Drosophila melanogaster

50 known processes

PGRP-LB (Dmel_CG14704)

Peptidoglycan recognition protein LB

(Aliases: CG14704,Dmel\CG14704)

PGRP-LB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
activation of innate immune response GO:0002218 4 0.568
Fly
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.568
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.548
Fly
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.528
defense response to bacterium GO:0042742 178 0.497
defense response to virus GO:0051607 23 0.484
Fly
immune system process GO:0002376 347 0.475
Fly
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.442
regulation of response to biotic stimulus GO:0002831 63 0.403
regulation of defense response to bacterium GO:1900424 30 0.386
defense response to other organism GO:0098542 225 0.384
immune response GO:0006955 246 0.349
Fly
response to external biotic stimulus GO:0043207 293 0.340
response to other organism GO:0051707 293 0.317
innate immune response GO:0045087 144 0.311
Fly
defense response GO:0006952 300 0.311
defense response to gram negative bacterium GO:0050829 94 0.309
Fly
response to biotic stimulus GO:0009607 294 0.302
regulation of response to external stimulus GO:0032101 115 0.290
regulation of defense response GO:0031347 102 0.283
antimicrobial humoral response GO:0019730 99 0.267
Fly
response to bacterium GO:0009617 198 0.250
glycosaminoglycan catabolic process GO:0006027 3 0.238
Fly
negative regulation of immune system process GO:0002683 50 0.212
Fly
negative regulation of defense response GO:0031348 35 0.202
immune effector process GO:0002252 98 0.201
Fly
humoral immune response GO:0006959 117 0.192
Fly
regulation of innate immune response GO:0045088 71 0.191
Fly
regulation of immune system process GO:0002682 176 0.177
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.170
Fly
response to peptidoglycan GO:0032494 2 0.164
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.159
Fly
determination of adult lifespan GO:0008340 137 0.158
Fly
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.156
Fly
secondary metabolic process GO:0019748 75 0.151
Fly
regulation of multi organism process GO:0043900 131 0.147
multicellular organismal aging GO:0010259 140 0.145
Fly
negative regulation of response to stimulus GO:0048585 258 0.144
regulation of immune response GO:0050776 118 0.141
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.137
Fly
negative regulation of signal transduction GO:0009968 206 0.132
regulation of antimicrobial humoral response GO:0002759 50 0.130
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.129
Fly
negative regulation of signaling GO:0023057 219 0.123
negative regulation of response to external stimulus GO:0032102 22 0.118
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.116
Fly
innate immune response activating signal transduction GO:0002758 2 0.115
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.113
Fly
phosphorylation GO:0016310 294 0.111
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.110
Fly
defense response to fungus GO:0050832 48 0.108
positive regulation of antimicrobial peptide production GO:0002225 28 0.106
Fly
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.104
Fly
regulation of mapk cascade GO:0043408 92 0.099
Fly
intracellular signal transduction GO:0035556 300 0.097
Fly
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.097
Fly
amide biosynthetic process GO:0043604 42 0.094
Fly
antibacterial peptide production GO:0002778 22 0.093
Fly
regulation of intracellular signal transduction GO:1902531 236 0.090
Fly
immune response activating signal transduction GO:0002757 2 0.086
Fly
positive regulation of defense response to bacterium GO:1900426 23 0.086
Fly
positive regulation of response to stimulus GO:0048584 323 0.086
Fly
negative regulation of defense response to bacterium GO:1900425 7 0.085
immune response regulating signaling pathway GO:0002764 2 0.084
Fly
peptidoglycan metabolic process GO:0000270 3 0.083
Fly
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.081
Fly
positive regulation of immune effector process GO:0002699 28 0.079
Fly
positive regulation of multi organism process GO:0043902 40 0.076
Fly
negative regulation of immune response GO:0050777 39 0.075
Fly
catabolic process GO:0009056 409 0.075
Fly
organonitrogen compound metabolic process GO:1901564 318 0.074
Fly
aging GO:0007568 143 0.074
Fly
melanization defense response GO:0035006 45 0.070
Fly
response to lipopolysaccharide GO:0032496 4 0.070
Fly
peptidoglycan catabolic process GO:0009253 3 0.068
Fly
vesicle mediated transport GO:0016192 381 0.067
positive regulation of biosynthetic process GO:0009891 316 0.066
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.064
Fly
