Drosophila melanogaster

150 known processes

PGRP-LC (Dmel_CG4432)

Peptidoglycan recognition protein LC

(Aliases: tot,PGRPLC,Pgrp-LC,PGRP-LCa,(PGRP)-LC,ird7,PGRP-LCx,Dmel\CG4432,Dm PGRP-LC,CG4432)

PGRP-LC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 1.000
Fly
melanization defense response GO:0035006 45 1.000
antibacterial humoral response GO:0019731 44 1.000
melanin metabolic process GO:0006582 47 1.000
pigment metabolic process GO:0042440 84 1.000
phenol containing compound metabolic process GO:0018958 57 1.000
innate immune response GO:0045087 144 1.000
immune response GO:0006955 246 1.000
regulation of melanization defense response GO:0035007 6 1.000
secondary metabolic process GO:0019748 75 1.000
positive regulation of antibacterial peptide production GO:0002803 20 1.000
immune system process GO:0002376 347 0.999
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.999
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.999
defense response GO:0006952 300 0.999
defense response to other organism GO:0098542 225 0.999
humoral immune response GO:0006959 117 0.999
antimicrobial peptide production GO:0002775 46 0.999
positive regulation of antimicrobial peptide production GO:0002225 28 0.999
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.999
Fly
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.998
antibacterial peptide production GO:0002778 22 0.998
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.998
Fly
regulation of secondary metabolic process GO:0043455 7 0.998
antibacterial peptide biosynthetic process GO:0002780 22 0.998
defense response to gram positive bacterium GO:0050830 41 0.998
Fly
glycosaminoglycan catabolic process GO:0006027 3 0.998
Fly
positive regulation of humoral immune response GO:0002922 28 0.998
regulation of defense response to bacterium GO:1900424 30 0.997
positive regulation of antimicrobial humoral response GO:0002760 28 0.997
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.997
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.997
Fly
melanotic encapsulation of foreign target GO:0035011 30 0.996
activation of innate immune response GO:0002218 4 0.996
positive regulation of immune effector process GO:0002699 28 0.996
regulation of humoral immune response GO:0002920 51 0.995
positive regulation of response to biotic stimulus GO:0002833 31 0.995
immune effector process GO:0002252 98 0.995
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.993
regulation of antibacterial peptide production GO:0002786 22 0.993
defense response to fungus GO:0050832 48 0.992
positive regulation of cellular amide metabolic process GO:0034250 26 0.991
positive regulation of defense response to bacterium GO:1900426 23 0.988
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.988
positive regulation of response to external stimulus GO:0032103 44 0.987
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.983
response to bacterium GO:0009617 198 0.982
response to peptidoglycan GO:0032494 2 0.982
Fly
regulation of defense response GO:0031347 102 0.982
amide biosynthetic process GO:0043604 42 0.981
antimicrobial humoral response GO:0019730 99 0.978
innate immune response activating signal transduction GO:0002758 2 0.969
organic hydroxy compound metabolic process GO:1901615 83 0.968
defense response to gram negative bacterium GO:0050829 94 0.967
response to external biotic stimulus GO:0043207 293 0.966
regulation of production of molecular mediator of immune response GO:0002700 44 0.962
defense response to bacterium GO:0042742 178 0.960
positive regulation of immune response GO:0050778 63 0.958
response to other organism GO:0051707 293 0.958
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.949
regulation of antimicrobial humoral response GO:0002759 50 0.948
regulation of cellular amide metabolic process GO:0034248 39 0.944
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.942
peptidoglycan catabolic process GO:0009253 3 0.940
Fly
positive regulation of multi organism process GO:0043902 40 0.939
regulation of innate immune response GO:0045088 71 0.934
peptide metabolic process GO:0006518 80 0.930
response to fungus GO:0009620 50 0.906
pattern recognition receptor signaling pathway GO:0002221 2 0.902
production of molecular mediator of immune response GO:0002440 46 0.896
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.894
