Drosophila melanogaster

82 known processes

snRNP-U1-70K (Dmel_CG8749)

small ribonucleoprotein particle U1 subunit 70K

(Aliases: U170K,snRNP70K,U1 70K snRNP,U1snRNP-70K,U1 70k,Dm70K,U1 snRNP,U1 70K,U1-70K,snRNP27D,dU1-70K,l(2)02107,70K,snRNP,CG8749,U1-70k,Dmel\CG8749)

snRNP-U1-70K biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna processing GO:0006397 104 0.581
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.432
rna splicing via transesterification reactions GO:0000375 73 0.390
regulation of meiosis GO:0040020 3 0.382
rna splicing GO:0008380 83 0.361
larval development GO:0002164 104 0.339
Worm
regulation of mrna splicing via spliceosome GO:0048024 64 0.241
developmental growth GO:0048589 280 0.231
rna processing GO:0006396 147 0.197
localization of cell GO:0051674 257 0.191
embryo development ending in birth or egg hatching GO:0009792 152 0.191
Worm
cytoskeleton dependent cytokinesis GO:0061640 81 0.176
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.153
regulation of growth GO:0040008 233 0.152
intracellular signal transduction GO:0035556 300 0.146
regulation of cellular component biogenesis GO:0044087 201 0.145
positive regulation of gene expression GO:0010628 290 0.144
Mouse
positive regulation of signaling GO:0023056 243 0.143
regulation of cell cycle process GO:0010564 181 0.137
mrna splicing via spliceosome GO:0000398 73 0.125
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.124
body morphogenesis GO:0010171 2 0.117
negative regulation of cellular metabolic process GO:0031324 382 0.114
multicellular organism growth GO:0035264 46 0.112
cell death GO:0008219 279 0.110
protein localization GO:0008104 284 0.109
nuclear division GO:0000280 332 0.107
positive regulation of response to stimulus GO:0048584 323 0.106
negative regulation of rna metabolic process GO:0051253 251 0.105
regulation of developmental growth GO:0048638 174 0.105
organelle fission GO:0048285 340 0.099
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.095
mitotic g2 m transition checkpoint GO:0044818 70 0.094
regulation of rna splicing GO:0043484 69 0.093
photoreceptor cell differentiation GO:0046530 170 0.093
reproductive system development GO:0061458 74 0.091
Worm
positive regulation of cell communication GO:0010647 250 0.087
endocytosis GO:0006897 310 0.086
protein complex biogenesis GO:0070271 201 0.085
mitotic nuclear division GO:0007067 213 0.084
development of primary sexual characteristics GO:0045137 50 0.082
Worm
cell division GO:0051301 248 0.081
determination of adult lifespan GO:0008340 137 0.081
alternative mrna splicing via spliceosome GO:0000380 60 0.079
cell migration GO:0016477 238 0.077
mitotic cell cycle phase transition GO:0044772 138 0.077
growth GO:0040007 359 0.077
positive regulation of rna metabolic process GO:0051254 271 0.075
Mouse
dephosphorylation GO:0016311 51 0.073
regulation of phosphate metabolic process GO:0019220 210 0.071
positive regulation of signal transduction GO:0009967 223 0.067
regulation of intracellular signal transduction GO:1902531 236 0.065
immune system process GO:0002376 347 0.064
death GO:0016265 284 0.062
aging GO:0007568 143 0.061
mrna metabolic process GO:0016071 124 0.061
positive regulation of intracellular signal transduction GO:1902533 116 0.060
mitotic cytokinesis GO:0000281 50 0.060
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.060
regulation of mrna processing GO:0050684 71 0.058
regulation of protein complex disassembly GO:0043244 29 0.056
protein modification process GO:0036211 438 0.054
phosphorylation GO:0016310 294 0.053
mitotic spindle organization GO:0007052 220 0.053
regulation of phosphorus metabolic process GO:0051174 210 0.053
posttranscriptional regulation of gene expression GO:0010608 145 0.053
actin filament based process GO:0030029 220 0.052
negative regulation of cellular component organization GO:0051129 108 0.052
regulation of phosphorylation GO:0042325 147 0.048
histone h2a acetylation GO:0043968 1 0.048
regulation of cell cycle GO:0051726 291 0.047
regulation of mrna metabolic process GO:1903311 72 0.047
embryonic morphogenesis GO:0048598 206 0.047
regulation of multicellular organismal development GO:2000026 414 0.047
negative regulation of developmental process GO:0051093 201 0.046
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
