Drosophila melanogaster

48 known processes

Dis3 (Dmel_CG6413)

CG6413 gene product from transcript CG6413-RA

(Aliases: dis3,dRrp44,CG6413,taz,Dmel\CG6413,dDis3)

Dis3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 147 0.449
ncrna metabolic process GO:0034660 43 0.443
rrna processing GO:0006364 3 0.353
ribonucleoprotein complex biogenesis GO:0022613 31 0.301
snrna 3 end processing GO:0034472 14 0.282
ribonucleoprotein complex assembly GO:0022618 23 0.226
ribonucleoprotein complex subunit organization GO:0071826 28 0.218
ribosomal large subunit biogenesis GO:0042273 1 0.199
snrna processing GO:0016180 14 0.196
embryo development ending in birth or egg hatching GO:0009792 152 0.180
larval development GO:0002164 104 0.142
cellular macromolecular complex assembly GO:0034622 153 0.137
negative regulation of gene expression GO:0010629 387 0.126
snrna metabolic process GO:0016073 14 0.118
regulation of developmental growth GO:0048638 174 0.114
rna splicing GO:0008380 83 0.101
vesicle mediated transport GO:0016192 381 0.094
endocytosis GO:0006897 310 0.091
macromolecular complex assembly GO:0065003 256 0.076
digestive system development GO:0055123 149 0.070
regulation of gene expression epigenetic GO:0040029 128 0.069
regulation of rna splicing GO:0043484 69 0.061
negative regulation of rna biosynthetic process GO:1902679 240 0.060
organelle assembly GO:0070925 198 0.057
ncrna processing GO:0034470 30 0.056
regulation of endopeptidase activity GO:0052548 36 0.056
regulation of embryonic pattern specification GO:1902875 27 0.052
dendrite development GO:0016358 204 0.051
gene silencing GO:0016458 138 0.051
regulation of multicellular organismal development GO:2000026 414 0.049
catabolic process GO:0009056 409 0.049
positive regulation of multicellular organismal process GO:0051240 143 0.046
regulation of cell cycle process GO:0010564 181 0.045
body morphogenesis GO:0010171 2 0.045
positive regulation of macromolecule metabolic process GO:0010604 405 0.044
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.044
cell motility GO:0048870 251 0.044
determination of adult lifespan GO:0008340 137 0.043
dendrite morphogenesis GO:0048813 199 0.043
organic substance catabolic process GO:1901575 308 0.042
response to abiotic stimulus GO:0009628 341 0.042
organophosphate metabolic process GO:0019637 195 0.042
organonitrogen compound metabolic process GO:1901564 318 0.040
negative regulation of rna metabolic process GO:0051253 251 0.038
multicellular organismal aging GO:0010259 140 0.036
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.035
ncrna 3 end processing GO:0043628 17 0.035
negative regulation of cellular biosynthetic process GO:0031327 277 0.034
lipid storage GO:0019915 38 0.034
regulation of cell differentiation GO:0045595 302 0.033
regulation of mrna splicing via spliceosome GO:0048024 64 0.032
aging GO:0007568 143 0.032
posttranscriptional gene silencing GO:0016441 46 0.032
amine metabolic process GO:0009308 12 0.030
cellular protein complex assembly GO:0043623 71 0.030
establishment or maintenance of cell polarity GO:0007163 167 0.030
gene silencing by rna GO:0031047 57 0.029
telomere organization GO:0032200 21 0.029
homeostatic process GO:0042592 199 0.029
mrna splicing via spliceosome GO:0000398 73 0.028
aromatic compound catabolic process GO:0019439 166 0.028
cellular macromolecule localization GO:0070727 220 0.027
heterocycle catabolic process GO:0046700 166 0.027
mitotic g2 m transition checkpoint GO:0044818 70 0.027
regulation of mrna processing GO:0050684 71 0.026
cytokinesis GO:0000910 90 0.026
regulation of multicellular organism growth GO:0040014 40 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
developmental growth GO:0048589 280 0.025
muscle structure development GO:0061061 224 0.025
positive regulation of cell communication GO:0010647 250 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
small molecule metabolic process GO:0044281 305 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.022
positive regulation of developmental growth GO:0048639 62 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
rna 3 end processing GO:0031123 45 0.022
posttranscriptional gene silencing by rna GO:0035194 45 0.022
spindle organization GO:0007051 253 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
positive regulation of gene expression GO:0010628 290 0.021
growth GO:0040007 359 0.021
response to external biotic stimulus GO:0043207 293 0.021
mrna processing GO:0006397 104 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.020