Fly
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.890
antifungal humoral response GO:0019732 12 0.869
response to biotic stimulus GO:0009607 294 0.865
antimicrobial peptide biosynthetic process GO:0002777 38 0.863
regulation of immune response GO:0050776 118 0.850
regulation of response to external stimulus GO:0032101 115 0.843
regulation of multi organism process GO:0043900 131 0.840
regulation of antimicrobial peptide production GO:0002784 44 0.803
positive regulation of immune system process GO:0002684 68 0.802
organonitrogen compound biosynthetic process GO:1901566 117 0.795
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.793
regulation of response to stress GO:0080134 200 0.792
regulation of response to biotic stimulus GO:0002831 63 0.784
cellular amide metabolic process GO:0043603 80 0.778
negative regulation of defense response GO:0031348 35 0.776
Fly
positive regulation of defense response GO:0031349 59 0.738
defense response to virus GO:0051607 23 0.732
negative regulation of defense response to bacterium GO:1900425 7 0.729
Fly
regulation of immune effector process GO:0002697 52 0.715
positive regulation of biosynthetic process GO:0009891 316 0.686
regulation of immune system process GO:0002682 176 0.684
hemolymph coagulation GO:0042381 10 0.659
peptide biosynthetic process GO:0043043 42 0.639
encapsulation of foreign target GO:0035010 38 0.625
regulation of defense response to virus by host GO:0050691 10 0.618
positive regulation of melanization defense response GO:0035008 1 0.613
immune response regulating signaling pathway GO:0002764 2 0.598
positive regulation of response to stimulus GO:0048584 323 0.596
stress activated mapk cascade GO:0051403 52 0.565
Fly
organonitrogen compound metabolic process GO:1901564 318 0.526
negative regulation of cellular metabolic process GO:0031324 382 0.502
Fly
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.477
positive regulation of antifungal peptide production GO:0002804 6 0.472
cellular response to lipopolysaccharide GO:0071222 3 0.469
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.455
regulation of defense response to fungus GO:1900150 6 0.396
regulation of antifungal peptide production GO:0002788 6 0.391
negative regulation of signaling GO:0023057 219 0.384
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.381
response to wounding GO:0009611 94 0.369
antifungal peptide production GO:0002781 7 0.342
response to virus GO:0009615 28 0.339
positive regulation of defense response to virus by host GO:0002230 10 0.335
positive regulation of cellular biosynthetic process GO:0031328 316 0.306
vesicle mediated transport GO:0016192 381 0.299
positive regulation of innate immune response GO:0045089 38 0.298
regionalization GO:0003002 416 0.292
endocytosis GO:0006897 310 0.269
antifungal peptide biosynthetic process GO:0002783 5 0.260
zymogen activation GO:0031638 20 0.252
negative regulation of innate immune response GO:0045824 30 0.241
Fly
axis specification GO:0009798 167 0.239
jnk cascade GO:0007254 50 0.237
Fly
negative regulation of cell communication GO:0010648 223 0.208
Fly
immune response activating signal transduction GO:0002757 2 0.200
negative regulation of response to stimulus GO:0048585 258 0.198
Fly
phagocytosis GO:0006909 215 0.189
negative regulation of immune system process GO:0002683 50 0.182
Fly
wound healing GO:0042060 75 0.176
carbohydrate derivative metabolic process GO:1901135 217 0.171
Fly
positive regulation of signal transduction GO:0009967 223 0.167
regulation of mapk cascade GO:0043408 92 0.161
Fly
response to molecule of bacterial origin GO:0002237 7 0.160
rhythmic process GO:0048511 106 0.159
ommochrome metabolic process GO:0046152 19 0.152
dorsal ventral axis specification GO:0009950 66 0.151
proteolysis GO:0006508 192 0.150
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.146
Fly
stress activated protein kinase signaling cascade GO:0031098 55 0.137
Fly
negative regulation of intracellular signal transduction GO:1902532 57 0.136
Fly
regulation of intracellular signal transduction GO:1902531 236 0.127
Fly
response to lipopolysaccharide GO:0032496 4 0.124
appendage morphogenesis GO:0035107 397 0.122
signal transduction by phosphorylation GO:0023014 107 0.117
Fly
protein maturation GO:0051604 71 0.116
epithelial cell development GO:0002064 274 0.111
