Drosophila melanogaster

70 known processes

Spn28D (Dmel_CG7219)

Serpin 28D

(Aliases: Dmel\CG7219,Dm-Spn28D,spn28D,CG7219,Spn28Dc)

Spn28D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
secondary metabolic process GO:0019748 75 0.936
phenol containing compound metabolic process GO:0018958 57 0.916
positive regulation of antimicrobial peptide production GO:0002225 28 0.913
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.874
antimicrobial peptide production GO:0002775 46 0.827
antibacterial humoral response GO:0019731 44 0.815
production of molecular mediator of immune response GO:0002440 46 0.808
positive regulation of antimicrobial humoral response GO:0002760 28 0.800
regulation of humoral immune response GO:0002920 51 0.794
peptide metabolic process GO:0006518 80 0.763
positive regulation of immune effector process GO:0002699 28 0.724
organic hydroxy compound metabolic process GO:1901615 83 0.721
response to fungus GO:0009620 50 0.705
defense response to bacterium GO:0042742 178 0.685
positive regulation of cellular amide metabolic process GO:0034250 26 0.677
positive regulation of humoral immune response GO:0002922 28 0.661
pigment metabolic process GO:0042440 84 0.660
antibacterial peptide biosynthetic process GO:0002780 22 0.659
immune system process GO:0002376 347 0.657
regulation of antimicrobial humoral response GO:0002759 50 0.628
organonitrogen compound biosynthetic process GO:1901566 117 0.618
immune response GO:0006955 246 0.594
humoral immune response GO:0006959 117 0.594
antimicrobial humoral response GO:0019730 99 0.589
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.576
innate immune response GO:0045087 144 0.571
regulation of melanization defense response GO:0035007 6 0.552
positive regulation of antibacterial peptide production GO:0002803 20 0.522
peptide biosynthetic process GO:0043043 42 0.522
positive regulation of response to biotic stimulus GO:0002833 31 0.504
regulation of response to biotic stimulus GO:0002831 63 0.498
organonitrogen compound metabolic process GO:1901564 318 0.488
positive regulation of response to external stimulus GO:0032103 44 0.486
defense response to other organism GO:0098542 225 0.485
regulation of production of molecular mediator of immune response GO:0002700 44 0.485
regulation of cellular amide metabolic process GO:0034248 39 0.454
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.453
defense response to gram positive bacterium GO:0050830 41 0.451
immune effector process GO:0002252 98 0.445
positive regulation of melanization defense response GO:0035008 1 0.430
melanin metabolic process GO:0006582 47 0.429
hemolymph coagulation GO:0042381 10 0.416
positive regulation of multi organism process GO:0043902 40 0.393
cellular amide metabolic process GO:0043603 80 0.389
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.385
defense response GO:0006952 300 0.364
response to external biotic stimulus GO:0043207 293 0.360
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.352
toll signaling pathway GO:0008063 25 0.342
regulation of antimicrobial peptide production GO:0002784 44 0.332
amide biosynthetic process GO:0043604 42 0.324
antibacterial peptide production GO:0002778 22 0.307
regulation of response to external stimulus GO:0032101 115 0.305
antimicrobial peptide biosynthetic process GO:0002777 38 0.304
defense response to fungus GO:0050832 48 0.302
toxin metabolic process GO:0009404 2 0.299
positive regulation of defense response GO:0031349 59 0.276
positive regulation of defense response to bacterium GO:1900426 23 0.274
regulation of defense response to bacterium GO:1900424 30 0.251
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.251
positive regulation of response to stimulus GO:0048584 323 0.247
dorsal ventral pattern formation GO:0009953 133 0.246
regulation of defense response GO:0031347 102 0.228
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.226
defense response to gram negative bacterium GO:0050829 94 0.213
regulation of immune effector process GO:0002697 52 0.202
open tracheal system development GO:0007424 204 0.201
regulation of secondary metabolic process GO:0043455 7 0.197
regionalization GO:0003002 416 0.193
response to biotic stimulus GO:0009607 294 0.191
