Drosophila melanogaster

28 known processes

CG12370 (Dmel_CG12370)

CG12370 gene product from transcript CG12370-RB

(Aliases: CG13156,anon-WO0170980.104,anon-WO0170980.103,Dmel\CG12370)

CG12370 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to osmotic stress GO:0006970 14 0.107
response to abiotic stimulus GO:0009628 341 0.104
response to salt stress GO:0009651 11 0.094
positive regulation of gene expression GO:0010628 290 0.086
Rat
appendage morphogenesis GO:0035107 397 0.083
organic substance transport GO:0071702 257 0.079
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.066
organonitrogen compound metabolic process GO:1901564 318 0.064
Human Rat
positive regulation of biosynthetic process GO:0009891 316 0.064
Human Rat
cellular response to heat GO:0034605 24 0.060
regionalization GO:0003002 416 0.056
lipid metabolic process GO:0006629 121 0.055
chromosome organization GO:0051276 360 0.054
chromatin organization GO:0006325 207 0.054
transmembrane transport GO:0055085 139 0.052
Human Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.052
response to heat GO:0009408 63 0.051
macromolecular complex assembly GO:0065003 256 0.050
chromatin assembly GO:0031497 48 0.049
catabolic process GO:0009056 409 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.045
Human Rat
small molecule metabolic process GO:0044281 305 0.045
Human Rat
appendage development GO:0048736 401 0.045
positive regulation of rna biosynthetic process GO:1902680 266 0.043
ion transport GO:0006811 145 0.043
Human Rat
detection of stimulus GO:0051606 156 0.042
positive regulation of response to stimulus GO:0048584 323 0.042
Rat
dna conformation change GO:0071103 105 0.041
intracellular signal transduction GO:0035556 300 0.041
Rat
dna packaging GO:0006323 91 0.040
response to organic substance GO:0010033 284 0.040
positive regulation of signal transduction GO:0009967 223 0.040
Rat
chromatin modification GO:0016568 147 0.040
endocytosis GO:0006897 310 0.039
dorsal ventral pattern formation GO:0009953 133 0.039
cellular protein modification process GO:0006464 438 0.039
wing disc morphogenesis GO:0007472 344 0.039
oxoacid metabolic process GO:0043436 103 0.039
detection of chemical stimulus GO:0009593 93 0.038
death GO:0016265 284 0.038
Rat
cellular catabolic process GO:0044248 372 0.037
phosphorylation GO:0016310 294 0.036
Rat
regulation of localization GO:0032879 275 0.036
Human Rat
chromatin assembly or disassembly GO:0006333 52 0.035
synaptic transmission GO:0007268 288 0.034
Rat
response to temperature stimulus GO:0009266 106 0.034
single organism biosynthetic process GO:0044711 206 0.033
Human Rat
positive regulation of cell communication GO:0010647 250 0.033
Rat
localization of cell GO:0051674 257 0.033
dna metabolic process GO:0006259 227 0.033
carboxylic acid metabolic process GO:0019752 92 0.033
response to oxygen containing compound GO:1901700 200 0.033
Human Rat
positive regulation of rna metabolic process GO:0051254 271 0.032
mating GO:0007618 120 0.032
Fly
cell death GO:0008219 279 0.032
Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
Rat
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
axon guidance GO:0007411 233 0.031
regulation of anatomical structure size GO:0090066 163 0.031
single organism catabolic process GO:0044712 228 0.030
epithelial cell migration GO:0010631 148 0.030
axon development GO:0061564 297 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.030
homeostatic process GO:0042592 199 0.030
Rat
protein modification process GO:0036211 438 0.029
response to other organism GO:0051707 293 0.029
cation transport GO:0006812 110 0.029
Human Rat
single organism behavior GO:0044708 391 0.029
Rat
transcription from rna polymerase ii promoter GO:0006366 368 0.029
response to lipopolysaccharide GO:0032496 4 0.028
immune response GO:0006955 246 0.028
Rat
neurological system process GO:0050877 358 0.028
Rat
response to nutrient levels GO:0031667 114 0.028
single organism intracellular transport GO:1902582 207 0.028
Rat
positive regulation of signaling GO:0023056 243 0.027
Rat
imaginal disc pattern formation GO:0007447 91 0.027
organic acid metabolic process GO:0006082 103 0.027
regulation of intracellular signal transduction GO:1902531 236 0.027
Rat
mapk cascade GO:0000165 107 0.027
Rat
programmed cell death GO:0012501 257 0.027
ion transmembrane transport GO:0034220 122 0.027
Human Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
heterocycle catabolic process GO:0046700 166 0.026
protein complex biogenesis GO:0070271 201 0.026
phagocytosis GO:0006909 215 0.026
regulation of transport GO:0051049 181 0.026
Human Rat
establishment of localization in cell GO:0051649 402 0.026
Rat