cellular response to dna damage stimulus GO:0006974 223 0.046
cell cycle g1 s phase transition GO:0044843 31 0.045
positive regulation of transcription dna templated GO:0045893 266 0.045
sex differentiation GO:0007548 81 0.044
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.044
establishment of organelle localization GO:0051656 122 0.044
modification dependent macromolecule catabolic process GO:0043632 79 0.042
cell cycle phase transition GO:0044770 140 0.042
macromolecule catabolic process GO:0009057 161 0.041
vesicle mediated transport GO:0016192 381 0.041
dna templated transcription elongation GO:0006354 18 0.041
regulation of cell division GO:0051302 72 0.040
molting cycle GO:0042303 56 0.040
positive regulation of rna biosynthetic process GO:1902680 266 0.040
spindle organization GO:0007051 253 0.039
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.039
nucleosome organization GO:0034728 59 0.039
multi multicellular organism process GO:0044706 123 0.039
cellular protein localization GO:0034613 160 0.039
regulation of protein transport GO:0051223 57 0.039
multi organism reproductive behavior GO:0044705 121 0.038
axon development GO:0061564 297 0.038
regulation of nuclear division GO:0051783 58 0.038
regulation of molecular function GO:0065009 217 0.038
multicellular organismal reproductive behavior GO:0033057 110 0.038
positive regulation of developmental process GO:0051094 143 0.038
cellular component assembly involved in morphogenesis GO:0010927 151 0.038
negative regulation of response to stimulus GO:0048585 258 0.037
protein complex assembly GO:0006461 200 0.037
striated muscle myosin thick filament assembly GO:0071688 3 0.037
mrna catabolic process GO:0006402 33 0.036
protein transport GO:0015031 155 0.036
organic substance catabolic process GO:1901575 308 0.036
regulation of multi organism process GO:0043900 131 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
transcription from rna polymerase ii promoter GO:0006366 368 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
muscle structure development GO:0061061 224 0.035
regulation of meiotic cell cycle GO:0051445 9 0.035
snrna processing GO:0016180 14 0.034
posttranscriptional gene silencing by rna GO:0035194 45 0.034
positive regulation of cellular component biogenesis GO:0044089 80 0.034
negative regulation of cell cycle process GO:0010948 109 0.034
programmed cell death GO:0012501 257 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.033
compound eye photoreceptor cell differentiation GO:0001751 140 0.033
cellular protein complex assembly GO:0043623 71 0.033
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.033
sister chromatid segregation GO:0000819 92 0.033
regulation of cell death GO:0010941 173 0.033
morphogenesis of an epithelium GO:0002009 276 0.033
digestive system development GO:0055123 149 0.031
cell motility GO:0048870 251 0.031
muscle cell development GO:0055001 50 0.031
rna catabolic process GO:0006401 37 0.031
protein ubiquitination GO:0016567 70 0.030
mrna splice site selection GO:0006376 1 0.030
regulation of translation GO:0006417 56 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.029
rna 3 end processing GO:0031123 45 0.029
tissue morphogenesis GO:0048729 297 0.029
regulation of cell differentiation GO:0045595 302 0.028
regulation of cellular localization GO:0060341 136 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
spindle assembly GO:0051225 80 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
ncrna metabolic process GO:0034660 43 0.027
regulation of transport GO:0051049 181 0.026
macromolecular complex assembly GO:0065003 256 0.026
eye development GO:0001654 323 0.026
camera type eye development GO:0043010 4 0.026
establishment of localization in cell GO:0051649 402 0.025
muscle cell differentiation GO:0042692 103 0.025
eye photoreceptor cell differentiation GO:0001754 145 0.025
positive regulation of developmental growth GO:0048639 62 0.024
hematopoietic or lymphoid organ development GO:0048534 57 0.024
cell growth GO:0016049 108 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
regulation of apoptotic process GO:0042981 130 0.024
multi organism behavior GO:0051705 175 0.024
appendage development GO:0048736 401 0.024
genitalia development GO:0048806 26 0.024
Worm
