Drosophila melanogaster

45 known processes

Tre (Dmel_CG15779)

Trehalose-sensitivity

(Aliases: Gr5,LU.7,GR5A,han,GrLU7,Dmel\CG15779,Dmel5a,CG15779,GRLU.7,tre,Gr5A1,Gr5a)

Tre biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of chemical stimulus GO:0007606 116 0.990
sensory perception GO:0007600 196 0.988
sensory perception of taste GO:0050909 25 0.988
single organism behavior GO:0044708 391 0.968
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.961
detection of disaccharide stimulus GO:0034288 1 0.878
Fly
sensory perception of sweet taste GO:0050916 14 0.830
neurological system process GO:0050877 358 0.821
response to insecticide GO:0017085 14 0.776
detection of chemical stimulus involved in sensory perception of sweet taste GO:0001582 11 0.667
sensory perception of salty taste GO:0050914 3 0.651
detection of monosaccharide stimulus GO:0034287 1 0.637
Fly
detection of stimulus GO:0051606 156 0.588
male courtship behavior GO:0008049 63 0.529
detection of chemical stimulus involved in sensory perception of taste GO:0050912 13 0.520
sensory perception of smell GO:0007608 80 0.509
detection of light stimulus GO:0009583 58 0.490
inter male aggressive behavior GO:0002121 60 0.430
response to monosaccharide GO:0034284 4 0.423
Fly
feeding behavior GO:0007631 50 0.386
cation transmembrane transport GO:0098655 88 0.370
response to toxic substance GO:0009636 22 0.358
phototransduction GO:0007602 52 0.340
male courtship behavior tapping to detect pheromone GO:0016544 1 0.316
detection of external stimulus GO:0009581 66 0.288
detection of maltose stimulus GO:0034289 1 0.285
Fly
response to temperature stimulus GO:0009266 106 0.282
detection of stimulus involved in sensory perception GO:0050906 92 0.255
pigment metabolic process GO:0042440 84 0.248
detection of chemical stimulus GO:0009593 93 0.226
detection of glucose GO:0051594 1 0.224
Fly
cation transport GO:0006812 110 0.217
response to glucose GO:0009749 2 0.210
Fly
detection of sucrose stimulus GO:0009731 1 0.184
Fly
male mating behavior GO:0060179 70 0.184
response to organic substance GO:0010033 284 0.181
adult behavior GO:0030534 137 0.179
multi organism behavior GO:0051705 175 0.175
calcium ion transport GO:0006816 24 0.165
reproductive behavior GO:0019098 122 0.148
mating GO:0007618 120 0.144
ion transmembrane transport GO:0034220 122 0.139
inorganic cation transmembrane transport GO:0098662 61 0.137
response to oxygen containing compound GO:1901700 200 0.133
response to radiation GO:0009314 155 0.127
inorganic ion transmembrane transport GO:0098660 73 0.121
negative regulation of cyclic nucleotide metabolic process GO:0030800 3 0.117
transmembrane transport GO:0055085 139 0.108
response to hexose GO:0009746 3 0.107
Fly
cyclic nucleotide metabolic process GO:0009187 28 0.098
courtship behavior GO:0007619 68 0.093
detection of abiotic stimulus GO:0009582 66 0.093
response to nutrient levels GO:0031667 114 0.090
ion transport GO:0006811 145 0.090
divalent inorganic cation transport GO:0072511 30 0.089
behavioral response to ethanol GO:0048149 49 0.089
protein complex biogenesis GO:0070271 201 0.089
response to abiotic stimulus GO:0009628 341 0.088
establishment of localization in cell GO:0051649 402 0.088
mating behavior GO:0007617 106 0.085
melanization defense response GO:0035006 45 0.085
response to alkaloid GO:0043279 26 0.081
chemical homeostasis GO:0048878 92 0.079
divalent metal ion transport GO:0070838 26 0.077
metal ion transport GO:0030001 74 0.076
axon cargo transport GO:0008088 29 0.075
detection of carbohydrate stimulus GO:0009730 1 0.074
Fly
detection of hexose stimulus GO:0009732 1 0.070
Fly
response to extracellular stimulus GO:0009991 116 0.069