small molecule metabolic process GO:0044281 305 0.063
cellular response to lipopolysaccharide GO:0071222 3 0.062
Fly
carboxylic acid metabolic process GO:0019752 92 0.062
antimicrobial peptide production GO:0002775 46 0.062
Fly
melanin metabolic process GO:0006582 47 0.060
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.060
Fly
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.060
Fly
regulation of immune effector process GO:0002697 52 0.060
Fly
positive regulation of immune system process GO:0002684 68 0.057
Fly
response to abiotic stimulus GO:0009628 341 0.056
positive regulation of antimicrobial humoral response GO:0002760 28 0.056
Fly
appendage development GO:0048736 401 0.055
negative regulation of cell communication GO:0010648 223 0.055
single organism biosynthetic process GO:0044711 206 0.055
positive regulation of humoral immune response GO:0002922 28 0.055
Fly
antibacterial humoral response GO:0019731 44 0.054
Fly
antimicrobial peptide biosynthetic process GO:0002777 38 0.051
Fly
organic hydroxy compound metabolic process GO:1901615 83 0.051
Fly
negative regulation of innate immune response GO:0045824 30 0.051
Fly
positive regulation of antibacterial peptide production GO:0002803 20 0.050
Fly
negative regulation of intracellular signal transduction GO:1902532 57 0.050
Fly
positive regulation of response to external stimulus GO:0032103 44 0.050
Fly
regulation of cellular response to stress GO:0080135 89 0.050
Fly
response to virus GO:0009615 28 0.049
Fly
regulation of humoral immune response GO:0002920 51 0.049
Fly
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.049
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.049
Fly
positive regulation of signal transduction GO:0009967 223 0.048
regulation of antimicrobial peptide production GO:0002784 44 0.048
Fly
cellular catabolic process GO:0044248 372 0.048
regulation of production of molecular mediator of immune response GO:0002700 44 0.048
Fly
organic substance catabolic process GO:1901575 308 0.048
Fly
negative regulation of multi organism process GO:0043901 29 0.046
positive regulation of signaling GO:0023056 243 0.046
regulation of phosphate metabolic process GO:0019220 210 0.046
Fly
pigment metabolic process GO:0042440 84 0.045
Fly
regulation of response to stress GO:0080134 200 0.045
organonitrogen compound catabolic process GO:1901565 128 0.045
Fly
positive regulation of cell communication GO:0010647 250 0.045
response to organic substance GO:0010033 284 0.045
Fly
production of molecular mediator of immune response GO:0002440 46 0.044
Fly
defense response to gram positive bacterium GO:0050830 41 0.044
positive regulation of immune response GO:0050778 63 0.042
Fly
killing of cells of other organism GO:0031640 1 0.042
aminoglycan catabolic process GO:0006026 6 0.041
Fly
imaginal disc derived appendage development GO:0048737 399 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.039
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.039
Fly
phenol containing compound metabolic process GO:0018958 57 0.038
Fly
response to fungus GO:0009620 50 0.038
response to oxygen containing compound GO:1901700 200 0.038
Fly
cellular response to chemical stimulus GO:0070887 199 0.037
Fly
single organism catabolic process GO:0044712 228 0.037
positive regulation of response to biotic stimulus GO:0002833 31 0.036
Fly
macromolecule catabolic process GO:0009057 161 0.036
Fly
appendage morphogenesis GO:0035107 397 0.036
stress activated mapk cascade GO:0051403 52 0.036
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.036
regulation of antibacterial peptide production GO:0002786 22 0.034
Fly
response to organonitrogen compound GO:0010243 75 0.034
Fly
endocytosis GO:0006897 310 0.034
glycosaminoglycan metabolic process GO:0030203 11 0.034
Fly
regionalization GO:0003002 416 0.033
signal transduction by phosphorylation GO:0023014 107 0.033
Fly
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.033
Fly
negative regulation of phosphorylation GO:0042326 35 0.032
Fly
response to endogenous stimulus GO:0009719 119 0.032
Fly
regulation of multicellular organismal development GO:2000026 414 0.031
aminoglycan metabolic process GO:0006022 18 0.031
Fly
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.031
Fly
regulation of stress activated mapk cascade GO:0032872 41 0.030
Fly
cellular response to biotic stimulus GO:0071216 4 0.030
Fly
response to organophosphorus GO:0046683 2 0.030
carbohydrate derivative catabolic process GO:1901136 118 0.029
Fly
body morphogenesis GO:0010171 2 0.029
organophosphate metabolic process GO:0019637 195 0.029
positive regulation of defense response GO:0031349 59 0.028
Fly
antibacterial peptide biosynthetic process GO:0002780 22 0.028
Fly
negative regulation of developmental process GO:0051093 201 0.028
