Drosophila melanogaster

0 known processes

c12.2 (Dmel_CG12149)

CG12149 gene product from transcript CG12149-RA

(Aliases: CG12149,Dmel\CG12149)

c12.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.074
organonitrogen compound metabolic process GO:1901564 318 0.066
oxoacid metabolic process GO:0043436 103 0.049
vesicle mediated transport GO:0016192 381 0.044
organic substance catabolic process GO:1901575 308 0.041
carboxylic acid metabolic process GO:0019752 92 0.041
single organism catabolic process GO:0044712 228 0.038
endocytosis GO:0006897 310 0.037
organic acid metabolic process GO:0006082 103 0.037
catabolic process GO:0009056 409 0.036
cellular catabolic process GO:0044248 372 0.036
protein modification process GO:0036211 438 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
establishment of localization in cell GO:0051649 402 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
regulation of localization GO:0032879 275 0.032
carbohydrate derivative metabolic process GO:1901135 217 0.032
phagocytosis GO:0006909 215 0.030
actin filament based process GO:0030029 220 0.030
intracellular signal transduction GO:0035556 300 0.030
nucleotide metabolic process GO:0009117 161 0.030
response to organic substance GO:0010033 284 0.030
cellular protein modification process GO:0006464 438 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
response to oxygen containing compound GO:1901700 200 0.029
organic substance transport GO:0071702 257 0.028
regulation of anatomical structure size GO:0090066 163 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
wing disc morphogenesis GO:0007472 344 0.028
response to abiotic stimulus GO:0009628 341 0.028
appendage morphogenesis GO:0035107 397 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
lipid metabolic process GO:0006629 121 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
appendage development GO:0048736 401 0.027
protein localization GO:0008104 284 0.027
response to organophosphorus GO:0046683 2 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
compound eye morphogenesis GO:0001745 249 0.025
compound eye development GO:0048749 307 0.025
steroid catabolic process GO:0006706 1 0.025
single organism biosynthetic process GO:0044711 206 0.025
androgen metabolic process GO:0008209 1 0.025
purine containing compound metabolic process GO:0072521 155 0.025
eye development GO:0001654 323 0.025
g protein coupled receptor signaling pathway GO:0007186 136 0.025
organophosphate metabolic process GO:0019637 195 0.024
eye morphogenesis GO:0048592 260 0.024
actin cytoskeleton organization GO:0030036 206 0.024
response to lipopolysaccharide GO:0032496 4 0.024
xenobiotic catabolic process GO:0042178 1 0.024
regulation of multicellular organismal development GO:2000026 414 0.023
positive regulation of signaling GO:0023056 243 0.023
forebrain development GO:0030900 2 0.023
anion homeostasis GO:0055081 3 0.023
epithelial cell development GO:0002064 274 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
single organism intracellular transport GO:1902582 207 0.023
body morphogenesis GO:0010171 2 0.023
negative regulation of gene expression GO:0010629 387 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
purine nucleoside metabolic process GO:0042278 127 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
phosphorylation GO:0016310 294 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
positive regulation of cell communication GO:0010647 250 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
response to nutrient levels GO:0031667 114 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
sensory organ morphogenesis GO:0090596 260 0.022
localization of cell GO:0051674 257 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
neurological system process GO:0050877 358 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
macromolecular complex assembly GO:0065003 256 0.021
response to bacterium GO:0009617 198 0.021
purine nucleoside triphosphate metabolic process GO:0009144 119 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
defense response GO:0006952 300 0.021
nucleoside metabolic process GO:0009116 127 0.021
intracellular transport GO:0046907 228 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
ribose phosphate metabolic process GO:0019693 145 0.020
death GO:0016265 284 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
ribonucleoside metabolic process GO:0009119 127 0.020
epithelial cell differentiation GO:0030855 322 0.020
regulation of transport GO:0051049 181 0.020
cell death GO:0008219 279 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
aromatic compound catabolic process GO:0019439 166 0.020
negative regulation of signaling GO:0023057 219 0.019
purine ribonucleoside metabolic process GO:0046128 127 0.019
regulation of cell differentiation GO:0045595 302 0.019
single organism behavior GO:0044708 391 0.019
positive regulation of gene expression GO:0010628 290 0.019
camera type eye development GO:0043010 4 0.019
response to other organism GO:0051707 293 0.019
hormone catabolic process GO:0042447 3 0.019
developmental growth GO:0048589 280 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
regulation of molecular function GO:0065009 217 0.019
negative regulation of cell communication GO:0010648 223 0.019
