Drosophila melanogaster

305 known processes

arm (Dmel_CG11579)

armadillo

(Aliases: l(1)G0234,Dmel\CG11579,beta-cat-arm,CG11579,beta-cat,l(1)2Bv,l(1)G0192,ARM,betacat,t12687 ALR Dm,l(1)G0410,l(1)arm,beta-Cat,EG:86E4.6,Arm)

arm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived egg chamber formation GO:0007293 101 1.000
tube development GO:0035295 244 1.000
tube morphogenesis GO:0035239 191 0.999
respiratory system development GO:0060541 213 0.999
oocyte differentiation GO:0009994 145 0.999
Mouse
ovarian follicle cell migration GO:0007297 121 0.999
embryonic morphogenesis GO:0048598 206 0.999
border follicle cell migration GO:0007298 113 0.998
digestive tract development GO:0048565 149 0.997
sensory organ morphogenesis GO:0090596 260 0.997
anterior posterior axis specification GO:0009948 109 0.997
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.997
protein complex assembly GO:0006461 200 0.997
cell motility GO:0048870 251 0.997
Human Mouse Worm
embryonic development via the syncytial blastoderm GO:0001700 148 0.996
oocyte construction GO:0007308 112 0.996
meiotic nuclear division GO:0007126 151 0.994
meiotic cell cycle GO:0051321 171 0.994
branching morphogenesis of an epithelial tube GO:0048754 45 0.993
morphogenesis of a branching epithelium GO:0061138 45 0.992
neurological system process GO:0050877 358 0.988
multicellular organismal reproductive behavior GO:0033057 110 0.988
Worm
open tracheal system development GO:0007424 204 0.988
oocyte axis specification GO:0007309 108 0.987
appendage morphogenesis GO:0035107 397 0.985
anterior posterior pattern specification GO:0009952 136 0.985
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.983
sex differentiation GO:0007548 81 0.982
Mouse Worm
axis specification GO:0009798 167 0.981
Zebrafish Mouse Worm
protein complex biogenesis GO:0070271 201 0.979
spermatid differentiation GO:0048515 114 0.979
embryonic pattern specification GO:0009880 174 0.977
Zebrafish Mouse
biological adhesion GO:0022610 138 0.976
muscle cell differentiation GO:0042692 103 0.976
Mouse
germarium derived female germ line cyst formation GO:0030727 42 0.976
dna metabolic process GO:0006259 227 0.975
Mouse
cell division GO:0051301 248 0.973
regulation of cell morphogenesis GO:0022604 163 0.971
regulation of developmental growth GO:0048638 174 0.970
forebrain development GO:0030900 2 0.970
Mouse
female germ line cyst formation GO:0048135 42 0.967
morphogenesis of an epithelium GO:0002009 276 0.967
branching involved in open tracheal system development GO:0060446 45 0.966
blastoderm segmentation GO:0007350 159 0.966
tissue morphogenesis GO:0048729 297 0.965
regulation of organ morphogenesis GO:2000027 78 0.965
digestive tract morphogenesis GO:0048546 127 0.962
r3 r4 cell fate commitment GO:0007464 10 0.959
reproductive structure development GO:0048608 74 0.955
Mouse Worm
cytoskeleton dependent cytokinesis GO:0061640 81 0.955
appendage development GO:0048736 401 0.953
actin cytoskeleton organization GO:0030036 206 0.947
Worm
photoreceptor cell differentiation GO:0046530 170 0.946
central nervous system development GO:0007417 201 0.935
Mouse
positive regulation of developmental process GO:0051094 143 0.929
oocyte microtubule cytoskeleton organization GO:0016325 35 0.928
gonad development GO:0008406 50 0.923
Worm
ovarian follicle cell development GO:0030707 248 0.922
cell migration GO:0016477 238 0.917
Human Mouse Worm
body morphogenesis GO:0010171 2 0.914
Worm
negative regulation of cardioblast differentiation GO:0051892 7 0.910
larval development GO:0002164 104 0.905
nuclear division GO:0000280 332 0.899
heart induction GO:0003129 3 0.889
embryonic organ development GO:0048568 50 0.889
Mouse
establishment of planar polarity GO:0001736 87 0.884
reproductive behavior GO:0019098 122 0.875
Worm
segmentation GO:0035282 207 0.874
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.870