intracellular signal transduction GO:0035556 300 0.108
Fly
negative regulation of immune response GO:0050777 39 0.108
Fly
negative regulation of signal transduction GO:0009968 206 0.107
Fly
regulation of cellular response to stress GO:0080135 89 0.104
Fly
regulation of phosphate metabolic process GO:0019220 210 0.099
Fly
peptidoglycan metabolic process GO:0000270 3 0.098
Fly
phosphorylation GO:0016310 294 0.092
Fly
blastoderm segmentation GO:0007350 159 0.090
post embryonic appendage morphogenesis GO:0035120 385 0.089
regulation of stress activated mapk cascade GO:0032872 41 0.089
Fly
toll signaling pathway GO:0008063 25 0.084
circadian behavior GO:0048512 76 0.082
activation of immune response GO:0002253 5 0.081
small molecule metabolic process GO:0044281 305 0.079
regulation of phosphorylation GO:0042325 147 0.078
Fly
cellular response to organic substance GO:0071310 132 0.077
response to radiation GO:0009314 155 0.074
organic substance catabolic process GO:1901575 308 0.073
Fly
cellular response to chemical stimulus GO:0070887 199 0.072
negative regulation of rna biosynthetic process GO:1902679 240 0.071
protein modification process GO:0036211 438 0.071
regulation of anatomical structure size GO:0090066 163 0.069
l amino acid import GO:0043092 2 0.068
regulation of phosphorus metabolic process GO:0051174 210 0.068
Fly
small rna loading onto risc GO:0070922 6 0.066
dorsal ventral pattern formation GO:0009953 133 0.066
protein processing GO:0016485 68 0.066
response to endogenous stimulus GO:0009719 119 0.063
Fly
establishment of localization in cell GO:0051649 402 0.061
cellular response to lipid GO:0071396 20 0.061
negative regulation of gene expression GO:0010629 387 0.061
gene silencing GO:0016458 138 0.060
macromolecule catabolic process GO:0009057 161 0.060
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.058
positive regulation of cell communication GO:0010647 250 0.058
mucosal immune response GO:0002385 10 0.056
ion transmembrane transport GO:0034220 122 0.056
single organism behavior GO:0044708 391 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.054
regulation of protein metabolic process GO:0051246 256 0.054
response to monosaccharide GO:0034284 4 0.053
response to hexose GO:0009746 3 0.053
death GO:0016265 284 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.052
cellular response to abiotic stimulus GO:0071214 58 0.052
positive regulation of endopeptidase activity GO:0010950 26 0.051
ameboidal type cell migration GO:0001667 151 0.050
positive regulation of hydrolase activity GO:0051345 78 0.050
monovalent inorganic cation transport GO:0015672 40 0.050
regulation of molecular function GO:0065009 217 0.049
cation transmembrane transport GO:0098655 88 0.049
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.048
Fly
neural retina development GO:0003407 4 0.046
macromolecular complex assembly GO:0065003 256 0.046
regulation of jnk cascade GO:0046328 40 0.045
Fly
cellular protein modification process GO:0006464 438 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.044
cell death GO:0008219 279 0.043
positive regulation of intracellular signal transduction GO:1902533 116 0.043
homeostatic process GO:0042592 199 0.043
organophosphate metabolic process GO:0019637 195 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
negative regulation of mapk cascade GO:0043409 23 0.042
Fly
negative regulation of phosphorylation GO:0042326 35 0.042
Fly
retina development in camera type eye GO:0060041 4 0.042
positive regulation of protein metabolic process GO:0051247 128 0.042
cellular response to dna damage stimulus GO:0006974 223 0.041
response to oxygen containing compound GO:1901700 200 0.041
purine nucleotide catabolic process GO:0006195 109 0.040
negative regulation of response to external stimulus GO:0032102 22 0.039
Fly
regulation of protein localization GO:0032880 76 0.039
single organism catabolic process GO:0044712 228 0.039
segmentation GO:0035282 207 0.039
purine nucleoside metabolic process GO:0042278 127 0.038
regulation of body fluid levels GO:0050878 14 0.038
regulation of transport GO:0051049 181 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.038
embryonic pattern specification GO:0009880 174 0.037
oocyte development GO:0048599 124 0.037
cellular response to oxygen containing compound GO:1901701 79 0.036
catabolic process GO:0009056 409 0.036
