Drosophila melanogaster

173 known processes

unc-104 (Dmel_CG8566)

CG8566 gene product from transcript CG8566-RB

(Aliases: Unc104,KIF1B,Dmel\CG8566,Klp53D,DmKlp53D,CG8566,imac,DmCG8566,Dunc104,Unc-104)

unc-104 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.998
establishment of vesicle localization GO:0051650 51 0.997
axonogenesis GO:0007409 290 0.997
synaptic vesicle transport GO:0048489 50 0.993
establishment of synaptic vesicle localization GO:0097480 50 0.980
synaptic vesicle recycling GO:0036465 28 0.978
axon development GO:0061564 297 0.975
taxis GO:0042330 304 0.973
regulation of synaptic transmission GO:0050804 69 0.968
synaptic vesicle localization GO:0097479 53 0.967
establishment of organelle localization GO:0051656 122 0.967
regulation of synapse organization GO:0050807 110 0.959
synaptic vesicle exocytosis GO:0016079 16 0.959
synapse organization GO:0050808 196 0.958
establishment of localization in cell GO:0051649 402 0.954
chemotaxis GO:0006935 249 0.945
regulation of synapse assembly GO:0051963 94 0.907
neurotransmitter transport GO:0006836 37 0.907
synapse assembly GO:0007416 143 0.887
neuron projection guidance GO:0097485 241 0.857
developmental growth GO:0048589 280 0.855
vesicle localization GO:0051648 55 0.850
secretion by cell GO:0032940 101 0.841
synaptic vesicle endocytosis GO:0048488 28 0.840
axon guidance GO:0007411 233 0.836
secretion GO:0046903 109 0.811
neuromuscular junction development GO:0007528 149 0.809
organelle localization GO:0051640 148 0.790
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.719
positive regulation of nervous system development GO:0051962 69 0.680
Worm
neuron neuron synaptic transmission GO:0007270 14 0.677
Mouse Worm
neurotransmitter secretion GO:0007269 35 0.667
small molecule metabolic process GO:0044281 305 0.644
Mouse
signal release GO:0023061 49 0.616
positive regulation of synapse assembly GO:0051965 29 0.615
Worm
growth GO:0040007 359 0.608
regulation of nervous system development GO:0051960 248 0.586
cognition GO:0050890 141 0.584
regulation of synapse structure and activity GO:0050803 128 0.554
single organism membrane organization GO:0044802 93 0.514
Worm
endomembrane system organization GO:0010256 119 0.514
vesicle organization GO:0016050 44 0.497
positive regulation of signaling GO:0023056 243 0.474
regulation of catabolic process GO:0009894 170 0.468
learning or memory GO:0007611 141 0.449
membrane organization GO:0061024 112 0.447
Worm
cell growth GO:0016049 108 0.445
Zebrafish Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.444
organic cyclic compound catabolic process GO:1901361 168 0.428
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 108 0.416
Mouse
protein transport GO:0015031 155 0.411
exocytosis GO:0006887 28 0.406
Worm
positive regulation of cell communication GO:0010647 250 0.405
positive regulation of cellular component organization GO:0051130 156 0.401
Worm
cellular macromolecule localization GO:0070727 220 0.398
Zebrafish Worm
peptidyl amino acid modification GO:0018193 105 0.385
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.376
actin filament based process GO:0030029 220 0.376
maintenance of presynaptic active zone structure GO:0048790 8 0.372
positive regulation of synaptic transmission GO:0050806 15 0.361
protein localization GO:0008104 284 0.349
Worm
regulation of vesicle mediated transport GO:0060627 59 0.347
organophosphate catabolic process GO:0046434 112 0.336
Mouse
neuromuscular synaptic transmission GO:0007274 67 0.329
Mouse
intracellular transport GO:0046907 228 0.326
cortical cytoskeleton organization GO:0030865 29 0.326
axon extension GO:0048675 32 0.318
Zebrafish Worm
cellular catabolic process GO:0044248 372 0.316
Mouse
developmental maturation GO:0021700 172 0.306
single organism carbohydrate metabolic process GO:0044723 72 0.301
organonitrogen compound metabolic process GO:1901564 318 0.299
Mouse
organic substance catabolic process GO:1901575 308 0.298
Mouse
cellular protein modification process GO:0006464 438 0.296
negative regulation of synapse assembly GO:0051964 39 0.295
negative regulation of response to stimulus GO:0048585 258 0.295
single organism catabolic process GO:0044712 228 0.290
Mouse
catabolic process GO:0009056 409 0.290
Mouse
neuron projection extension GO:1990138 32 0.288
Zebrafish Worm
regulation of neuromuscular synaptic transmission GO:1900073 15 0.287
regulation of dendrite morphogenesis GO:0048814 28 0.286
heterocycle catabolic process GO:0046700 166 0.283
