Drosophila melanogaster

73 known processes

Dmn (Dmel_CG8269)

Dynamitin

(Aliases: p50/dynamitin,l(2)k16109,p50,dDyn,dmn,CG8269,Dmel\CG8269,p50/Dmn,l(2)k16218,P50)

Dmn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
retrograde axon cargo transport GO:0008090 9 0.786
oocyte axis specification GO:0007309 108 0.674
oocyte development GO:0048599 124 0.573
vesicle mediated transport GO:0016192 381 0.425
actin cytoskeleton organization GO:0030036 206 0.395
actin filament based process GO:0030029 220 0.391
cellular macromolecule localization GO:0070727 220 0.363
microtubule based transport GO:0010970 42 0.256
regionalization GO:0003002 416 0.231
oocyte construction GO:0007308 112 0.204
protein localization GO:0008104 284 0.200
endocytosis GO:0006897 310 0.196
intracellular transport GO:0046907 228 0.191
establishment or maintenance of cell polarity GO:0007163 167 0.188
Worm
oocyte differentiation GO:0009994 145 0.186
photoreceptor cell differentiation GO:0046530 170 0.181
regulation of cell cycle GO:0051726 291 0.179
axon cargo transport GO:0008088 29 0.172
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.170
organelle fission GO:0048285 340 0.156
Worm
vesicle localization GO:0051648 55 0.143
cell maturation GO:0048469 144 0.141
pole plasm assembly GO:0007315 61 0.140
compound eye photoreceptor development GO:0042051 78 0.139
rna localization GO:0006403 115 0.132
rhabdomere development GO:0042052 38 0.131
pole plasm mrna localization GO:0019094 49 0.128
positive regulation of gene expression GO:0010628 290 0.124
organelle localization GO:0051640 148 0.121
axon development GO:0061564 297 0.120
positive regulation of signal transduction GO:0009967 223 0.117
regulation of localization GO:0032879 275 0.117
eye photoreceptor cell differentiation GO:0001754 145 0.113
epithelial cell differentiation GO:0030855 322 0.112
negative regulation of cellular component organization GO:0051129 108 0.110
morphogenesis of an epithelium GO:0002009 276 0.110
eye development GO:0001654 323 0.108
spindle organization GO:0007051 253 0.103
rna splicing via transesterification reactions GO:0000375 73 0.100
regulation of mitotic cell cycle GO:0007346 190 0.098
establishment of localization in cell GO:0051649 402 0.096
positive regulation of rna biosynthetic process GO:1902680 266 0.095
regulation of transport GO:0051049 181 0.092
positive regulation of rna metabolic process GO:0051254 271 0.092
positive regulation of response to stimulus GO:0048584 323 0.091
positive regulation of nucleic acid templated transcription GO:1903508 266 0.088
mitotic spindle organization GO:0007052 220 0.087
compound eye photoreceptor cell differentiation GO:0001751 140 0.086
phagocytosis GO:0006909 215 0.085
cell proliferation GO:0008283 299 0.082
positive regulation of transcription dna templated GO:0045893 266 0.080
pole plasm rna localization GO:0007316 52 0.079
germarium derived oocyte fate determination GO:0007294 26 0.079
positive regulation of macromolecule metabolic process GO:0010604 405 0.079
eye photoreceptor cell development GO:0042462 81 0.076
organelle assembly GO:0070925 198 0.074
spindle assembly GO:0051225 80 0.073
appendage development GO:0048736 401 0.073
establishment of organelle localization GO:0051656 122 0.070
Worm
negative regulation of gene expression GO:0010629 387 0.070
negative regulation of cell cycle GO:0045786 116 0.070
photoreceptor cell development GO:0042461 96 0.070
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.069
single organism cellular localization GO:1902580 180 0.067
Worm
g2 dna damage checkpoint GO:0031572 69 0.067
dorsal ventral pattern formation GO:0009953 133 0.067
mrna metabolic process GO:0016071 124 0.065
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.065
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.065
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.064
mrna processing GO:0006397 104 0.064
microtubule organizing center organization GO:0031023 168 0.063
establishment of vesicle localization GO:0051650 51 0.063
cellular protein complex assembly GO:0043623 71 0.062
transcription from rna polymerase ii promoter GO:0006366 368 0.062
rna processing GO:0006396 147 0.061
negative regulation of cell cycle process GO:0010948 109 0.060
rna splicing GO:0008380 83 0.059
developmental maturation GO:0021700 172 0.058
macromolecular complex assembly GO:0065003 256 0.058
ovarian follicle cell migration GO:0007297 121 0.057
