Drosophila melanogaster

53 known processes

Trh (Dmel_CG9122)

Tryptophan hydroxylase

(Aliases: Dmel\CG9122,CG9122,DTRH,TRH,CT9937)

Trh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.998
male courtship behavior GO:0008049 63 0.944
Fly
g protein coupled receptor signaling pathway GO:0007186 136 0.890
response to ethanol GO:0045471 59 0.865
sensory perception GO:0007600 196 0.814
regulation of reproductive process GO:2000241 54 0.736
Worm
olfactory behavior GO:0042048 97 0.736
multi multicellular organism process GO:0044706 123 0.680
Worm Fly
tube morphogenesis GO:0035239 191 0.661
chemosensory behavior GO:0007635 106 0.616
positive regulation of behavior GO:0048520 19 0.594
gliogenesis GO:0042063 80 0.592
embryonic morphogenesis GO:0048598 206 0.557
response to organic substance GO:0010033 284 0.553
Worm
rhythmic process GO:0048511 106 0.543
open tracheal system development GO:0007424 204 0.521
Fly
negative regulation of cell communication GO:0010648 223 0.493
multi organism reproductive behavior GO:0044705 121 0.472
Worm Fly
multi organism behavior GO:0051705 175 0.463
Worm Fly
circadian rhythm GO:0007623 105 0.449
feeding behavior GO:0007631 50 0.436
Worm
negative regulation of signal transduction GO:0009968 206 0.397
male mating behavior GO:0060179 70 0.356
Fly
head development GO:0060322 135 0.351
immune response GO:0006955 246 0.347
axis specification GO:0009798 167 0.335
central nervous system development GO:0007417 201 0.334
negative regulation of signaling GO:0023057 219 0.334
behavioral response to ethanol GO:0048149 49 0.322
positive regulation of signal transduction GO:0009967 223 0.288
Worm
secretion by cell GO:0032940 101 0.271
tissue migration GO:0090130 155 0.266
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.261
adult behavior GO:0030534 137 0.257
Fly
regulation of tube architecture open tracheal system GO:0035152 68 0.257
brain development GO:0007420 120 0.252
response to endogenous stimulus GO:0009719 119 0.248
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.247
positive regulation of nucleic acid templated transcription GO:1903508 266 0.238
malpighian tubule morphogenesis GO:0007443 44 0.234
dendrite morphogenesis GO:0048813 199 0.224
negative regulation of rna metabolic process GO:0051253 251 0.222
enzyme linked receptor protein signaling pathway GO:0007167 179 0.220
Worm
regulation of tube size GO:0035150 46 0.216
regulation of cellular protein metabolic process GO:0032268 243 0.213
defense response GO:0006952 300 0.212
cell motility GO:0048870 251 0.210
Fly
hindgut morphogenesis GO:0007442 58 0.203
negative regulation of gene expression GO:0010629 387 0.201
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.200
phenol containing compound metabolic process GO:0018958 57 0.198
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.198
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.190
cell migration GO:0016477 238 0.187
Fly
positive regulation of biosynthetic process GO:0009891 316 0.187
positive regulation of rna metabolic process GO:0051254 271 0.183
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.182
respiratory system development GO:0060541 213 0.177
Fly
wnt signaling pathway GO:0016055 98 0.171
response to alcohol GO:0097305 95 0.169
regulation of tube length open tracheal system GO:0035159 24 0.166
regulation of phosphorus metabolic process GO:0051174 210 0.162
phosphorylation GO:0016310 294 0.154
negative regulation of transcription dna templated GO:0045892 237 0.154
regulation of epithelial cell proliferation GO:0050678 4 0.153
regulation of protein metabolic process GO:0051246 256 0.153
regulation of muscle organ development GO:0048634 13 0.148
regulation of response to nutrient levels GO:0032107 18 0.141
negative regulation of cell proliferation GO:0008285 69 0.141
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.135
sensory perception of chemical stimulus GO:0007606 116 0.131
regulation of behavior GO:0050795 75 0.131
positive regulation of response to stimulus GO:0048584 323 0.128
Worm
positive regulation of rna biosynthetic process GO:1902680 266 0.124
regulation of cell development GO:0060284 215 0.122
sensory perception of smell GO:0007608 80 0.120
negative regulation of response to stimulus GO:0048585 258 0.119
organophosphate metabolic process GO:0019637 195 0.115
larval feeding behavior GO:0030536 15 0.115
regulation of canonical wnt signaling pathway GO:0060828 15 0.114
peptidyl amino acid modification GO:0018193 105 0.113
