Drosophila melanogaster

112 known processes

Hdac3 (Dmel_CG2128)

Histone deacetylase 3

(Aliases: HDAC3,dmHDA402,Dromel_CG2128_FBtr0078767_hdac3_mORF,DHDAC3,DmHDAC3,dHDAC3,hdac3,CG2128,HDAC,Dmel\CG2128)

Hdac3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mitotic cell cycle phase transition GO:1901990 130 0.744
mitotic cell cycle phase transition GO:0044772 138 0.695
negative regulation of gene expression GO:0010629 387 0.685
regulation of cell cycle GO:0051726 291 0.675
negative regulation of cellular metabolic process GO:0031324 382 0.603
negative regulation of cell cycle phase transition GO:1901988 103 0.568
regulation of cell cycle phase transition GO:1901987 130 0.500
cell cycle checkpoint GO:0000075 95 0.478
negative regulation of transcription dna templated GO:0045892 237 0.436
muscle structure development GO:0061061 224 0.428
negative regulation of response to stimulus GO:0048585 258 0.392
mitotic cell cycle checkpoint GO:0007093 88 0.319
posttranscriptional gene silencing by rna GO:0035194 45 0.318
growth GO:0040007 359 0.311
embryo development ending in birth or egg hatching GO:0009792 152 0.270
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.259
negative regulation of mitotic cell cycle GO:0045930 109 0.248
negative regulation of cell cycle process GO:0010948 109 0.238
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.237
posttranscriptional regulation of gene expression GO:0010608 145 0.234
negative regulation of rna biosynthetic process GO:1902679 240 0.229
posttranscriptional gene silencing GO:0016441 46 0.225
regulation of mitotic cell cycle GO:0007346 190 0.225
mitotic dna damage checkpoint GO:0044773 74 0.224
developmental pigmentation GO:0048066 68 0.205
regulation of phosphate metabolic process GO:0019220 210 0.204
response to abiotic stimulus GO:0009628 341 0.199
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.186
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.171
nucleosome organization GO:0034728 59 0.158
spindle organization GO:0007051 253 0.158
negative regulation of biosynthetic process GO:0009890 277 0.146
developmental growth GO:0048589 280 0.145
mitotic dna integrity checkpoint GO:0044774 75 0.142
negative regulation of nucleic acid templated transcription GO:1903507 240 0.140
dendrite development GO:0016358 204 0.140
negative regulation of cell cycle GO:0045786 116 0.139
cell division GO:0051301 248 0.139
regulation of programmed cell death GO:0043067 152 0.134
cell proliferation GO:0008283 299 0.130
cell cycle phase transition GO:0044770 140 0.129
negative regulation of cellular biosynthetic process GO:0031327 277 0.125
cellular protein modification process GO:0006464 438 0.124
positive regulation of developmental process GO:0051094 143 0.123
regulation of cell cycle process GO:0010564 181 0.122
peptidyl lysine acetylation GO:0018394 39 0.120
regulation of protein metabolic process GO:0051246 256 0.116
phosphorylation GO:0016310 294 0.109
mitotic g2 m transition checkpoint GO:0044818 70 0.099
pigmentation GO:0043473 75 0.099
positive regulation of rna biosynthetic process GO:1902680 266 0.099
positive regulation of response to stimulus GO:0048584 323 0.090
regulation of gene expression epigenetic GO:0040029 128 0.090
regulation of organelle organization GO:0033043 196 0.088
negative regulation of phosphorus metabolic process GO:0010563 45 0.083
larval development GO:0002164 104 0.082
Worm
regulation of response to stress GO:0080134 200 0.082
cellular catabolic process GO:0044248 372 0.081
response to radiation GO:0009314 155 0.079
cellular response to dna damage stimulus GO:0006974 223 0.078
cuticle pigmentation GO:0048067 22 0.076
cellular amine metabolic process GO:0044106 12 0.075
protein phosphorylation GO:0006468 169 0.075
dna metabolic process GO:0006259 227 0.073
Worm
regulation of phosphorus metabolic process GO:0051174 210 0.073
regulation of protein stability GO:0031647 43 0.070
single organism biosynthetic process GO:0044711 206 0.070
organelle fission GO:0048285 340 0.069
gene silencing by rna GO:0031047 57 0.069
regulation of cell proliferation GO:0042127 163 0.069
positive regulation of gene expression GO:0010628 290 0.069
small molecule metabolic process GO:0044281 305 0.069
regulation of cellular response to stress GO:0080135 89 0.069
positive regulation of phosphate metabolic process GO:0045937 139 0.068