Fly
negative regulation of response to biotic stimulus GO:0002832 12 0.036
Fly
regulation of cell cycle GO:0051726 291 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.036
response to organic substance GO:0010033 284 0.036
positive regulation of signaling GO:0023056 243 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.035
regulation of cell death GO:0010941 173 0.035
amino acid transport GO:0006865 12 0.035
wing disc morphogenesis GO:0007472 344 0.035
developmental maturation GO:0021700 172 0.035
positive regulation of protein transport GO:0051222 37 0.034
negative regulation of transcription dna templated GO:0045892 237 0.034
regulation of growth GO:0040008 233 0.034
organonitrogen compound catabolic process GO:1901565 128 0.034
Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.033
regulation of defense response to virus GO:0050688 14 0.033
regulation of toll signaling pathway GO:0008592 17 0.033
ion transport GO:0006811 145 0.033
cation transport GO:0006812 110 0.033
negative regulation of phosphorus metabolic process GO:0010563 45 0.033
Fly
response to nitrogen compound GO:1901698 90 0.033
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
carbohydrate metabolic process GO:0005975 82 0.033
response to oxygen radical GO:0000305 3 0.032
choline metabolic process GO:0019695 1 0.032
respiratory system development GO:0060541 213 0.032
actin filament based process GO:0030029 220 0.031
chemotaxis GO:0006935 249 0.031
cellular catabolic process GO:0044248 372 0.031
response to abiotic stimulus GO:0009628 341 0.031
appendage development GO:0048736 401 0.031
actin filament organization GO:0007015 126 0.031
determination of adult lifespan GO:0008340 137 0.031
Fly
embryonic morphogenesis GO:0048598 206 0.030
production of small rna involved in gene silencing by rna GO:0070918 15 0.030
guanosine containing compound metabolic process GO:1901068 74 0.030
guanosine containing compound catabolic process GO:1901069 74 0.030
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.030
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
negative regulation of phosphate metabolic process GO:0045936 45 0.030
Fly
positive regulation of transcription dna templated GO:0045893 266 0.030
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.030
regulation of cellular localization GO:0060341 136 0.030
organelle fission GO:0048285 340 0.029
open tracheal system development GO:0007424 204 0.029
neurological system process GO:0050877 358 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.029
regulation of response to wounding GO:1903034 19 0.029
aminoglycan catabolic process GO:0006026 6 0.028
Fly
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.028
protein complex biogenesis GO:0070271 201 0.028
mapk cascade GO:0000165 107 0.028
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.028
regulation of proteolysis GO:0030162 87 0.028
camera type eye development GO:0043010 4 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
multicellular organismal aging GO:0010259 140 0.027
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
peripheral nervous system development GO:0007422 52 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
programmed cell death GO:0012501 257 0.026
protein localization to nucleus GO:0034504 55 0.026
positive regulation of molecular function GO:0044093 136 0.026
cellular response to biotic stimulus GO:0071216 4 0.026
regulation of smoothened signaling pathway GO:0008589 28 0.026
single organism cellular localization GO:1902580 180 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.026
organ or tissue specific immune response GO:0002251 10 0.025
dna integrity checkpoint GO:0031570 81 0.025
activation of cysteine type endopeptidase activity GO:0097202 17 0.025
negative regulation of multi organism process GO:0043901 29 0.025
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
negative regulation of cell cycle phase transition GO:1901988 103 0.024
salivary gland development GO:0007431 162 0.024
developmental growth involved in morphogenesis GO:0060560 65 0.024
cytoplasm organization GO:0007028 64 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.024
protein localization GO:0008104 284 0.024
regulation of localization GO:0032879 275 0.024
regulation of tube architecture open tracheal system GO:0035152 68 0.024
