Drosophila melanogaster

0 known processes

skpF (Dmel_CG12227)

CG12227 gene product from transcript CG12227-RA

(Aliases: CG12227,Dmel\CG12227,Skp)

skpF biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of developmental process GO:0051093 201 0.349
positive regulation of macromolecule metabolic process GO:0010604 405 0.173
dna metabolic process GO:0006259 227 0.160
intracellular signal transduction GO:0035556 300 0.135
chromatin organization GO:0006325 207 0.104
regulation of multicellular organismal development GO:2000026 414 0.102
cell cycle checkpoint GO:0000075 95 0.087
negative regulation of rna biosynthetic process GO:1902679 240 0.083
regulation of protein metabolic process GO:0051246 256 0.078
cellular response to dna damage stimulus GO:0006974 223 0.077
regulation of phosphorylation GO:0042325 147 0.076
positive regulation of protein metabolic process GO:0051247 128 0.075
regulation of cell death GO:0010941 173 0.072
regulation of cell cycle phase transition GO:1901987 130 0.071
regulation of cellular component biogenesis GO:0044087 201 0.070
regulation of synapse structure and activity GO:0050803 128 0.070
negative regulation of response to stimulus GO:0048585 258 0.066
cellular macromolecule localization GO:0070727 220 0.066
dna integrity checkpoint GO:0031570 81 0.065
chromosome organization GO:0051276 360 0.062
cellular protein modification process GO:0006464 438 0.056
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.055
protein modification process GO:0036211 438 0.055
chromatin modification GO:0016568 147 0.055
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.054
dna packaging GO:0006323 91 0.052
phosphorylation GO:0016310 294 0.052
regulation of cell cycle GO:0051726 291 0.051
negative regulation of multicellular organismal process GO:0051241 142 0.048
positive regulation of cellular protein metabolic process GO:0032270 118 0.048
regulation of cell differentiation GO:0045595 302 0.047
negative regulation of biosynthetic process GO:0009890 277 0.047
negative regulation of cell cycle process GO:0010948 109 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.045
defense response to other organism GO:0098542 225 0.045
apoptotic process GO:0006915 159 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.043
endocytosis GO:0006897 310 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
positive regulation of signaling GO:0023056 243 0.041
centrosome organization GO:0051297 163 0.041
positive regulation of proteolysis GO:0045862 52 0.040
proteasomal protein catabolic process GO:0010498 59 0.039
cell death GO:0008219 279 0.039
negative regulation of cellular biosynthetic process GO:0031327 277 0.038
proteolysis GO:0006508 192 0.038
cellular catabolic process GO:0044248 372 0.038
positive regulation of cell communication GO:0010647 250 0.037
regulation of cysteine type endopeptidase activity GO:2000116 27 0.037
vesicle mediated transport GO:0016192 381 0.037
negative regulation of signaling GO:0023057 219 0.036
mitotic cell cycle phase transition GO:0044772 138 0.036
negative regulation of cell differentiation GO:0045596 143 0.036
macromolecular complex assembly GO:0065003 256 0.036
negative regulation of cellular component organization GO:0051129 108 0.036
death GO:0016265 284 0.036
organic substance catabolic process GO:1901575 308 0.034
centrosome duplication GO:0051298 121 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.034
microtubule organizing center organization GO:0031023 168 0.034
organic substance transport GO:0071702 257 0.034
reproductive behavior GO:0019098 122 0.034
single organism biosynthetic process GO:0044711 206 0.033
regulation of phosphorus metabolic process GO:0051174 210 0.032
protein localization GO:0008104 284 0.032
body morphogenesis GO:0010171 2 0.032
phagocytosis GO:0006909 215 0.032
positive regulation of hydrolase activity GO:0051345 78 0.031
negative regulation of rna metabolic process GO:0051253 251 0.031
negative regulation of cell communication GO:0010648 223 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.030
axonogenesis GO:0007409 290 0.030
multi organism reproductive behavior GO:0044705 121 0.030
regulation of apoptotic process GO:0042981 130 0.030
negative regulation of signal transduction GO:0009968 206 0.029
modification dependent protein catabolic process GO:0019941 78 0.029
establishment of localization in cell GO:0051649 402 0.029
growth GO:0040007 359 0.028
mitotic nuclear division GO:0007067 213 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
programmed cell death GO:0012501 257 0.027
regulation of proteolysis GO:0030162 87 0.027
