Drosophila melanogaster

0 known processes

TwdlE (Dmel_CG14534)

TweedleE

(Aliases: CG14534,Dmel\CG14534)

TwdlE biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chitin based cuticle development GO:0040003 49 0.898
Fly
muscle structure development GO:0061061 224 0.744
negative regulation of cellular metabolic process GO:0031324 382 0.463
cuticle development GO:0042335 86 0.389
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.307
single organism catabolic process GO:0044712 228 0.159
response to abiotic stimulus GO:0009628 341 0.153
body morphogenesis GO:0010171 2 0.149
negative regulation of gene expression GO:0010629 387 0.148
immune system process GO:0002376 347 0.147
small molecule metabolic process GO:0044281 305 0.138
cellular response to reactive oxygen species GO:0034614 14 0.097
organonitrogen compound metabolic process GO:1901564 318 0.097
proteolysis GO:0006508 192 0.093
wound healing GO:0042060 75 0.081
regulation of cell cycle GO:0051726 291 0.080
response to oxygen containing compound GO:1901700 200 0.079
cellular response to radiation GO:0071478 52 0.079
organic substance transport GO:0071702 257 0.078
positive regulation of cellular biosynthetic process GO:0031328 316 0.077
positive regulation of biosynthetic process GO:0009891 316 0.076
positive regulation of nucleic acid templated transcription GO:1903508 266 0.075
meiotic nuclear division GO:0007126 151 0.073
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.072
salivary gland development GO:0007431 162 0.067
brain development GO:0007420 120 0.066
intracellular signal transduction GO:0035556 300 0.062
cellular catabolic process GO:0044248 372 0.062
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.061
catabolic process GO:0009056 409 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.057
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.057
regulation of cell death GO:0010941 173 0.055
endomembrane system organization GO:0010256 119 0.053
salivary gland morphogenesis GO:0007435 145 0.049
carboxylic acid metabolic process GO:0019752 92 0.049
cellular response to external stimulus GO:0071496 66 0.047
negative regulation of cellular biosynthetic process GO:0031327 277 0.046
negative regulation of cell cycle GO:0045786 116 0.045
cellular response to extracellular stimulus GO:0031668 64 0.044
cellular amino acid metabolic process GO:0006520 61 0.043
response to light stimulus GO:0009416 124 0.043
homeostatic process GO:0042592 199 0.043
regulation of apoptotic signaling pathway GO:2001233 10 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
instar larval development GO:0002168 55 0.040
post embryonic appendage morphogenesis GO:0035120 385 0.039
protein localization GO:0008104 284 0.038
cell death GO:0008219 279 0.038
positive regulation of gene expression GO:0010628 290 0.038
embryo development ending in birth or egg hatching GO:0009792 152 0.037
cilium organization GO:0044782 41 0.037
organonitrogen compound catabolic process GO:1901565 128 0.036
organic acid metabolic process GO:0006082 103 0.035
leg disc development GO:0035218 92 0.034
imaginal disc derived appendage development GO:0048737 399 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
positive regulation of transcription dna templated GO:0045893 266 0.033
microtubule bundle formation GO:0001578 27 0.032
regulation of protein metabolic process GO:0051246 256 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.032
nuclear division GO:0000280 332 0.031
regionalization GO:0003002 416 0.031
cilium morphogenesis GO:0060271 39 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.031
response to organic substance GO:0010033 284 0.030
negative regulation of nucleic acid templated transcription GO:1903507 240 0.030
cellular ketone metabolic process GO:0042180 24 0.029
camera type eye development GO:0043010 4 0.029
positive regulation of macromolecule metabolic process GO:0010604 405 0.029
mitotic dna damage checkpoint GO:0044773 74 0.028
defense response GO:0006952 300 0.027
forebrain development GO:0030900 2 0.026
secondary metabolic process GO:0019748 75 0.026
regulation of response to external stimulus GO:0032101 115 0.026
response to ethanol GO:0045471 59 0.026
chromosome organization GO:0051276 360 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
epithelial cell migration open tracheal system GO:0007427 32 0.025
regulation of intracellular signal transduction GO:1902531 236 0.024
response to wounding GO:0009611 94 0.024
appendage development GO:0048736 401 0.024
regulation of cell differentiation GO:0045595 302 0.024
hormone catabolic process GO:0042447 3 0.024
response to radiation GO:0009314 155 0.023
spermatid development GO:0007286 98 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
anion homeostasis GO:0055081 3 0.023
developmental programmed cell death GO:0010623 138 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
eye development GO:0001654 323 0.022
regulation of cell cycle phase transition GO:1901987 130 0.022
cell motility GO:0048870 251 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.021
spinal cord development GO:0021510 1 0.021
telencephalon development GO:0021537 2 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.020