salivary gland development GO:0007431 162 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
protein transport GO:0015031 155 0.019
response to biotic stimulus GO:0009607 294 0.019
lateral inhibition GO:0046331 206 0.019
gland development GO:0048732 191 0.019
regulation of catalytic activity GO:0050790 185 0.019
glycosyl compound catabolic process GO:1901658 112 0.018
cellular ketone metabolic process GO:0042180 24 0.018
immune system process GO:0002376 347 0.018
heterocycle catabolic process GO:0046700 166 0.018
kidney development GO:0001822 3 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
immune response GO:0006955 246 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
regulation of cell cycle GO:0051726 291 0.018
actin filament organization GO:0007015 126 0.018
purine containing compound catabolic process GO:0072523 112 0.017
regionalization GO:0003002 416 0.017
positive regulation of signal transduction GO:0009967 223 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
negative regulation of signal transduction GO:0009968 206 0.017
connective tissue development GO:0061448 3 0.017
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
positive regulation of cell migration GO:0030335 2 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
homeostatic process GO:0042592 199 0.017
secretion by cell GO:0032940 101 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
tissue morphogenesis GO:0048729 297 0.016
nucleotide catabolic process GO:0009166 109 0.016
telencephalon development GO:0021537 2 0.016
secretion GO:0046903 109 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
respiratory system development GO:0060541 213 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
cellular lipid metabolic process GO:0044255 83 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
amine metabolic process GO:0009308 12 0.016
salivary gland morphogenesis GO:0007435 145 0.016
spindle organization GO:0007051 253 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
protein complex assembly GO:0006461 200 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
open tracheal system development GO:0007424 204 0.016
ion transport GO:0006811 145 0.016
multi organism behavior GO:0051705 175 0.016
response to extracellular stimulus GO:0009991 116 0.016
response to external biotic stimulus GO:0043207 293 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
cellular amine metabolic process GO:0044106 12 0.016
transmembrane transport GO:0055085 139 0.016
organelle assembly GO:0070925 198 0.015
ras protein signal transduction GO:0007265 88 0.015
exocrine system development GO:0035272 162 0.015
response to endogenous stimulus GO:0009719 119 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
programmed cell death GO:0012501 257 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
regulation of catabolic process GO:0009894 170 0.015
negative regulation of developmental process GO:0051093 201 0.015
cell motility GO:0048870 251 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
regulation of cell death GO:0010941 173 0.015
cellular macromolecule localization GO:0070727 220 0.015
positive regulation of cell motility GO:2000147 3 0.015
organelle fission GO:0048285 340 0.015
oxidation reduction process GO:0055114 123 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
organophosphate catabolic process GO:0046434 112 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
single organism cellular localization GO:1902580 180 0.015
rna processing GO:0006396 147 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
protein complex biogenesis GO:0070271 201 0.015
positive regulation of molecular function GO:0044093 136 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
regulation of programmed cell death GO:0043067 152 0.015
cellular response to organic substance GO:0071310 132 0.015
response to starvation GO:0042594 97 0.015
axon guidance GO:0007411 233 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
tube development GO:0035295 244 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
adult behavior GO:0030534 137 0.014
cell proliferation GO:0008283 299 0.014
aging GO:0007568 143 0.014
chemotaxis GO:0006935 249 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
protein phosphorylation GO:0006468 169 0.014
regulation of cell development GO:0060284 215 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
wnt signaling pathway GO:0016055 98 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
establishment of protein localization GO:0045184 163 0.014
mapk cascade GO:0000165 107 0.014
regulation of cellular localization GO:0060341 136 0.014
axonogenesis GO:0007409 290 0.013
membrane organization GO:0061024 112 0.013
regulation of response to stress GO:0080134 200 0.013
ovarian follicle cell development GO:0030707 248 0.013
regulation of organelle organization GO:0033043 196 0.013
growth GO:0040007 359 0.013
synapse organization GO:0050808 196 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
cellular response to ethanol GO:0071361 4 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
biological adhesion GO:0022610 138 0.013
digestive tract development GO:0048565 149 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
response to nitrogen compound GO:1901698 90 0.013
vitamin metabolic process GO:0006766 2 0.013
innate immune response GO:0045087 144 0.013