positive regulation of molecular function GO:0044093 136 0.027
intracellular transport GO:0046907 228 0.027
negative regulation of programmed cell death GO:0043069 72 0.027
covalent chromatin modification GO:0016569 106 0.027
dna damage checkpoint GO:0000077 78 0.027
regulation of phosphate metabolic process GO:0019220 210 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
cell cycle phase transition GO:0044770 140 0.026
regulation of catalytic activity GO:0050790 185 0.026
neuromuscular junction development GO:0007528 149 0.026
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
developmental maturation GO:0021700 172 0.026
catabolic process GO:0009056 409 0.026
negative regulation of gene expression GO:0010629 387 0.025
regulation of molecular function GO:0065009 217 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
axon development GO:0061564 297 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
chromosome condensation GO:0030261 41 0.024
multi organism behavior GO:0051705 175 0.024
aging GO:0007568 143 0.024
single organism cellular localization GO:1902580 180 0.024
tissue morphogenesis GO:0048729 297 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
protein complex biogenesis GO:0070271 201 0.023
stem cell differentiation GO:0048863 117 0.022
nuclear division GO:0000280 332 0.022
regulation of programmed cell death GO:0043067 152 0.022
developmental growth GO:0048589 280 0.022
regulation of mitotic cell cycle GO:0007346 190 0.021
regulation of jnk cascade GO:0046328 40 0.021
intracellular protein transport GO:0006886 104 0.021
mrna metabolic process GO:0016071 124 0.021
negative regulation of cell death GO:0060548 81 0.021
dna conformation change GO:0071103 105 0.021
positive regulation of programmed cell death GO:0043068 62 0.021
ras protein signal transduction GO:0007265 88 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
cell growth GO:0016049 108 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
defense response to bacterium GO:0042742 178 0.020
negative regulation of cell cycle GO:0045786 116 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.020
mitotic cell cycle checkpoint GO:0007093 88 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
regulation of developmental growth GO:0048638 174 0.020
regulation of mapk cascade GO:0043408 92 0.019
regulation of cell cycle process GO:0010564 181 0.019
regulation of immune system process GO:0002682 176 0.019
positive regulation of signal transduction GO:0009967 223 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
regulation of organelle organization GO:0033043 196 0.019
regulation of response to stress GO:0080134 200 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.018
regulation of mrna processing GO:0050684 71 0.018
cell maturation GO:0048469 144 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
negative regulation of apoptotic process GO:0043066 63 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
histone modification GO:0016570 106 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
protein transport GO:0015031 155 0.018
negative regulation of growth GO:0045926 84 0.018
rna processing GO:0006396 147 0.017
protein complex assembly GO:0006461 200 0.017
macromolecule catabolic process GO:0009057 161 0.017
single organism intracellular transport GO:1902582 207 0.017
protein targeting GO:0006605 64 0.017
negative regulation of developmental growth GO:0048640 64 0.017
olfactory behavior GO:0042048 97 0.017
regulation of mrna metabolic process GO:1903311 72 0.017
single organism behavior GO:0044708 391 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
positive regulation of endopeptidase activity GO:0010950 26 0.017
positive regulation of gene expression GO:0010628 290 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.016
response to other organism GO:0051707 293 0.016
regulation of endopeptidase activity GO:0052548 36 0.016
muscle cell development GO:0055001 50 0.016
response to oxygen containing compound GO:1901700 200 0.016
regulation of hydrolase activity GO:0051336 97 0.016
regulation of protein stability GO:0031647 43 0.016
jak stat cascade GO:0007259 49 0.016
cellular protein localization GO:0034613 160 0.016
regulation of nervous system development GO:0051960 248 0.016
negative regulation of phosphate metabolic process GO:0045936 45 0.016
protein localization to organelle GO:0033365 82 0.016
regulation of microtubule cytoskeleton organization GO:0070507 41 0.016
cytoplasmic transport GO:0016482 130 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