heart development GO:0007507 82 0.870
epidermis development GO:0008544 65 0.865
Mouse
skin development GO:0043588 65 0.864
Mouse
negative regulation of cell development GO:0010721 62 0.863
Mouse
cell proliferation GO:0008283 299 0.859
pole plasm mrna localization GO:0019094 49 0.858
digestive system development GO:0055123 149 0.852
cellular macromolecular complex assembly GO:0034622 153 0.839
epithelial tube morphogenesis GO:0060562 88 0.836
glial cell migration GO:0008347 31 0.836
gliogenesis GO:0042063 80 0.834
Mouse
multicellular organism growth GO:0035264 46 0.833
male gamete generation GO:0048232 201 0.815
cell adhesion GO:0007155 136 0.811
regulation of multicellular organismal development GO:2000026 414 0.809
gastrulation GO:0007369 70 0.797
germarium derived oocyte fate determination GO:0007294 26 0.793
cardiovascular system development GO:0072358 82 0.791
regulation of organelle organization GO:0033043 196 0.784
Human Mouse Worm
establishment of tissue polarity GO:0007164 87 0.783
muscle structure development GO:0061061 224 0.778
Mouse
macromolecular complex assembly GO:0065003 256 0.774
protein transport GO:0015031 155 0.773
Human
protein targeting GO:0006605 64 0.762
Human
cell junction assembly GO:0034329 42 0.761
establishment of ommatidial planar polarity GO:0042067 49 0.761
establishment of organelle localization GO:0051656 122 0.761
Mouse
developmental growth GO:0048589 280 0.759
motor neuron axon guidance GO:0008045 58 0.758
positive regulation of cellular component organization GO:0051130 156 0.758
Human
reproductive system development GO:0061458 74 0.755
Mouse Worm
regulation of cell development GO:0060284 215 0.755
Human Mouse
axon development GO:0061564 297 0.755
regulation of membrane potential GO:0042391 35 0.752
Human
dorsal closure elongation of leading edge cells GO:0007394 10 0.750
negative regulation of neurogenesis GO:0050768 53 0.748
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.747
Mouse
ameboidal type cell migration GO:0001667 151 0.746
Worm
pole plasm rna localization GO:0007316 52 0.745
organelle fission GO:0048285 340 0.732
renal system development GO:0072001 72 0.730
Mouse
brain development GO:0007420 120 0.727
Mouse
regulation of wnt signaling pathway GO:0030111 68 0.726
Zebrafish
organelle localization GO:0051640 148 0.720
Mouse
initiation of dorsal closure GO:0007392 12 0.719
regulation of cell division GO:0051302 72 0.719
positive regulation of macromolecule metabolic process GO:0010604 405 0.717
response to oxygen containing compound GO:1901700 200 0.713
Human
guanosine containing compound metabolic process GO:1901068 74 0.709
regulation of heart induction GO:0090381 3 0.709
negative regulation of cell differentiation GO:0045596 143 0.705
multi organism behavior GO:0051705 175 0.705
Worm
transcription from rna polymerase ii promoter GO:0006366 368 0.700
establishment or maintenance of cell polarity GO:0007163 167 0.690
positive regulation of cell proliferation GO:0008284 47 0.684
Mouse
eggshell chorion assembly GO:0007306 66 0.682
multicellular organismal aging GO:0010259 140 0.680
axis elongation GO:0003401 3 0.675
localization of cell GO:0051674 257 0.673
Human Mouse Worm
regulation of intracellular signal transduction GO:1902531 236 0.670
Mouse
actin filament based process GO:0030029 220 0.666
Worm
morphogenesis of a polarized epithelium GO:0001738 93 0.651
epithelial cell migration GO:0010631 148 0.649
death GO:0016265 284 0.648
epithelial cell differentiation GO:0030855 322 0.638
Mouse
oocyte development GO:0048599 124 0.636
Mouse
regulation of anatomical structure size GO:0090066 163 0.635
cytokinesis GO:0000910 90 0.632
germ line cyst formation GO:0048134 44 0.627
genitalia development GO:0048806 26 0.623
Mouse Worm
r3 r4 cell differentiation GO:0048056 12 0.623
negative regulation of cellular metabolic process GO:0031324 382 0.620
