Drosophila melanogaster

0 known processes

TwdlN (Dmel_CG5476)

TweedleN

(Aliases: Dmel\CG5476,BcDNA:RE59605,CG5476,BcDNA:RE20092)

TwdlN biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
body morphogenesis GO:0010171 2 0.070
Fly
wing disc morphogenesis GO:0007472 344 0.061
appendage morphogenesis GO:0035107 397 0.061
imaginal disc derived appendage morphogenesis GO:0035114 395 0.057
imaginal disc derived wing morphogenesis GO:0007476 337 0.055
single organism behavior GO:0044708 391 0.054
catabolic process GO:0009056 409 0.050
imaginal disc derived appendage development GO:0048737 399 0.048
post embryonic appendage morphogenesis GO:0035120 385 0.045
appendage development GO:0048736 401 0.043
non sensory hair organization GO:0035316 47 0.041
growth GO:0040007 359 0.037
morphogenesis of an epithelium GO:0002009 276 0.037
regulation of anatomical structure size GO:0090066 163 0.036
defense response GO:0006952 300 0.036
protein complex biogenesis GO:0070271 201 0.034
chitin based cuticle development GO:0040003 49 0.033
Fly
developmental growth GO:0048589 280 0.033
organonitrogen compound metabolic process GO:1901564 318 0.032
epithelial cell differentiation GO:0030855 322 0.031
regulation of cell differentiation GO:0045595 302 0.031
regulation of cellular component biogenesis GO:0044087 201 0.031
macromolecular complex assembly GO:0065003 256 0.030
nuclear division GO:0000280 332 0.030
organelle fission GO:0048285 340 0.030
imaginal disc derived wing hair organization GO:0035317 45 0.030
vesicle mediated transport GO:0016192 381 0.029
regulation of epithelial cell differentiation GO:0030856 4 0.029
organic substance catabolic process GO:1901575 308 0.028
tissue morphogenesis GO:0048729 297 0.028
response to abiotic stimulus GO:0009628 341 0.028
proteolysis GO:0006508 192 0.028
phosphorylation GO:0016310 294 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
cellular catabolic process GO:0044248 372 0.027
cell division GO:0051301 248 0.026
negative regulation of gene expression GO:0010629 387 0.026
regulation of protein metabolic process GO:0051246 256 0.025
establishment of localization in cell GO:0051649 402 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
protein modification process GO:0036211 438 0.025
immune response GO:0006955 246 0.024
positive regulation of cell communication GO:0010647 250 0.024
small molecule metabolic process GO:0044281 305 0.024
death GO:0016265 284 0.024
wound healing GO:0042060 75 0.024
regulation of localization GO:0032879 275 0.024
establishment of tissue polarity GO:0007164 87 0.024
kidney development GO:0001822 3 0.024
regionalization GO:0003002 416 0.023
immune system process GO:0002376 347 0.023
organic substance transport GO:0071702 257 0.023
organic acid metabolic process GO:0006082 103 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
columnar cuboidal epithelial cell development GO:0002066 249 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
cuticle development GO:0042335 86 0.022
Fly
innate immune response GO:0045087 144 0.022
response to wounding GO:0009611 94 0.022
cell death GO:0008219 279 0.021
open tracheal system development GO:0007424 204 0.021
response to temperature stimulus GO:0009266 106 0.021
positive regulation of signaling GO:0023056 243 0.021
oxoacid metabolic process GO:0043436 103 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
epithelial cell development GO:0002064 274 0.020
establishment of planar polarity GO:0001736 87 0.020
intracellular signal transduction GO:0035556 300 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
cellular protein modification process GO:0006464 438 0.020
response to organic substance GO:0010033 284 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
phagocytosis GO:0006909 215 0.020
protein complex assembly GO:0006461 200 0.020
hair cell differentiation GO:0035315 47 0.020
apoptotic process GO:0006915 159 0.019
regulation of organelle organization GO:0033043 196 0.019
response to organophosphorus GO:0046683 2 0.019
cell adhesion GO:0007155 136 0.019
multi organism behavior GO:0051705 175 0.019
mitotic nuclear division GO:0007067 213 0.019
tube morphogenesis GO:0035239 191 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
adult behavior GO:0030534 137 0.018
l glutamate import GO:0051938 1 0.018
morphogenesis of a polarized epithelium GO:0001738 93 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
regulation of cell cycle GO:0051726 291 0.018
positive regulation of gene expression GO:0010628 290 0.018
neurological system process GO:0050877 358 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
intracellular transport GO:0046907 228 0.018
mrna metabolic process GO:0016071 124 0.018
cellular macromolecule localization GO:0070727 220 0.018
taxis GO:0042330 304 0.017
peptide metabolic process GO:0006518 80 0.017
actin filament organization GO:0007015 126 0.017
negative regulation of organelle organization GO:0010639 56 0.017
regulation of apoptotic process GO:0042981 130 0.017
response to oxygen containing compound GO:1901700 200 0.017
response to radiation GO:0009314 155 0.017
chromosome segregation GO:0007059 157 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
l amino acid import GO:0043092 2 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
positive regulation of signal transduction GO:0009967 223 0.016
