Drosophila melanogaster

146 known processes

Dsp1 (Dmel_CG12223)

Dorsal switch protein 1

(Aliases: Dmel\CG12223,ssrp2,Ssrp2,DSP1,dsp1,CG12223,Hmg14D)

Dsp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell death GO:0008219 279 0.890
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.861
negative regulation of rna metabolic process GO:0051253 251 0.857
positive regulation of rna biosynthetic process GO:1902680 266 0.838
Worm
protein modification process GO:0036211 438 0.781
apoptotic process GO:0006915 159 0.774
regulation of response to stress GO:0080134 200 0.769
photoreceptor cell differentiation GO:0046530 170 0.733
eye morphogenesis GO:0048592 260 0.689
response to other organism GO:0051707 293 0.558
central nervous system development GO:0007417 201 0.543
regulation of multicellular organismal development GO:2000026 414 0.542
Worm
neurological system process GO:0050877 358 0.537
ion transport GO:0006811 145 0.528
positive regulation of biosynthetic process GO:0009891 316 0.517
Worm
negative regulation of biosynthetic process GO:0009890 277 0.508
developmental growth GO:0048589 280 0.503
Worm
programmed cell death GO:0012501 257 0.476
regulation of molecular function GO:0065009 217 0.459
regulation of protein metabolic process GO:0051246 256 0.454
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.454
Worm
regulation of phosphorus metabolic process GO:0051174 210 0.444
negative regulation of rna biosynthetic process GO:1902679 240 0.443
positive regulation of gene expression GO:0010628 290 0.436
Worm
wnt signaling pathway GO:0016055 98 0.429
Worm
epithelial cell differentiation GO:0030855 322 0.424
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.421
regulation of cell death GO:0010941 173 0.403
positive regulation of cell differentiation GO:0045597 64 0.396
positive regulation of nucleic acid templated transcription GO:1903508 266 0.384
Worm
chromatin mediated maintenance of transcription GO:0048096 7 0.372
organelle fission GO:0048285 340 0.366
Worm
transcription from rna polymerase ii promoter GO:0006366 368 0.361
regulation of transport GO:0051049 181 0.358
regulation of cellular protein metabolic process GO:0032268 243 0.355
regulation of localization GO:0032879 275 0.351
negative regulation of gene expression GO:0010629 387 0.342
axon development GO:0061564 297 0.335
carbohydrate derivative metabolic process GO:1901135 217 0.334
positive regulation of macromolecule metabolic process GO:0010604 405 0.324
Worm
neuron projection guidance GO:0097485 241 0.311
establishment of protein localization GO:0045184 163 0.309
protein phosphorylation GO:0006468 169 0.302
actin cytoskeleton organization GO:0030036 206 0.284
intracellular transport GO:0046907 228 0.276
axonogenesis GO:0007409 290 0.269
endocytosis GO:0006897 310 0.258
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.247
embryo development ending in birth or egg hatching GO:0009792 152 0.242
Worm
sensory organ morphogenesis GO:0090596 260 0.241
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.235
regulation of cell differentiation GO:0045595 302 0.230
male gamete generation GO:0048232 201 0.229
regulation of cellular response to stress GO:0080135 89 0.228
positive regulation of protein metabolic process GO:0051247 128 0.226
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.221
response to oxygen containing compound GO:1901700 200 0.215
cell adhesion GO:0007155 136 0.215
positive regulation of transcription dna templated GO:0045893 266 0.213
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.209
Worm
positive regulation of response to stimulus GO:0048584 323 0.204
response to organic substance GO:0010033 284 0.203
vesicle mediated transport GO:0016192 381 0.202
Worm
phosphorylation GO:0016310 294 0.201
muscle structure development GO:0061061 224 0.193
intracellular signal transduction GO:0035556 300 0.192
positive regulation of developmental process GO:0051094 143 0.191
Worm
cellular response to chemical stimulus GO:0070887 199 0.187