Human Mouse
wnt signaling pathway GO:0016055 98 0.616
negative regulation of nucleic acid templated transcription GO:1903507 240 0.609
Human Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.605
spermatogenesis GO:0007283 200 0.602
morphogenesis of embryonic epithelium GO:0016331 94 0.594
protein localization to nucleus GO:0034504 55 0.593
Human
regulation of cellular component biogenesis GO:0044087 201 0.583
actin filament bundle organization GO:0061572 28 0.580
spermatid development GO:0007286 98 0.580
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.577
negative regulation of multicellular organismal process GO:0051241 142 0.574
protein targeting to nucleus GO:0044744 51 0.563
Human
negative regulation of nervous system development GO:0051961 92 0.560
Mouse
regulation of notch signaling pathway GO:0008593 100 0.559
regionalization GO:0003002 416 0.554
regulation of cell shape GO:0008360 113 0.554
regulation of tube size GO:0035150 46 0.553
positive regulation of signal transduction GO:0009967 223 0.545
Mouse
intracellular signal transduction GO:0035556 300 0.545
Mouse Worm
dendrite regeneration GO:0031104 2 0.544
positive regulation of nervous system development GO:0051962 69 0.542
Mouse
morphogenesis of a branching structure GO:0001763 45 0.541
organ induction GO:0001759 3 0.541
convergent extension GO:0060026 2 0.540
Zebrafish
ensheathment of neurons GO:0007272 10 0.540
Mouse
oocyte morphogenesis GO:0048601 3 0.539
ribonucleoside triphosphate catabolic process GO:0009203 108 0.537
regulation of establishment of planar polarity GO:0090175 22 0.533
regulation of proteasomal protein catabolic process GO:0061136 39 0.525
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.524
morphogenesis of follicular epithelium GO:0016333 36 0.524
gland morphogenesis GO:0022612 145 0.524
cell projection assembly GO:0030031 94 0.517
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.514
mitotic cytokinesis GO:0000281 50 0.495
eye morphogenesis GO:0048592 260 0.495
dorsal closure GO:0007391 79 0.493
axonogenesis GO:0007409 290 0.493
negative regulation of signal transduction GO:0009968 206 0.488
Zebrafish Mouse
regulation of dna metabolic process GO:0051052 34 0.484
Mouse
non canonical wnt signaling pathway GO:0035567 8 0.480
nucleotide catabolic process GO:0009166 109 0.479
spindle organization GO:0007051 253 0.479
Worm
determination of adult lifespan GO:0008340 137 0.476
purine nucleoside catabolic process GO:0006152 112 0.475
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.472
meiotic nuclear envelope disassembly GO:0051078 2 0.464
cell fate specification GO:0001708 71 0.463
compound eye photoreceptor cell differentiation GO:0001751 140 0.462
heart field specification GO:0003128 0 0.462
regulation of apoptotic process GO:0042981 130 0.459
Human Mouse
regulation of cell death GO:0010941 173 0.459
Human Mouse
establishment of protein localization GO:0045184 163 0.454
Human
dorsal appendage formation GO:0046843 47 0.454
mesenchymal cell differentiation GO:0048762 1 0.454
Human
male meiosis GO:0007140 52 0.451
anterior posterior axis specification embryo GO:0008595 103 0.450
establishment of mitotic spindle localization GO:0040001 17 0.443
carbohydrate derivative catabolic process GO:1901136 118 0.440
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.435
salivary gland development GO:0007431 162 0.433
striated muscle cell differentiation GO:0051146 90 0.432
salivary gland morphogenesis GO:0007435 145 0.430
embryonic axis specification GO:0000578 107 0.427
Zebrafish Mouse
regulation of axonogenesis GO:0050770 32 0.423
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.422
regulation of cardioblast differentiation GO:0051890 9 0.414
purine nucleoside triphosphate catabolic process GO:0009146 108 0.409
regulation of multicellular organism growth GO:0040014 40 0.407
