Drosophila melanogaster

117 known processes

Spargel (Dmel_CG9809)

CG9809 gene product from transcript CG9809-RB

(Aliases: CG9809,cg9809,Dmel\CG9809,Srl,dPGC,spargel)

Spargel biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.719
response to other organism GO:0051707 293 0.475
response to bacterium GO:0009617 198 0.390
response to biotic stimulus GO:0009607 294 0.354
multicellular organismal aging GO:0010259 140 0.345
aging GO:0007568 143 0.336
response to organonitrogen compound GO:0010243 75 0.312
establishment of localization in cell GO:0051649 402 0.287
chromatin organization GO:0006325 207 0.262
defense response to bacterium GO:0042742 178 0.184
immune effector process GO:0002252 98 0.179
cellular response to endogenous stimulus GO:0071495 80 0.172
chromosome organization GO:0051276 360 0.169
programmed cell death GO:0012501 257 0.165
immune system process GO:0002376 347 0.159
response to peptide hormone GO:0043434 29 0.155
homeostatic process GO:0042592 199 0.140
regulation of growth GO:0040008 233 0.135
response to endogenous stimulus GO:0009719 119 0.125
response to starvation GO:0042594 97 0.124
negative regulation of cell communication GO:0010648 223 0.120
organic hydroxy compound biosynthetic process GO:1901617 21 0.117
nucleocytoplasmic transport GO:0006913 72 0.113
single organism biosynthetic process GO:0044711 206 0.105
response to nutrient levels GO:0031667 114 0.104
catabolic process GO:0009056 409 0.099
negative regulation of programmed cell death GO:0043069 72 0.094
cell death GO:0008219 279 0.091
growth GO:0040007 359 0.087
autophagy GO:0006914 108 0.086
cellular catabolic process GO:0044248 372 0.081
defense response to other organism GO:0098542 225 0.081
intracellular transport GO:0046907 228 0.078
camera type eye development GO:0043010 4 0.077
response to external biotic stimulus GO:0043207 293 0.076
establishment of ommatidial planar polarity GO:0042067 49 0.075
positive regulation of developmental process GO:0051094 143 0.074
cytoplasmic transport GO:0016482 130 0.073
protein transport GO:0015031 155 0.071
triglyceride metabolic process GO:0006641 12 0.070
immune response GO:0006955 246 0.070
regulation of cell growth GO:0001558 43 0.070
reactive oxygen species metabolic process GO:0072593 22 0.069
apoptotic process GO:0006915 159 0.066
organic substance transport GO:0071702 257 0.065
apoptotic signaling pathway GO:0097190 27 0.064
cellular response to organic substance GO:0071310 132 0.063
cellular response to extracellular stimulus GO:0031668 64 0.061
dna metabolic process GO:0006259 227 0.060
cellular lipid metabolic process GO:0044255 83 0.059
cellular macromolecule localization GO:0070727 220 0.059
cellular response to nutrient levels GO:0031669 62 0.057
positive regulation of immune response GO:0050778 63 0.057
defense response GO:0006952 300 0.056
cellular response to hormone stimulus GO:0032870 44 0.055
macromolecule catabolic process GO:0009057 161 0.054
regulation of immune system process GO:0002682 176 0.054
oxoacid metabolic process GO:0043436 103 0.053
regulation of tor signaling GO:0032006 21 0.052
positive regulation of immune system process GO:0002684 68 0.051
regulation of cell proliferation GO:0042127 163 0.050
negative regulation of signaling GO:0023057 219 0.049
response to extracellular stimulus GO:0009991 116 0.049
regulation of programmed cell death GO:0043067 152 0.048
embryo development ending in birth or egg hatching GO:0009792 152 0.045
regionalization GO:0003002 416 0.044
lipid biosynthetic process GO:0008610 46 0.044
cellular response to starvation GO:0009267 61 0.043
protein modification process GO:0036211 438 0.042
establishment of protein localization GO:0045184 163 0.042
response to nitrogen compound GO:1901698 90 0.042
cell proliferation GO:0008283 299 0.041
cardiovascular system development GO:0072358 82 0.041
regulation of cell cycle GO:0051726 291 0.041
establishment or maintenance of cell polarity GO:0007163 167 0.041
response to organic substance GO:0010033 284 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.040
vesicle mediated transport GO:0016192 381 0.039
organonitrogen compound biosynthetic process GO:1901566 117 0.038
regulation of cell death GO:0010941 173 0.037
phagocytosis GO:0006909 215 0.035
regulation of anatomical structure size GO:0090066 163 0.035