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.276
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.269
Mouse
organonitrogen compound catabolic process GO:1901565 128 0.261
Mouse
regulation of localization GO:0032879 275 0.256
regulation of terminal button organization GO:2000331 11 0.230
defense response to other organism GO:0098542 225 0.229
organic substance transport GO:0071702 257 0.228
cellular nitrogen compound catabolic process GO:0044270 165 0.227
Mouse
protein modification process GO:0036211 438 0.224
oocyte differentiation GO:0009994 145 0.223
regulation of neurotransmitter levels GO:0001505 38 0.216
purine ribonucleoside catabolic process GO:0046130 112 0.215
Mouse
carbohydrate metabolic process GO:0005975 82 0.208
purine nucleotide catabolic process GO:0006195 109 0.207
Mouse
macromolecule catabolic process GO:0009057 161 0.206
regulation of transport GO:0051049 181 0.206
regulation of neurogenesis GO:0050767 158 0.205
vesicle mediated transport GO:0016192 381 0.195
ribonucleoside metabolic process GO:0009119 127 0.195
Mouse
response to light stimulus GO:0009416 124 0.195
tissue migration GO:0090130 155 0.194
glycosyl compound catabolic process GO:1901658 112 0.187
Mouse
nucleotide catabolic process GO:0009166 109 0.181
Mouse
regulation of behavior GO:0050795 75 0.181
negative regulation of developmental growth GO:0048640 64 0.179
regulation of cellular catabolic process GO:0031329 157 0.178
memory GO:0007613 94 0.176
positive regulation of multicellular organismal process GO:0051240 143 0.169
Worm
immune system process GO:0002376 347 0.167
enzyme linked receptor protein signaling pathway GO:0007167 179 0.161
carbohydrate derivative catabolic process GO:1901136 118 0.159
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.158
regulation of cellular component biogenesis GO:0044087 201 0.152
transcription from rna polymerase ii promoter GO:0006366 368 0.151
vitamin transport GO:0051180 2 0.151
nucleotide metabolic process GO:0009117 161 0.147
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.145
lipid modification GO:0030258 24 0.145
multi organism behavior GO:0051705 175 0.141
circulatory system development GO:0072359 82 0.139
cell migration GO:0016477 238 0.138
synaptic growth at neuromuscular junction GO:0051124 119 0.137
purine ribonucleotide catabolic process GO:0009154 109 0.135
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.134
Mouse
adult locomotory behavior GO:0008344 76 0.132
glycosyl compound metabolic process GO:1901657 127 0.132
Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.132
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.131
guanosine containing compound metabolic process GO:1901068 74 0.131
gtp catabolic process GO:0006184 72 0.129
actin cytoskeleton organization GO:0030036 206 0.129
organelle fusion GO:0048284 46 0.126
olfactory learning GO:0008355 56 0.126
positive regulation of gtp catabolic process GO:0033126 43 0.126
aromatic compound catabolic process GO:0019439 166 0.125
Mouse
positive regulation of axon guidance GO:1902669 1 0.122
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.119
positive regulation of transport GO:0051050 92 0.118
response to radiation GO:0009314 155 0.118
positive regulation of nucleotide catabolic process GO:0030813 46 0.117
learning GO:0007612 75 0.116
r7 cell differentiation GO:0045466 43 0.115
purine ribonucleoside metabolic process GO:0046128 127 0.115
Mouse
oocyte development GO:0048599 124 0.112
purine nucleoside metabolic process GO:0042278 127 0.111
Mouse
positive regulation of developmental process GO:0051094 143 0.110
Worm
regulation of cell morphogenesis GO:0022604 163 0.109
dendrite morphogenesis GO:0048813 199 0.107
epithelium migration GO:0090132 148 0.107
regulation of peptide secretion GO:0002791 6 0.107
endocytosis GO:0006897 310 0.105
regulation of endocytosis GO:0030100 37 0.105
positive regulation of cell migration GO:0030335 2 0.105
cellular response to chemical stimulus GO:0070887 199 0.105
positive regulation of cellular component biogenesis GO:0044089 80 0.105
Worm
positive regulation of phosphate metabolic process GO:0045937 139 0.100
homeostatic process GO:0042592 199 0.100
cell adhesion GO:0007155 136 0.100
purine nucleoside triphosphate metabolic process GO:0009144 119 0.098
Mouse
negative regulation of nervous system development GO:0051961 92 0.097
developmental growth involved in morphogenesis GO:0060560 65 0.097
Zebrafish Worm