purine ribonucleoside catabolic process GO:0046130 112 0.406
secondary metabolic process GO:0019748 75 0.406
aging GO:0007568 143 0.404
eye photoreceptor cell differentiation GO:0001754 145 0.403
positive regulation of proteolysis GO:0045862 52 0.401
protein localization GO:0008104 284 0.397
purine ribonucleoside metabolic process GO:0046128 127 0.393
microtubule organizing center organization GO:0031023 168 0.392
Human
regulation of centriole centriole cohesion GO:0030997 1 0.391
Human
cardiac cell fate commitment GO:0060911 17 0.390
ribonucleoside catabolic process GO:0042454 112 0.390
vesicle mediated transport GO:0016192 381 0.389
Mouse Worm
compound eye morphogenesis GO:0001745 249 0.387
eggshell formation GO:0030703 105 0.386
development of primary sexual characteristics GO:0045137 50 0.382
Worm
compound eye development GO:0048749 307 0.382
nucleoside triphosphate catabolic process GO:0009143 108 0.380
epithelial cell cell adhesion GO:0090136 6 0.376
programmed cell death GO:0012501 257 0.376
endodermal cell differentiation GO:0035987 3 0.373
Mouse Worm
cell fate determination GO:0001709 91 0.369
negative regulation of gene expression GO:0010629 387 0.367
Human Mouse
chorion containing eggshell formation GO:0007304 105 0.366
cell junction organization GO:0034330 57 0.363
determination of left right symmetry GO:0007368 9 0.363
tripartite regional subdivision GO:0007351 103 0.361
oviposition GO:0018991 19 0.357
Worm
positive regulation of developmental growth GO:0048639 62 0.355
oocyte fate commitment GO:0048600 2 0.354
regulation of eye pigmentation GO:0048073 7 0.352
chromosome segregation GO:0007059 157 0.343
Human Mouse
growth GO:0040007 359 0.343
cell activation GO:0001775 9 0.341
Mouse
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.340
ribose phosphate metabolic process GO:0019693 145 0.329
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.325
nucleoside triphosphate metabolic process GO:0009141 120 0.322
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.322
regulation of molecular function GO:0065009 217 0.321
Human Mouse Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.321
dendrite development GO:0016358 204 0.314
regulation of neurogenesis GO:0050767 158 0.302
Mouse
regulation of glial cell differentiation GO:0045685 1 0.299
Mouse
establishment of localization in cell GO:0051649 402 0.298
Human Mouse
positive regulation of phosphorylation GO:0042327 87 0.297
Mouse Worm
chemotaxis GO:0006935 249 0.294
organophosphate metabolic process GO:0019637 195 0.289
meiotic spindle checkpoint GO:0044779 1 0.287
camera type eye development GO:0043010 4 0.286
Mouse
neuronal action potential GO:0019228 10 0.282
developmental induction GO:0031128 3 0.271
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.270
cell death GO:0008219 279 0.269
gland development GO:0048732 191 0.269
Zebrafish Mouse
positive regulation of cell differentiation GO:0045597 64 0.266
Human Mouse
myotube differentiation GO:0014902 46 0.266
cardiac cell fate specification GO:0060912 10 0.265
dendrite morphogenesis GO:0048813 199 0.261
compound eye retinal cell programmed cell death GO:0046667 23 0.259
asymmetric protein localization GO:0008105 33 0.258
Worm
tissue migration GO:0090130 155 0.256
regulation of programmed cell death GO:0043067 152 0.253
Human Mouse
regulation of cell cycle GO:0051726 291 0.253
Human Mouse
endocytosis GO:0006897 310 0.251
Worm
glycosyl compound metabolic process GO:1901657 127 0.248
positive regulation of multicellular organism growth GO:0040018 21 0.247
cellular macromolecule localization GO:0070727 220 0.244
receptor mediated endocytosis GO:0006898 21 0.243
Worm
axon guidance GO:0007411 233 0.241
regeneration GO:0031099 16 0.240
nucleoside catabolic process GO:0009164 112 0.240
negative regulation of phosphate metabolic process GO:0045936 45 0.240