locomotory behavior GO:0007626 176 0.185
regulation of cellular ketone metabolic process GO:0010565 3 0.184
regulation of programmed cell death GO:0043067 152 0.180
death GO:0016265 284 0.168
biological adhesion GO:0022610 138 0.165
positive regulation of transport GO:0051050 92 0.165
regulation of organelle organization GO:0033043 196 0.164
regulation of immune system process GO:0002682 176 0.156
cellular response to radiation GO:0071478 52 0.151
positive regulation of cellular component organization GO:0051130 156 0.150
organic substance transport GO:0071702 257 0.150
defense response GO:0006952 300 0.147
regulation of immune response GO:0050776 118 0.147
regulation of system process GO:0044057 36 0.145
signal transduction by phosphorylation GO:0023014 107 0.144
salivary gland morphogenesis GO:0007435 145 0.141
negative regulation of signal transduction GO:0009968 206 0.140
macromolecular complex assembly GO:0065003 256 0.133
establishment of localization in cell GO:0051649 402 0.133
regulation of phosphorylation GO:0042325 147 0.131
negative regulation of developmental process GO:0051093 201 0.130
Worm
positive regulation of cell communication GO:0010647 250 0.130
negative regulation of cell differentiation GO:0045596 143 0.125
positive regulation of multicellular organismal process GO:0051240 143 0.123
Worm
cellular response to oxygen containing compound GO:1901701 79 0.122
cell motility GO:0048870 251 0.121
cellular protein modification process GO:0006464 438 0.120
regulation of cell proliferation GO:0042127 163 0.118
mrna metabolic process GO:0016071 124 0.116
protein complex biogenesis GO:0070271 201 0.114
negative regulation of cellular metabolic process GO:0031324 382 0.113
eye development GO:0001654 323 0.112
positive regulation of cellular biosynthetic process GO:0031328 316 0.112
Worm
chromatin organization GO:0006325 207 0.111
spermatogenesis GO:0007283 200 0.111
immune system process GO:0002376 347 0.109
response to organic cyclic compound GO:0014070 89 0.107
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.105
Worm
gene silencing GO:0016458 138 0.105
regulation of cellular localization GO:0060341 136 0.105
regulation of neurogenesis GO:0050767 158 0.102
response to alcohol GO:0097305 95 0.101
cellular component assembly involved in morphogenesis GO:0010927 151 0.099
blood circulation GO:0008015 26 0.098
mapk cascade GO:0000165 107 0.097
cellular catabolic process GO:0044248 372 0.097
cell migration GO:0016477 238 0.097
mitotic cell cycle embryonic GO:0045448 38 0.096
protein complex assembly GO:0006461 200 0.095
chemotaxis GO:0006935 249 0.094
regulation of phosphate metabolic process GO:0019220 210 0.091
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.086
positive regulation of signal transduction GO:0009967 223 0.085
epithelial cell migration GO:0010631 148 0.085
phagocytosis GO:0006909 215 0.084
chromosome organization GO:0051276 360 0.080
cellular response to abiotic stimulus GO:0071214 58 0.080
positive regulation of phosphate metabolic process GO:0045937 139 0.077
negative regulation of cellular biosynthetic process GO:0031327 277 0.077
negative regulation of cell communication GO:0010648 223 0.076
positive regulation of cell motility GO:2000147 3 0.073
positive regulation of immune response GO:0050778 63 0.073
epithelial cell development GO:0002064 274 0.072
negative regulation of cellular protein metabolic process GO:0032269 85 0.071
immune response regulating signaling pathway GO:0002764 2 0.071
negative regulation of phosphorylation GO:0042326 35 0.069
negative regulation of phosphatase activity GO:0010923 3 0.069
skin development GO:0043588 65 0.069
development of primary sexual characteristics GO:0045137 50 0.067
Worm
neuromuscular process GO:0050905 21 0.067
imaginal disc derived wing morphogenesis GO:0007476 337 0.066
immune response GO:0006955 246 0.066
compound eye development GO:0048749 307 0.065
exocrine system development GO:0035272 162 0.065
negative regulation of molecular function GO:0044092 51 0.065
