Drosophila melanogaster

33 known processes

Zasp66 (Dmel_CG6416)

Z band alternatively spliced PDZ-motif protein 66

(Aliases: Dmel\CG6416,anon-WO0153538.30,CG6416)

Zasp66 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myofibril assembly GO:0030239 36 0.974
actomyosin structure organization GO:0031032 56 0.974
sarcomere organization GO:0045214 26 0.949
organelle assembly GO:0070925 198 0.897
adult somatic muscle development GO:0007527 14 0.868
actin filament based process GO:0030029 220 0.817
protein complex biogenesis GO:0070271 201 0.708
striated muscle myosin thick filament assembly GO:0071688 3 0.675
muscle structure development GO:0061061 224 0.568
cellular component assembly involved in morphogenesis GO:0010927 151 0.565
protein complex assembly GO:0006461 200 0.488
muscle cell differentiation GO:0042692 103 0.450
actin cytoskeleton organization GO:0030036 206 0.343
respiratory system development GO:0060541 213 0.319
muscle cell development GO:0055001 50 0.319
striated muscle cell differentiation GO:0051146 90 0.291
regulation of protein complex disassembly GO:0043244 29 0.242
cellular protein complex assembly GO:0043623 71 0.242
striated muscle cell development GO:0055002 50 0.216
actin filament depolymerization GO:0030042 5 0.188
skeletal muscle adaptation GO:0043501 1 0.181
muscle thin filament assembly GO:0071689 5 0.175
actin filament organization GO:0007015 126 0.174
somatic muscle development GO:0007525 66 0.160
actin filament bundle organization GO:0061572 28 0.149
cellular catabolic process GO:0044248 372 0.137
regulation of organelle organization GO:0033043 196 0.127
negative regulation of actin filament depolymerization GO:0030835 2 0.114
cellular divalent inorganic cation homeostasis GO:0072503 23 0.108
regulation of molecular function GO:0065009 217 0.108
regulation of phosphorus metabolic process GO:0051174 210 0.102
adult behavior GO:0030534 137 0.101
regulation of actin filament length GO:0030832 27 0.100
macromolecular complex assembly GO:0065003 256 0.099
regulation of hydrolase activity GO:0051336 97 0.099
regulation of cellular catabolic process GO:0031329 157 0.098
muscle system process GO:0003012 21 0.095
nucleotide catabolic process GO:0009166 109 0.093
regulation of actin cytoskeleton organization GO:0032956 42 0.088
cellular macromolecular complex assembly GO:0034622 153 0.086
skeletal myofibril assembly GO:0014866 6 0.086
macromolecule catabolic process GO:0009057 161 0.084
regulation of anatomical structure morphogenesis GO:0022603 242 0.084
regulation of cytoskeleton organization GO:0051493 89 0.084
regulation of cell differentiation GO:0045595 302 0.084
striated muscle tissue development GO:0014706 27 0.082
catabolic process GO:0009056 409 0.082
organelle fission GO:0048285 340 0.079
regulation of actin polymerization or depolymerization GO:0008064 27 0.079
locomotory behavior GO:0007626 176 0.075
regulation of cell death GO:0010941 173 0.075
synapse organization GO:0050808 196 0.075
programmed cell death GO:0012501 257 0.074
positive regulation of actin filament polymerization GO:0030838 11 0.071
nuclear division GO:0000280 332 0.069
myosin filament assembly GO:0031034 5 0.067
regulation of sequestering of calcium ion GO:0051282 3 0.066
positive regulation of catalytic activity GO:0043085 118 0.065
organic substance catabolic process GO:1901575 308 0.064
cellular metal ion homeostasis GO:0006875 31 0.064
regulation of phosphate metabolic process GO:0019220 210 0.062
body morphogenesis GO:0010171 2 0.062
single organism behavior GO:0044708 391 0.062
organophosphate catabolic process GO:0046434 112 0.059
actin filament bundle assembly GO:0051017 26 0.059
purine nucleoside triphosphate catabolic process GO:0009146 108 0.058
regulation of actin filament based process GO:0032970 42 0.057
negative regulation of cytoskeleton organization GO:0051494 30 0.056
glycosyl compound catabolic process GO:1901658 112 0.056
protein complex disassembly GO:0043241 36 0.056
positive regulation of nucleoside metabolic process GO:0045979 47 0.056
skeletal muscle myosin thick filament assembly GO:0030241 3 0.055
purine nucleotide catabolic process GO:0006195 109 0.053