regulation of neuron differentiation GO:0045664 103 0.239
organonitrogen compound catabolic process GO:1901565 128 0.239
positive regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0090282 1 0.238
phosphorylation GO:0016310 294 0.237
Mouse Worm
photoreceptor cell development GO:0042461 96 0.234
synaptic growth at neuromuscular junction GO:0051124 119 0.229
establishment of spindle orientation GO:0051294 18 0.228
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.228
embryonic hemopoiesis GO:0035162 26 0.225
olfactory behavior GO:0042048 97 0.223
purine containing compound catabolic process GO:0072523 112 0.223
specification of segmental identity antennal segment GO:0007383 2 0.222
ribonucleoside metabolic process GO:0009119 127 0.221
wound healing GO:0042060 75 0.219
regulation of protein complex assembly GO:0043254 42 0.219
protein import into nucleus GO:0006606 51 0.219
Human
cell substrate adhesion GO:0031589 10 0.218
Mouse
cardioblast cell fate specification GO:0042685 9 0.212
cellular component assembly involved in morphogenesis GO:0010927 151 0.212
positive regulation of cell cycle process GO:0090068 28 0.211
regulation of protein serine threonine kinase activity GO:0071900 25 0.207
regulation of cell fate commitment GO:0010453 29 0.205
negative regulation of dna templated transcription initiation GO:2000143 1 0.204
purine ribonucleotide metabolic process GO:0009150 145 0.203
establishment of mitotic spindle orientation GO:0000132 13 0.203
cellular protein modification process GO:0006464 438 0.201
Human Worm
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.200
meiotic cell cycle process GO:1903046 132 0.200
positive regulation of organelle organization GO:0010638 65 0.198
oocyte anterior posterior axis specification GO:0007314 72 0.198
cellular response to dna damage stimulus GO:0006974 223 0.197
response to organic substance GO:0010033 284 0.195
Human Mouse
epidermal cell differentiation GO:0009913 51 0.194
response to alcohol GO:0097305 95 0.194
Human
dna templated transcriptional start site selection GO:0001173 1 0.194
epithelium migration GO:0090132 148 0.193
negative regulation of signaling GO:0023057 219 0.192
protein modification process GO:0036211 438 0.192
Human Worm
protein localization to organelle GO:0033365 82 0.191
Human
regulation of proteolysis GO:0030162 87 0.189
actin filament bundle assembly GO:0051017 26 0.185
cardiocyte differentiation GO:0035051 29 0.183
stem cell differentiation GO:0048863 117 0.183
epithelial cell development GO:0002064 274 0.183
Mouse
regulation of wound healing GO:0061041 13 0.181
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.181
negative regulation of epithelial cell migration GO:0010633 1 0.180
nucleotide metabolic process GO:0009117 161 0.179
ribonucleotide catabolic process GO:0009261 109 0.178
cellular catabolic process GO:0044248 372 0.178
negative regulation of phosphorus metabolic process GO:0010563 45 0.178
purine nucleoside metabolic process GO:0042278 127 0.176
regulation of ran gtpase activity GO:0032316 1 0.174
mesoderm development GO:0007498 78 0.174
regulation of hemocyte differentiation GO:0045610 22 0.169
regulation of embryonic development GO:0045995 68 0.169
Mouse Worm
nephron development GO:0072006 3 0.168
Mouse
response to red light GO:0010114 2 0.164
glycosyl compound catabolic process GO:1901658 112 0.163
endoderm formation GO:0001706 3 0.161
Mouse Worm
ovarian nurse cell to oocyte transport GO:0007300 27 0.159
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 1 0.157
mitotic nuclear division GO:0007067 213 0.155
oxoacid metabolic process GO:0043436 103 0.154
Human
exocytosis GO:0006887 28 0.154
regulation of mapk cascade GO:0043408 92 0.154
Mouse
positive regulation of protein transport GO:0051222 37 0.154
Human
germ cell migration GO:0008354 43 0.154
establishment of spindle localization GO:0051293 22 0.151