regulation of immune system process GO:0002682 176 0.190
regulation of toll signaling pathway GO:0008592 17 0.188
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.188
adult chitin containing cuticle pigmentation GO:0048085 16 0.186
zymogen activation GO:0031638 20 0.186
melanization defense response GO:0035006 45 0.181
chitin based cuticle sclerotization GO:0007593 19 0.165
positive regulation of signal transduction GO:0009967 223 0.165
ovarian follicle cell development GO:0030707 248 0.154
protein maturation GO:0051604 71 0.154
secondary metabolite biosynthetic process GO:0044550 24 0.151
wound healing GO:0042060 75 0.150
small molecule metabolic process GO:0044281 305 0.150
positive regulation of signaling GO:0023056 243 0.149
axis specification GO:0009798 167 0.148
response to wounding GO:0009611 94 0.148
positive regulation of immune response GO:0050778 63 0.146
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.142
response to bacterium GO:0009617 198 0.140
regulation of antibacterial peptide production GO:0002786 22 0.134
pattern recognition receptor signaling pathway GO:0002221 2 0.129
response to other organism GO:0051707 293 0.126
genital disc development GO:0035215 44 0.124
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.120
dorsal ventral axis specification GO:0009950 66 0.118
positive regulation of cellular biosynthetic process GO:0031328 316 0.115
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.112
catecholamine biosynthetic process GO:0042423 3 0.112
striated muscle cell differentiation GO:0051146 90 0.111
positive regulation of cell communication GO:0010647 250 0.111
tissue morphogenesis GO:0048729 297 0.109
positive regulation of immune system process GO:0002684 68 0.109
regulation of multi organism process GO:0043900 131 0.109
vesicle mediated transport GO:0016192 381 0.108
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.107
endocytosis GO:0006897 310 0.098
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.098
phosphorylation GO:0016310 294 0.094
regulation of immune response GO:0050776 118 0.093
regulation of response to stress GO:0080134 200 0.092
mapk cascade GO:0000165 107 0.092
positive regulation of biosynthetic process GO:0009891 316 0.092
border follicle cell migration GO:0007298 113 0.088
epithelial cell differentiation GO:0030855 322 0.086
positive regulation of innate immune response GO:0045089 38 0.086
regulation of cell morphogenesis GO:0022604 163 0.085
negative regulation of response to stimulus GO:0048585 258 0.082
cuticle pigmentation GO:0048067 22 0.080
carboxylic acid metabolic process GO:0019752 92 0.080
appendage morphogenesis GO:0035107 397 0.079
tube development GO:0035295 244 0.079
imaginal disc derived wing morphogenesis GO:0007476 337 0.079
regulation of phosphate metabolic process GO:0019220 210 0.077
respiratory system development GO:0060541 213 0.077
response to organic substance GO:0010033 284 0.077
organic acid metabolic process GO:0006082 103 0.075
negative regulation of signal transduction GO:0009968 206 0.075
regulation of chitin based cuticle tanning GO:0007564 14 0.074
sensory perception of chemical stimulus GO:0007606 116 0.074
negative regulation of developmental process GO:0051093 201 0.074
lateral inhibition GO:0046331 206 0.073
single organism biosynthetic process GO:0044711 206 0.073
regulation of nervous system development GO:0051960 248 0.072
regulation of cuticle pigmentation GO:0048079 16 0.072
amine metabolic process GO:0009308 12 0.072
wing disc morphogenesis GO:0007472 344 0.072
intracellular signal transduction GO:0035556 300 0.071
axon development GO:0061564 297 0.067
oxoacid metabolic process GO:0043436 103 0.066
negative regulation of signaling GO:0023057 219 0.065
stem cell differentiation GO:0048863 117 0.063
negative regulation of cell communication GO:0010648 223 0.061
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.061
regulation of anatomical structure morphogenesis GO:0022603 242 0.061
imaginal disc derived appendage development GO:0048737 399 0.060
peptidoglycan catabolic process GO:0009253 3 0.059
morphogenesis of an epithelium GO:0002009 276 0.059
immune response activating signal transduction GO:0002757 2 0.057
