Drosophila melanogaster

28 known processes

Kul (Dmel_CG1964)

Kuzbanian-like

(Aliases: ADAM10,CG1964,Dmel\CG1964,CT3146)

Kul biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of organ morphogenesis GO:2000027 78 0.254
regulation of multicellular organismal development GO:2000026 414 0.197
morphogenesis of a polarized epithelium GO:0001738 93 0.144
establishment of planar polarity GO:0001736 87 0.108
regulation of establishment of planar polarity GO:0090175 22 0.103
cell recognition GO:0008037 102 0.087
catabolic process GO:0009056 409 0.086
triglyceride catabolic process GO:0019433 3 0.083
cellular catabolic process GO:0044248 372 0.081
regulation of anatomical structure morphogenesis GO:0022603 242 0.080
wing disc morphogenesis GO:0007472 344 0.079
establishment of tissue polarity GO:0007164 87 0.070
posttranscriptional regulation of gene expression GO:0010608 145 0.062
imaginal disc derived appendage development GO:0048737 399 0.061
regionalization GO:0003002 416 0.061
appendage morphogenesis GO:0035107 397 0.060
appendage development GO:0048736 401 0.059
gene silencing by rna GO:0031047 57 0.056
organic substance catabolic process GO:1901575 308 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.055
phagocytosis GO:0006909 215 0.054
negative regulation of gene expression GO:0010629 387 0.053
embryonic pattern specification GO:0009880 174 0.053
neuron recognition GO:0008038 101 0.052
skeletal muscle organ development GO:0060538 48 0.052
forebrain development GO:0030900 2 0.052
segmentation GO:0035282 207 0.048
acylglycerol catabolic process GO:0046464 3 0.046
morphogenesis of an epithelium GO:0002009 276 0.046
imaginal disc derived wing hair organization GO:0035317 45 0.045
salivary gland morphogenesis GO:0007435 145 0.045
taxis GO:0042330 304 0.045
regulation of cell cycle GO:0051726 291 0.045
imaginal disc derived appendage morphogenesis GO:0035114 395 0.045
positive regulation of macromolecule metabolic process GO:0010604 405 0.044
regulation of cellular protein metabolic process GO:0032268 243 0.043
regulation of localization GO:0032879 275 0.042
developmental maturation GO:0021700 172 0.040
brain development GO:0007420 120 0.040
mitotic cell cycle phase transition GO:0044772 138 0.040
central nervous system development GO:0007417 201 0.039
negative regulation of signaling GO:0023057 219 0.039
regulation of protein metabolic process GO:0051246 256 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.038
organonitrogen compound metabolic process GO:1901564 318 0.037
regulation of cell differentiation GO:0045595 302 0.037
positive regulation of rna metabolic process GO:0051254 271 0.036
ethanolamine containing compound metabolic process GO:0042439 4 0.036
cell division GO:0051301 248 0.036
blastoderm segmentation GO:0007350 159 0.036
regulation of gene expression epigenetic GO:0040029 128 0.036
response to oxygen containing compound GO:1901700 200 0.035
posttranscriptional gene silencing GO:0016441 46 0.035
endocytosis GO:0006897 310 0.035
negative regulation of signal transduction GO:0009968 206 0.033
death GO:0016265 284 0.033
head development GO:0060322 135 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
compound eye photoreceptor cell differentiation GO:0001751 140 0.032
gene silencing GO:0016458 138 0.032
tissue morphogenesis GO:0048729 297 0.032
cell proliferation GO:0008283 299 0.031
phosphorylation GO:0016310 294 0.031
phospholipid homeostasis GO:0055091 1 0.031
regulation of nervous system development GO:0051960 248 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
cell cycle phase transition GO:0044770 140 0.031
single organism biosynthetic process GO:0044711 206 0.031
negative regulation of cell communication GO:0010648 223 0.031
regulation of mitotic cell cycle GO:0007346 190 0.030
metal ion transport GO:0030001 74 0.030
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
response to organophosphorus GO:0046683 2 0.029
positive regulation of protein metabolic process GO:0051247 128 0.028
macromolecule catabolic process GO:0009057 161 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
negative regulation of response to stimulus GO:0048585 258 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
positive regulation of gene expression GO:0010628 290 0.027
molting cycle GO:0042303 56 0.027
positive regulation of cell migration GO:0030335 2 0.027
regulation of organelle organization GO:0033043 196 0.027
axon development GO:0061564 297 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.026
oocyte development GO:0048599 124 0.026
maintenance of location GO:0051235 73 0.026
glycerolipid catabolic process GO:0046503 3 0.025
organelle fission GO:0048285 340 0.025
gland morphogenesis GO:0022612 145 0.025
salivary gland development GO:0007431 162 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
regulation of sequestering of triglyceride GO:0010889 3 0.025
organophosphate metabolic process GO:0019637 195 0.024
response to organic substance GO:0010033 284 0.024
anterior posterior pattern specification GO:0009952 136 0.024
apoptotic process GO:0006915 159 0.024
response to nitrogen compound GO:1901698 90 0.024
cell motility GO:0048870 251 0.024
localization of cell GO:0051674 257 0.024
developmental growth GO:0048589 280 0.024
regulation of transport GO:0051049 181 0.023
neuron projection guidance GO:0097485 241 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
