Drosophila melanogaster

26 known processes

mu2 (Dmel_CG1960)

mutator 2

(Aliases: MU2,cDNA D,CG1960,mu-2,mutator[2],Dmel\CG1960)

mu2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome cycle GO:0007098 137 0.219
dna metabolic process GO:0006259 227 0.094
centrosome duplication GO:0051298 121 0.078
chromosome organization GO:0051276 360 0.075
establishment of localization in cell GO:0051649 402 0.065
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.062
regulation of cell cycle GO:0051726 291 0.061
regulation of cell cycle process GO:0010564 181 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.058
protein localization GO:0008104 284 0.056
positive regulation of response to stimulus GO:0048584 323 0.044
organic substance transport GO:0071702 257 0.043
dna damage checkpoint GO:0000077 78 0.042
positive regulation of rna biosynthetic process GO:1902680 266 0.042
dna replication GO:0006260 48 0.042
mitotic sister chromatid segregation GO:0000070 87 0.041
regulation of anatomical structure morphogenesis GO:0022603 242 0.041
negative regulation of cell cycle GO:0045786 116 0.041
organelle fission GO:0048285 340 0.039
intracellular signal transduction GO:0035556 300 0.039
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.037
positive regulation of signaling GO:0023056 243 0.036
regulation of protein metabolic process GO:0051246 256 0.036
mitotic cell cycle checkpoint GO:0007093 88 0.036
macromolecule catabolic process GO:0009057 161 0.035
cellular catabolic process GO:0044248 372 0.034
cellular macromolecule localization GO:0070727 220 0.034
regulation of catalytic activity GO:0050790 185 0.034
positive regulation of gene expression GO:0010628 290 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.033
positive regulation of signal transduction GO:0009967 223 0.032
chromosome separation GO:0051304 42 0.032
chromosome segregation GO:0007059 157 0.032
regulation of catabolic process GO:0009894 170 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
growth GO:0040007 359 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
covalent chromatin modification GO:0016569 106 0.028
single organism biosynthetic process GO:0044711 206 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
regulation of molecular function GO:0065009 217 0.028
mitotic g2 m transition checkpoint GO:0044818 70 0.028
dna biosynthetic process GO:0071897 24 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
positive regulation of biosynthetic process GO:0009891 316 0.027
nuclear division GO:0000280 332 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.026
spindle organization GO:0007051 253 0.026
morphogenesis of an epithelium GO:0002009 276 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
mitotic spindle organization GO:0007052 220 0.024
proteolysis GO:0006508 192 0.024
nuclear dna replication GO:0033260 1 0.024
intracellular transport GO:0046907 228 0.024
positive regulation of cell communication GO:0010647 250 0.024
dna packaging GO:0006323 91 0.024
response to abiotic stimulus GO:0009628 341 0.024
negative regulation of biosynthetic process GO:0009890 277 0.023
regulation of phosphorylation GO:0042325 147 0.023
catabolic process GO:0009056 409 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
cell proliferation GO:0008283 299 0.023
positive regulation of mitotic cell cycle GO:0045931 34 0.022
negative regulation of cellular component organization GO:0051129 108 0.022
mitotic g2 dna damage checkpoint GO:0007095 69 0.022
sister chromatid segregation GO:0000819 92 0.022
mitotic dna damage checkpoint GO:0044773 74 0.022
centrosome organization GO:0051297 163 0.022
negative regulation of cell cycle process GO:0010948 109 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
single organism intracellular transport GO:1902582 207 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
dna repair GO:0006281 54 0.021
response to bacterium GO:0009617 198 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.020
organic substance catabolic process GO:1901575 308 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
regionalization GO:0003002 416 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
dna integrity checkpoint GO:0031570 81 0.020
ras protein signal transduction GO:0007265 88 0.019
cellular protein localization GO:0034613 160 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
endocytosis GO:0006897 310 0.019
mrna metabolic process GO:0016071 124 0.019
protein modification process GO:0036211 438 0.019
microtubule organizing center organization GO:0031023 168 0.019
body morphogenesis GO:0010171 2 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
chromatin organization GO:0006325 207 0.018
regulation of chromosome organization GO:0033044 64 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
protein dna complex assembly GO:0065004 63 0.018
stem cell differentiation GO:0048863 117 0.018
regulation of hydrolase activity GO:0051336 97 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
appendage development GO:0048736 401 0.017
phosphorylation GO:0016310 294 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