regulation of intracellular signal transduction GO:1902531 236 0.057
imaginal disc derived appendage morphogenesis GO:0035114 395 0.057
sensory perception GO:0007600 196 0.056
germ cell migration GO:0008354 43 0.056
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.056
epithelial cell development GO:0002064 274 0.056
epithelial cell migration GO:0010631 148 0.055
protein modification process GO:0036211 438 0.053
cellular amine metabolic process GO:0044106 12 0.053
cell cell signaling involved in cell fate commitment GO:0045168 210 0.052
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.052
glycosaminoglycan catabolic process GO:0006027 3 0.051
regulation of phosphorus metabolic process GO:0051174 210 0.050
branching morphogenesis of an epithelial tube GO:0048754 45 0.049
post embryonic appendage morphogenesis GO:0035120 385 0.048
axon guidance GO:0007411 233 0.048
neurological system process GO:0050877 358 0.047
appendage development GO:0048736 401 0.047
multicellular organismal aging GO:0010259 140 0.047
tube morphogenesis GO:0035239 191 0.046
phagocytosis GO:0006909 215 0.045
protein processing GO:0016485 68 0.045
connective tissue development GO:0061448 3 0.045
melanotic encapsulation of foreign target GO:0035011 30 0.045
growth GO:0040007 359 0.044
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.043
regulation of mapk cascade GO:0043408 92 0.043
positive regulation of phosphorus metabolic process GO:0010562 139 0.043
regulation of cell differentiation GO:0045595 302 0.043
organonitrogen compound catabolic process GO:1901565 128 0.043
organophosphate metabolic process GO:0019637 195 0.042
negative regulation of intracellular signal transduction GO:1902532 57 0.041
cellular amino acid metabolic process GO:0006520 61 0.041
aging GO:0007568 143 0.041
organic substance catabolic process GO:1901575 308 0.041
muscle organ development GO:0007517 127 0.040
taxis GO:0042330 304 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.040
coagulation GO:0050817 10 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.040
tissue migration GO:0090130 155 0.039
regulation of proteolysis GO:0030162 87 0.038
morphogenesis of a branching epithelium GO:0061138 45 0.038
columnar cuboidal epithelial cell development GO:0002066 249 0.038
muscle structure development GO:0061061 224 0.037
response to lipopolysaccharide GO:0032496 4 0.037
response to oxygen containing compound GO:1901700 200 0.037
epithelial tube morphogenesis GO:0060562 88 0.036
digestive system development GO:0055123 149 0.036
positive regulation of phosphate metabolic process GO:0045937 139 0.036
molting cycle chitin based cuticle GO:0007591 56 0.036
negative regulation of peptide hormone processing GO:0060570 1 0.036
organic substance transport GO:0071702 257 0.036
dopamine biosynthetic process GO:0042416 3 0.035
localization of cell GO:0051674 257 0.035
stress activated mapk cascade GO:0051403 52 0.035
molting cycle process GO:0022404 29 0.034
cellular ketone metabolic process GO:0042180 24 0.034
central nervous system development GO:0007417 201 0.034
sensory perception of smell GO:0007608 80 0.034
muscle cell differentiation GO:0042692 103 0.034
cell adhesion GO:0007155 136 0.034
regulation of multicellular organismal development GO:2000026 414 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
negative regulation of neurogenesis GO:0050768 53 0.034
regulation of body fluid levels GO:0050878 14 0.033
regulation of cell cycle GO:0051726 291 0.032
jnk cascade GO:0007254 50 0.031
regulation of developmental pigmentation GO:0048070 24 0.031
muscle cell development GO:0055001 50 0.031
catechol containing compound biosynthetic process GO:0009713 3 0.031
regulation of anatomical structure size GO:0090066 163 0.031
urogenital system development GO:0001655 72 0.030
vitamin biosynthetic process GO:0009110 1 0.030
cellular lipid metabolic process GO:0044255 83 0.030
positive regulation of intracellular signal transduction GO:1902533 116 0.030
response to temperature stimulus GO:0009266 106 0.030
cellular response to organic substance GO:0071310 132 0.030
response to toxic substance GO:0009636 22 0.030
gonad development GO:0008406 50 0.029
biological adhesion GO:0022610 138 0.029