connective tissue development GO:0061448 3 0.016
developmental maturation GO:0021700 172 0.016
positive regulation of cell migration GO:0030335 2 0.016
epidermis development GO:0008544 65 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
single organism biosynthetic process GO:0044711 206 0.016
programmed cell death GO:0012501 257 0.016
salt aversion GO:0035199 3 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
sterol homeostasis GO:0055092 4 0.016
compound eye development GO:0048749 307 0.016
macromolecule catabolic process GO:0009057 161 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
regulation of developmental growth GO:0048638 174 0.016
regulation of cell death GO:0010941 173 0.016
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.016
autophagic cell death GO:0048102 83 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
chromosome organization GO:0051276 360 0.016
cellular amine metabolic process GO:0044106 12 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
establishment of protein localization GO:0045184 163 0.015
synaptic transmission GO:0007268 288 0.015
regulation of epidermal cell differentiation GO:0045604 3 0.015
positive regulation of cell motility GO:2000147 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of organ morphogenesis GO:2000027 78 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
protein phosphorylation GO:0006468 169 0.015
developmental programmed cell death GO:0010623 138 0.015
camera type eye development GO:0043010 4 0.015
response to light stimulus GO:0009416 124 0.015
establishment of organelle localization GO:0051656 122 0.015
locomotory behavior GO:0007626 176 0.015
regulation of protein complex assembly GO:0043254 42 0.015
regulation of transport GO:0051049 181 0.015
regulation of establishment of planar polarity GO:0090175 22 0.014
chaeta development GO:0022416 97 0.014
skin development GO:0043588 65 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
regulation of cell cycle process GO:0010564 181 0.014
regulation of cellular component size GO:0032535 98 0.014
tissue death GO:0016271 102 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
protein transport GO:0015031 155 0.014
gland development GO:0048732 191 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
rna processing GO:0006396 147 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
spindle organization GO:0007051 253 0.014
humoral immune response GO:0006959 117 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
amine metabolic process GO:0009308 12 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
respiratory system development GO:0060541 213 0.013
salivary gland development GO:0007431 162 0.013
epidermal cell differentiation GO:0009913 51 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
ion transport GO:0006811 145 0.013
single organism catabolic process GO:0044712 228 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
epithelium migration GO:0090132 148 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
compound eye morphogenesis GO:0001745 249 0.013
cellular ketone metabolic process GO:0042180 24 0.013
mapk cascade GO:0000165 107 0.013
aging GO:0007568 143 0.013
exocrine system development GO:0035272 162 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
response to biotic stimulus GO:0009607 294 0.013
response to other organism GO:0051707 293 0.013
chorion containing eggshell formation GO:0007304 105 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of catalytic activity GO:0050790 185 0.013
cell motility GO:0048870 251 0.013
regulation of cell division GO:0051302 72 0.013
hindbrain development GO:0030902 2 0.013
ion transmembrane transport GO:0034220 122 0.013
regulation of reproductive process GO:2000241 54 0.013
cell proliferation GO:0008283 299 0.013
forebrain development GO:0030900 2 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
notch signaling pathway GO:0007219 120 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
protein catabolic process GO:0030163 101 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
actin cytoskeleton organization GO:0030036 206 0.013
ras protein signal transduction GO:0007265 88 0.013
cellular protein complex assembly GO:0043623 71 0.013
telencephalon development GO:0021537 2 0.013
regulation of cell development GO:0060284 215 0.013
multicellular organismal aging GO:0010259 140 0.013
cell migration GO:0016477 238 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
response to external biotic stimulus GO:0043207 293 0.012
salivary gland morphogenesis GO:0007435 145 0.012
tube development GO:0035295 244 0.012
ameboidal type cell migration GO:0001667 151 0.012
regulation of programmed cell death GO:0043067 152 0.012
response to lipopolysaccharide GO:0032496 4 0.012
homeostatic process GO:0042592 199 0.012
protein localization GO:0008104 284 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
segmentation GO:0035282 207 0.012
response to monosaccharide GO:0034284 4 0.012
response to hexose GO:0009746 3 0.012
triglyceride biosynthetic process GO:0019432 2 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
sensory perception of pain GO:0019233 4 0.012
endocytosis GO:0006897 310 0.012
rna localization GO:0006403 115 0.012
regulation of actin filament based process GO:0032970 42 0.012
camera type eye morphogenesis GO:0048593 2 0.012