regulation of synapse structure and activity GO:0050803 128 0.023
vesicle mediated transport GO:0016192 381 0.023
programmed cell death GO:0012501 257 0.023
body morphogenesis GO:0010171 2 0.023
regulation of proteolysis GO:0030162 87 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
regulation of embryonic development GO:0045995 68 0.022
photoreceptor cell differentiation GO:0046530 170 0.022
regulation of cell cycle process GO:0010564 181 0.021
cholesterol homeostasis GO:0042632 3 0.021
regulation of cell proliferation GO:0042127 163 0.021
regulation of cellular component biogenesis GO:0044087 201 0.021
positive regulation of signaling GO:0023056 243 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
chemotaxis GO:0006935 249 0.021
larval development GO:0002164 104 0.021
proteolysis GO:0006508 192 0.021
ion homeostasis GO:0050801 55 0.021
regulation of catabolic process GO:0009894 170 0.020
organic substance transport GO:0071702 257 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
smoothened signaling pathway GO:0007224 49 0.020
embryonic development via the syncytial blastoderm GO:0001700 148 0.020
cellular response to chemical stimulus GO:0070887 199 0.019
immune response activating signal transduction GO:0002757 2 0.019
proteoglycan biosynthetic process GO:0030166 10 0.019
response to temperature stimulus GO:0009266 106 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
regulation of cell death GO:0010941 173 0.019
hindbrain development GO:0030902 2 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
regulation of cell development GO:0060284 215 0.019
growth GO:0040007 359 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
positive regulation of cell motility GO:2000147 3 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
cell death GO:0008219 279 0.018
response to abiotic stimulus GO:0009628 341 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
aromatic compound catabolic process GO:0019439 166 0.018
muscle organ development GO:0007517 127 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
single organism catabolic process GO:0044712 228 0.018
response to copper ion GO:0046688 4 0.018
sterol homeostasis GO:0055092 4 0.018
cellular response to organic substance GO:0071310 132 0.018
positive regulation of catabolic process GO:0009896 105 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
long term memory GO:0007616 62 0.017
regulation of stem cell proliferation GO:0072091 40 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
immune response regulating signaling pathway GO:0002764 2 0.017
positive regulation of sequestering of triglyceride GO:0010890 1 0.017
cellular protein catabolic process GO:0044257 83 0.017
axonogenesis GO:0007409 290 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
nuclear division GO:0000280 332 0.017
embryonic axis specification GO:0000578 107 0.017
regulation of mrna processing GO:0050684 71 0.017
lipid storage GO:0019915 38 0.017
cellular protein modification process GO:0006464 438 0.017
telencephalon development GO:0021537 2 0.017
axon guidance GO:0007411 233 0.016
axis specification GO:0009798 167 0.016
posttranscriptional gene silencing by rna GO:0035194 45 0.016
regulation of apoptotic process GO:0042981 130 0.016
muscle structure development GO:0061061 224 0.016
response to organonitrogen compound GO:0010243 75 0.016
gene silencing by mirna GO:0035195 22 0.016
organelle localization GO:0051640 148 0.016
nephron development GO:0072006 3 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
neutral lipid biosynthetic process GO:0046460 2 0.016
small molecule metabolic process GO:0044281 305 0.016
sulfur compound metabolic process GO:0006790 59 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
positive regulation of cell communication GO:0010647 250 0.016
protein complex assembly GO:0006461 200 0.016
exocrine system development GO:0035272 162 0.016
mitotic nuclear division GO:0007067 213 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
tripartite regional subdivision GO:0007351 103 0.016
phosphatidylethanolamine metabolic process GO:0046337 1 0.015
regulation of neurogenesis GO:0050767 158 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
compound eye development GO:0048749 307 0.015
establishment of localization in cell GO:0051649 402 0.015
organic acid metabolic process GO:0006082 103 0.015
connective tissue development GO:0061448 3 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
camera type eye development GO:0043010 4 0.015
cellular lipid metabolic process GO:0044255 83 0.015
regulation of sterol transport GO:0032371 1 0.015
gland development GO:0048732 191 0.015
notch signaling pathway GO:0007219 120 0.015
mrna metabolic process GO:0016071 124 0.015
actin cytoskeleton organization GO:0030036 206 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.014
single organism intracellular transport GO:1902582 207 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
memory GO:0007613 94 0.014
regulation of anatomical structure size GO:0090066 163 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
negative regulation of cell cycle GO:0045786 116 0.014
regulation of molecular function GO:0065009 217 0.014
neurological system process GO:0050877 358 0.014
heterocycle catabolic process GO:0046700 166 0.014
cellular modified amino acid metabolic process GO:0006575 45 0.014
positive regulation of signal transduction GO:0009967 223 0.014