macromolecular complex disassembly GO:0032984 37 0.052
myosin filament organization GO:0031033 5 0.052
positive regulation of cellular catabolic process GO:0031331 95 0.051
regulation of catalytic activity GO:0050790 185 0.051
regulation of ras gtpase activity GO:0032318 38 0.051
regulation of nervous system development GO:0051960 248 0.049
protein catabolic process GO:0030163 101 0.048
mitotic nuclear division GO:0007067 213 0.047
regulation of actin filament polymerization GO:0030833 25 0.047
positive regulation of ras gtpase activity GO:0032320 36 0.046
anatomical structure homeostasis GO:0060249 97 0.046
dephosphorylation GO:0016311 51 0.045
negative regulation of protein complex disassembly GO:0043242 23 0.045
myotube cell development GO:0014904 3 0.044
metal ion homeostasis GO:0055065 44 0.044
regulation of rho gtpase activity GO:0032319 20 0.044
small molecule metabolic process GO:0044281 305 0.044
negative regulation of response to stimulus GO:0048585 258 0.043
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
cellular protein modification process GO:0006464 438 0.043
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
positive regulation of nucleotide metabolic process GO:0045981 55 0.041
ribonucleotide catabolic process GO:0009261 109 0.041
heart process GO:0003015 37 0.040
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.039
actin filament capping GO:0051693 2 0.038
mesoderm development GO:0007498 78 0.038
positive regulation of nucleotide catabolic process GO:0030813 46 0.038
imaginal disc derived appendage development GO:0048737 399 0.038
protein depolymerization GO:0051261 31 0.037
regulation of meiosis GO:0040020 3 0.037
gtp catabolic process GO:0006184 72 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
actin polymerization or depolymerization GO:0008154 31 0.036
negative regulation of cellular component organization GO:0051129 108 0.036
positive regulation of hydrolase activity GO:0051345 78 0.036
cytosolic calcium ion transport GO:0060401 2 0.035
regulation of programmed cell death GO:0043067 152 0.035
heterocycle catabolic process GO:0046700 166 0.035
ras protein signal transduction GO:0007265 88 0.035
positive regulation of cytoskeleton organization GO:0051495 21 0.035
regulation of cell development GO:0060284 215 0.034
cellular protein complex disassembly GO:0043624 35 0.033
camera type eye development GO:0043010 4 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
release of sequestered calcium ion into cytosol GO:0051209 1 0.033
organonitrogen compound catabolic process GO:1901565 128 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.033
tissue morphogenesis GO:0048729 297 0.032
positive regulation of molecular function GO:0044093 136 0.032
circulatory system development GO:0072359 82 0.032
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.032
carbohydrate derivative catabolic process GO:1901136 118 0.031
protein polymerization GO:0051258 42 0.031
purine containing compound metabolic process GO:0072521 155 0.031
nucleoside triphosphate catabolic process GO:0009143 108 0.031
biological adhesion GO:0022610 138 0.030
guanosine containing compound metabolic process GO:1901068 74 0.029
regulation of protein polymerization GO:0032271 28 0.029
organophosphate metabolic process GO:0019637 195 0.029
gtp metabolic process GO:0046039 72 0.028
regulation of catabolic process GO:0009894 170 0.028
actin filament polymerization GO:0030041 27 0.028
regulation of nucleotide metabolic process GO:0006140 62 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
ion transport GO:0006811 145 0.028
nucleoside phosphate catabolic process GO:1901292 110 0.028
ribonucleoside metabolic process GO:0009119 127 0.027
negative regulation of homeostatic process GO:0032845 2 0.027
cell adhesion GO:0007155 136 0.027
regulation of cell shape GO:0008360 113 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
aromatic compound catabolic process GO:0019439 166 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
localization of cell GO:0051674 257 0.026
purine nucleoside triphosphate metabolic process GO:0009144 119 0.026
apoptotic process GO:0006915 159 0.026
organonitrogen compound metabolic process GO:1901564 318 0.026