lipid metabolic process GO:0006629 121 0.034
multi organism behavior GO:0051705 175 0.033
epithelial cell differentiation GO:0030855 322 0.032
atp metabolic process GO:0046034 49 0.032
endocytosis GO:0006897 310 0.032
oxidation reduction process GO:0055114 123 0.032
eye morphogenesis GO:0048592 260 0.031
innate immune response GO:0045087 144 0.031
single organism intracellular transport GO:1902582 207 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.030
regulation of cellular component size GO:0032535 98 0.030
negative regulation of intracellular signal transduction GO:1902532 57 0.030
circadian rhythm GO:0007623 105 0.029
carbohydrate metabolic process GO:0005975 82 0.029
cellular response to insulin stimulus GO:0032869 28 0.029
death GO:0016265 284 0.028
interspecies interaction between organisms GO:0044419 16 0.028
response to hormone GO:0009725 45 0.028
hemopoiesis GO:0030097 46 0.027
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.027
immune response regulating signaling pathway GO:0002764 2 0.027
regulation of cell differentiation GO:0045595 302 0.027
regulation of developmental growth GO:0048638 174 0.027
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.026
positive regulation of response to stimulus GO:0048584 323 0.025
cell growth GO:0016049 108 0.025
tissue migration GO:0090130 155 0.025
regulation of cytoplasmic transport GO:1903649 47 0.025
response to insulin GO:0032868 29 0.025
energy derivation by oxidation of organic compounds GO:0015980 32 0.025
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.024
enzyme linked receptor protein signaling pathway GO:0007167 179 0.024
cellular response to nitrogen compound GO:1901699 51 0.024
intracellular mrna localization GO:0008298 66 0.024
segmentation GO:0035282 207 0.024
nuclear export GO:0051168 24 0.023
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.023
purine nucleoside monophosphate metabolic process GO:0009126 50 0.023
protein localization GO:0008104 284 0.022
forebrain development GO:0030900 2 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
organic substance catabolic process GO:1901575 308 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
response to oxidative stress GO:0006979 86 0.022
cellular protein localization GO:0034613 160 0.022
generation of precursor metabolites and energy GO:0006091 42 0.022
cellular response to molecule of bacterial origin GO:0071219 3 0.021
single organism catabolic process GO:0044712 228 0.021
chromatin modification GO:0016568 147 0.021
single organism cellular localization GO:1902580 180 0.021
phosphatidylcholine metabolic process GO:0046470 3 0.021
glycerolipid metabolic process GO:0046486 34 0.020
small molecule metabolic process GO:0044281 305 0.020
regulation of apoptotic process GO:0042981 130 0.020
mitotic dna damage checkpoint GO:0044773 74 0.019
regulation of multicellular organism growth GO:0040014 40 0.019
nucleoside catabolic process GO:0009164 112 0.019
regulation of cellular response to insulin stimulus GO:1900076 17 0.019
cellular protein complex assembly GO:0043623 71 0.019
intracellular protein transport GO:0006886 104 0.019
histone modification GO:0016570 106 0.019
regulation of lipid metabolic process GO:0019216 15 0.019
regulation of nucleocytoplasmic transport GO:0046822 35 0.019
connective tissue development GO:0061448 3 0.019
regulation of intracellular protein transport GO:0033157 46 0.019
hematopoietic or lymphoid organ development GO:0048534 57 0.018
ribonucleoside monophosphate metabolic process GO:0009161 51 0.018
positive regulation of multicellular organism growth GO:0040018 21 0.018
regulation of cell size GO:0008361 63 0.018
cellular response to oxygen containing compound GO:1901701 79 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
cellular protein modification process GO:0006464 438 0.018
immune system development GO:0002520 57 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
positive regulation of cell growth GO:0030307 19 0.017
regulation of intracellular transport GO:0032386 64 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
single organismal cell cell adhesion GO:0016337 45 0.017
negative regulation of cell proliferation GO:0008285 69 0.017
regulation of catabolic process GO:0009894 170 0.017
positive regulation of signaling GO:0023056 243 0.017
ovarian follicle cell development GO:0030707 248 0.017