negative regulation of nucleotide catabolic process GO:0030812 1 0.064
regulation of protein modification process GO:0031399 112 0.063
defense response to other organism GO:0098542 225 0.063
learning or memory GO:0007611 141 0.062
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.060
peptidyl amino acid modification GO:0018193 105 0.060
regulation of gene expression epigenetic GO:0040029 128 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.060
negative regulation of protein metabolic process GO:0051248 85 0.059
g protein coupled receptor signaling pathway GO:0007186 136 0.058
morphogenesis of embryonic epithelium GO:0016331 94 0.057
enzyme linked receptor protein signaling pathway GO:0007167 179 0.057
response to bacterium GO:0009617 198 0.056
regulation of mapk cascade GO:0043408 92 0.055
dendrite development GO:0016358 204 0.055
larval development GO:0002164 104 0.055
Worm
positive regulation of signaling GO:0023056 243 0.055
regulation of stress activated mapk cascade GO:0032872 41 0.053
stem cell differentiation GO:0048863 117 0.053
positive regulation of immune system process GO:0002684 68 0.053
immune system development GO:0002520 57 0.053
regulation of protein localization GO:0032880 76 0.052
epidermis development GO:0008544 65 0.051
positive regulation of cellular protein metabolic process GO:0032270 118 0.051
purine ribonucleoside metabolic process GO:0046128 127 0.050
regulation of intracellular signal transduction GO:1902531 236 0.050
response to external biotic stimulus GO:0043207 293 0.050
regulation of cell cycle GO:0051726 291 0.049
response to wounding GO:0009611 94 0.049
circadian behavior GO:0048512 76 0.048
hemopoiesis GO:0030097 46 0.048
autophagy GO:0006914 108 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
protein transport GO:0015031 155 0.047
cell division GO:0051301 248 0.046
negative regulation of transcription dna templated GO:0045892 237 0.046
regulation of cell cycle process GO:0010564 181 0.045
single organism biosynthetic process GO:0044711 206 0.045
axon guidance GO:0007411 233 0.045
gland morphogenesis GO:0022612 145 0.045
compound eye photoreceptor cell differentiation GO:0001751 140 0.044
regulation of kinase activity GO:0043549 53 0.044
photoreceptor cell development GO:0042461 96 0.044
regulation of cell shape GO:0008360 113 0.044
divalent inorganic cation transport GO:0072511 30 0.044
cognition GO:0050890 141 0.043
cellular response to dna damage stimulus GO:0006974 223 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.041
Worm
cellular response to organic substance GO:0071310 132 0.041
eye photoreceptor cell differentiation GO:0001754 145 0.041
cell cycle checkpoint GO:0000075 95 0.041
positive regulation of cell migration GO:0030335 2 0.041
regulation of neuron differentiation GO:0045664 103 0.040
actin filament organization GO:0007015 126 0.039
positive regulation of neurogenesis GO:0050769 41 0.039
regulation of protein transport GO:0051223 57 0.039
posttranscriptional regulation of gene expression GO:0010608 145 0.038
regulation of apoptotic process GO:0042981 130 0.038
negative regulation of signaling GO:0023057 219 0.038
reproductive structure development GO:0048608 74 0.037
Worm
developmental programmed cell death GO:0010623 138 0.037
regulation of mrna metabolic process GO:1903311 72 0.037
regulation of cell development GO:0060284 215 0.037
renal system development GO:0072001 72 0.037
segmentation GO:0035282 207 0.036
rna splicing GO:0008380 83 0.036
cellular response to endogenous stimulus GO:0071495 80 0.035
dorsal closure GO:0007391 79 0.035
response to endogenous stimulus GO:0009719 119 0.035
brain development GO:0007420 120 0.035
positive regulation of programmed cell death GO:0043068 62 0.034
cytoplasmic transport GO:0016482 130 0.034
regulation of catabolic process GO:0009894 170 0.033
regulation of intracellular transport GO:0032386 64 0.033
negative regulation of mitotic cell cycle GO:0045930 109 0.033
cell maturation GO:0048469 144 0.033
organelle inheritance GO:0048308 2 0.032
