GO:0044711 206 0.020
dendrite development GO:0016358 204 0.020
ovarian follicle cell development GO:0030707 248 0.020
regulation of molecular function GO:0065009 217 0.020
protein complex biogenesis GO:0070271 201 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
actin filament based process GO:0030029 220 0.019
regulation of cell shape GO:0008360 113 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
lateral inhibition GO:0046331 206 0.019
rna splicing via transesterification reactions GO:0000375 73 0.019
proteolysis GO:0006508 192 0.019
camera type eye development GO:0043010 4 0.019
protein dna complex subunit organization GO:0071824 86 0.019
regulation of nervous system development GO:0051960 248 0.019
organic acid metabolic process GO:0006082 103 0.019
cellular protein localization GO:0034613 160 0.018
regulation of hydrolase activity GO:0051336 97 0.018
regionalization GO:0003002 416 0.018
meiotic cell cycle GO:0051321 171 0.018
axonogenesis GO:0007409 290 0.018
protein complex assembly GO:0006461 200 0.018
oxoacid metabolic process GO:0043436 103 0.018
tube morphogenesis GO:0035239 191 0.018
protein dna complex assembly GO:0065004 63 0.018
regulation of innate immune response GO:0045088 71 0.018
phosphorylation GO:0016310 294 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
cell division GO:0051301 248 0.017
mitotic g2 dna damage checkpoint GO:0007095 69 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
g2 dna damage checkpoint GO:0031572 69 0.017
negative regulation of cell communication GO:0010648 223 0.017
defense response to bacterium GO:0042742 178 0.017
epithelial cell differentiation GO:0030855 322 0.017
dna damage checkpoint GO:0000077 78 0.017
organophosphate catabolic process GO:0046434 112 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
organonitrogen compound catabolic process GO:1901565 128 0.016
neuron projection guidance GO:0097485 241 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
positive regulation of signaling GO:0023056 243 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
regulation of cell cycle phase transition GO:1901987 130 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
chemotaxis GO:0006935 249 0.016
organophosphate metabolic process GO:0019637 195 0.016
photoreceptor cell development GO:0042461 96 0.016
cuticle development GO:0042335 86 0.016
actin cytoskeleton organization GO:0030036 206 0.015
neuron recognition GO:0008038 101 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
regulation of cell development GO:0060284 215 0.015
axon guidance GO:0007411 233 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
purine containing compound catabolic process GO:0072523 112 0.015
regulation of rna splicing GO:0043484 69 0.015
posttranscriptional gene silencing GO:0016441 46 0.015
dendrite morphogenesis GO:0048813 199 0.015
spindle assembly GO:0051225 80 0.015
eggshell formation GO:0030703 105 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
cellular response to organic substance GO:0071310 132 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
single organism catabolic process GO:0044712 228 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
spermatogenesis GO:0007283 200 0.015
ras protein signal transduction GO:0007265 88 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
muscle structure development GO:0061061 224 0.014
regulation of localization GO:0032879 275 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
regulation of mrna processing GO:0050684 71 0.014
regulation of defense response GO:0031347 102 0.014
regulation of cell death GO:0010941 173 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
response to organic substance GO:0010033 284 0.014
response to bacterium GO:0009617 198 0.014
rna splicing GO:0008380 83 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
notch signaling pathway GO:0007219 120 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
protein transport GO:0015031 155 0.014
response to lipopolysaccharide GO:0032496 4 0.013
developmental programmed cell death GO:0010623 138 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
cellular macromolecule localization GO:0070727 220 0.013
cellular homeostasis GO:0019725 80 0.013
axis specification GO:0009798 167 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.013
alternative mrna splicing via spliceosome GO:0000380 60 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
cell motility GO:0048870 251 0.013
respiratory system development GO:0060541 213 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
double strand break repair GO:0006302 26 0.013
cell recognition GO:0008037 102 0.013
nucleoside catabolic process GO:0009164 112 0.013
nucleotide metabolic process GO:0009117 161 0.013
salivary gland morphogenesis GO:0007435 145 0.013
chromatin modification GO:0016568 147 0.013
cellular protein complex assembly GO:0043623 71 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
regulation of apoptotic process GO:0042981 130 0.013
actin filament organization GO:0007015 126 0.013
defense response to other organism GO:0098542 225 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
chromosome segregation GO:0007059 157 0.013
regulation of gene silencing GO:0060968 63 0.012
cellular ketone metabolic process GO:0042180 24 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
gland morphogenesis GO:0022612 145 0.012
localization of cell GO:0051674 257 0.012
stem cell proliferation GO:0072089 88 0.012
regulation of cellular response to stress GO:0080135 89 0.012
organic substance transport GO:0071702 257 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
cellular amine metabolic process GO:0044106 12 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
positive regulation of catabolic process GO:0009896 105 0.012
single organism behavior GO:0044708 391 0.012
nucleoside metabolic process GO:0009116 127 0.012
developmental maturation GO:0021700 172 0.012
peptidyl amino acid modification GO:0018193 105 0.012
spermatid development GO:0007286 98 0.012
regulation of microtubule based process GO:0032886 49 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
cell migration GO:0016477 238 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
protein localization GO:0008104 284 0.012
regulation of chromatin silencing GO:0031935 36 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
mrna catabolic process GO:0006402 33 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
purine nucleotide catabolic process GO:0006195 109 0.011
positive regulation of developmental process GO:0051094 143 0.011
rna 3 end processing GO:0031123 45 0.011
female meiotic division GO:0007143 70 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
purine containing compound metabolic process GO:0072521 155 0.011
protein catabolic process GO:0030163 101 0.011
defense response GO:0006952 300 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
cell cycle checkpoint GO:0000075 95 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
sister chromatid segregation GO:0000819 92 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
eye photoreceptor cell development GO:0042462 81 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
determination of adult lifespan GO:0008340 137 0.011
organelle localization GO:0051640 148 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
chitin based cuticle development GO:0040003 49 0.011
regulation of system process GO:0044057 36 0.011
chromatin remodeling GO:0006338 72 0.010
negative regulation of signal transduction GO:0009968 206 0.010
aging GO:0007568 143 0.010
gland development GO:0048732 191 0.010
response to temperature stimulus GO:0009266 106 0.010
chromatin assembly or disassembly GO:0006333 52 0.010
regulation of embryonic development GO:0045995 68 0.010
histone exchange GO:0043486 21 0.010
regulation of cell proliferation GO:0042127 163 0.010
compound eye photoreceptor development GO:0042051 78 0.010
amine metabolic process GO:0009308 12 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
regulation of catalytic activity GO:0050790 185 0.010
regulation of immune response GO:0050776 118 0.010
anatomical structure homeostasis GO:0060249 97 0.010
mitotic cell cycle embryonic GO:0045448 38 0.010
gene silencing by rna GO:0031047 57 0.010
connective tissue development GO:0061448 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
regulation of catabolic process GO:0009894 170 0.010

Fancd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.012