regulation of cell differentiation GO:0045595 302 0.096
nucleoside metabolic process GO:0009116 127 0.096
Mouse
cellular protein complex assembly GO:0043623 71 0.096
positive regulation of cell motility GO:2000147 3 0.096
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.095
Worm
associative learning GO:0008306 65 0.095
positive regulation of response to stimulus GO:0048584 323 0.094
cellular macromolecular complex assembly GO:0034622 153 0.093
positive regulation of cell death GO:0010942 69 0.093
Worm
epithelial cell migration GO:0010631 148 0.092
nucleoside catabolic process GO:0009164 112 0.092
Mouse
peptidyl threonine phosphorylation GO:0018107 2 0.092
macromolecular complex assembly GO:0065003 256 0.091
establishment of protein localization GO:0045184 163 0.091
actin filament organization GO:0007015 126 0.090
rho protein signal transduction GO:0007266 14 0.090
organophosphate metabolic process GO:0019637 195 0.089
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.089
Mouse
regulation of purine nucleotide catabolic process GO:0033121 48 0.087
nucleobase containing small molecule metabolic process GO:0055086 174 0.087
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.086
positive regulation of gtpase activity GO:0043547 43 0.086
nucleoside phosphate metabolic process GO:0006753 162 0.084
Mouse
single organism intracellular transport GO:1902582 207 0.084
regulation of epithelial cell proliferation GO:0050678 4 0.083
cell motility GO:0048870 251 0.083
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.082
ribonucleoside triphosphate metabolic process GO:0009199 119 0.081
Mouse
locomotory behavior GO:0007626 176 0.079
regulation of epithelial cell migration GO:0010632 12 0.078
membrane tubulation GO:0097320 4 0.077
cellular component maintenance GO:0043954 23 0.077
positive regulation of neurogenesis GO:0050769 41 0.076
protein complex biogenesis GO:0070271 201 0.075
nucleobase containing compound catabolic process GO:0034655 165 0.075
Mouse
ribonucleoside catabolic process GO:0042454 112 0.075
Mouse
purine containing compound catabolic process GO:0072523 112 0.073
Mouse
positive regulation of synaptic vesicle recycling GO:1903423 4 0.073
regulation of cellular localization GO:0060341 136 0.071
nucleoside phosphate catabolic process GO:1901292 110 0.071
Mouse
positive regulation of growth GO:0045927 75 0.071
Worm
negative regulation of autophagy GO:0010507 16 0.071
ribonucleotide catabolic process GO:0009261 109 0.070
Mouse
cellular protein localization GO:0034613 160 0.070
Worm
regulation of secretion by cell GO:1903530 39 0.069
regulation of intracellular signal transduction GO:1902531 236 0.069
chromosome organization GO:0051276 360 0.069
Fly
guanosine containing compound catabolic process GO:1901069 74 0.068
regulation of actin cytoskeleton organization GO:0032956 42 0.067
regulation of phosphate metabolic process GO:0019220 210 0.067
positive regulation of cell projection organization GO:0031346 29 0.067
centrosome organization GO:0051297 163 0.067
compound eye morphogenesis GO:0001745 249 0.065
cellular response to starvation GO:0009267 61 0.065
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.065
Mouse
regulation of notch signaling pathway GO:0008593 100 0.064
positive regulation of nucleoside metabolic process GO:0045979 47 0.063
ribonucleotide metabolic process GO:0009259 145 0.062
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.061
negative regulation of growth GO:0045926 84 0.060
establishment of protein localization to plasma membrane GO:0090002 9 0.060
mapk cascade GO:0000165 107 0.059
purine nucleoside catabolic process GO:0006152 112 0.059
Mouse
regulation of necrotic cell death GO:0010939 1 0.059
Worm
cell maturation GO:0048469 144 0.058
protein catabolic process GO:0030163 101 0.058
axon target recognition GO:0007412 16 0.057
protein complex disassembly GO:0043241 36 0.057
purine ribonucleotide metabolic process GO:0009150 145 0.056
Mouse
compound eye photoreceptor development GO:0042051 78 0.056
meiosis i GO:0007127 59 0.056
regulation of phosphorus metabolic process GO:0051174 210 0.055
extracellular matrix organization GO:0030198 32 0.055
positive regulation of molecular function GO:0044093 136 0.055
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
phosphorylation GO:0016310 294 0.054
oocyte axis specification GO:0007309 108 0.054
protein phosphorylation GO:0006468 169 0.054
ribose phosphate metabolic process GO:0019693 145 0.054