digestive tract morphogenesis GO:0048546 127 0.029
mesoderm development GO:0007498 78 0.029
regulation of phosphorylation GO:0042325 147 0.029
innate immune response activating signal transduction GO:0002758 2 0.028
response to glucose GO:0009749 2 0.028
cellular catabolic process GO:0044248 372 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
regulation of cellular response to stress GO:0080135 89 0.028
regulation of molecular function GO:0065009 217 0.028
establishment or maintenance of cell polarity GO:0007163 167 0.028
negative regulation of defense response to bacterium GO:1900425 7 0.028
epithelial cell migration open tracheal system GO:0007427 32 0.027
regulation of growth GO:0040008 233 0.027
protein phosphorylation GO:0006468 169 0.027
phenol containing compound biosynthetic process GO:0046189 6 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
salivary gland development GO:0007431 162 0.027
immune response regulating signaling pathway GO:0002764 2 0.027
insecticide catabolic process GO:0046701 1 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
cell division GO:0051301 248 0.026
regulation of protein metabolic process GO:0051246 256 0.026
lauric acid metabolic process GO:0048252 1 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
cell fate determination GO:0001709 91 0.026
cuticle development GO:0042335 86 0.025
response to peptidoglycan GO:0032494 2 0.025
programmed cell death GO:0012501 257 0.025
regulation of developmental growth GO:0048638 174 0.025
regulation of axonogenesis GO:0050770 32 0.025
positive regulation of cell migration GO:0030335 2 0.025
cell motility GO:0048870 251 0.025
negative regulation of cell development GO:0010721 62 0.025
positive regulation of catalytic activity GO:0043085 118 0.024
endomembrane system organization GO:0010256 119 0.024
ethanolamine containing compound metabolic process GO:0042439 4 0.024
developmental programmed cell death GO:0010623 138 0.024
response to extracellular stimulus GO:0009991 116 0.024
nuclear division GO:0000280 332 0.024
response to monosaccharide GO:0034284 4 0.024
response to alcohol GO:0097305 95 0.023
regulation of cell development GO:0060284 215 0.023
regulation of cell size GO:0008361 63 0.023
cardiocyte differentiation GO:0035051 29 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
embryonic morphogenesis GO:0048598 206 0.023
renal system development GO:0072001 72 0.023
negative regulation of cell differentiation GO:0045596 143 0.023
positive regulation of mapk cascade GO:0043410 63 0.023
regulation of cellular component size GO:0032535 98 0.023
compound eye development GO:0048749 307 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
endoderm formation GO:0001706 3 0.022
organic hydroxy compound biosynthetic process GO:1901617 21 0.022
gland morphogenesis GO:0022612 145 0.022
epithelium migration GO:0090132 148 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
tissue death GO:0016271 102 0.022
response to insecticide GO:0017085 14 0.022
peptidoglycan metabolic process GO:0000270 3 0.022
single organism catabolic process GO:0044712 228 0.022
metal ion transport GO:0030001 74 0.022
catabolic process GO:0009056 409 0.022
transmembrane transport GO:0055085 139 0.021
negative regulation of gene expression GO:0010629 387 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
cell fate specification GO:0001708 71 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
regulation of catalytic activity GO:0050790 185 0.020
gene silencing GO:0016458 138 0.020
ocellus pigment biosynthetic process GO:0008055 19 0.020
positive regulation of molecular function GO:0044093 136 0.020
neuron projection guidance GO:0097485 241 0.020
antifungal humoral response GO:0019732 12 0.020
regulation of response to wounding GO:1903034 19 0.019
exocrine system development GO:0035272 162 0.019
salivary gland morphogenesis GO:0007435 145 0.019
positive regulation of phosphorylation GO:0042327 87 0.019
camera type eye development GO:0043010 4 0.019
chorion containing eggshell formation GO:0007304 105 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
negative regulation of growth GO:0045926 84 0.019
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.019