neurological system process GO:0050877 358 0.028
single organism behavior GO:0044708 391 0.028
antifungal humoral response GO:0019732 12 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
positive regulation of gene expression GO:0010628 290 0.027
regulation of catalytic activity GO:0050790 185 0.027
negative regulation of response to biotic stimulus GO:0002832 12 0.027
cellular amide metabolic process GO:0043603 80 0.027
Fly
ameboidal type cell migration GO:0001667 151 0.027
organic acid metabolic process GO:0006082 103 0.027
developmental pigmentation GO:0048066 68 0.027
negative regulation of phosphate metabolic process GO:0045936 45 0.027
Fly
mapk cascade GO:0000165 107 0.026
Fly
camera type eye development GO:0043010 4 0.026
positive regulation of cell migration GO:0030335 2 0.025
open tracheal system development GO:0007424 204 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
connective tissue development GO:0061448 3 0.025
axis specification GO:0009798 167 0.024
dorsal ventral pattern formation GO:0009953 133 0.024
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.024
Fly
positive regulation of rna metabolic process GO:0051254 271 0.023
response to nitrogen compound GO:1901698 90 0.023
Fly
cell death GO:0008219 279 0.023
cellular protein modification process GO:0006464 438 0.023
fat soluble vitamin biosynthetic process GO:0042362 1 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
neutral lipid biosynthetic process GO:0046460 2 0.023
secondary metabolite biosynthetic process GO:0044550 24 0.023
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of cell cycle GO:0051726 291 0.022
jnk cascade GO:0007254 50 0.022
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.022
phagocytosis GO:0006909 215 0.022
protein modification process GO:0036211 438 0.022
regulation of anatomical structure size GO:0090066 163 0.022
wing disc morphogenesis GO:0007472 344 0.022
oxoacid metabolic process GO:0043436 103 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
peripheral nervous system development GO:0007422 52 0.021
toll signaling pathway GO:0008063 25 0.021
programmed cell death GO:0012501 257 0.021
chromatin remodeling GO:0006338 72 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
positive regulation of innate immune response GO:0045089 38 0.021
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.020
regulation of developmental growth GO:0048638 174 0.020
regulation of localization GO:0032879 275 0.020
epithelial cell development GO:0002064 274 0.020
developmental growth GO:0048589 280 0.019
sensory perception of chemical stimulus GO:0007606 116 0.019
regulation of catabolic process GO:0009894 170 0.019
establishment of localization in cell GO:0051649 402 0.019
single organism intracellular transport GO:1902582 207 0.019
regulation of cell differentiation GO:0045595 302 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
cellular amine metabolic process GO:0044106 12 0.019
negative regulation of gene expression GO:0010629 387 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
lipid metabolic process GO:0006629 121 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
regulation of jnk cascade GO:0046328 40 0.018
Fly
ethanolamine containing compound metabolic process GO:0042439 4 0.018
organelle fission GO:0048285 340 0.018
regulation of programmed cell death GO:0043067 152 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
regulation of cell cycle process GO:0010564 181 0.018
pigmentation GO:0043473 75 0.018
nucleotide metabolic process GO:0009117 161 0.018
ras protein signal transduction GO:0007265 88 0.017
forebrain development GO:0030900 2 0.017
toxin metabolic process GO:0009404 2 0.017
cellular response to oxygen containing compound GO:1901701 79 0.017
Fly
epithelial cell migration GO:0010631 148 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
cellular ketone metabolic process GO:0042180 24 0.017
epithelial cell differentiation GO:0030855 322 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
regulation of secondary metabolic process GO:0043455 7 0.017
Fly
vitamin biosynthetic process GO:0009110 1 0.017
positive regulation of molecular function GO:0044093 136 0.017
regulation of behavior GO:0050795 75 0.017
chemotaxis GO:0006935 249 0.017
developmental programmed cell death GO:0010623 138 0.017
cellular lipid metabolic process GO:0044255 83 0.017
positive regulation of cellular amide metabolic process GO:0034250 26 0.017
Fly
organic substance transport GO:0071702 257 0.017
Fly
glycosyl compound metabolic process GO:1901657 127 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
regulation of autophagy GO:0010506 62 0.017
response to nutrient levels GO:0031667 114 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