rho protein signal transduction GO:0007266 14 0.026
muscle tissue morphogenesis GO:0060415 2 0.025
ribose phosphate metabolic process GO:0019693 145 0.025
immune system process GO:0002376 347 0.025
regulation of cell morphogenesis GO:0022604 163 0.025
purine ribonucleoside metabolic process GO:0046128 127 0.025
purine containing compound catabolic process GO:0072523 112 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
positive regulation of organelle organization GO:0010638 65 0.024
regulation of cellular component biogenesis GO:0044087 201 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
heart contraction GO:0060047 26 0.023
guanosine containing compound catabolic process GO:1901069 74 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
regulation of protein depolymerization GO:1901879 27 0.023
regulation of purine nucleotide catabolic process GO:0033121 48 0.023
appendage development GO:0048736 401 0.022
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
positive regulation of cellular component organization GO:0051130 156 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
hematopoietic progenitor cell differentiation GO:0002244 1 0.022
stress fiber assembly GO:0043149 6 0.021
calcium ion homeostasis GO:0055074 23 0.021
cell recognition GO:0008037 102 0.021
eye development GO:0001654 323 0.021
organic substance transport GO:0071702 257 0.021
cardiac muscle tissue development GO:0048738 9 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
cell death GO:0008219 279 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
epithelial cell differentiation GO:0030855 322 0.020
phosphorylation GO:0016310 294 0.020
regulation of apoptotic process GO:0042981 130 0.020
regulation of ras protein signal transduction GO:0046578 93 0.020
regulation of gtp catabolic process GO:0033124 44 0.020
muscle contraction GO:0006936 13 0.019
regulation of rho protein signal transduction GO:0035023 20 0.019
positive regulation of catabolic process GO:0009896 105 0.019
heart development GO:0007507 82 0.019
negative regulation of molecular function GO:0044092 51 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
regulation of nucleotide catabolic process GO:0030811 48 0.019
protein secretion GO:0009306 45 0.018
regulation of nucleoside metabolic process GO:0009118 50 0.018
transmembrane transport GO:0055085 139 0.018
positive regulation of calcium ion transport GO:0051928 4 0.018
positive regulation of gtpase activity GO:0043547 43 0.018
regulation of cellular component size GO:0032535 98 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
neuron recognition GO:0008038 101 0.018
regulation of cell projection organization GO:0031344 92 0.018
striated muscle adaptation GO:0014888 1 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.017
pharynx development GO:0060465 1 0.017
vesicle mediated transport GO:0016192 381 0.017
cation transmembrane transport GO:0098655 88 0.017
ion homeostasis GO:0050801 55 0.017
cellular cation homeostasis GO:0030003 38 0.017
actin cytoskeleton reorganization GO:0031532 22 0.017
homeostatic process GO:0042592 199 0.017
regulation of heart contraction GO:0008016 21 0.017
negative regulation of sequestering of calcium ion GO:0051283 2 0.017
nucleoside catabolic process GO:0009164 112 0.017
ovulation GO:0030728 4 0.016
regulation of actin filament depolymerization GO:0030834 3 0.016
calcium ion transport into cytosol GO:0060402 2 0.016
cation transport GO:0006812 110 0.016
multi multicellular organism process GO:0044706 123 0.016
tube development GO:0035295 244 0.016
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.015
protein modification by small protein conjugation or removal GO:0070647 106 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
compound eye development GO:0048749 307 0.015
negative regulation of organelle organization GO:0010639 56 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
establishment of localization in cell GO:0051649 402 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
regulation of gtpase activity GO:0043087 44 0.015
cellular homeostasis GO:0019725 80 0.015
immune system development GO:0002520 57 0.015