lipid localization GO:0010876 54 0.020
rna interference GO:0016246 27 0.020
cell division GO:0051301 248 0.020
rna localization GO:0006403 115 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
regulation of meiosis GO:0040020 3 0.019
mrna metabolic process GO:0016071 124 0.019
apoptotic process GO:0006915 159 0.019
defense response GO:0006952 300 0.019
establishment of localization in cell GO:0051649 402 0.019
regulation of neurogenesis GO:0050767 158 0.019
localization of cell GO:0051674 257 0.019
rna splicing via transesterification reactions GO:0000375 73 0.018
ribosome biogenesis GO:0042254 8 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
response to other organism GO:0051707 293 0.018
protein transport GO:0015031 155 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
regulation of mrna metabolic process GO:1903311 72 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
atp metabolic process GO:0046034 49 0.016
nucleotide metabolic process GO:0009117 161 0.016
regulation of cell morphogenesis GO:0022604 163 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
defense response to bacterium GO:0042742 178 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
intracellular mrna localization GO:0008298 66 0.015
mitotic dna integrity checkpoint GO:0044774 75 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
positive regulation of developmental process GO:0051094 143 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
regulation of peptidase activity GO:0052547 39 0.015
multi organism behavior GO:0051705 175 0.015
protein complex biogenesis GO:0070271 201 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
response to biotic stimulus GO:0009607 294 0.015
appendage morphogenesis GO:0035107 397 0.015
cell proliferation GO:0008283 299 0.015
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.014
organelle fission GO:0048285 340 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
regulation of hydrolase activity GO:0051336 97 0.014
positive regulation of molecular function GO:0044093 136 0.014
positive regulation of signal transduction GO:0009967 223 0.014
positive regulation of signaling GO:0023056 243 0.014
regulation of molecular function GO:0065009 217 0.014
proteolysis GO:0006508 192 0.014
peptide metabolic process GO:0006518 80 0.014
pole plasm assembly GO:0007315 61 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
nucleoside metabolic process GO:0009116 127 0.014
oxoacid metabolic process GO:0043436 103 0.013
immune system process GO:0002376 347 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
pole plasm rna localization GO:0007316 52 0.013
regulation of catalytic activity GO:0050790 185 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
regulation of protein metabolic process GO:0051246 256 0.013
cell migration GO:0016477 238 0.012
organic acid metabolic process GO:0006082 103 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
regulation of cell cycle GO:0051726 291 0.012
mitotic spindle organization GO:0007052 220 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.012
chromatin remodeling GO:0006338 72 0.012
regulation of neuron differentiation GO:0045664 103 0.012
dna metabolic process GO:0006259 227 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
gene silencing by mirna GO:0035195 22 0.011
sex differentiation GO:0007548 81 0.011
muscle organ development GO:0007517 127 0.011
protein secretion GO:0009306 45 0.011
regulation of apoptotic process GO:0042981 130 0.011
exocrine system development GO:0035272 162 0.011
cytoplasm organization GO:0007028 64 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
nuclear division GO:0000280 332 0.011
single organism intracellular transport GO:1902582 207 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
epithelial cell differentiation GO:0030855 322 0.011
phagocytosis GO:0006909 215 0.011
negative regulation of cell cycle process GO:0010948 109 0.010
chromatin organization GO:0006325 207 0.010
positive regulation of multicellular organism growth GO:0040018 21 0.010
digestive tract morphogenesis GO:0048546 127 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
immune effector process GO:0002252 98 0.010
centrosome cycle GO:0007098 137 0.010
establishment of protein localization GO:0045184 163 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010

Dis3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.043
eye and adnexa disease DOID:1492 0 0.017
eye disease DOID:5614 0 0.017
sensory system disease DOID:0050155 0 0.017