Fly
death GO:0016265 284 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
gtp metabolic process GO:0046039 72 0.016
chromosome segregation GO:0007059 157 0.016
ovarian follicle cell development GO:0030707 248 0.016
organelle assembly GO:0070925 198 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
rna processing GO:0006396 147 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
regulation of protein localization GO:0032880 76 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
growth GO:0040007 359 0.016
regulation of protein metabolic process GO:0051246 256 0.016
response to copper ion GO:0046688 4 0.016
regulation of transport GO:0051049 181 0.016
amine metabolic process GO:0009308 12 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
intracellular transport GO:0046907 228 0.015
positive regulation of melanization defense response GO:0035008 1 0.015
response to hexose GO:0009746 3 0.015
developmental maturation GO:0021700 172 0.015
exocrine system development GO:0035272 162 0.015
response to radiation GO:0009314 155 0.015
salivary gland development GO:0007431 162 0.015
response to molecule of bacterial origin GO:0002237 7 0.015
Fly
nuclear division GO:0000280 332 0.015
synaptic transmission GO:0007268 288 0.015
acylglycerol biosynthetic process GO:0046463 2 0.015
blastoderm segmentation GO:0007350 159 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
eye development GO:0001654 323 0.015
cell cycle phase transition GO:0044770 140 0.015
neuron projection guidance GO:0097485 241 0.015
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.015
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
stem cell differentiation GO:0048863 117 0.015
regulation of cell death GO:0010941 173 0.015
negative regulation of mapk cascade GO:0043409 23 0.015
Fly
neuron recognition GO:0008038 101 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
eye pigmentation GO:0048069 43 0.015
cytolysis in other organism GO:0051715 1 0.015
alpha amino acid metabolic process GO:1901605 20 0.014
localization of cell GO:0051674 257 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
triglyceride biosynthetic process GO:0019432 2 0.014
segmentation GO:0035282 207 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
cell migration GO:0016477 238 0.014
regulation of molecular function GO:0065009 217 0.014
protein transport GO:0015031 155 0.014
regulation of gtpase activity GO:0043087 44 0.014
peptide biosynthetic process GO:0043043 42 0.014
Fly
cell projection assembly GO:0030031 94 0.014
autophagy GO:0006914 108 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
mitotic nuclear division GO:0007067 213 0.014
peptide metabolic process GO:0006518 80 0.014
Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
cellular response to radiation GO:0071478 52 0.014
regulation of apoptotic process GO:0042981 130 0.014
gland development GO:0048732 191 0.014
macromolecular complex assembly GO:0065003 256 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
telencephalon development GO:0021537 2 0.014
insecticide metabolic process GO:0017143 2 0.014
negative regulation of cell cycle GO:0045786 116 0.014
aromatic compound catabolic process GO:0019439 166 0.014
carbohydrate metabolic process GO:0005975 82 0.013
cell motility GO:0048870 251 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
anion homeostasis GO:0055081 3 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
gland morphogenesis GO:0022612 145 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
organophosphate catabolic process GO:0046434 112 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
non sensory hair organization GO:0035316 47 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
response to extracellular stimulus GO:0009991 116 0.013
ovarian follicle cell migration GO:0007297 121 0.013
axon guidance GO:0007411 233 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
cell aging GO:0007569 2 0.013
single organism cellular localization GO:1902580 180 0.013
response to lipid GO:0033993 38 0.013
Fly
regulation of tube architecture open tracheal system GO:0035152 68 0.013
salivary gland morphogenesis GO:0007435 145 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
multi multicellular organism process GO:0044706 123 0.013
heterocycle catabolic process GO:0046700 166 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
hindbrain development GO:0030902 2 0.013
xenobiotic catabolic process GO:0042178 1 0.013
axon development GO:0061564 297 0.012
hemocyte migration GO:0035099 19 0.012
photoreceptor cell development GO:0042461 96 0.012
establishment of protein localization GO:0045184 163 0.012
response to glucose GO:0009749 2 0.012
regulation of nervous system development GO:0051960 248 0.012