positive regulation of cellular biosynthetic process GO:0031328 316 0.068
regulation of cell death GO:0010941 173 0.066
meiotic nuclear division GO:0007126 151 0.063
autophagy GO:0006914 108 0.061
regulation of cell differentiation GO:0045595 302 0.058
catabolic process GO:0009056 409 0.057
regulation of cell size GO:0008361 63 0.056
regulation of response to extracellular stimulus GO:0032104 18 0.055
response to oxygen containing compound GO:1901700 200 0.055
pigment metabolic process involved in pigmentation GO:0043474 33 0.054
peptidyl amino acid modification GO:0018193 105 0.054
body morphogenesis GO:0010171 2 0.052
nuclear division GO:0000280 332 0.051
negative regulation of phosphorylation GO:0042326 35 0.050
regulation of multicellular organismal development GO:2000026 414 0.050
taxis GO:0042330 304 0.049
regulation of phosphorylation GO:0042325 147 0.049
rna interference GO:0016246 27 0.049
neuron projection guidance GO:0097485 241 0.049
dna integrity checkpoint GO:0031570 81 0.046
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.046
protein modification process GO:0036211 438 0.045
regulation of cell development GO:0060284 215 0.045
amine metabolic process GO:0009308 12 0.044
organelle assembly GO:0070925 198 0.043
regulation of nervous system development GO:0051960 248 0.041
single organism catabolic process GO:0044712 228 0.041
organic substance catabolic process GO:1901575 308 0.040
genitalia development GO:0048806 26 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.039
multi organism behavior GO:0051705 175 0.039
regulation of cellular protein metabolic process GO:0032268 243 0.038
response to temperature stimulus GO:0009266 106 0.037
oxoacid metabolic process GO:0043436 103 0.037
programmed cell death GO:0012501 257 0.037
eye development GO:0001654 323 0.036
positive regulation of phosphorylation GO:0042327 87 0.036
dna damage checkpoint GO:0000077 78 0.035
organic acid metabolic process GO:0006082 103 0.034
g2 dna damage checkpoint GO:0031572 69 0.034
erbb signaling pathway GO:0038127 58 0.034
macromolecular complex assembly GO:0065003 256 0.034
protein acetylation GO:0006473 39 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
protein complex assembly GO:0006461 200 0.032
cellular macromolecule catabolic process GO:0044265 136 0.031
gene silencing GO:0016458 138 0.031
production of mirnas involved in gene silencing by mirna GO:0035196 10 0.031
rna processing GO:0006396 147 0.030
regulation of protein kinase activity GO:0045859 51 0.030
chromatin modification GO:0016568 147 0.030
axonogenesis GO:0007409 290 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.028
cellular response to peptide hormone stimulus GO:0071375 28 0.027
regulation of cellular catabolic process GO:0031329 157 0.027
signal transduction by phosphorylation GO:0023014 107 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
dendrite morphogenesis GO:0048813 199 0.027
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
regulation of mapk cascade GO:0043408 92 0.026
reproductive structure development GO:0048608 74 0.026
reproductive system development GO:0061458 74 0.026
cellular response to insulin stimulus GO:0032869 28 0.026
defense response GO:0006952 300 0.026
regulation of chromosome segregation GO:0051983 32 0.025
mitochondrion organization GO:0007005 65 0.025
cell death GO:0008219 279 0.025
regulation of autophagy GO:0010506 62 0.025
regulation of apoptotic process GO:0042981 130 0.024
chromosome organization GO:0051276 360 0.024
cellular response to hormone stimulus GO:0032870 44 0.023
reproductive behavior GO:0019098 122 0.023
positive regulation of mapk cascade GO:0043410 63 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
regulation of molecular function GO:0065009 217 0.023
organelle localization GO:0051640 148 0.022
regulation of protein modification process GO:0031399 112 0.022
negative regulation of protein metabolic process GO:0051248 85 0.022
regulation of transferase activity GO:0051338 58 0.022
regulation of anatomical structure size GO:0090066 163 0.022
signal transduction in response to dna damage GO:0042770 3 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
epidermal growth factor receptor signaling pathway GO:0007173 58 0.021
stem cell development GO:0048864 79 0.020
regulation of catalytic activity GO:0050790 185 0.020