mitotic spindle organization GO:0007052 220 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
cell cycle checkpoint GO:0000075 95 0.023
oocyte construction GO:0007308 112 0.023
gene silencing by rna GO:0031047 57 0.023
ribonucleoside metabolic process GO:0009119 127 0.023
nuclear division GO:0000280 332 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
molting cycle chitin based cuticle GO:0007591 56 0.023
regulation of gene silencing GO:0060968 63 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
aromatic compound catabolic process GO:0019439 166 0.022
purine nucleoside catabolic process GO:0006152 112 0.022
embryonic ectodermal digestive tract development GO:0048611 4 0.022
myotube cell development GO:0014904 3 0.022
neuroblast proliferation GO:0007405 74 0.022
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.022
organic substance transport GO:0071702 257 0.022
membrane organization GO:0061024 112 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
response to glucose GO:0009749 2 0.021
positive regulation of protein import into nucleus GO:0042307 21 0.021
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.021
protein complex assembly GO:0006461 200 0.021
regulation of cell cycle process GO:0010564 181 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
cellular protein localization GO:0034613 160 0.021
compound eye development GO:0048749 307 0.021
nuclear dna replication GO:0033260 1 0.021
tissue morphogenesis GO:0048729 297 0.020
apoptotic process GO:0006915 159 0.020
larval development GO:0002164 104 0.020
purine containing compound catabolic process GO:0072523 112 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
nucleoside catabolic process GO:0009164 112 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
aging GO:0007568 143 0.020
Fly
cuticle development GO:0042335 86 0.020
regulation of catabolic process GO:0009894 170 0.020
extrinsic apoptotic signaling pathway GO:0097191 1 0.020
cell migration GO:0016477 238 0.020
single organism carbohydrate metabolic process GO:0044723 72 0.019
circadian sleep wake cycle sleep GO:0050802 23 0.019
regulation of establishment of protein localization GO:0070201 61 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
response to lipid GO:0033993 38 0.019
response to organophosphorus GO:0046683 2 0.019
protein phosphorylation GO:0006468 169 0.019
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.019
cellular macromolecule localization GO:0070727 220 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
ribonucleoside catabolic process GO:0042454 112 0.019
chromatin silencing GO:0006342 76 0.019
positive regulation of protein localization to nucleus GO:1900182 21 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
purine ribonucleotide catabolic process GO:0009154 109 0.019
cellular response to mechanical stimulus GO:0071260 2 0.019
negative regulation of gene expression epigenetic GO:0045814 77 0.018
anterior posterior axis specification embryo GO:0008595 103 0.018
circadian rhythm GO:0007623 105 0.018
smoothened signaling pathway GO:0007224 49 0.018
sleep GO:0030431 49 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
hyperosmotic response GO:0006972 1 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
regulation of endopeptidase activity GO:0052548 36 0.018
digestive system development GO:0055123 149 0.018
skeletal muscle fiber development GO:0048741 3 0.018
dna metabolic process GO:0006259 227 0.018
autophagic cell death GO:0048102 83 0.018
regulation of synapse organization GO:0050807 110 0.018
acetylcholine catabolic process GO:0006581 1 0.018
response to superoxide GO:0000303 3 0.018
oocyte differentiation GO:0009994 145 0.018
signal transduction in response to dna damage GO:0042770 3 0.018
body morphogenesis GO:0010171 2 0.018
wnt signaling pathway GO:0016055 98 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
tissue homeostasis GO:0001894 36 0.017
regulation of catalytic activity GO:0050790 185 0.017
female meiotic division GO:0007143 70 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
nucleoside triphosphate catabolic process GO:0009143 108 0.017
gtp metabolic process GO:0046039 72 0.017
response to light stimulus GO:0009416 124 0.017
nucleocytoplasmic transport GO:0006913 72 0.017
positive regulation of proteolysis GO:0045862 52 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