pole plasm assembly GO:0007315 61 0.149
single organism nuclear import GO:1902593 51 0.148
Human
pole plasm oskar mrna localization GO:0045451 46 0.147
negative regulation of mrna 3 end processing GO:0031441 3 0.146
regulation of cellular component size GO:0032535 98 0.145
purine containing compound metabolic process GO:0072521 155 0.144
epithelial cell morphogenesis GO:0003382 25 0.143
Mouse
cell type specific apoptotic process GO:0097285 38 0.143
regulation of actin filament based process GO:0032970 42 0.143
Human Worm
regulation of response to stress GO:0080134 200 0.139
dephosphorylation GO:0016311 51 0.139
guanosine containing compound catabolic process GO:1901069 74 0.137
release of cytoplasmic sequestered nf kappab GO:0008588 1 0.137
malpighian tubule development GO:0072002 64 0.136
actin filament organization GO:0007015 126 0.134
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.134
Mouse
positive regulation of response to stimulus GO:0048584 323 0.133
Mouse
regulation of embryonic cell shape GO:0016476 30 0.133
purine nucleotide catabolic process GO:0006195 109 0.132
stem cell division GO:0017145 69 0.132
cellular response to chemical stimulus GO:0070887 199 0.132
Human Mouse
regulation of cell proliferation GO:0042127 163 0.131
Human Mouse
wnt signaling pathway involved in heart development GO:0003306 3 0.131
regulation of cell cycle process GO:0010564 181 0.131
Human Mouse
negative regulation of developmental process GO:0051093 201 0.130
germarium derived oocyte differentiation GO:0030706 29 0.129
dna integration GO:0015074 1 0.129
maintenance of location in cell GO:0051651 28 0.129
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.128
meiotic dna repair synthesis GO:0000711 3 0.128
negative regulation of apoptotic signaling pathway GO:2001234 5 0.128
Mouse
fusion cell fate specification GO:0035156 4 0.127
regulation of actin cytoskeleton organization GO:0032956 42 0.126
Worm
regulation of protein localization GO:0032880 76 0.126
Human Worm
endodermal cell fate commitment GO:0001711 3 0.126
Mouse Worm
organelle assembly GO:0070925 198 0.125
single organismal cell cell adhesion GO:0016337 45 0.123
sensory perception of mechanical stimulus GO:0050954 72 0.121
ribonucleoside triphosphate metabolic process GO:0009199 119 0.121
exocrine system development GO:0035272 162 0.121
retinal cell programmed cell death GO:0046666 25 0.121
regulation of cellular catabolic process GO:0031329 157 0.120
nucleoside phosphate catabolic process GO:1901292 110 0.118
cellular protein complex assembly GO:0043623 71 0.118
epithelial cell type specification open tracheal system GO:0035153 11 0.118
vesicle localization GO:0051648 55 0.118
Mouse
regulation of cellular response to stress GO:0080135 89 0.118
muscle organ development GO:0007517 127 0.117
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.117
organophosphate catabolic process GO:0046434 112 0.116
positive regulation of phosphorus metabolic process GO:0010562 139 0.114
Mouse Worm
cell morphogenesis involved in malpighian tubule morphogenesis GO:0061336 1 0.113
protein import GO:0017038 55 0.112
Human
cardiac muscle tissue development GO:0048738 9 0.112
specification of symmetry GO:0009799 13 0.112
Zebrafish Mouse
regulation of cell differentiation GO:0045595 302 0.111
leaf development GO:0048366 3 0.111
hindbrain development GO:0030902 2 0.110
centripetally migrating follicle cell migration GO:0060269 1 0.110
stem cell maintenance GO:0019827 67 0.110
ganglion mother cell fate determination GO:0007402 2 0.109
nucleoside metabolic process GO:0009116 127 0.109
p granule organization GO:0030719 4 0.109
regulation of phosphorylation GO:0042325 147 0.108
Mouse Worm
positive regulation of cell death GO:0010942 69 0.107
Human
regulation of intracellular protein transport GO:0033157 46 0.106
Human