dephosphorylation GO:0016311 51 0.017
meiotic cell cycle GO:0051321 171 0.017
lateral inhibition GO:0046331 206 0.017
cell cycle phase transition GO:0044770 140 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
cell division GO:0051301 248 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
cell cycle dna replication GO:0044786 23 0.016
regulation of cell differentiation GO:0045595 302 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
meiosis i GO:0007127 59 0.016
single organism catabolic process GO:0044712 228 0.016
response to wounding GO:0009611 94 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
regulation of cell shape GO:0008360 113 0.016
respiratory system development GO:0060541 213 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
positive regulation of catabolic process GO:0009896 105 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of protein modification process GO:0031399 112 0.015
positive regulation of molecular function GO:0044093 136 0.015
female meiotic division GO:0007143 70 0.015
mitotic nuclear division GO:0007067 213 0.015
single organism membrane organization GO:0044802 93 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of cell division GO:0051302 72 0.015
single organism cellular localization GO:1902580 180 0.015
phagocytosis GO:0006909 215 0.014
protein dna complex subunit organization GO:0071824 86 0.014
protein transport GO:0015031 155 0.014
tube morphogenesis GO:0035239 191 0.014
meiotic cell cycle process GO:1903046 132 0.014
single organism behavior GO:0044708 391 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
meiotic chromosome segregation GO:0045132 59 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
cell death GO:0008219 279 0.014
response to biotic stimulus GO:0009607 294 0.014
regulation of chromatin modification GO:1903308 28 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
muscle organ development GO:0007517 127 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
mrna processing GO:0006397 104 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
aromatic compound catabolic process GO:0019439 166 0.013
cytoplasmic transport GO:0016482 130 0.013
positive regulation of cell cycle GO:0045787 43 0.013
meiotic nuclear division GO:0007126 151 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
regulation of response to stress GO:0080134 200 0.013
negative regulation of developmental process GO:0051093 201 0.013
protein localization to organelle GO:0033365 82 0.013
histone modification GO:0016570 106 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
nucleus organization GO:0006997 45 0.013
macromolecular complex assembly GO:0065003 256 0.013
death GO:0016265 284 0.012
mitotic sister chromatid separation GO:0051306 30 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.012
central nervous system development GO:0007417 201 0.012
protein phosphorylation GO:0006468 169 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
brain development GO:0007420 120 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
chromatin remodeling GO:0006338 72 0.012
regulation of microtubule based process GO:0032886 49 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
head development GO:0060322 135 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
vesicle mediated transport GO:0016192 381 0.012
regulation of transferase activity GO:0051338 58 0.012
gene silencing GO:0016458 138 0.012
membrane organization GO:0061024 112 0.012
wound healing GO:0042060 75 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
chemosensory behavior GO:0007635 106 0.011
chromosome condensation GO:0030261 41 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of dna metabolic process GO:0051052 34 0.011
defense response to other organism GO:0098542 225 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
establishment of protein localization GO:0045184 163 0.011
postreplication repair GO:0006301 2 0.011
defense response GO:0006952 300 0.011
protein targeting GO:0006605 64 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
negative regulation of signal transduction GO:0009968 206 0.011
programmed cell death GO:0012501 257 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
appendage morphogenesis GO:0035107 397 0.011
innate immune response GO:0045087 144 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
regulation of transcription by chromatin organization GO:0034401 3 0.010
regulation of mapk cascade GO:0043408 92 0.010
negative regulation of organelle organization GO:0010639 56 0.010
actin filament based process GO:0030029 220 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
cellular protein modification process GO:0006464 438 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
immune response GO:0006955 246 0.010
chromatin modification GO:0016568 147 0.010
epithelial cell differentiation GO:0030855 322 0.010
regulation of nuclear division GO:0051783 58 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010

mu2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
nervous system disease DOID:863 0 0.012