ncrna metabolic process GO:0034660 43 0.017
sensory organ morphogenesis GO:0090596 260 0.017
nucleoside metabolic process GO:0009116 127 0.017
secretion by cell GO:0032940 101 0.017
anatomical structure homeostasis GO:0060249 97 0.017
dendrite morphogenesis GO:0048813 199 0.017
regulation of circadian rhythm GO:0042752 49 0.017
l amino acid transport GO:0015807 8 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
regulation of cellular component size GO:0032535 98 0.017
rrna processing GO:0006364 3 0.017
rhythmic behavior GO:0007622 76 0.017
negative regulation of stem cell proliferation GO:2000647 30 0.016
lateral inhibition GO:0046331 206 0.016
positive regulation of phosphorylation GO:0042327 87 0.016
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
molting cycle GO:0042303 56 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
regulation of protein transport GO:0051223 57 0.016
jak stat cascade GO:0007259 49 0.016
neuron death GO:0070997 27 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
regulation of protein import into nucleus GO:0042306 28 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
response to dsrna GO:0043331 15 0.016
regulation of cellular response to oxidative stress GO:1900407 4 0.016
ovarian follicle cell development GO:0030707 248 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
Fly
production of sirna involved in rna interference GO:0030422 11 0.016
response to ionizing radiation GO:0010212 32 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
oocyte axis specification GO:0007309 108 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
cell proliferation GO:0008283 299 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
inorganic cation transmembrane transport GO:0098662 61 0.016
leucine transport GO:0015820 3 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
eye morphogenesis GO:0048592 260 0.015
cell adhesion GO:0007155 136 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
compound eye morphogenesis GO:0001745 249 0.015
heterocycle catabolic process GO:0046700 166 0.015
response to mechanical stimulus GO:0009612 28 0.015
regulation of cell shape GO:0008360 113 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
cell motility GO:0048870 251 0.015
positive regulation of cell death GO:0010942 69 0.015
positive regulation of transport GO:0051050 92 0.015
cognition GO:0050890 141 0.015
regulation of steroid metabolic process GO:0019218 2 0.015
regulation of programmed cell death GO:0043067 152 0.014
negative regulation of chromosome organization GO:2001251 19 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
transmembrane transport GO:0055085 139 0.014
chromatin remodeling GO:0006338 72 0.014
negative regulation of developmental process GO:0051093 201 0.014
digestive tract development GO:0048565 149 0.014
salivary gland morphogenesis GO:0007435 145 0.014
cell maturation GO:0048469 144 0.014
organelle assembly GO:0070925 198 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
ocellus pigment metabolic process GO:0046158 19 0.014
nucleotide metabolic process GO:0009117 161 0.014
regulation of response to oxidative stress GO:1902882 4 0.014
regulation of transcription by chromatin organization GO:0034401 3 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
adult chitin containing cuticle pigmentation GO:0048085 16 0.014
regulation of multicellular organism growth GO:0040014 40 0.014
nitrogen compound transport GO:0071705 85 0.014
response to heat GO:0009408 63 0.014
substrate adhesion dependent cell spreading GO:0034446 2 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
mitotic g2 dna damage checkpoint GO:0007095 69 0.014
regulation of reactive oxygen species metabolic process GO:2000377 8 0.014
circadian sleep wake cycle GO:0042745 28 0.014
negative regulation of growth GO:0045926 84 0.013

PGRP-LC disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
disease of cellular proliferation DOID:14566 0 0.026
sensory system disease DOID:0050155 0 0.026
eye and adnexa disease DOID:1492 0 0.026
nervous system disease DOID:863 0 0.026
eye disease DOID:5614 0 0.026
heart conduction disease DOID:10273 0 0.025
cardiovascular system disease DOID:1287 0 0.025
cancer DOID:162 0 0.024
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
immune system disease DOID:2914 0 0.016
organ system cancer DOID:0050686 0 0.016