Drosophila melanogaster

2 known processes

Pgi (Dmel_CG8251)

Phosphoglucose isomerase

(Aliases: GPI,pgi,Dmel\CG8251,PGI,CG8251,Gpi)

Pgi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nad metabolic process GO:0019674 1 0.851
pyruvate metabolic process GO:0006090 7 0.610
oxoacid metabolic process GO:0043436 103 0.459
monocarboxylic acid metabolic process GO:0032787 29 0.422
carboxylic acid metabolic process GO:0019752 92 0.309
acetaldehyde metabolic process GO:0006117 5 0.268
organic acid metabolic process GO:0006082 103 0.267
small molecule metabolic process GO:0044281 305 0.265
oxidation reduction process GO:0055114 123 0.204
organonitrogen compound biosynthetic process GO:1901566 117 0.180
organonitrogen compound metabolic process GO:1901564 318 0.178
catabolic process GO:0009056 409 0.139
nicotinamide nucleotide metabolic process GO:0046496 2 0.134
single organism carbohydrate metabolic process GO:0044723 72 0.115
negative regulation of biosynthetic process GO:0009890 277 0.111
nucleoside phosphate biosynthetic process GO:1901293 34 0.109
organic substance catabolic process GO:1901575 308 0.105
organophosphate metabolic process GO:0019637 195 0.104
pyridine nucleotide metabolic process GO:0019362 2 0.100
carbohydrate metabolic process GO:0005975 82 0.092
single organism biosynthetic process GO:0044711 206 0.088
single organism catabolic process GO:0044712 228 0.083
response to organic substance GO:0010033 284 0.082
generation of precursor metabolites and energy GO:0006091 42 0.082
carbohydrate catabolic process GO:0016052 7 0.076
nucleoside phosphate metabolic process GO:0006753 162 0.073
nucleobase containing small molecule metabolic process GO:0055086 174 0.073
cellular catabolic process GO:0044248 372 0.073
immune response GO:0006955 246 0.071
energy derivation by oxidation of organic compounds GO:0015980 32 0.066
thioester biosynthetic process GO:0035384 2 0.062
carbohydrate derivative biosynthetic process GO:1901137 85 0.061
response to oxygen containing compound GO:1901700 200 0.056
tube morphogenesis GO:0035239 191 0.056
male gamete generation GO:0048232 201 0.056
pyridine containing compound metabolic process GO:0072524 3 0.054
nucleotide metabolic process GO:0009117 161 0.052
response to insulin GO:0032868 29 0.050
carboxylic acid catabolic process GO:0046395 16 0.048
aging GO:0007568 143 0.048
multicellular organismal aging GO:0010259 140 0.047
purine nucleoside metabolic process GO:0042278 127 0.047
somatic muscle development GO:0007525 66 0.044
response to organic cyclic compound GO:0014070 89 0.044
ribonucleoside biosynthetic process GO:0042455 3 0.044
regulation of cellular catabolic process GO:0031329 157 0.042
single organism carbohydrate catabolic process GO:0044724 7 0.041
monocarboxylic acid catabolic process GO:0072329 10 0.040
response to ethanol GO:0045471 59 0.039
peptide metabolic process GO:0006518 80 0.039
neuroblast proliferation GO:0007405 74 0.038
purine containing compound metabolic process GO:0072521 155 0.038
determination of adult lifespan GO:0008340 137 0.037
small molecule biosynthetic process GO:0044283 37 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.035
glycolytic process GO:0006096 6 0.035
response to glucose GO:0009749 2 0.035
innate immune response GO:0045087 144 0.034
homeostatic process GO:0042592 199 0.032
response to external biotic stimulus GO:0043207 293 0.032
larval development GO:0002164 104 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.029
striated muscle myosin thick filament assembly GO:0071688 3 0.027
nucleoside metabolic process GO:0009116 127 0.027
compound eye development GO:0048749 307 0.026
cellular protein complex assembly GO:0043623 71 0.026
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
ribonucleoside metabolic process GO:0009119 127 0.025
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
carbohydrate biosynthetic process GO:0016051 17 0.025
lateral inhibition GO:0046331 206 0.024
nadh metabolic process GO:0006734 1 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
syncytium formation GO:0006949 43 0.023
phagocytosis GO:0006909 215 0.023
oxidoreduction coenzyme metabolic process GO:0006733 2 0.023
spermatogenesis GO:0007283 200 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
acyl coa metabolic process GO:0006637 3 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
lipid metabolic process GO:0006629 121 0.022
cellular carbohydrate metabolic process GO:0044262 22 0.021
myoblast fusion GO:0007520 43 0.021