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.112
regionalization GO:0003002 416 0.112
multicellular organismal aging GO:0010259 140 0.111
Worm
regulation of phosphate metabolic process GO:0019220 210 0.110
developmental maturation GO:0021700 172 0.109
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.107
single organismal cell cell adhesion GO:0016337 45 0.107
response to organonitrogen compound GO:0010243 75 0.105
cellular amino acid metabolic process GO:0006520 61 0.104
Worm
regulation of immune system process GO:0002682 176 0.102
response to other organism GO:0051707 293 0.102
cell junction assembly GO:0034329 42 0.102
positive regulation of macromolecule metabolic process GO:0010604 405 0.101
mesodermal cell fate specification GO:0007501 2 0.100
cellular response to organic substance GO:0071310 132 0.100
Worm
anterior posterior pattern specification GO:0009952 136 0.100
cellular amine metabolic process GO:0044106 12 0.097
Worm
embryonic hindgut morphogenesis GO:0048619 48 0.095
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.095
regulation of cell death GO:0010941 173 0.094
embryo development ending in birth or egg hatching GO:0009792 152 0.094
Worm
regulation of anatomical structure size GO:0090066 163 0.091
canonical wnt signaling pathway GO:0060070 21 0.089
cellular protein modification process GO:0006464 438 0.088
embryonic axis specification GO:0000578 107 0.087
localization of cell GO:0051674 257 0.086
Fly
digestive system development GO:0055123 149 0.086
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.085
digestive tract morphogenesis GO:0048546 127 0.085
dorsal trunk growth open tracheal system GO:0035001 7 0.085
protein modification process GO:0036211 438 0.084
molting cycle chitin based cuticle GO:0007591 56 0.084
Fly
regulation of protein kinase activity GO:0045859 51 0.083
regulation of cellular component movement GO:0051270 42 0.082
Fly
urogenital system development GO:0001655 72 0.082
regulation of immune response GO:0050776 118 0.080
regulation of locomotion GO:0040012 42 0.079
Fly
regulation of cell cell adhesion GO:0022407 21 0.079
regulation of localization GO:0032879 275 0.078
Fly
intracellular signal transduction GO:0035556 300 0.077
morphogenesis of an epithelium GO:0002009 276 0.077
regulation of defense response GO:0031347 102 0.074
negative regulation of epithelial cell proliferation GO:0050680 4 0.074
formation of primary germ layer GO:0001704 24 0.073
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.073
positive regulation of cell communication GO:0010647 250 0.073
Worm
single organism intracellular transport GO:1902582 207 0.073
intracellular receptor signaling pathway GO:0030522 19 0.073
negative regulation of cellular metabolic process GO:0031324 382 0.073
regulation of organelle organization GO:0033043 196 0.070
regulation of innate immune response GO:0045088 71 0.070
protein transport GO:0015031 155 0.066
innate immune response GO:0045087 144 0.066
epithelium migration GO:0090132 148 0.066
Fly
positive regulation of protein metabolic process GO:0051247 128 0.066
cell death GO:0008219 279 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.065
regulation of tube diameter open tracheal system GO:0035158 11 0.064
positive regulation of gene expression GO:0010628 290 0.064
death GO:0016265 284 0.064
forebrain development GO:0030900 2 0.063
regulation of cellular localization GO:0060341 136 0.062
protein catabolic process GO:0030163 101 0.062
regulation of multicellular organismal development GO:2000026 414 0.062
Fly
proteolysis GO:0006508 192 0.062
response to abiotic stimulus GO:0009628 341 0.061
Fly
positive regulation of cell proliferation GO:0008284 47 0.061
cellular response to chemical stimulus GO:0070887 199 0.061
Worm
establishment of localization in cell GO:0051649 402 0.061
segmentation GO:0035282 207 0.060
regulation of wnt signaling pathway GO:0030111 68 0.060
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.059
carbohydrate derivative biosynthetic process GO:1901137 85 0.058
positive regulation of multicellular organismal process GO:0051240 143 0.058
mating GO:0007618 120 0.058
Fly
regulation of cell proliferation GO:0042127 163 0.057
regulation of molecular function GO:0065009 217 0.057
extracellular matrix disassembly GO:0022617 4 0.057
negative regulation of phosphorus metabolic process GO:0010563 45 0.056
response to external biotic stimulus GO:0043207 293 0.056
cell maturation GO:0048469 144 0.055
tracheal outgrowth open tracheal system GO:0007426 18 0.055