cellular catabolic process GO:0044248 372 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
Mouse
regulation of neurogenesis GO:0050767 158 0.023
photoreceptor cell development GO:0042461 96 0.023
regulation of dna templated transcription elongation GO:0032784 17 0.023
rna localization GO:0006403 115 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
positive regulation of growth GO:0045927 75 0.023
regulation of protein localization GO:0032880 76 0.023
regulation of intracellular protein transport GO:0033157 46 0.023
regulation of behavior GO:0050795 75 0.023
regulation of cell proliferation GO:0042127 163 0.023
imaginal disc derived appendage development GO:0048737 399 0.022
rhabdomere development GO:0042052 38 0.022
compound eye development GO:0048749 307 0.022
tripartite regional subdivision GO:0007351 103 0.022
reproductive structure development GO:0048608 74 0.022
Worm
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
dendrite morphogenesis GO:0048813 199 0.021
negative regulation of meiotic cell cycle GO:0051447 2 0.021
homeostatic process GO:0042592 199 0.021
mapk cascade GO:0000165 107 0.021
aromatic compound catabolic process GO:0019439 166 0.021
axonogenesis GO:0007409 290 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
negative regulation of organelle organization GO:0010639 56 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
regulation of synapse organization GO:0050807 110 0.021
appendage morphogenesis GO:0035107 397 0.020
catabolic process GO:0009056 409 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
positive regulation of multicellular organism growth GO:0040018 21 0.020
actin cytoskeleton organization GO:0030036 206 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
mrna transport GO:0051028 15 0.020
regulation of intracellular transport GO:0032386 64 0.020
organic substance transport GO:0071702 257 0.019
mitotic sister chromatid segregation GO:0000070 87 0.019
ras protein signal transduction GO:0007265 88 0.019
epithelial cell differentiation GO:0030855 322 0.019
negative regulation of cell cycle GO:0045786 116 0.019
phagocytosis GO:0006909 215 0.019
cell proliferation GO:0008283 299 0.019
chromosome segregation GO:0007059 157 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
spliceosomal complex assembly GO:0000245 1 0.019
tube morphogenesis GO:0035239 191 0.019
dna integrity checkpoint GO:0031570 81 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of neuron projection development GO:0010975 69 0.019
gland development GO:0048732 191 0.019
regulation of localization GO:0032879 275 0.019
positive regulation of biosynthetic process GO:0009891 316 0.018
apoptotic process GO:0006915 159 0.018
nuclear transport GO:0051169 72 0.018
cellular protein complex disassembly GO:0043624 35 0.018
centrosome organization GO:0051297 163 0.018
meiotic nuclear division GO:0007126 151 0.018
regulation of nervous system development GO:0051960 248 0.018
gene silencing by rna GO:0031047 57 0.018
reproductive behavior GO:0019098 122 0.018
regulation of neuron differentiation GO:0045664 103 0.018
snrna metabolic process GO:0016073 14 0.018
regulation of organelle organization GO:0033043 196 0.017
gonad development GO:0008406 50 0.017
Worm
regulation of mapk cascade GO:0043408 92 0.017
regulation of protein complex assembly GO:0043254 42 0.017
regulation of response to stress GO:0080134 200 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
myofibril assembly GO:0030239 36 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.017
negative regulation of signal transduction GO:0009968 206 0.017
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
organelle localization GO:0051640 148 0.017
striated muscle cell development GO:0055002 50 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
positive regulation of intracellular transport GO:0032388 42 0.016
posttranscriptional gene silencing GO:0016441 46 0.016
cuticle pattern formation GO:0035017 27 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.016
regulation of proteasomal protein catabolic process GO:0061136 39 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
positive regulation of transport GO:0051050 92 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
negative regulation of gene expression GO:0010629 387 0.015
cellular component disassembly GO:0022411 46 0.015