positive regulation of signaling GO:0023056 243 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.055
protein complex biogenesis GO:0070271 201 0.054
positive regulation of cell communication GO:0010647 250 0.054
microtubule based movement GO:0007018 51 0.053
anterograde axon cargo transport GO:0008089 6 0.053
mitotic nuclear division GO:0007067 213 0.053
Worm
regulation of cellular component biogenesis GO:0044087 201 0.053
muscle structure development GO:0061061 224 0.052
body morphogenesis GO:0010171 2 0.052
organic substance transport GO:0071702 257 0.051
cellular protein localization GO:0034613 160 0.051
cell death GO:0008219 279 0.050
oocyte fate determination GO:0030716 27 0.050
alternative mrna splicing via spliceosome GO:0000380 60 0.050
establishment of nucleus localization GO:0040023 26 0.049
Worm
dendrite development GO:0016358 204 0.049
synaptic vesicle localization GO:0097479 53 0.046
pigmentation GO:0043473 75 0.045
enzyme linked receptor protein signaling pathway GO:0007167 179 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.044
columnar cuboidal epithelial cell development GO:0002066 249 0.044
oocyte microtubule cytoskeleton organization GO:0016325 35 0.044
oocyte dorsal ventral axis specification GO:0007310 34 0.044
cellular component assembly involved in morphogenesis GO:0010927 151 0.042
establishment of synaptic vesicle localization GO:0097480 50 0.042
negative regulation of translation GO:0017148 28 0.041
regulation of multicellular organismal development GO:2000026 414 0.041
dendrite morphogenesis GO:0048813 199 0.040
mitotic g2 dna damage checkpoint GO:0007095 69 0.040
cell division GO:0051301 248 0.040
appendage morphogenesis GO:0035107 397 0.039
compound eye development GO:0048749 307 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
signal transduction by phosphorylation GO:0023014 107 0.037
regulation of synapse organization GO:0050807 110 0.037
cytoskeleton dependent intracellular transport GO:0030705 44 0.036
germ line cyst formation GO:0048134 44 0.036
positive regulation of neurotransmitter transport GO:0051590 2 0.036
regulation of mrna metabolic process GO:1903311 72 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
secondary metabolic process GO:0019748 75 0.035
anterior posterior axis specification embryo GO:0008595 103 0.035
single organism intracellular transport GO:1902582 207 0.035
mitotic cell cycle checkpoint GO:0007093 88 0.035
programmed cell death GO:0012501 257 0.034
negative regulation of developmental growth GO:0048640 64 0.034
regulation of mapk cascade GO:0043408 92 0.034
regulation of synapse assembly GO:0051963 94 0.033
regulation of mrna splicing via spliceosome GO:0048024 64 0.033
chaeta development GO:0022416 97 0.033
meiotic cell cycle process GO:1903046 132 0.033
nuclear division GO:0000280 332 0.033
Worm
synaptic vesicle transport GO:0048489 50 0.033
response to temperature stimulus GO:0009266 106 0.033
cellular macromolecular complex assembly GO:0034622 153 0.032
protein modification process GO:0036211 438 0.032
negative regulation of cellular metabolic process GO:0031324 382 0.032
pole plasm oskar mrna localization GO:0045451 46 0.032
response to abiotic stimulus GO:0009628 341 0.031
axonogenesis GO:0007409 290 0.030
biological adhesion GO:0022610 138 0.030
establishment of rna localization GO:0051236 47 0.030
membrane organization GO:0061024 112 0.029
phenol containing compound metabolic process GO:0018958 57 0.029
regulation of neuron projection development GO:0010975 69 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
cellularization GO:0007349 90 0.029
notch signaling pathway GO:0007219 120 0.029
organic substance catabolic process GO:1901575 308 0.029
regulation of synapse structure and activity GO:0050803 128 0.028
positive regulation of biosynthetic process GO:0009891 316 0.028
regulation of nervous system development GO:0051960 248 0.027
anterior posterior axis specification GO:0009948 109 0.026
death GO:0016265 284 0.026
centrosome organization GO:0051297 163 0.026
response to heat GO:0009408 63 0.026
regulation of phosphate metabolic process GO:0019220 210 0.026
blastoderm segmentation GO:0007350 159 0.026
positive regulation of intracellular transport GO:0032388 42 0.025
positive regulation of hydrolase activity GO:0051345 78 0.025
ras protein signal transduction GO:0007265 88 0.025
regulation of actin filament depolymerization GO:0030834 3 0.025