embryonic pattern specification GO:0009880 174 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
nucleoside metabolic process GO:0009116 127 0.012
female meiotic division GO:0007143 70 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
hematopoietic or lymphoid organ development GO:0048534 57 0.012
organelle localization GO:0051640 148 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
cellular macromolecule localization GO:0070727 220 0.012
protein localization GO:0008104 284 0.012
tissue migration GO:0090130 155 0.012
response to monosaccharide GO:0034284 4 0.012
biological adhesion GO:0022610 138 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
molting cycle process GO:0022404 29 0.012
eye pigment biosynthetic process GO:0006726 32 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
response to alcohol GO:0097305 95 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
synapse assembly GO:0007416 143 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
memory GO:0007613 94 0.012
limb development GO:0060173 1 0.012
purine containing compound catabolic process GO:0072523 112 0.011
regulation of phosphorylation GO:0042325 147 0.011
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of lipid transport GO:0032368 3 0.011
detection of stimulus GO:0051606 156 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
protein complex biogenesis GO:0070271 201 0.011
retina development in camera type eye GO:0060041 4 0.011
circadian behavior GO:0048512 76 0.011
proteolysis GO:0006508 192 0.011
respiratory system development GO:0060541 213 0.011
border follicle cell migration GO:0007298 113 0.011
immune system development GO:0002520 57 0.011
positive regulation of catabolic process GO:0009896 105 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
cellular response to organic substance GO:0071310 132 0.011
Fly
positive regulation of cell motility GO:2000147 3 0.011
endomembrane system organization GO:0010256 119 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
regulation of gene silencing GO:0060968 63 0.011
kidney development GO:0001822 3 0.011
rho protein signal transduction GO:0007266 14 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
taxis GO:0042330 304 0.011
autophagic cell death GO:0048102 83 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
cellular biogenic amine catabolic process GO:0042402 1 0.011
vitamin metabolic process GO:0006766 2 0.011
lateral inhibition GO:0046331 206 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
gtp catabolic process GO:0006184 72 0.011
dorsal ventral axis specification GO:0009950 66 0.011
rhythmic behavior GO:0007622 76 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
endodermal cell differentiation GO:0035987 3 0.011
mitotic spindle organization GO:0007052 220 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
response to wounding GO:0009611 94 0.011
response to organic cyclic compound GO:0014070 89 0.011
positive regulation of developmental process GO:0051094 143 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
dendrite morphogenesis GO:0048813 199 0.011
long term memory GO:0007616 62 0.011
gene silencing GO:0016458 138 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.010
meiotic cell cycle GO:0051321 171 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
lipid biosynthetic process GO:0008610 46 0.010
eye antennal disc development GO:0035214 60 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
negative regulation of phosphorus metabolic process GO:0010563 45 0.010
Fly
protein complex assembly GO:0006461 200 0.010
acetylcholine metabolic process GO:0008291 2 0.010
digestive tract morphogenesis GO:0048546 127 0.010
epithelium migration GO:0090132 148 0.010
kidney morphogenesis GO:0060993 3 0.010
nucleoside catabolic process GO:0009164 112 0.010
cellular homeostasis GO:0019725 80 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
digestive tract development GO:0048565 149 0.010
regulation of hydrolase activity GO:0051336 97 0.010
imaginal disc pattern formation GO:0007447 91 0.010
compound eye retinal cell programmed cell death GO:0046667 23 0.010
homeostatic process GO:0042592 199 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
regulation of rna splicing GO:0043484 69 0.010
positive regulation of lipid storage GO:0010884 4 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
oxidation reduction process GO:0055114 123 0.010
rhythmic process GO:0048511 106 0.010
adult behavior GO:0030534 137 0.010

PGRP-LB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
nervous system disease DOID:863 0 0.017
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013
cardiovascular system disease DOID:1287 0 0.013
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.011