locomotory behavior GO:0007626 176 0.013
cell adhesion GO:0007155 136 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
single organism membrane organization GO:0044802 93 0.013
response to radiation GO:0009314 155 0.013
taxis GO:0042330 304 0.013
endomembrane system organization GO:0010256 119 0.013
vitamin biosynthetic process GO:0009110 1 0.013
cellular protein localization GO:0034613 160 0.012
nuclear division GO:0000280 332 0.012
chemical homeostasis GO:0048878 92 0.012
regulation of nervous system development GO:0051960 248 0.012
nucleoside catabolic process GO:0009164 112 0.012
synaptic transmission GO:0007268 288 0.012
response to copper ion GO:0046688 4 0.012
tube morphogenesis GO:0035239 191 0.012
axon development GO:0061564 297 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
response to temperature stimulus GO:0009266 106 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
dendrite development GO:0016358 204 0.012
regulation of protein metabolic process GO:0051246 256 0.012
response to organic cyclic compound GO:0014070 89 0.012
response to hexose GO:0009746 3 0.012
estrogen metabolic process GO:0008210 1 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
cell division GO:0051301 248 0.012
response to organonitrogen compound GO:0010243 75 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
response to alcohol GO:0097305 95 0.012
positive regulation of catabolic process GO:0009896 105 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
nephron development GO:0072006 3 0.012
regulation of growth GO:0040008 233 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
dendrite morphogenesis GO:0048813 199 0.012
regulation of immune system process GO:0002682 176 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
multi multicellular organism process GO:0044706 123 0.011
secondary metabolic process GO:0019748 75 0.011
central nervous system development GO:0007417 201 0.011
apoptotic process GO:0006915 159 0.011
detection of stimulus GO:0051606 156 0.011
immune response activating signal transduction GO:0002757 2 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
retina development in camera type eye GO:0060041 4 0.011
regulation of developmental growth GO:0048638 174 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
regulation of apoptotic process GO:0042981 130 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
gland morphogenesis GO:0022612 145 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
carbohydrate metabolic process GO:0005975 82 0.011
cytoplasmic transport GO:0016482 130 0.011
limb development GO:0060173 1 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
cell projection assembly GO:0030031 94 0.011
defense response to bacterium GO:0042742 178 0.011
response to glucose GO:0009749 2 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of phosphorylation GO:0042325 147 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
regulation of cell proliferation GO:0042127 163 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
regulation of hydrolase activity GO:0051336 97 0.011
negative regulation of cell cycle GO:0045786 116 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
developmental programmed cell death GO:0010623 138 0.011
regulation of protein localization GO:0032880 76 0.011
macromolecule catabolic process GO:0009057 161 0.011
autophagic cell death GO:0048102 83 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
cell cycle phase transition GO:0044770 140 0.011
digestive tract morphogenesis GO:0048546 127 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
wound healing GO:0042060 75 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
hindbrain development GO:0030902 2 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
mitotic spindle organization GO:0007052 220 0.010
ameboidal type cell migration GO:0001667 151 0.010
mrna metabolic process GO:0016071 124 0.010
cell migration GO:0016477 238 0.010
salivary gland histolysis GO:0035070 88 0.010
detection of chemical stimulus GO:0009593 93 0.010
photoreceptor cell development GO:0042461 96 0.010
intracellular protein transport GO:0006886 104 0.010
polyol biosynthetic process GO:0046173 3 0.010
cell fate determination GO:0001709 91 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
triglyceride biosynthetic process GO:0019432 2 0.010
cellular amide metabolic process GO:0043603 80 0.010
developmental maturation GO:0021700 172 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
gtp metabolic process GO:0046039 72 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
sensory perception of pain GO:0019233 4 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
humoral immune response GO:0006959 117 0.010
morphogenesis of a polarized epithelium GO:0001738 93 0.010
sulfur compound metabolic process GO:0006790 59 0.010

c12.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
nervous system disease DOID:863 0 0.028
cardiovascular system disease DOID:1287 0 0.021
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.018
sensory system disease DOID:0050155 0 0.014
vascular disease DOID:178 0 0.013
artery disease DOID:0050828 0 0.012
musculoskeletal system disease DOID:17 0 0.011
central nervous system disease DOID:331 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
essential hypertension DOID:10825 0 0.010
hypertension DOID:10763 0 0.010