appendage morphogenesis GO:0035107 397 0.032
negative regulation of nucleoside metabolic process GO:0045978 1 0.032
positive regulation of cell cycle g2 m phase transition GO:1902751 2 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
regulation of nuclear division GO:0051783 58 0.032
dendrite morphogenesis GO:0048813 199 0.031
connective tissue development GO:0061448 3 0.031
regulation of protein kinase activity GO:0045859 51 0.031
nuclear transport GO:0051169 72 0.030
taxis GO:0042330 304 0.030
cellular amine metabolic process GO:0044106 12 0.030
nucleocytoplasmic transport GO:0006913 72 0.029
hematopoietic or lymphoid organ development GO:0048534 57 0.029
aging GO:0007568 143 0.028
positive regulation of cell development GO:0010720 61 0.028
regulation of meiosis GO:0040020 3 0.028
immune response activating signal transduction GO:0002757 2 0.027
regulation of transferase activity GO:0051338 58 0.027
homeostatic process GO:0042592 199 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
negative regulation of immune system process GO:0002683 50 0.026
positive regulation of protein modification process GO:0031401 58 0.025
cell proliferation GO:0008283 299 0.025
cellular ketone metabolic process GO:0042180 24 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.025
positive regulation of response to external stimulus GO:0032103 44 0.025
stress activated mapk cascade GO:0051403 52 0.025
rna splicing via transesterification reactions GO:0000375 73 0.025
regulation of secretion by cell GO:1903530 39 0.024
multicellular organism growth GO:0035264 46 0.024
Worm
salivary gland development GO:0007431 162 0.024
heart process GO:0003015 37 0.024
metal ion transport GO:0030001 74 0.024
stress activated protein kinase signaling cascade GO:0031098 55 0.024
regulation of hemocyte proliferation GO:0035206 37 0.024
positive regulation of catabolic process GO:0009896 105 0.023
negative regulation of cell proliferation GO:0008285 69 0.023
wound healing GO:0042060 75 0.023
protein localization GO:0008104 284 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
positive regulation of intracellular transport GO:0032388 42 0.023
tissue morphogenesis GO:0048729 297 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.022
regulation of chromatin organization GO:1902275 32 0.022
regulation of phosphatase activity GO:0010921 3 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
growth GO:0040007 359 0.022
Worm
cardiovascular system development GO:0072358 82 0.022
gland development GO:0048732 191 0.022
transmembrane transport GO:0055085 139 0.021
response to lipid GO:0033993 38 0.021
regulation of protein phosphorylation GO:0001932 64 0.021
inter male aggressive behavior GO:0002121 60 0.021
actin filament based process GO:0030029 220 0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.021
nitric oxide metabolic process GO:0046209 1 0.021
regulation of ion transport GO:0043269 39 0.020
sex differentiation GO:0007548 81 0.020
Worm
neuron recognition GO:0008038 101 0.020
camera type eye development GO:0043010 4 0.020
regulation of growth GO:0040008 233 0.020
Worm
purine nucleotide metabolic process GO:0006163 146 0.020
localization of cell GO:0051674 257 0.020
histolysis GO:0007559 102 0.020
cellular response to organic cyclic compound GO:0071407 32 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 2 0.019
head development GO:0060322 135 0.019
regulation of catalytic activity GO:0050790 185 0.019
compound eye morphogenesis GO:0001745 249 0.019
positive regulation of gene expression epigenetic GO:0045815 16 0.019
negative regulation of cell death GO:0060548 81 0.019
single organism intracellular transport GO:1902582 207 0.019
regulation of cellular component biogenesis GO:0044087 201 0.018
calcium ion transport GO:0006816 24 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
mitochondrial membrane organization GO:0007006 3 0.018
response to abiotic stimulus GO:0009628 341 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