modification dependent protein catabolic process GO:0019941 78 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.025
intracellular protein transport GO:0006886 104 0.024
rna transport GO:0050658 46 0.024
regulation of cell development GO:0060284 215 0.024
pigment metabolic process GO:0042440 84 0.024
positive regulation of transport GO:0051050 92 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
spermatogenesis GO:0007283 200 0.023
golgi to plasma membrane protein transport GO:0043001 8 0.023
cell cycle phase transition GO:0044770 140 0.023
cellular protein modification process GO:0006464 438 0.023
endomembrane system organization GO:0010256 119 0.023
heart process GO:0003015 37 0.023
negative regulation of mitotic cell cycle GO:0045930 109 0.022
male gamete generation GO:0048232 201 0.022
protein prenylation GO:0018342 3 0.022
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.022
cell type specific apoptotic process GO:0097285 38 0.022
tissue morphogenesis GO:0048729 297 0.021
maternal determination of anterior posterior axis embryo GO:0008358 74 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
regulation of mrna processing GO:0050684 71 0.021
regulation of intracellular transport GO:0032386 64 0.021
retrograde transport endosome to golgi GO:0042147 3 0.021
organophosphate catabolic process GO:0046434 112 0.021
ameboidal type cell migration GO:0001667 151 0.020
mitotic spindle elongation GO:0000022 81 0.020
germarium derived egg chamber formation GO:0007293 101 0.020
mapk cascade GO:0000165 107 0.020
protein localization to plasma membrane GO:0072659 13 0.020
axis specification GO:0009798 167 0.020
translation GO:0006412 69 0.019
regulation of cytoskeleton organization GO:0051493 89 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
regulation of dendrite development GO:0050773 37 0.019
regulation of programmed cell death GO:0043067 152 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
autophagic vacuole assembly GO:0000045 2 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
embryonic pattern specification GO:0009880 174 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
macromolecule catabolic process GO:0009057 161 0.018
regulation of pole plasm oskar mrna localization GO:0007317 27 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
protein phosphorylation GO:0006468 169 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
phosphorylation GO:0016310 294 0.018
wing disc morphogenesis GO:0007472 344 0.018
determination of adult lifespan GO:0008340 137 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.018
regulation of neurogenesis GO:0050767 158 0.018
regulation of nuclear division GO:0051783 58 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
spindle elongation GO:0051231 83 0.018
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.018
negative regulation of organelle organization GO:0010639 56 0.018
segmentation GO:0035282 207 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
negative regulation of signaling GO:0023057 219 0.017
regulation of protein complex assembly GO:0043254 42 0.017
cell fate determination GO:0001709 91 0.017
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.017
regulation of phosphorylation GO:0042325 147 0.017
regulation of neuron differentiation GO:0045664 103 0.017
dephosphorylation GO:0016311 51 0.017
cytoplasm organization GO:0007028 64 0.016
immune system process GO:0002376 347 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
Worm
ribonucleotide metabolic process GO:0009259 145 0.016
sensory organ morphogenesis GO:0090596 260 0.016
regulation of cell death GO:0010941 173 0.016
mrna splicing via spliceosome GO:0000398 73 0.016
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.016
synapse organization GO:0050808 196 0.016
regulation of rna splicing GO:0043484 69 0.016
protein transport GO:0015031 155 0.016
catabolic process GO:0009056 409 0.016
actin filament polymerization GO:0030041 27 0.016
head development GO:0060322 135 0.015
protein localization to organelle GO:0033365 82 0.015
genitalia development GO:0048806 26 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
tripartite regional subdivision GO:0007351 103 0.015
regulation of cell differentiation GO:0045595 302 0.015
regulation of cell projection organization GO:0031344 92 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
single organism membrane organization GO:0044802 93 0.015
regulation of cell cycle process GO:0010564 181 0.015
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.015