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.054
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.053
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.052
regulation of nucleotide metabolic process GO:0006140 62 0.052
eye morphogenesis GO:0048592 260 0.052
negative regulation of neuroblast proliferation GO:0007406 27 0.052
gtp metabolic process GO:0046039 72 0.052
regulation of neuron differentiation GO:0045664 103 0.052
regulation of catalytic activity GO:0050790 185 0.052
positive regulation of biosynthetic process GO:0009891 316 0.052
cell death GO:0008219 279 0.052
Worm
multicellular organismal reproductive behavior GO:0033057 110 0.052
regulation of cell projection organization GO:0031344 92 0.051
intracellular signal transduction GO:0035556 300 0.050
regulation of synaptic plasticity GO:0048167 14 0.049
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.049
cytoplasmic transport GO:0016482 130 0.049
regulation of molecular function GO:0065009 217 0.048
neurological system process GO:0050877 358 0.048
positive regulation of signal transduction GO:0009967 223 0.048
regulation of cell cycle phase transition GO:1901987 130 0.047
negative regulation of cellular metabolic process GO:0031324 382 0.047
positive regulation of catalytic activity GO:0043085 118 0.047
motor neuron axon guidance GO:0008045 58 0.046
programmed cell death GO:0012501 257 0.046
peripheral nervous system development GO:0007422 52 0.045
Zebrafish
r7 cell development GO:0045467 14 0.045
positive regulation of phosphorus metabolic process GO:0010562 139 0.044
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.044
metal ion homeostasis GO:0055065 44 0.044
defense response to gram negative bacterium GO:0050829 94 0.044
regulation of hydrolase activity GO:0051336 97 0.044
developmental cell growth GO:0048588 52 0.044
Zebrafish Worm
extracellular structure organization GO:0043062 46 0.044
negative regulation of immune system process GO:0002683 50 0.043
cell division GO:0051301 248 0.043
brain development GO:0007420 120 0.043
regulation of cell death GO:0010941 173 0.043
Worm
regulation of cytoskeleton organization GO:0051493 89 0.042
positive regulation of secretion by cell GO:1903532 20 0.042
positive regulation of nucleotide metabolic process GO:0045981 55 0.042
regulation of synaptic vesicle exocytosis GO:2000300 3 0.041
necrotic cell death GO:0070265 1 0.041
Worm
flight behavior GO:0007629 26 0.041
regulation of gtp catabolic process GO:0033124 44 0.041
eye photoreceptor cell differentiation GO:0001754 145 0.041
ameboidal type cell migration GO:0001667 151 0.040
positive regulation of cellular catabolic process GO:0031331 95 0.040
segmentation GO:0035282 207 0.040
positive regulation of cell development GO:0010720 61 0.040
multi multicellular organism process GO:0044706 123 0.040
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.040
signal transduction by phosphorylation GO:0023014 107 0.039
regulation of actin filament based process GO:0032970 42 0.039
regulation of protein complex disassembly GO:0043244 29 0.038
neuron maturation GO:0042551 31 0.038
mitotic nuclear division GO:0007067 213 0.038
Fly
maternal determination of anterior posterior axis embryo GO:0008358 74 0.038
body morphogenesis GO:0010171 2 0.037
Worm
protein depolymerization GO:0051261 31 0.037
multicellular organismal aging GO:0010259 140 0.037
notch signaling pathway GO:0007219 120 0.037
intracellular protein transport GO:0006886 104 0.037
regulation of protein metabolic process GO:0051246 256 0.036
terminal button organization GO:0072553 19 0.036
negative regulation of rho protein signal transduction GO:0035024 1 0.036
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.036
peptidyl threonine modification GO:0018210 3 0.036
axon extension involved in axon guidance GO:0048846 10 0.036
cation transport GO:0006812 110 0.035
single organismal cell cell adhesion GO:0016337 45 0.035
single organism cellular localization GO:1902580 180 0.035
photoreceptor cell differentiation GO:0046530 170 0.035
chromatin modification GO:0016568 147 0.035
purine nucleotide metabolic process GO:0006163 146 0.035
Mouse
regulation of synaptic vesicle endocytosis GO:1900242 7 0.034
cellular macromolecule catabolic process GO:0044265 136 0.034
feeding behavior GO:0007631 50 0.034
Worm
regulation of autophagy GO:0010506 62 0.033
regulation of synaptic vesicle transport GO:1902803 10 0.033
multi organism reproductive behavior GO:0044705 121 0.033