negative regulation of developmental process GO:0051093 201 0.026
neutral lipid biosynthetic process GO:0046460 2 0.025
response to nitrogen compound GO:1901698 90 0.025
Human Rat
organic substance catabolic process GO:1901575 308 0.025
response to starvation GO:0042594 97 0.025
metal ion transport GO:0030001 74 0.025
Human Rat
chemotaxis GO:0006935 249 0.025
cellular lipid metabolic process GO:0044255 83 0.024
positive regulation of transport GO:0051050 92 0.024
Rat
oxidation reduction process GO:0055114 123 0.024
organ or tissue specific immune response GO:0002251 10 0.024
response to extracellular stimulus GO:0009991 116 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
response to external biotic stimulus GO:0043207 293 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
axonogenesis GO:0007409 290 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
positive regulation of cellular component organization GO:0051130 156 0.023
aromatic compound catabolic process GO:0019439 166 0.023
inter male aggressive behavior GO:0002121 60 0.023
compound eye development GO:0048749 307 0.023
mucosal immune response GO:0002385 10 0.023
eye development GO:0001654 323 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
membrane organization GO:0061024 112 0.023
tissue migration GO:0090130 155 0.023
protein complex assembly GO:0006461 200 0.023
regulation of chromosome organization GO:0033044 64 0.023
protein transport GO:0015031 155 0.023
chromatin remodeling GO:0006338 72 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.022
developmental maturation GO:0021700 172 0.022
inorganic ion transmembrane transport GO:0098660 73 0.022
Human
mrna metabolic process GO:0016071 124 0.022
amine metabolic process GO:0009308 12 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
salivary gland development GO:0007431 162 0.022
regulation of response to oxidative stress GO:1902882 4 0.022
aggressive behavior GO:0002118 63 0.022
secretion by cell GO:0032940 101 0.022
Rat
regulation of cellular component biogenesis GO:0044087 201 0.022
detection of stimulus involved in sensory perception GO:0050906 92 0.022
cellular response to organic substance GO:0071310 132 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
imaginal disc derived appendage development GO:0048737 399 0.021
regulation of growth GO:0040008 233 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
response to organophosphorus GO:0046683 2 0.021
neuron recognition GO:0008038 101 0.021
defense response GO:0006952 300 0.021
response to monosaccharide GO:0034284 4 0.021
Rat
regulation of catalytic activity GO:0050790 185 0.021
Human
meiotic cell cycle GO:0051321 171 0.021
developmental growth GO:0048589 280 0.021
Rat
vitamin biosynthetic process GO:0009110 1 0.020
forebrain development GO:0030900 2 0.020
Rat
response to endogenous stimulus GO:0009719 119 0.020
proteolysis GO:0006508 192 0.020
organelle fission GO:0048285 340 0.020
cellular macromolecule localization GO:0070727 220 0.020
heterochromatin organization GO:0070828 25 0.020
response to inorganic substance GO:0010035 44 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
Rat
signal transduction by phosphorylation GO:0023014 107 0.020
Rat
establishment of protein localization GO:0045184 163 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
cellular ion homeostasis GO:0006873 39 0.019
Rat
cellular macromolecule catabolic process GO:0044265 136 0.019
macromolecule catabolic process GO:0009057 161 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
Rat
developmental pigmentation GO:0048066 68 0.019
acylglycerol biosynthetic process GO:0046463 2 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.019
positive regulation of cell motility GO:2000147 3 0.019
vesicle mediated transport GO:0016192 381 0.019
Rat
response to hexose GO:0009746 3 0.019
Rat
ion homeostasis GO:0050801 55 0.019
Rat
regulation of protein metabolic process GO:0051246 256 0.019
triglyceride biosynthetic process GO:0019432 2 0.019
response to metal ion GO:0010038 23 0.019
salivary gland morphogenesis GO:0007435 145 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
Human Rat
cellular response to ethanol GO:0071361 4 0.018
regulation of cellular response to stress GO:0080135 89 0.018
Rat
compound eye morphogenesis GO:0001745 249 0.018
cellular ketone metabolic process GO:0042180 24 0.018
negative regulation of signal transduction GO:0009968 206 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
positive regulation of cell migration GO:0030335 2 0.018
locomotory behavior GO:0007626 176 0.018
Rat
single organism cellular localization GO:1902580 180 0.018
Rat
synapse organization GO:0050808 196 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