regulation of protein import into nucleus GO:0042306 28 0.018
regulation of cell cycle phase transition GO:1901987 130 0.017
circulatory system process GO:0003013 37 0.017
dna metabolic process GO:0006259 227 0.017
germ cell migration GO:0008354 43 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
cellular response to lipid GO:0071396 20 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
regulation of chromosome organization GO:0033044 64 0.017
proteolysis GO:0006508 192 0.017
response to nutrient levels GO:0031667 114 0.017
positive regulation of ruffle assembly GO:1900029 1 0.016
regulation of cell division GO:0051302 72 0.016
regulation of nucleocytoplasmic transport GO:0046822 35 0.016
autophagic cell death GO:0048102 83 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
Worm
regulation of multi organism process GO:0043900 131 0.016
macroautophagy GO:0016236 42 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
dephosphorylation GO:0016311 51 0.015
response to drug GO:0042493 17 0.015
regulation of intracellular protein transport GO:0033157 46 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
receptor mediated endocytosis GO:0006898 21 0.015
Worm
intracellular protein transport GO:0006886 104 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
chorion containing eggshell formation GO:0007304 105 0.015
gonad development GO:0008406 50 0.015
Worm
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
jnk cascade GO:0007254 50 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
molting cycle GO:0042303 56 0.014
purine containing compound catabolic process GO:0072523 112 0.014
meiotic cell cycle GO:0051321 171 0.014
Worm
cellular divalent inorganic cation homeostasis GO:0072503 23 0.014
regulation of ruffle assembly GO:1900027 1 0.014
regulation of cytoplasmic transport GO:1903649 47 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.013
Worm
heterocycle catabolic process GO:0046700 166 0.013
regulation of cell fate commitment GO:0010453 29 0.013
regulation of nervous system development GO:0051960 248 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
regulation of proteolysis GO:0030162 87 0.013
ovarian follicle cell development GO:0030707 248 0.013
cell fate specification GO:0001708 71 0.013
Worm
organic cyclic compound catabolic process GO:1901361 168 0.012
cell cycle phase transition GO:0044770 140 0.012
maintenance of location GO:0051235 73 0.012
positive regulation of molecular function GO:0044093 136 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
camera type eye morphogenesis GO:0048593 2 0.012
regulation of protein serine threonine kinase activity GO:0071900 25 0.012
protein import GO:0017038 55 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.011
diterpenoid biosynthetic process GO:0016102 1 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
open tracheal system development GO:0007424 204 0.011
embryonic morphogenesis GO:0048598 206 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
reproductive system development GO:0061458 74 0.011
Worm
alternative mrna splicing via spliceosome GO:0000380 60 0.011
regulation of dna templated transcription in response to stress GO:0043620 4 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
regulation of gene silencing GO:0060968 63 0.010
negative regulation of protein modification process GO:0031400 29 0.010
gliogenesis GO:0042063 80 0.010
carboxylic acid metabolic process GO:0019752 92 0.010
positive regulation of proteolysis GO:0045862 52 0.010
negative regulation of phosphorus metabolic process GO:0010563 45 0.010
olfactory behavior GO:0042048 97 0.010
nucleotide catabolic process GO:0009166 109 0.010
rna processing GO:0006396 147 0.010
renal tubule morphogenesis GO:0061333 44 0.010
purine containing compound metabolic process GO:0072521 155 0.010
mrna splicing via spliceosome GO:0000398 73 0.010
salivary gland histolysis GO:0035070 88 0.010
mitotic spindle organization GO:0007052 220 0.010

Dsp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022