cellular protein catabolic process GO:0044257 83 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
segmentation GO:0035282 207 0.015
regulation of microtubule based process GO:0032886 49 0.015
appendage development GO:0048736 401 0.015
regulation of cellular localization GO:0060341 136 0.015
stem cell development GO:0048864 79 0.015
flight behavior GO:0007629 26 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
actin cytoskeleton organization GO:0030036 206 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
regulation of peptidase activity GO:0052547 39 0.015
regulation of localization GO:0032879 275 0.015
g2 dna damage checkpoint GO:0031572 69 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.015
regulation of protein modification process GO:0031399 112 0.015
taxis GO:0042330 304 0.014
regulation of transport GO:0051049 181 0.014
response to oxidative stress GO:0006979 86 0.014
mrna splicing via spliceosome GO:0000398 73 0.014
regulation of rna splicing GO:0043484 69 0.014
establishment of protein localization GO:0045184 163 0.014
muscle organ development GO:0007517 127 0.014
small molecule metabolic process GO:0044281 305 0.014
protein catabolic process GO:0030163 101 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
organelle fission GO:0048285 340 0.014
developmental cell growth GO:0048588 52 0.014
gene silencing GO:0016458 138 0.013
cell aging GO:0007569 2 0.013
adult locomotory behavior GO:0008344 76 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
determination of adult lifespan GO:0008340 137 0.013
regulation of growth GO:0040008 233 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
secretion by cell GO:0032940 101 0.013
regulation of cellular response to stress GO:0080135 89 0.013
stress activated mapk cascade GO:0051403 52 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
cell division GO:0051301 248 0.013
response to external biotic stimulus GO:0043207 293 0.013
cell proliferation GO:0008283 299 0.013
organelle assembly GO:0070925 198 0.013
nitrogen compound transport GO:0071705 85 0.013
negative regulation of nervous system development GO:0051961 92 0.013
response to biotic stimulus GO:0009607 294 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
cell motility GO:0048870 251 0.012
positive regulation of developmental process GO:0051094 143 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
regulation of response to external stimulus GO:0032101 115 0.012
respiratory system development GO:0060541 213 0.012
negative regulation of cell development GO:0010721 62 0.012
localization of cell GO:0051674 257 0.012
response to abiotic stimulus GO:0009628 341 0.012
mapk cascade GO:0000165 107 0.012
nucleotide metabolic process GO:0009117 161 0.012
actin filament based process GO:0030029 220 0.012
cytokinesis GO:0000910 90 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
oxoacid metabolic process GO:0043436 103 0.012
germ cell migration GO:0008354 43 0.012
positive regulation of cell death GO:0010942 69 0.012
negative regulation of phosphorus metabolic process GO:0010563 45 0.012
adult behavior GO:0030534 137 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of synapse organization GO:0050807 110 0.011
nuclear transport GO:0051169 72 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
multicellular organismal aging GO:0010259 140 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
immune system process GO:0002376 347 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
rna splicing GO:0008380 83 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
positive regulation of mitotic cell cycle GO:0045931 34 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
regulation of cell proliferation GO:0042127 163 0.011
mitotic dna damage checkpoint GO:0044773 74 0.011
protein maturation GO:0051604 71 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
response to reactive oxygen species GO:0000302 24 0.011
retina development in camera type eye GO:0060041 4 0.011
chemosensory behavior GO:0007635 106 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
appendage morphogenesis GO:0035107 397 0.011
notch signaling pathway GO:0007219 120 0.010
positive regulation of cell cycle GO:0045787 43 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
positive regulation of protein modification process GO:0031401 58 0.010
stem cell maintenance GO:0019827 67 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
protein localization to nucleus GO:0034504 55 0.010
protein phosphorylation GO:0006468 169 0.010
meiotic cell cycle GO:0051321 171 0.010

skpF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.012