Human Rat
negative regulation of gene expression GO:0010629 387 0.017
Rat
purine nucleotide metabolic process GO:0006163 146 0.017
Human Rat
regulation of response to stress GO:0080134 200 0.017
Rat
response to bacterium GO:0009617 198 0.017
body morphogenesis GO:0010171 2 0.017
eye morphogenesis GO:0048592 260 0.017
secretion GO:0046903 109 0.017
Rat
l amino acid import GO:0043092 2 0.017
wing disc pattern formation GO:0035222 66 0.017
tissue morphogenesis GO:0048729 297 0.017
regulation of mapk cascade GO:0043408 92 0.017
Rat
lipid biosynthetic process GO:0008610 46 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
Fly
response to biotic stimulus GO:0009607 294 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
cell recognition GO:0008037 102 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
Rat
tube morphogenesis GO:0035239 191 0.016
regulation of cell differentiation GO:0045595 302 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
immune system process GO:0002376 347 0.016
Rat
cellular amine metabolic process GO:0044106 12 0.016
neuron projection guidance GO:0097485 241 0.016
ameboidal type cell migration GO:0001667 151 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
connective tissue development GO:0061448 3 0.015
insecticide catabolic process GO:0046701 1 0.015
regulation of organelle organization GO:0033043 196 0.015
respiratory system development GO:0060541 213 0.015
peptidyl amino acid modification GO:0018193 105 0.015
stress activated mapk cascade GO:0051403 52 0.015
Rat
regulation of cell cycle GO:0051726 291 0.015
vitamin metabolic process GO:0006766 2 0.015
cellular homeostasis GO:0019725 80 0.015
Rat
multi organism behavior GO:0051705 175 0.015
Fly
regulation of protein modification process GO:0031399 112 0.015
taxis GO:0042330 304 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
sensory perception GO:0007600 196 0.015
Rat
rna localization GO:0006403 115 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
growth GO:0040007 359 0.015
Rat
ribonucleotide metabolic process GO:0009259 145 0.015
Human Rat
monovalent inorganic cation transport GO:0015672 40 0.015
sensory organ morphogenesis GO:0090596 260 0.015
response to radiation GO:0009314 155 0.015
Rat
carbohydrate metabolic process GO:0005975 82 0.015
organophosphate metabolic process GO:0019637 195 0.015
Human Rat
tube development GO:0035295 244 0.015
regulation of secretion GO:0051046 44 0.015
Rat
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.015
dephosphorylation GO:0016311 51 0.015
nuclear division GO:0000280 332 0.015
anion homeostasis GO:0055081 3 0.015
polyol biosynthetic process GO:0046173 3 0.015
cation transmembrane transport GO:0098655 88 0.015
Human
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
Rat
stress activated protein kinase signaling cascade GO:0031098 55 0.015
Rat
xenobiotic catabolic process GO:0042178 1 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
Human Rat
anion transport GO:0006820 41 0.014
myotube cell development GO:0014904 3 0.014
mating behavior GO:0007617 106 0.014
Fly
medium chain fatty acid metabolic process GO:0051791 1 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
lateral inhibition GO:0046331 206 0.014
regulation of molecular function GO:0065009 217 0.014
Human Rat
intracellular transport GO:0046907 228 0.014
Rat
chemical homeostasis GO:0048878 92 0.014
Rat
sensory perception of chemical stimulus GO:0007606 116 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
aging GO:0007568 143 0.014
salivary gland histolysis GO:0035070 88 0.014
regulation of immune system process GO:0002682 176 0.014
Rat
regulation of phosphorylation GO:0042325 147 0.014
Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
protein phosphorylation GO:0006468 169 0.014
secondary metabolite catabolic process GO:0090487 1 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
regulation of cell development GO:0060284 215 0.013
negative regulation of cell cycle GO:0045786 116 0.013
regulation of cell cycle process GO:0010564 181 0.013
endomembrane system organization GO:0010256 119 0.013
camera type eye development GO:0043010 4 0.013
regulation of programmed cell death GO:0043067 152 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
regulation of cell proliferation GO:0042127 163 0.013
chemosensory behavior GO:0007635 106 0.013
rna processing GO:0006396 147 0.013
kidney development GO:0001822 3 0.013
response to organonitrogen compound GO:0010243 75 0.013
Human Rat
epithelium migration GO:0090132 148 0.013
inorganic cation transmembrane transport GO:0098662 61 0.013
Human
regulation of cellular localization GO:0060341 136 0.013
Rat