regulation of organelle organization GO:0033043 196 0.032
imaginal disc derived wing morphogenesis GO:0007476 337 0.032
positive regulation of neurotransmitter secretion GO:0001956 2 0.032
positive regulation of hydrolase activity GO:0051345 78 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.032
actin polymerization or depolymerization GO:0008154 31 0.032
dephosphorylation GO:0016311 51 0.031
innate immune response GO:0045087 144 0.031
stem cell development GO:0048864 79 0.031
positive regulation of cellular amine metabolic process GO:0033240 0 0.031
detection of stimulus GO:0051606 156 0.030
regulation of cellular response to stress GO:0080135 89 0.030
dendrite development GO:0016358 204 0.030
nuclear division GO:0000280 332 0.030
Fly
ion homeostasis GO:0050801 55 0.030
negative regulation of signaling GO:0023057 219 0.029
positive regulation of ras gtpase activity GO:0032320 36 0.029
regulation of response to stress GO:0080134 200 0.029
photoreceptor cell development GO:0042461 96 0.029
lateral inhibition GO:0046331 206 0.029
modification dependent macromolecule catabolic process GO:0043632 79 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
maintenance of location GO:0051235 73 0.029
release of sequestered calcium ion into cytosol GO:0051209 1 0.029
protein complex assembly GO:0006461 200 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
amine metabolic process GO:0009308 12 0.029
mitotic cell cycle checkpoint GO:0007093 88 0.028
regulation of establishment of protein localization GO:0070201 61 0.028
response to reactive oxygen species GO:0000302 24 0.028
macroautophagy GO:0016236 42 0.028
chromatin organization GO:0006325 207 0.028
circulatory system process GO:0003013 37 0.028
forebrain development GO:0030900 2 0.028
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.028
adult walking behavior GO:0007628 9 0.028
cellular lipid metabolic process GO:0044255 83 0.028
regulation of nucleoside metabolic process GO:0009118 50 0.028
conditioned taste aversion GO:0001661 3 0.027
regulation of protein localization GO:0032880 76 0.027
germarium derived egg chamber formation GO:0007293 101 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.027
defense response GO:0006952 300 0.027
hindbrain development GO:0030902 2 0.027
aging GO:0007568 143 0.027
regulation of protein transport GO:0051223 57 0.027
positive regulation of catabolic process GO:0009896 105 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.027
positive regulation of developmental growth GO:0048639 62 0.026
Worm
ubiquitin dependent protein catabolic process GO:0006511 78 0.026
determination of adult lifespan GO:0008340 137 0.026
localization of cell GO:0051674 257 0.026
oocyte construction GO:0007308 112 0.026
regulation of response to external stimulus GO:0032101 115 0.025
response to starvation GO:0042594 97 0.025
regulation of neurotransmitter secretion GO:0046928 14 0.025
plasma membrane organization GO:0007009 26 0.025
regulation of membrane potential GO:0042391 35 0.025
negative regulation of immune response GO:0050777 39 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
monocarboxylic acid transport GO:0015718 3 0.024
response to growth factor GO:0070848 31 0.024
response to external biotic stimulus GO:0043207 293 0.024
oviposition GO:0018991 19 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
organelle fission GO:0048285 340 0.024
Fly
ion transport GO:0006811 145 0.024
macromolecular complex disassembly GO:0032984 37 0.024
asymmetric protein localization GO:0008105 33 0.024
open tracheal system development GO:0007424 204 0.024
larval locomotory behavior GO:0008345 27 0.024
cellular homeostasis GO:0019725 80 0.023
branching involved in open tracheal system development GO:0060446 45 0.023
photoreceptor cell axon guidance GO:0072499 23 0.023
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
regulation of phosphorylation GO:0042325 147 0.023
positive regulation of axonogenesis GO:0050772 2 0.023
meiotic cell cycle process GO:1903046 132 0.023
erbb signaling pathway GO:0038127 58 0.023
cellular response to extracellular stimulus GO:0031668 64 0.023
mitotic cell cycle phase transition GO:0044772 138 0.023
peptidyl lysine modification GO:0018205 57 0.023
regulation of gtpase activity GO:0043087 44 0.023
negative regulation of cell cycle phase transition GO:1901988 103 0.023
neuromuscular process GO:0050905 21 0.023
modification dependent protein catabolic process GO:0019941 78 0.023