establishment of localization in cell GO:0051649 402 0.019
striated muscle cell development GO:0055002 50 0.019
regulation of protein serine threonine kinase activity GO:0071900 25 0.019
xenobiotic catabolic process GO:0042178 1 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
gastrulation GO:0007369 70 0.019
small molecule biosynthetic process GO:0044283 37 0.018
regulation of localization GO:0032879 275 0.018
negative regulation of nervous system development GO:0051961 92 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
developmental growth involved in morphogenesis GO:0060560 65 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
regulation of neuron differentiation GO:0045664 103 0.018
regulation of neurogenesis GO:0050767 158 0.018
lipid metabolic process GO:0006629 121 0.018
secretion GO:0046903 109 0.018
chemosensory behavior GO:0007635 106 0.017
positive regulation of gene expression GO:0010628 290 0.017
eye development GO:0001654 323 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
anion homeostasis GO:0055081 3 0.017
axonogenesis GO:0007409 290 0.017
positive regulation of cell motility GO:2000147 3 0.017
peptidyl tyrosine phosphorylation GO:0018108 24 0.017
polyol biosynthetic process GO:0046173 3 0.017
response to sterol GO:0036314 34 0.017
apoptotic process GO:0006915 159 0.017
regulation of protein kinase activity GO:0045859 51 0.017
organelle fission GO:0048285 340 0.017
regulation of protein modification process GO:0031399 112 0.017
toxin catabolic process GO:0009407 1 0.017
regulation of cell substrate adhesion GO:0010810 2 0.017
cellular response to endogenous stimulus GO:0071495 80 0.017
response to organophosphorus GO:0046683 2 0.017
cellular protein modification process GO:0006464 438 0.016
establishment of planar polarity GO:0001736 87 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.016
response to copper ion GO:0046688 4 0.016
ion transport GO:0006811 145 0.016
proteolysis GO:0006508 192 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
negative regulation of cell cycle GO:0045786 116 0.016
regulation of transferase activity GO:0051338 58 0.016
response to abiotic stimulus GO:0009628 341 0.016
response to light stimulus GO:0009416 124 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.015
activation of innate immune response GO:0002218 4 0.015
cell death GO:0008219 279 0.015
molting cycle GO:0042303 56 0.015
autophagic cell death GO:0048102 83 0.015
actin filament based process GO:0030029 220 0.015
digestive tract development GO:0048565 149 0.015
regulation of nucleotide catabolic process GO:0030811 48 0.015
ameboidal type cell migration GO:0001667 151 0.015
adult behavior GO:0030534 137 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
regulation of kinase activity GO:0043549 53 0.015
compound eye morphogenesis GO:0001745 249 0.015
peptidyl tyrosine modification GO:0018212 24 0.015
hemostasis GO:0007599 10 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
chromosome segregation GO:0007059 157 0.015
positive regulation of protein deacetylation GO:0090312 2 0.015
morphogenesis of a polarized epithelium GO:0001738 93 0.014
ovarian follicle cell migration GO:0007297 121 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
mitotic nuclear division GO:0007067 213 0.014
regulation of programmed cell death GO:0043067 152 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
developmental growth GO:0048589 280 0.014
cellular response to hexose stimulus GO:0071331 1 0.014
negative regulation of defense response GO:0031348 35 0.014
pyridine containing compound metabolic process GO:0072524 3 0.014
female meiotic division GO:0007143 70 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
fatty acid elongation GO:0030497 3 0.014
body morphogenesis GO:0010171 2 0.014
regulation of transport GO:0051049 181 0.014
positive regulation of histone deacetylation GO:0031065 2 0.014
determination of adult lifespan GO:0008340 137 0.014
regulation of protein deacetylation GO:0090311 2 0.014
kidney development GO:0001822 3 0.014
regulation of lipid transport GO:0032368 3 0.013
developmental pigmentation GO:0048066 68 0.013
macromolecule catabolic process GO:0009057 161 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.013