taxis GO:0042330 304 0.055
Fly
spermatogenesis GO:0007283 200 0.053
male gamete generation GO:0048232 201 0.053
response to organic cyclic compound GO:0014070 89 0.052
larval behavior GO:0030537 42 0.052
negative regulation of cellular biosynthetic process GO:0031327 277 0.052
amine metabolic process GO:0009308 12 0.050
Worm
growth GO:0040007 359 0.050
response to oxygen containing compound GO:1901700 200 0.050
digestive tract development GO:0048565 149 0.049
positive regulation of signaling GO:0023056 243 0.049
Worm
organic substance catabolic process GO:1901575 308 0.049
regulation of intracellular signal transduction GO:1902531 236 0.049
embryonic pattern specification GO:0009880 174 0.048
macromolecule catabolic process GO:0009057 161 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.048
transcription from rna polymerase ii promoter GO:0006366 368 0.047
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.046
organic acid metabolic process GO:0006082 103 0.046
Worm
protein phosphorylation GO:0006468 169 0.046
response to lipid GO:0033993 38 0.046
locomotory behavior GO:0007626 176 0.045
Fly
cellular response to endogenous stimulus GO:0071495 80 0.045
Worm
regulation of phosphorylation GO:0042325 147 0.045
extracellular structure organization GO:0043062 46 0.044
neuroblast proliferation GO:0007405 74 0.044
positive regulation of growth GO:0045927 75 0.044
epithelial cell migration GO:0010631 148 0.042
Fly
developmental growth involved in morphogenesis GO:0060560 65 0.042
anterior posterior axis specification embryo GO:0008595 103 0.042
positive regulation of cell motility GO:2000147 3 0.042
regulation of response to external stimulus GO:0032101 115 0.041
renal tubule morphogenesis GO:0061333 44 0.041
organic substance transport GO:0071702 257 0.041
neurological system process GO:0050877 358 0.041
oxoacid metabolic process GO:0043436 103 0.041
Worm
appendage morphogenesis GO:0035107 397 0.040
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.040
Fly
mesoderm morphogenesis GO:0048332 22 0.040
mesoderm formation GO:0001707 21 0.039
positive regulation of developmental growth GO:0048639 62 0.039
imaginal disc derived appendage development GO:0048737 399 0.039
glial cell differentiation GO:0010001 35 0.038
regulation of cell differentiation GO:0045595 302 0.038
Mouse
synapse assembly GO:0007416 143 0.038
single organism cell adhesion GO:0098602 47 0.037
tripartite regional subdivision GO:0007351 103 0.037
regulation of tube size open tracheal system GO:0035151 43 0.037
negative regulation of apoptotic process GO:0043066 63 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.036
establishment or maintenance of cell polarity GO:0007163 167 0.036
negative regulation of multicellular organismal process GO:0051241 142 0.036
positive regulation of phosphorus metabolic process GO:0010562 139 0.036
epithelial cell migration open tracheal system GO:0007427 32 0.036
Fly
regulation of organ morphogenesis GO:2000027 78 0.036
cell cell junction assembly GO:0007043 38 0.035
regulation of growth GO:0040008 233 0.034
multicellular organismal reproductive behavior GO:0033057 110 0.034
Worm Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.034
regulation of transferase activity GO:0051338 58 0.034
extrinsic apoptotic signaling pathway GO:0097191 1 0.034
response to biotic stimulus GO:0009607 294 0.034
regulation of cellular component biogenesis GO:0044087 201 0.033
response to wounding GO:0009611 94 0.033
Fly
regulation of response to stress GO:0080134 200 0.032
glandular epithelial cell differentiation GO:0002067 1 0.032
multicellular organism growth GO:0035264 46 0.032
positive regulation of developmental process GO:0051094 143 0.032
Mouse
muscle organ development GO:0007517 127 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
regulation of protein modification process GO:0031399 112 0.032
cell migration involved in gastrulation GO:0042074 9 0.031
regulation of response to extracellular stimulus GO:0032104 18 0.031
cell cell junction organization GO:0045216 55 0.031
immune response regulating signaling pathway GO:0002764 2 0.031
catabolic process GO:0009056 409 0.031
response to drug GO:0042493 17 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
intracellular transport GO:0046907 228 0.030
cellular ketone metabolic process GO:0042180 24 0.030
positive regulation of immune response GO:0050778 63 0.030
branching involved in open tracheal system development GO:0060446 45 0.030
positive regulation of immune system process GO:0002684 68 0.030