acylglycerol metabolic process GO:0006639 12 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.016
circulatory system development GO:0072359 82 0.016
organic acid metabolic process GO:0006082 103 0.016
response to oxygen containing compound GO:1901700 200 0.016
stem cell maintenance GO:0019827 67 0.016
negative regulation of growth GO:0045926 84 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.016
response to peptidoglycan GO:0032494 2 0.015
reproductive behavior GO:0019098 122 0.015
larval development GO:0002164 104 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
regulation of immune response GO:0050776 118 0.015
regulation of establishment of protein localization GO:0070201 61 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
protein ubiquitination GO:0016567 70 0.014
peptidyl lysine modification GO:0018205 57 0.014
cellular response to external stimulus GO:0071496 66 0.014
cellular response to peptide hormone stimulus GO:0071375 28 0.014
regulation of response to stress GO:0080134 200 0.014
humoral immune response GO:0006959 117 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.014
response to lipopolysaccharide GO:0032496 4 0.014
regulation of reactive oxygen species metabolic process GO:2000377 8 0.014
cellular calcium ion homeostasis GO:0006874 21 0.014
inositol lipid mediated signaling GO:0048017 4 0.014
tor signaling GO:0031929 32 0.014
response to peptide GO:1901652 29 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
regulation of protein complex assembly GO:0043254 42 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
response to organic cyclic compound GO:0014070 89 0.013
photoreceptor cell development GO:0042461 96 0.013
regulation of localization GO:0032879 275 0.013
regulation of lipid storage GO:0010883 22 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
cell migration GO:0016477 238 0.013
regulation of autophagy GO:0010506 62 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
sensory organ morphogenesis GO:0090596 260 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of protein transport GO:0051223 57 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
lipid modification GO:0030258 24 0.012
response to oxygen levels GO:0070482 59 0.012
regulation of molecular function GO:0065009 217 0.012
fatty acid metabolic process GO:0006631 20 0.012
purine ribonucleotide biosynthetic process GO:0009152 28 0.012
cellular homeostasis GO:0019725 80 0.012
positive regulation of cell death GO:0010942 69 0.012
cellular response to decreased oxygen levels GO:0036294 30 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
exocrine system development GO:0035272 162 0.012
telencephalon development GO:0021537 2 0.012
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.012
single organism nuclear import GO:1902593 51 0.011
small molecule biosynthetic process GO:0044283 37 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
appendage development GO:0048736 401 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.011
purine containing compound catabolic process GO:0072523 112 0.011
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.011
synaptic vesicle localization GO:0097479 53 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
heart development GO:0007507 82 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
maintenance of location GO:0051235 73 0.011
ribonucleotide biosynthetic process GO:0009260 28 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
cell type specific apoptotic process GO:0097285 38 0.011
lateral inhibition GO:0046331 206 0.011
epithelium migration GO:0090132 148 0.011
aromatic compound catabolic process GO:0019439 166 0.011
intracellular signal transduction GO:0035556 300 0.011
dna damage checkpoint GO:0000077 78 0.010
response to virus GO:0009615 28 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
negative regulation of signal transduction GO:0009968 206 0.010
nuclear transport GO:0051169 72 0.010
amine metabolic process GO:0009308 12 0.010
response to decreased oxygen levels GO:0036293 58 0.010
positive regulation of protein transport GO:0051222 37 0.010
cellular amine metabolic process GO:0044106 12 0.010
membrane organization GO:0061024 112 0.010

Spargel disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
disease of anatomical entity DOID:7 0 0.011