single organism catabolic process GO:0044712 228 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
g1 s transition of mitotic cell cycle GO:0000082 31 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.015
striated muscle cell differentiation GO:0051146 90 0.015
dendrite development GO:0016358 204 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
dendrite guidance GO:0070983 21 0.014
intracellular transport GO:0046907 228 0.014
retina development in camera type eye GO:0060041 4 0.014
meiotic cell cycle GO:0051321 171 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
multicellular organismal aging GO:0010259 140 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
muscle system process GO:0003012 21 0.014
mrna cis splicing via spliceosome GO:0045292 1 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
notch signaling pathway GO:0007219 120 0.014
positive regulation of cell death GO:0010942 69 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
negative regulation of signaling GO:0023057 219 0.013
protein catabolic process GO:0030163 101 0.013
axis specification GO:0009798 167 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
spindle assembly involved in mitosis GO:0090307 50 0.013
cytokinesis GO:0000910 90 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
organophosphate metabolic process GO:0019637 195 0.013
rna polyadenylation GO:0043631 12 0.013
protein localization to nucleus GO:0034504 55 0.013
establishment of spindle localization GO:0051293 22 0.013
compound eye morphogenesis GO:0001745 249 0.013
regulation of erk1 and erk2 cascade GO:0070372 39 0.013
developmental maturation GO:0021700 172 0.012
heterochromatin organization GO:0070828 25 0.012
regulation of catalytic activity GO:0050790 185 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
Mouse
regulation of programmed cell death GO:0043067 152 0.012
eye photoreceptor cell development GO:0042462 81 0.012
dna metabolic process GO:0006259 227 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
negative regulation of cell communication GO:0010648 223 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
anatomical structure homeostasis GO:0060249 97 0.012
microtubule organizing center organization GO:0031023 168 0.012
negative regulation of growth GO:0045926 84 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
mrna 3 end processing GO:0031124 28 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
peptidyl amino acid modification GO:0018193 105 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
protein maturation GO:0051604 71 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
cellular macromolecule localization GO:0070727 220 0.011
histone exchange GO:0043486 21 0.011
regulation of cellular response to stress GO:0080135 89 0.011
secretion by cell GO:0032940 101 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.011
cardiovascular system development GO:0072358 82 0.011
positive regulation of protein import into nucleus GO:0042307 21 0.011
regulation of protein catabolic process GO:0042176 55 0.011
macromolecular complex disassembly GO:0032984 37 0.011
protein complex disassembly GO:0043241 36 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
heterocycle catabolic process GO:0046700 166 0.011
cellular protein modification process GO:0006464 438 0.011
mrna polyadenylation GO:0006378 11 0.011
immune system development GO:0002520 57 0.011
microtubule polymerization or depolymerization GO:0031109 39 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
positive regulation of molecular function GO:0044093 136 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of protein metabolic process GO:0051246 256 0.011
cellular amine metabolic process GO:0044106 12 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
regulation of wnt signaling pathway GO:0030111 68 0.010
telencephalon development GO:0021537 2 0.010
negative regulation of cytoskeleton organization GO:0051494 30 0.010
amine metabolic process GO:0009308 12 0.010
somatic muscle development GO:0007525 66 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
nucleotide catabolic process GO:0009166 109 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
mitotic cell cycle checkpoint GO:0007093 88 0.010

snRNP-U1-70K disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025