asymmetric stem cell division GO:0098722 49 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
actin cytoskeleton organization GO:0030036 206 0.013
very long chain fatty acid metabolic process GO:0000038 4 0.013
single organism cell adhesion GO:0098602 47 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
anesthesia resistant memory GO:0007615 6 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
regulation of cell shape GO:0008360 113 0.013
terminal branching open tracheal system GO:0007430 17 0.013
development of primary sexual characteristics GO:0045137 50 0.013
peptide hormone processing GO:0016486 2 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
muscle fiber development GO:0048747 12 0.013
stem cell division GO:0017145 69 0.013
response to decreased oxygen levels GO:0036293 58 0.013
sex differentiation GO:0007548 81 0.013
macromolecular complex assembly GO:0065003 256 0.013
cell cycle arrest GO:0007050 4 0.013
positive regulation of protein phosphorylation GO:0001934 34 0.013
response to nutrient levels GO:0031667 114 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
developmental maturation GO:0021700 172 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.013
alcohol metabolic process GO:0006066 25 0.013
negative regulation of epithelial cell proliferation GO:0050680 4 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of hemocyte differentiation GO:0045610 22 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
negative regulation of proteolysis GO:0045861 31 0.012
retina development in camera type eye GO:0060041 4 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
chemotaxis GO:0006935 249 0.012
protein targeting GO:0006605 64 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
homeostatic process GO:0042592 199 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
regulation of innate immune response GO:0045088 71 0.012
secondary metabolite catabolic process GO:0090487 1 0.012
hyperosmotic salinity response GO:0042538 1 0.012
regulation of wound healing GO:0061041 13 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
olfactory learning GO:0008355 56 0.012
cardiovascular system development GO:0072358 82 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
single organism intracellular transport GO:1902582 207 0.012
cytoplasmic transport GO:0016482 130 0.012
long chain fatty acid metabolic process GO:0001676 3 0.012
cell cycle checkpoint GO:0000075 95 0.012
response to organic cyclic compound GO:0014070 89 0.012
gliogenesis GO:0042063 80 0.012
dendrite morphogenesis GO:0048813 199 0.012
indole containing compound biosynthetic process GO:0042435 4 0.012
olfactory behavior GO:0042048 97 0.012
formation of primary germ layer GO:0001704 24 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
chemical homeostasis GO:0048878 92 0.012
trachea development GO:0060438 29 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
peptidyl threonine modification GO:0018210 3 0.012
establishment of tissue polarity GO:0007164 87 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
response to inorganic substance GO:0010035 44 0.012
fatty acid metabolic process GO:0006631 20 0.012
dopamine biosynthetic process from tyrosine GO:0006585 1 0.012
lipid biosynthetic process GO:0008610 46 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
response to endogenous stimulus GO:0009719 119 0.011
purine containing compound metabolic process GO:0072521 155 0.011
eye morphogenesis GO:0048592 260 0.011
behavioral response to ethanol GO:0048149 49 0.011
regulation of cell proliferation GO:0042127 163 0.011

Spn28D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
disease of metabolism DOID:0014667 0 0.025
disease of cellular proliferation DOID:14566 0 0.023
carbohydrate metabolism disease DOID:0050013 0 0.022
acquired metabolic disease DOID:0060158 0 0.022
hypertension DOID:10763 0 0.021
artery disease DOID:0050828 0 0.021
vascular disease DOID:178 0 0.021
essential hypertension DOID:10825 0 0.021
cardiovascular system disease DOID:1287 0 0.021
diabetes mellitus DOID:9351 0 0.016
glucose metabolism disease DOID:4194 0 0.016
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011