divalent inorganic cation homeostasis GO:0072507 29 0.015
cation homeostasis GO:0055080 51 0.014
blood circulation GO:0008015 26 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
protein modification process GO:0036211 438 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
intracellular signal transduction GO:0035556 300 0.014
regulation of cell substrate adhesion GO:0010810 2 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
single organism intracellular transport GO:1902582 207 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
protein modification by small protein conjugation GO:0032446 79 0.013
response to oxygen containing compound GO:1901700 200 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
chemical homeostasis GO:0048878 92 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
regulation of cellular localization GO:0060341 136 0.013
cellular protein catabolic process GO:0044257 83 0.013
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.013
central nervous system development GO:0007417 201 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
neuron death GO:0070997 27 0.013
metal ion transport GO:0030001 74 0.013
negative regulation of protein depolymerization GO:1901880 23 0.013
protein localization GO:0008104 284 0.013
nucleus localization GO:0051647 34 0.013
positive regulation of atp catabolic process GO:1903291 3 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
single organism catabolic process GO:0044712 228 0.013
synapse assembly GO:0007416 143 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.012
establishment of nucleus localization GO:0040023 26 0.012
muscle adaptation GO:0043500 1 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
cardiac muscle cell differentiation GO:0055007 4 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
response to calcium ion GO:0051592 1 0.012
response to oxygen levels GO:0070482 59 0.012
hemopoiesis GO:0030097 46 0.012
wing disc morphogenesis GO:0007472 344 0.012
sequestering of calcium ion GO:0051208 5 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of protein catabolic process GO:0042176 55 0.012
establishment of blood brain barrier GO:0060856 16 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
response to metal ion GO:0010038 23 0.011
wing disc pattern formation GO:0035222 66 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
protein targeting GO:0006605 64 0.011
growth GO:0040007 359 0.011
regulation of cell cycle GO:0051726 291 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
rna processing GO:0006396 147 0.011
cytoplasmic transport GO:0016482 130 0.011
positive regulation of developmental process GO:0051094 143 0.011
cellular response to organic substance GO:0071310 132 0.011
positive chemotaxis GO:0050918 4 0.011
regulation of peptidase activity GO:0052547 39 0.011
connective tissue development GO:0061448 3 0.011
negative regulation of actin filament polymerization GO:0030837 7 0.011
behavioral response to ethanol GO:0048149 49 0.011
maintenance of location GO:0051235 73 0.011
receptor clustering GO:0043113 3 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
open tracheal system development GO:0007424 204 0.011
autophagic cell death GO:0048102 83 0.010
meiotic nuclear division GO:0007126 151 0.010
mitochondrion organization GO:0007005 65 0.010
positive regulation of transport GO:0051050 92 0.010
muscle organ development GO:0007517 127 0.010
response to endogenous stimulus GO:0009719 119 0.010
regulation of cellular component movement GO:0051270 42 0.010
cell motility GO:0048870 251 0.010
wing disc dorsal ventral pattern formation GO:0048190 47 0.010

Zasp66 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.145
myopathy DOID:423 0 0.067
muscular disease DOID:0080000 0 0.067
heart disease DOID:114 0 0.067
cardiomyopathy DOID:0050700 0 0.067
cardiovascular system disease DOID:1287 0 0.067
musculoskeletal system disease DOID:17 0 0.067
muscle tissue disease DOID:66 0 0.067
intrinsic cardiomyopathy DOID:0060036 0 0.058
dilated cardiomyopathy DOID:12930 0 0.055
central nervous system disease DOID:331 0 0.015
neurodegenerative disease DOID:1289 0 0.015
nervous system disease DOID:863 0 0.015