response to hexose GO:0009746 3 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
response to heat GO:0009408 63 0.021
regulation of nervous system development GO:0051960 248 0.021
regulation of cell development GO:0060284 215 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
glucan biosynthetic process GO:0009250 2 0.019
digestive system development GO:0055123 149 0.019
positive regulation of cellular catabolic process GO:0031331 95 0.019
glucose metabolic process GO:0006006 5 0.019
cellular response to organic substance GO:0071310 132 0.019
cellular response to peptide hormone stimulus GO:0071375 28 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
organophosphate biosynthetic process GO:0090407 46 0.018
cell aging GO:0007569 2 0.018
death GO:0016265 284 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
cellular response to insulin stimulus GO:0032869 28 0.018
response to biotic stimulus GO:0009607 294 0.017
cellular homeostasis GO:0019725 80 0.017
gastrulation GO:0007369 70 0.017
organelle assembly GO:0070925 198 0.017
cellular lipid metabolic process GO:0044255 83 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
neural precursor cell proliferation GO:0061351 75 0.017
regulation of translation GO:0006417 56 0.017
nucleoside biosynthetic process GO:0009163 3 0.016
immune system process GO:0002376 347 0.016
positive regulation of lipid metabolic process GO:0045834 4 0.016
monosaccharide metabolic process GO:0005996 9 0.016
cell maturation GO:0048469 144 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
regulation of multicellular organismal development GO:2000026 414 0.015
response to bacterium GO:0009617 198 0.015
regulation of organelle organization GO:0033043 196 0.015
cell death GO:0008219 279 0.015
atp biosynthetic process GO:0006754 2 0.015
actin cytoskeleton organization GO:0030036 206 0.015
negative regulation of protein metabolic process GO:0051248 85 0.014
cellular carbohydrate catabolic process GO:0044275 2 0.014
small molecule catabolic process GO:0044282 21 0.014
developmental growth GO:0048589 280 0.014
phosphatidylinositol mediated signaling GO:0048015 4 0.014
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.014
regulation of cell cycle GO:0051726 291 0.013
cellular amino acid biosynthetic process GO:0008652 9 0.013
sulfur compound metabolic process GO:0006790 59 0.013
ribose phosphate biosynthetic process GO:0046390 28 0.013
lipid biosynthetic process GO:0008610 46 0.013
digestive tract morphogenesis GO:0048546 127 0.013
regulation of growth GO:0040008 233 0.013
regulation of defense response GO:0031347 102 0.013
positive regulation of catabolic process GO:0009896 105 0.013
muscle structure development GO:0061061 224 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of cell differentiation GO:0045595 302 0.012
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.012
purine ribonucleoside biosynthetic process GO:0046129 3 0.012
single organism behavior GO:0044708 391 0.012
protein processing GO:0016485 68 0.012
cellular protein modification process GO:0006464 438 0.012
actin filament based process GO:0030029 220 0.012
defense response GO:0006952 300 0.012
protein maturation GO:0051604 71 0.012
hindbrain development GO:0030902 2 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
translation GO:0006412 69 0.012
phosphorylation GO:0016310 294 0.012
response to other organism GO:0051707 293 0.012
nucleotide biosynthetic process GO:0009165 34 0.011
atp synthesis coupled electron transport GO:0042773 8 0.011
oocyte differentiation GO:0009994 145 0.011
adult locomotory behavior GO:0008344 76 0.011
phosphate ion transmembrane transport GO:0035435 4 0.011
response to peptide hormone GO:0043434 29 0.011
negative regulation of developmental process GO:0051093 201 0.011
nucleoside triphosphate biosynthetic process GO:0009142 2 0.011
regulation of immune system process GO:0002682 176 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
sex differentiation GO:0007548 81 0.011
protein complex biogenesis GO:0070271 201 0.011
amine metabolic process GO:0009308 12 0.011
respiratory electron transport chain GO:0022904 11 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
synaptic transmission GO:0007268 288 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
mitochondrion organization GO:0007005 65 0.010
cellular biogenic amine catabolic process GO:0042402 1 0.010

Pgi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
Human
nervous system disease DOID:863 0 0.041
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011