male gamete generation GO:0048232 201 0.020
connective tissue development GO:0061448 3 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
leg disc morphogenesis GO:0007478 80 0.020
malpighian tubule development GO:0072002 64 0.020
amine metabolic process GO:0009308 12 0.019
death GO:0016265 284 0.019
dna metabolic process GO:0006259 227 0.018
defense response to bacterium GO:0042742 178 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
eye morphogenesis GO:0048592 260 0.018
regulation of cell cycle process GO:0010564 181 0.018
embryonic development via the syncytial blastoderm GO:0001700 148 0.018
cellular response to nutrient levels GO:0031669 62 0.018
dna damage checkpoint GO:0000077 78 0.018
cellular response to dna damage stimulus GO:0006974 223 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
regulation of immune system process GO:0002682 176 0.017
response to mechanical stimulus GO:0009612 28 0.017
cellular protein catabolic process GO:0044257 83 0.017
programmed cell death GO:0012501 257 0.016
cell projection assembly GO:0030031 94 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
response to fungus GO:0009620 50 0.016
actin filament based process GO:0030029 220 0.016
negative regulation of transcription dna templated GO:0045892 237 0.016
central nervous system development GO:0007417 201 0.016
proteasomal protein catabolic process GO:0010498 59 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
autophagy GO:0006914 108 0.016
amino sugar catabolic process GO:0046348 3 0.016
eye photoreceptor cell development GO:0042462 81 0.015
oocyte anterior posterior axis specification GO:0007314 72 0.015
gtp catabolic process GO:0006184 72 0.015
cellular response to abiotic stimulus GO:0071214 58 0.015
protein transport GO:0015031 155 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
regulation of protein stability GO:0031647 43 0.015
head development GO:0060322 135 0.015
lymph gland development GO:0048542 28 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
organic substance catabolic process GO:1901575 308 0.014
compound eye photoreceptor development GO:0042051 78 0.014
apoptotic signaling pathway GO:0097190 27 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
cell migration GO:0016477 238 0.014
regulation of catalytic activity GO:0050790 185 0.013
phagocytosis GO:0006909 215 0.013
synapse assembly GO:0007416 143 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.013
cellular protein modification process GO:0006464 438 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.013
biological adhesion GO:0022610 138 0.013
sperm axoneme assembly GO:0007288 13 0.013
macromolecule catabolic process GO:0009057 161 0.013
pigment metabolic process GO:0042440 84 0.013
negative regulation of response to stimulus GO:0048585 258 0.012
sensory perception GO:0007600 196 0.012
neurological system process GO:0050877 358 0.012
response to copper ion GO:0046688 4 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
gliogenesis GO:0042063 80 0.012
cellular amine metabolic process GO:0044106 12 0.012
negative regulation of catabolic process GO:0009895 36 0.012
endocytosis GO:0006897 310 0.012
photoreceptor cell development GO:0042461 96 0.012
regulation of cellular component biogenesis GO:0044087 201 0.011
vesicle mediated transport GO:0016192 381 0.011
positive regulation of cell communication GO:0010647 250 0.011
neural precursor cell proliferation GO:0061351 75 0.011
gland development GO:0048732 191 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
intracellular transport GO:0046907 228 0.011
regulation of cell size GO:0008361 63 0.011
response to extracellular stimulus GO:0009991 116 0.011
synaptic transmission GO:0007268 288 0.011
regulation of glial cell differentiation GO:0045685 1 0.011
multi multicellular organism process GO:0044706 123 0.011
respiratory system development GO:0060541 213 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
sensory organ morphogenesis GO:0090596 260 0.011
regulation of apoptotic process GO:0042981 130 0.011
cellular response to oxidative stress GO:0034599 28 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
regulation of chromatin silencing GO:0031935 36 0.011
centrosome organization GO:0051297 163 0.011
eye antennal disc morphogenesis GO:0007455 34 0.011
intracellular protein transport GO:0006886 104 0.011
secondary metabolite biosynthetic process GO:0044550 24 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
dendrite morphogenesis GO:0048813 199 0.010
monocarboxylic acid transport GO:0015718 3 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
regulation of protein localization GO:0032880 76 0.010
regulation of nervous system development GO:0051960 248 0.010
single organism intracellular transport GO:1902582 207 0.010
dendrite development GO:0016358 204 0.010
ion transport GO:0006811 145 0.010
regulation of response to stress GO:0080134 200 0.010
chromatin silencing GO:0006342 76 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010

TwdlE disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.039
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.017
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cardiovascular system disease DOID:1287 0 0.010