anterograde synaptic vesicle transport GO:0048490 3 0.023
defense response to bacterium GO:0042742 178 0.023
oocyte maturation GO:0001556 3 0.023
cell cycle checkpoint GO:0000075 95 0.022
positive regulation of organelle organization GO:0010638 65 0.022
regulation of cellular component movement GO:0051270 42 0.022
oocyte fate determination GO:0030716 27 0.022
regulation of secretion GO:0051046 44 0.022
regulation of anatomical structure morphogenesis GO:0022603 242 0.022
regulation of cell adhesion GO:0030155 27 0.022
blastoderm segmentation GO:0007350 159 0.022
cellular divalent inorganic cation homeostasis GO:0072503 23 0.022
immune response GO:0006955 246 0.022
negative regulation of homeostatic process GO:0032845 2 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
regulation of ras protein signal transduction GO:0046578 93 0.021
golgi vesicle transport GO:0048193 27 0.021
cellular protein catabolic process GO:0044257 83 0.021
autophagy GO:0006914 108 0.021
regulation of purine nucleotide metabolic process GO:1900542 62 0.021
cell cycle phase transition GO:0044770 140 0.021
regulation of receptor mediated endocytosis GO:0048259 9 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
Fly
regulation of cell substrate adhesion GO:0010810 2 0.021
phagocytosis GO:0006909 215 0.020
positive regulation of exocytosis GO:0045921 4 0.020
ras protein signal transduction GO:0007265 88 0.020
cellular amine metabolic process GO:0044106 12 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.020
trachea development GO:0060438 29 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
actomyosin structure organization GO:0031032 56 0.020
regulation of cell cycle GO:0051726 291 0.020
Fly
synaptic transmission glutamatergic GO:0035249 7 0.020
negative regulation of gene expression GO:0010629 387 0.019
response to axon injury GO:0048678 12 0.019
regulation of receptor activity GO:0010469 10 0.019
positive regulation of gene expression GO:0010628 290 0.019
regulation of transmembrane transport GO:0034762 27 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
axon midline choice point recognition GO:0016199 26 0.019
oxoacid metabolic process GO:0043436 103 0.019
negative regulation of protein complex disassembly GO:0043242 23 0.019
regulation of nucleotide catabolic process GO:0030811 48 0.019
organic acid metabolic process GO:0006082 103 0.019
cellular response to nutrient levels GO:0031669 62 0.019
oocyte anterior posterior axis specification GO:0007314 72 0.019
eye antennal disc morphogenesis GO:0007455 34 0.019
regulation of intracellular transport GO:0032386 64 0.019
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.019
cellular cation homeostasis GO:0030003 38 0.018
regulation of cellular component size GO:0032535 98 0.018
Worm
stem cell differentiation GO:0048863 117 0.018
negative regulation of catabolic process GO:0009895 36 0.018
compound eye development GO:0048749 307 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
epidermal growth factor receptor signaling pathway GO:0007173 58 0.018
regulation of protein complex assembly GO:0043254 42 0.018
regulation of nurse cell apoptotic process GO:0045477 9 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
stress activated protein kinase signaling cascade GO:0031098 55 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
regulation of cell development GO:0060284 215 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.017
regulation of lipid metabolic process GO:0019216 15 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.017
regulation of developmental growth GO:0048638 174 0.017
proteolysis GO:0006508 192 0.017
protein localization to synapse GO:0035418 1 0.017
regulation of glutamate receptor signaling pathway GO:1900449 1 0.016
adult behavior GO:0030534 137 0.016
cellular ion homeostasis GO:0006873 39 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
single organism membrane fusion GO:0044801 42 0.016
anterior posterior axis specification GO:0009948 109 0.016
protein localization to plasma membrane GO:0072659 13 0.016
neuron cell cell adhesion GO:0007158 1 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
germ cell migration GO:0008354 43 0.016

unc-104 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
Human
nervous system disease DOID:863 0 0.045
Human
cancer DOID:162 0 0.036
Human
disease of cellular proliferation DOID:14566 0 0.036
Human
organ system cancer DOID:0050686 0 0.017
Human
central nervous system disease DOID:331 0 0.016