response to organic cyclic compound GO:0014070 89 0.013
Rat
cognition GO:0050890 141 0.013
Rat
protein localization GO:0008104 284 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
Human Rat
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
sensory perception of pain GO:0019233 4 0.013
Rat
cellular protein localization GO:0034613 160 0.013
larval development GO:0002164 104 0.013
positive regulation of catabolic process GO:0009896 105 0.013
cytoplasmic transport GO:0016482 130 0.013
response to glucose GO:0009749 2 0.013
Rat
apoptotic process GO:0006915 159 0.013
regulation of catabolic process GO:0009894 170 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
Human Rat
gland development GO:0048732 191 0.013
positive regulation of molecular function GO:0044093 136 0.013
Human Rat
chaeta development GO:0022416 97 0.012
nitrogen compound transport GO:0071705 85 0.012
Rat
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
axis specification GO:0009798 167 0.012
defense response to other organism GO:0098542 225 0.012
mrna catabolic process GO:0006402 33 0.012
regulation of defense response GO:0031347 102 0.012
sleep GO:0030431 49 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
digestive tract development GO:0048565 149 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
determination of adult lifespan GO:0008340 137 0.012
somatic muscle development GO:0007525 66 0.012
negative regulation of immune system process GO:0002683 50 0.012
nucleotide metabolic process GO:0009117 161 0.012
Human Rat
ras protein signal transduction GO:0007265 88 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
Human Rat
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
regulation of immune response GO:0050776 118 0.012
Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
Human Rat
developmental programmed cell death GO:0010623 138 0.011
open tracheal system development GO:0007424 204 0.011
regulation of chromatin modification GO:1903308 28 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
multi multicellular organism process GO:0044706 123 0.011
Fly
exocrine system development GO:0035272 162 0.011
cuticle development GO:0042335 86 0.011
cation homeostasis GO:0055080 51 0.011
Rat
organonitrogen compound catabolic process GO:1901565 128 0.011
translation GO:0006412 69 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
Human Rat
cellular response to biotic stimulus GO:0071216 4 0.011
response to light stimulus GO:0009416 124 0.011
Rat
pigmentation GO:0043473 75 0.011
regulation of intracellular transport GO:0032386 64 0.011
Rat
regulation of dna metabolic process GO:0051052 34 0.011
actin filament based process GO:0030029 220 0.011
Rat
positive regulation of intracellular signal transduction GO:1902533 116 0.011
Rat
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
Rat
heart development GO:0007507 82 0.011
cellular chemical homeostasis GO:0055082 40 0.011
Rat
salivary gland cell autophagic cell death GO:0035071 83 0.011
regulation of lipid metabolic process GO:0019216 15 0.011
regulation of protein localization GO:0032880 76 0.011
regulation of cellular response to oxidative stress GO:1900407 4 0.011
pigment metabolic process GO:0042440 84 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
intracellular protein transport GO:0006886 104 0.011
epithelial cell development GO:0002064 274 0.011
central nervous system development GO:0007417 201 0.011
Rat
negative regulation of protein metabolic process GO:0051248 85 0.010
monocarboxylic acid transport GO:0015718 3 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
cell cycle checkpoint GO:0000075 95 0.010
histolysis GO:0007559 102 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.010
regulation of membrane potential GO:0042391 35 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
l glutamate import GO:0051938 1 0.010
regulation of developmental growth GO:0048638 174 0.010
hyperosmotic response GO:0006972 1 0.010
epithelial cell differentiation GO:0030855 322 0.010
Rat
photoreceptor cell differentiation GO:0046530 170 0.010
negative regulation of cell death GO:0060548 81 0.010
Rat
actin filament organization GO:0007015 126 0.010
Rat
reproductive behavior GO:0019098 122 0.010
Fly
response to mechanical stimulus GO:0009612 28 0.010

CG12370 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
disease of metabolism DOID:0014667 0 0.025
cardiovascular system disease DOID:1287 0 0.022
nervous system disease DOID:863 0 0.017
hypertension DOID:10763 0 0.016
artery disease DOID:0050828 0 0.016
vascular disease DOID:178 0 0.016
essential hypertension DOID:10825 0 0.016
inherited metabolic disorder DOID:655 0 0.014
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.011