cell proliferation GO:0008283 299 0.029
regulation of tube diameter GO:0035296 14 0.029
branching morphogenesis of an epithelial tube GO:0048754 45 0.028
neuroblast division GO:0055057 35 0.028
regulation of nucleocytoplasmic transport GO:0046822 35 0.028
negative regulation of cell death GO:0060548 81 0.027
organ growth GO:0035265 56 0.027
response to nitrogen compound GO:1901698 90 0.027
cell junction organization GO:0034330 57 0.027
regulation of catalytic activity GO:0050790 185 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
cell fate specification GO:0001708 71 0.026
cytoplasmic transport GO:0016482 130 0.026
programmed cell death GO:0012501 257 0.025
developmental growth GO:0048589 280 0.025
salivary gland development GO:0007431 162 0.025
regulation of programmed cell death GO:0043067 152 0.025
r7 cell differentiation GO:0045466 43 0.025
mitotic nuclear division GO:0007067 213 0.024
tube development GO:0035295 244 0.024
regulation of cell morphogenesis GO:0022604 163 0.024
positive regulation of defense response GO:0031349 59 0.024
telencephalon development GO:0021537 2 0.024
ribosomal large subunit biogenesis GO:0042273 1 0.024
blastoderm segmentation GO:0007350 159 0.023
adult locomotory behavior GO:0008344 76 0.023
Fly
negative regulation of protein metabolic process GO:0051248 85 0.023
regulation of protein transport GO:0051223 57 0.023
single organism carbohydrate metabolic process GO:0044723 72 0.023
establishment of protein localization GO:0045184 163 0.023
nucleocytoplasmic transport GO:0006913 72 0.023
wing disc morphogenesis GO:0007472 344 0.023
negative regulation of molecular function GO:0044092 51 0.022
foregut morphogenesis GO:0007440 10 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
intercellular transport GO:0010496 2 0.021
regulation of nervous system development GO:0051960 248 0.021
negative regulation of phosphate metabolic process GO:0045936 45 0.021
organic hydroxy compound biosynthetic process GO:1901617 21 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
regulation of protein localization GO:0032880 76 0.021
neuromuscular junction development GO:0007528 149 0.020
protein localization GO:0008104 284 0.020
cell division GO:0051301 248 0.020
sex differentiation GO:0007548 81 0.020
regulation of multi organism process GO:0043900 131 0.020
Worm
stem cell development GO:0048864 79 0.020
endoderm formation GO:0001706 3 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.020
regulation of phosphatase activity GO:0010921 3 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
single organism biosynthetic process GO:0044711 206 0.020
Worm
lateral inhibition GO:0046331 206 0.020
secondary branching open tracheal system GO:0007429 2 0.020
cranial nerve development GO:0021545 1 0.020
appendage development GO:0048736 401 0.020
regulation of embryonic development GO:0045995 68 0.019
regulation of cell cycle process GO:0010564 181 0.019
nucleotide metabolic process GO:0009117 161 0.019
compound eye morphogenesis GO:0001745 249 0.019
rhythmic behavior GO:0007622 76 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
negative regulation of intracellular signal transduction GO:1902532 57 0.019
stem cell maintenance GO:0019827 67 0.018
gland development GO:0048732 191 0.018
Mouse
positive regulation of phosphorylation GO:0042327 87 0.018
dendrite development GO:0016358 204 0.018
positive regulation of nervous system development GO:0051962 69 0.018
primary branching open tracheal system GO:0007428 6 0.018
neuromuscular process GO:0050905 21 0.018
detection of stimulus involved in sensory perception GO:0050906 92 0.018
anterior posterior axis specification GO:0009948 109 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
endocytosis GO:0006897 310 0.017
mesoderm development GO:0007498 78 0.017
negative regulation of cyclic nucleotide metabolic process GO:0030800 3 0.017
regulation of kinase activity GO:0043549 53 0.017
cellular response to hormone stimulus GO:0032870 44 0.017
regulation of hydrolase activity GO:0051336 97 0.017
tissue morphogenesis GO:0048729 297 0.017
defense response to bacterium GO:0042742 178 0.017
nuclear transport GO:0051169 72 0.017
renal tubule development GO:0061326 64 0.017
carbohydrate metabolic process GO:0005975 82 0.017
response to extracellular stimulus GO:0009991 116 0.017
negative regulation of cell cell adhesion GO:0022408 8 0.017
regulation of cell migration GO:0030334 22 0.017
Fly
maintenance of location GO:0051235 73 0.016