anterior posterior axis specification GO:0009948 109 0.014
amine metabolic process GO:0009308 12 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
epithelial cell differentiation GO:0030855 322 0.014
cell migration GO:0016477 238 0.014
eye morphogenesis GO:0048592 260 0.014
synaptic target recognition GO:0008039 45 0.014
rna processing GO:0006396 147 0.014
organic hydroxy compound metabolic process GO:1901615 83 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
organophosphate catabolic process GO:0046434 112 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
learning or memory GO:0007611 141 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
chitin based cuticle development GO:0040003 49 0.013
protein modification process GO:0036211 438 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
mesodermal cell fate specification GO:0007501 2 0.013
stem cell differentiation GO:0048863 117 0.013
regulation of translation GO:0006417 56 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
reproductive system development GO:0061458 74 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
intracellular transport GO:0046907 228 0.013
actin filament based process GO:0030029 220 0.013
wnt signaling pathway GO:0016055 98 0.013
positive regulation of lipid storage GO:0010884 4 0.012
endodermal cell differentiation GO:0035987 3 0.012
regulation of lipid transport GO:0032368 3 0.012
macromolecular complex assembly GO:0065003 256 0.012
cation transport GO:0006812 110 0.012
embryonic organ development GO:0048568 50 0.012
dendrite morphogenesis GO:0048813 199 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
response to alcohol GO:0097305 95 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
compound eye morphogenesis GO:0001745 249 0.012
regulation of cholesterol transport GO:0032374 1 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
oxoacid metabolic process GO:0043436 103 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
detection of abiotic stimulus GO:0009582 66 0.012
neural precursor cell proliferation GO:0061351 75 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
intracellular signal transduction GO:0035556 300 0.012
single organism cellular localization GO:1902580 180 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
oocyte differentiation GO:0009994 145 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.012
negative regulation of developmental process GO:0051093 201 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
rhythmic process GO:0048511 106 0.012
skin development GO:0043588 65 0.012
retina development in camera type eye GO:0060041 4 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
phosphatidic acid metabolic process GO:0046473 1 0.011
response to hypoxia GO:0001666 53 0.011
neuron fate commitment GO:0048663 50 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
regulation of chromosome organization GO:0033044 64 0.011
positive regulation of developmental process GO:0051094 143 0.011
cellular macromolecule localization GO:0070727 220 0.011
convergent extension GO:0060026 2 0.011
lipid biosynthetic process GO:0008610 46 0.011
spermatogenesis GO:0007283 200 0.011
establishment of organelle localization GO:0051656 122 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
response to endogenous stimulus GO:0009719 119 0.011
regulation of cellular localization GO:0060341 136 0.011
endomembrane system organization GO:0010256 119 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
regulation of phosphorylation GO:0042325 147 0.011
neutral lipid catabolic process GO:0046461 3 0.011
epidermis development GO:0008544 65 0.011
cell junction assembly GO:0034329 42 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
chorion containing eggshell formation GO:0007304 105 0.011
mrna processing GO:0006397 104 0.011
instar larval development GO:0002168 55 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
camera type eye morphogenesis GO:0048593 2 0.010
immune system process GO:0002376 347 0.010
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
regulation of hydrolase activity GO:0051336 97 0.010
eye photoreceptor cell fate commitment GO:0042706 37 0.010
stem cell proliferation GO:0072089 88 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
protein localization GO:0008104 284 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
regulation of developmental growth GO:0048638 174 0.010
chaeta development GO:0022416 97 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
muscle cell differentiation GO:0042692 103 0.010
spinal cord development GO:0021510 1 0.010
nucleotide metabolic process GO:0009117 161 0.010
cell fate specification GO:0001708 71 0.010

Kul disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
disease of metabolism DOID:0014667 0 0.020
acquired metabolic disease DOID:0060158 0 0.020
familial lipoprotein lipase deficiency DOID:14118 0 0.019
familial hyperlipidemia DOID:1168 0 0.019
lipid metabolism disorder DOID:3146 0 0.019
inherited metabolic disorder DOID:655 0 0.019
carbohydrate metabolism disease DOID:0050013 0 0.018
familial combined hyperlipidemia DOID:13809 0 0.018
hair disease DOID:421 0 0.017
integumentary system disease DOID:16 0 0.017
glucose metabolism disease DOID:4194 0 0.016
diabetes mellitus DOID:9351 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
familial hypertriglyceridemia DOID:0050527 0 0.011