cell cycle phase transition GO:0044770 140 0.012
digestive system development GO:0055123 149 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
lateral inhibition GO:0046331 206 0.012
monocarboxylic acid transport GO:0015718 3 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
chemotaxis GO:0006935 249 0.012
mating behavior GO:0007617 106 0.012
localization of cell GO:0051674 257 0.012
regulation of synapse assembly GO:0051963 94 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
cation transport GO:0006812 110 0.012
cholesterol homeostasis GO:0042632 3 0.012
organelle localization GO:0051640 148 0.012
anion homeostasis GO:0055081 3 0.012
single organism intracellular transport GO:1902582 207 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
heterocycle catabolic process GO:0046700 166 0.011
positive regulation of molecular function GO:0044093 136 0.011
biological adhesion GO:0022610 138 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
transmembrane transport GO:0055085 139 0.011
mitotic cytokinesis GO:0000281 50 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
cellular amide metabolic process GO:0043603 80 0.011
determination of adult lifespan GO:0008340 137 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of cellular localization GO:0060341 136 0.011
aromatic compound catabolic process GO:0019439 166 0.011
response to glucose GO:0009749 2 0.011
protein polymerization GO:0051258 42 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
reproductive behavior GO:0019098 122 0.011
negative regulation of cytoskeleton organization GO:0051494 30 0.011
activation of innate immune response GO:0002218 4 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
regulation of synapse organization GO:0050807 110 0.011
establishment of proximal distal cell polarity GO:0022606 4 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
salivary gland histolysis GO:0035070 88 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
eggshell chorion assembly GO:0007306 66 0.011
multi multicellular organism process GO:0044706 123 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
wnt signaling pathway GO:0016055 98 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
gene silencing GO:0016458 138 0.011
actin filament polymerization GO:0030041 27 0.011
steroid catabolic process GO:0006706 1 0.011
limb development GO:0060173 1 0.011
embryonic pattern specification GO:0009880 174 0.011
single organism cellular localization GO:1902580 180 0.011
regulation of lipid transport GO:0032368 3 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
protein heterooligomerization GO:0051291 4 0.011
purine containing compound metabolic process GO:0072521 155 0.011
cytokinesis GO:0000910 90 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
protein maturation GO:0051604 71 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
sensory perception of salty taste GO:0050914 3 0.011
histolysis GO:0007559 102 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
nephron development GO:0072006 3 0.011
nucleotide metabolic process GO:0009117 161 0.011
regulation of response to stress GO:0080134 200 0.011
response to bacterium GO:0009617 198 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
intracellular protein transport GO:0006886 104 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
synapse organization GO:0050808 196 0.010
regulation of tube size open tracheal system GO:0035151 43 0.010
male gamete generation GO:0048232 201 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
larval development GO:0002164 104 0.010
regulation of mapk cascade GO:0043408 92 0.010
hormone catabolic process GO:0042447 3 0.010
actin filament based process GO:0030029 220 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
mitotic spindle organization GO:0007052 220 0.010
eye morphogenesis GO:0048592 260 0.010
regulation of tube architecture open tracheal system GO:0035152 68 0.010
xenobiotic catabolic process GO:0042178 1 0.010
retina development in camera type eye GO:0060041 4 0.010
mrna processing GO:0006397 104 0.010
gland morphogenesis GO:0022612 145 0.010
regulation of growth GO:0040008 233 0.010
immune response activating signal transduction GO:0002757 2 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
protein processing GO:0016485 68 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
eggshell formation GO:0030703 105 0.010
defense response to other organism GO:0098542 225 0.010
regulation of catabolic process GO:0009894 170 0.010
cellular response to monosaccharide stimulus GO:0071326 2 0.010
spermatogenesis GO:0007283 200 0.010
organophosphate metabolic process GO:0019637 195 0.010

TwdlN disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
disease of metabolism DOID:0014667 0 0.025
nervous system disease DOID:863 0 0.022
diabetes mellitus DOID:9351 0 0.019
carbohydrate metabolism disease DOID:0050013 0 0.019
glucose metabolism disease DOID:4194 0 0.019
acquired metabolic disease DOID:0060158 0 0.019
urinary system disease DOID:18 0 0.016
cardiovascular system disease DOID:1287 0 0.016
renal tubular transport disease DOID:447 0 0.015
kidney disease DOID:557 0 0.015
inherited metabolic disorder DOID:655 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
type 2 diabetes mellitus DOID:9352 0 0.010
central nervous system disease DOID:331 0 0.010