Worm
oocyte development GO:0048599 124 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
nitrogen compound transport GO:0071705 85 0.016
positive regulation of feeding behavior GO:2000253 8 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
response to nutrient levels GO:0031667 114 0.016
regulation of proteolysis GO:0030162 87 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
regulation of cell adhesion GO:0030155 27 0.016
internal peptidyl lysine acetylation GO:0018393 38 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
negative regulation of developmental process GO:0051093 201 0.016
apoptotic process GO:0006915 159 0.016
secretion GO:0046903 109 0.016
regulation of organ growth GO:0046620 42 0.015
single organism nuclear import GO:1902593 51 0.015
courtship behavior GO:0007619 68 0.015
Fly
glial cell migration GO:0008347 31 0.015
renal system development GO:0072001 72 0.015
imaginal disc growth GO:0007446 37 0.015
chromosome organization GO:0051276 360 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
mapk cascade GO:0000165 107 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
muscle system process GO:0003012 21 0.014
immune system process GO:0002376 347 0.014
hindgut development GO:0061525 58 0.014
mushroom body development GO:0016319 70 0.014
sensory organ morphogenesis GO:0090596 260 0.014
protein ubiquitination GO:0016567 70 0.014
phagocytosis GO:0006909 215 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
body morphogenesis GO:0010171 2 0.013
salivary gland histolysis GO:0035070 88 0.013
muscle structure development GO:0061061 224 0.013
positive regulation of multicellular organism growth GO:0040018 21 0.013
regulation of membrane depolarization GO:0003254 1 0.013
negative regulation of proteolysis GO:0045861 31 0.013
cellular response to decreased oxygen levels GO:0036294 30 0.013
branch fusion open tracheal system GO:0035147 17 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
cellular catabolic process GO:0044248 372 0.013
response to axon injury GO:0048678 12 0.013
camera type eye development GO:0043010 4 0.013
regulation of camp biosynthetic process GO:0030817 12 0.012
chitin based cuticle development GO:0040003 49 0.012
regulation of cell cycle GO:0051726 291 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
positive regulation of molecular function GO:0044093 136 0.012
positive regulation of transport GO:0051050 92 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
gland morphogenesis GO:0022612 145 0.012
smoothened signaling pathway GO:0007224 49 0.012
regulation of apoptotic process GO:0042981 130 0.012
stem cell division GO:0017145 69 0.012
reproductive system development GO:0061458 74 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
regulation of malpighian tubule diameter GO:0035297 3 0.012
circadian behavior GO:0048512 76 0.012
head involution GO:0008258 35 0.012
regulation of compound eye cone cell fate specification GO:0042682 4 0.012
memory GO:0007613 94 0.011
response to bacterium GO:0009617 198 0.011
epithelial cell proliferation GO:0050673 15 0.011
cellular protein catabolic process GO:0044257 83 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
positive regulation of protein modification process GO:0031401 58 0.011
endodermal cell differentiation GO:0035987 3 0.011
regulation of neuron death GO:1901214 26 0.011
reproductive behavior GO:0019098 122 0.011
Worm Fly
positive regulation of transcription dna templated GO:0045893 266 0.011
extracellular matrix organization GO:0030198 32 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
hindbrain development GO:0030902 2 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
instar larval development GO:0002168 55 0.011
regulation of transport GO:0051049 181 0.011
positive regulation of neurotransmitter transport GO:0051590 2 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
regulation of developmental growth GO:0048638 174 0.011
morphogenesis of a branching epithelium GO:0061138 45 0.010
long term memory GO:0007616 62 0.010
protein secretion GO:0009306 45 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
defense response to gram negative bacterium GO:0050829 94 0.010
cellular macromolecule localization GO:0070727 220 0.010

Trh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
bone development disease DOID:0080006 0 0.029
bone disease DOID:0080001 0 0.029
disease of anatomical entity DOID:7 0 0.029
musculoskeletal system disease DOID:17 0 0.029
connective tissue disease DOID:65 0 0.029