endoderm development GO:0007492 6 0.106
Mouse Worm
regulation of protein catabolic process GO:0042176 55 0.106
neuron projection guidance GO:0097485 241 0.106
negative regulation of wnt signaling pathway GO:0030178 28 0.106
Zebrafish
segment polarity determination GO:0007367 25 0.105
positive regulation of chromatin silencing at telomere GO:0031940 2 0.103
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051436 2 0.102
cell cell junction assembly GO:0007043 38 0.102
regulation of hematopoietic stem cell differentiation GO:1902036 1 0.102
gtp catabolic process GO:0006184 72 0.102
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.100
synaptic vesicle budding from presynaptic membrane GO:0016185 1 0.099
regulation of centriole replication GO:0046599 2 0.098
positive regulation of phosphate metabolic process GO:0045937 139 0.098
Mouse Worm
female meiotic division GO:0007143 70 0.097
anterior posterior axis specification follicular epithelium GO:0030714 2 0.096
spindle localization GO:0051653 22 0.095
dorsal closure leading edge cell differentiation GO:0046663 2 0.095
regulation of cellular localization GO:0060341 136 0.095
Human
head development GO:0060322 135 0.095
Mouse
gastrulation involving germ band extension GO:0010004 36 0.094
meiotic sister chromatid cohesion centromeric GO:0051754 2 0.091
positive regulation of cell maturation GO:1903431 2 0.091
negative regulation of protein phosphorylation GO:0001933 17 0.091
centrosome cycle GO:0007098 137 0.090
Human
regulation of jnk cascade GO:0046328 40 0.090
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.090
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.090
response to ketone GO:1901654 34 0.089
positive regulation of intracellular protein transport GO:0090316 30 0.089
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.088

arm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.880
Human
nervous system disease DOID:863 0 0.678
reproductive organ cancer DOID:193 0 0.523
Human
ovarian cancer DOID:2394 0 0.523
Human
female reproductive organ cancer DOID:120 0 0.523
Human
cancer DOID:162 0 0.523
Human
disease of cellular proliferation DOID:14566 0 0.523
Human
organ system cancer DOID:0050686 0 0.523
Human
musculoskeletal system disease DOID:17 0 0.507
Human
large intestine cancer DOID:5672 0 0.338
Human
gastrointestinal system cancer DOID:3119 0 0.338
Human
intestinal cancer DOID:10155 0 0.338
Human
colorectal cancer DOID:9256 0 0.338
Human
endocrine gland cancer DOID:170 0 0.291
thyroid cancer DOID:1781 0 0.291
hajdu cheney syndrome DOID:2736 0 0.177
artery disease DOID:0050828 0 0.164
vascular disease DOID:178 0 0.164
cardiovascular system disease DOID:1287 0 0.164
Human
aortic disease DOID:520 0 0.164
organ system benign neoplasm DOID:0060085 0 0.152
Human
pilomatrixoma DOID:5374 0 0.152
Human
hair follicle neoplasm DOID:5375 0 0.152
Human
benign neoplasm DOID:0060072 0 0.152
Human
skin benign neoplasm DOID:3165 0 0.152
Human
integumentary system benign neoplasm DOID:0060121 0 0.152
Human
costello syndrome DOID:0050469 0 0.123
disease of metabolism DOID:0014667 0 0.119
hemochromatosis DOID:2352 0 0.119
inherited metabolic disorder DOID:655 0 0.119
metal metabolism disorder DOID:896 0 0.119
hepatobiliary disease DOID:3118 0 0.114
gastrointestinal system disease DOID:77 0 0.114
liver disease DOID:409 0 0.114
alagille syndrome DOID:9245 0 0.114
myopathy DOID:423 0 0.113
Human
muscular disease DOID:0080000 0 0.113
Human
heart disease DOID:114 0 0.113
Human
cardiomyopathy DOID:0050700 0 0.113
Human
intrinsic cardiomyopathy DOID:0060036 0 0.113
Human
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.113
Human
muscle tissue disease DOID:66 0 0.113
Human
nervous system benign neoplasm DOID:0060115 0 0.106
neuroma DOID:2001 0 0.106
neurilemmoma DOID:3192 0 0.106
neurilemmomatosis DOID:3204 0 0.106
heart valve disease DOID:4079 0 0.093