intracellular signal transduction GO:0035556 300 0.014
synaptic transmission GO:0007268 288 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
response to nutrient levels GO:0031667 114 0.014
cytokinesis GO:0000910 90 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
tissue death GO:0016271 102 0.014
atp metabolic process GO:0046034 49 0.014
pronuclear migration GO:0035046 4 0.014
Worm
imaginal disc pattern formation GO:0007447 91 0.014
anterior posterior pattern specification GO:0009952 136 0.014
heart development GO:0007507 82 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
establishment of mitochondrion localization GO:0051654 7 0.014
trna modification GO:0006400 2 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
oocyte anterior posterior axis specification GO:0007314 72 0.013
regulation of hydrolase activity GO:0051336 97 0.013
aging GO:0007568 143 0.013
optokinetic behavior GO:0007634 3 0.013
actin filament organization GO:0007015 126 0.013
nuclear migration GO:0007097 20 0.013
Worm
post embryonic appendage morphogenesis GO:0035120 385 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
regulation of locomotion GO:0040012 42 0.013
spermatid differentiation GO:0048515 114 0.013
cytoplasmic transport GO:0016482 130 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
regulation of molecular function GO:0065009 217 0.012
negative regulation of nervous system development GO:0051961 92 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.012
lateral inhibition GO:0046331 206 0.012
receptor mediated endocytosis GO:0006898 21 0.012
regulation of organelle organization GO:0033043 196 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
eye pigmentation GO:0048069 43 0.012
tissue migration GO:0090130 155 0.012
ovarian follicle cell development GO:0030707 248 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
establishment of protein localization GO:0045184 163 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
golgi vesicle transport GO:0048193 27 0.012
meiotic cell cycle GO:0051321 171 0.012
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
plasma membrane organization GO:0007009 26 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
endosomal vesicle fusion GO:0034058 4 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
response to organic substance GO:0010033 284 0.012
reproductive system development GO:0061458 74 0.012
cellular homeostasis GO:0019725 80 0.012
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.012
cellular response to dna damage stimulus GO:0006974 223 0.011
protein catabolic process GO:0030163 101 0.011
mrna transport GO:0051028 15 0.011
mrna cis splicing via spliceosome GO:0045292 1 0.011
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.011
negative regulation of neuron apoptotic process GO:0043524 14 0.011
nucleus localization GO:0051647 34 0.011
Worm
germarium derived oocyte differentiation GO:0030706 29 0.011
multi organism behavior GO:0051705 175 0.011
regulation of cell proliferation GO:0042127 163 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
defense response GO:0006952 300 0.011
compound eye morphogenesis GO:0001745 249 0.011
cellular cation homeostasis GO:0030003 38 0.011
intracellular mrna localization GO:0008298 66 0.011
regulation of growth GO:0040008 233 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
gland morphogenesis GO:0022612 145 0.011
chromosome organization GO:0051276 360 0.011
cellular response to organic substance GO:0071310 132 0.011
developmental growth GO:0048589 280 0.011
brain development GO:0007420 120 0.011
regulation of behavior GO:0050795 75 0.011
apoptotic process GO:0006915 159 0.011
regulation of protein localization GO:0032880 76 0.010
reproductive structure development GO:0048608 74 0.010
cellular ketone metabolic process GO:0042180 24 0.010
regulation of apoptotic process GO:0042981 130 0.010
response to biotic stimulus GO:0009607 294 0.010
larval development GO:0002164 104 0.010
chaeta morphogenesis GO:0008407 42 0.010
regulation of catalytic activity GO:0050790 185 0.010
regulation of erk1 and erk2 cascade GO:0070372 39 0.010
response to endogenous stimulus GO:0009719 119 0.010
synapse assembly GO:0007416 143 0.010
negative regulation of developmental process GO:0051093 201 0.010
endoplasmic reticulum organization GO:0007029 13 0.010

Dmn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.024
cardiovascular system disease DOID:1287 0 0.017