cellular response to organic substance GO:0071310 132 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
histone modification GO:0016570 106 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
regulation of erbb signaling pathway GO:1901184 42 0.019
regulation of cell division GO:0051302 72 0.019
positive regulation of molecular function GO:0044093 136 0.019
centrosome organization GO:0051297 163 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
peptidyl lysine modification GO:0018205 57 0.019
negative regulation of signal transduction GO:0009968 206 0.018
protein acylation GO:0043543 42 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
regionalization GO:0003002 416 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
nuclear export GO:0051168 24 0.018
atp dependent chromatin remodeling GO:0043044 22 0.018
cellular ketone metabolic process GO:0042180 24 0.018
macromolecule catabolic process GO:0009057 161 0.018
positive regulation of cell communication GO:0010647 250 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
carboxylic acid metabolic process GO:0019752 92 0.016
regulation of cellular component size GO:0032535 98 0.016
negative regulation of molecular function GO:0044092 51 0.016
muscle organ development GO:0007517 127 0.016
regulation of protein deacetylation GO:0090311 2 0.016
circadian behavior GO:0048512 76 0.016
histone exchange GO:0043486 21 0.015
response to light stimulus GO:0009416 124 0.015
response to organic substance GO:0010033 284 0.015
negative regulation of cell proliferation GO:0008285 69 0.015
transcription from rna polymerase iii promoter GO:0006383 8 0.015
mitotic spindle organization GO:0007052 220 0.015
death GO:0016265 284 0.015
meiotic cell cycle GO:0051321 171 0.015
synapse organization GO:0050808 196 0.015
internal protein amino acid acetylation GO:0006475 38 0.015
chromatin silencing GO:0006342 76 0.014
digestive tract development GO:0048565 149 0.014
negative regulation of protein phosphorylation GO:0001933 17 0.014
vesicle mediated transport GO:0016192 381 0.014
proteolysis GO:0006508 192 0.014
cellular response to nitrogen compound GO:1901699 51 0.014
regulation of catabolic process GO:0009894 170 0.013
gonad development GO:0008406 50 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of transport GO:0051049 181 0.013
regulation of response to external stimulus GO:0032101 115 0.013
mapk cascade GO:0000165 107 0.013
endocytosis GO:0006897 310 0.013
regulation of translation GO:0006417 56 0.013
regulation of meiosis GO:0040020 3 0.013
negative regulation of chromatin silencing GO:0031936 9 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
cellular response to peptide GO:1901653 28 0.012
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.012
regulation of neuron differentiation GO:0045664 103 0.012
ras protein signal transduction GO:0007265 88 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
regulation of developmental growth GO:0048638 174 0.012
chemotaxis GO:0006935 249 0.012
organonitrogen compound metabolic process GO:1901564 318 0.012
asymmetric protein localization GO:0008105 33 0.012
nitrogen compound transport GO:0071705 85 0.012
negative regulation of signaling GO:0023057 219 0.011
negative regulation of kinase activity GO:0033673 16 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
apical junction assembly GO:0043297 32 0.011
ribonucleoprotein complex assembly GO:0022618 23 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
neurological system process GO:0050877 358 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of macroautophagy GO:0016241 15 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
negative regulation of cell division GO:0051782 17 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
lipid homeostasis GO:0055088 33 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
maintenance of location GO:0051235 73 0.010
response to nutrient levels GO:0031667 114 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
regulation of histone modification GO:0031056 20 0.010
translation GO:0006412 69 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
protein complex biogenesis GO:0070271 201 0.010
lipid biosynthetic process GO:0008610 46 0.010
morphogenesis of a branching structure GO:0001763 45 0.010

Hdac3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.027