behavioral response to nutrient GO:0051780 7 0.068
regulation of lyase activity GO:0051339 14 0.067
multi multicellular organism process GO:0044706 123 0.066
secondary metabolic process GO:0019748 75 0.066
cellular response to chemical stimulus GO:0070887 199 0.066
phototaxis GO:0042331 21 0.065
response to light stimulus GO:0009416 124 0.063
phenol containing compound metabolic process GO:0018958 57 0.063
homeostatic process GO:0042592 199 0.063
melanin metabolic process GO:0006582 47 0.062
salt aversion GO:0035199 3 0.059
sensory perception of mechanical stimulus GO:0050954 72 0.058
multicellular organismal reproductive behavior GO:0033057 110 0.057
single organism intracellular transport GO:1902582 207 0.056
protein complex assembly GO:0006461 200 0.055
response to organonitrogen compound GO:0010243 75 0.055
regulation of cellular localization GO:0060341 136 0.055
cyclic nucleotide biosynthetic process GO:0009190 25 0.052
chemosensory behavior GO:0007635 106 0.052
multi organism reproductive behavior GO:0044705 121 0.051
metal ion homeostasis GO:0055065 44 0.050
store operated calcium entry GO:0002115 3 0.050
olfactory behavior GO:0042048 97 0.050
cellular homeostasis GO:0019725 80 0.046
response to nitrogen compound GO:1901698 90 0.045
cell proliferation GO:0008283 299 0.045
nucleoside phosphate biosynthetic process GO:1901293 34 0.044
cell division GO:0051301 248 0.044
calcium ion transmembrane transport GO:0070588 17 0.044
organic hydroxy compound metabolic process GO:1901615 83 0.044
response to alcohol GO:0097305 95 0.043
learning GO:0007612 75 0.043
cellular response to oxygen containing compound GO:1901701 79 0.043
dendrite development GO:0016358 204 0.043
monovalent inorganic cation transport GO:0015672 40 0.042
regulation of transport GO:0051049 181 0.042
organonitrogen compound metabolic process GO:1901564 318 0.042
response to organic cyclic compound GO:0014070 89 0.041
synaptic transmission GO:0007268 288 0.041
response to biotic stimulus GO:0009607 294 0.041
protein heterooligomerization GO:0051291 4 0.040
ion homeostasis GO:0050801 55 0.040
taxis GO:0042330 304 0.039
cilium assembly GO:0042384 38 0.038
regulation of cell cycle GO:0051726 291 0.038
energy taxis GO:0009453 21 0.037
single organism biosynthetic process GO:0044711 206 0.037
negative regulation of multicellular organismal process GO:0051241 142 0.036
response to caffeine GO:0031000 12 0.035
response to other organism GO:0051707 293 0.034
cellular response to carbohydrate stimulus GO:0071322 4 0.034
carbohydrate derivative biosynthetic process GO:1901137 85 0.034
cation homeostasis GO:0055080 51 0.034
response to bacterium GO:0009617 198 0.032
organic substance catabolic process GO:1901575 308 0.032
cellular ion homeostasis GO:0006873 39 0.032
positive regulation of gene expression GO:0010628 290 0.032
intracellular transport GO:0046907 228 0.031
defense response to bacterium GO:0042742 178 0.031
response to ethanol GO:0045471 59 0.031
response to inorganic substance GO:0010035 44 0.030
regulation of synapse structure and activity GO:0050803 128 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
organic acid metabolic process GO:0006082 103 0.029
localization of cell GO:0051674 257 0.029
regulation of mitotic cell cycle GO:0007346 190 0.029
wound healing spreading of epidermal cells GO:0035313 1 0.029
dopamine receptor signaling pathway GO:0007212 4 0.028
macromolecular complex assembly GO:0065003 256 0.028
catabolic process GO:0009056 409 0.028
regulation of localization GO:0032879 275 0.027
regulation of cell cycle process GO:0010564 181 0.027
cellular metal ion homeostasis GO:0006875 31 0.027
regulation of ion transport GO:0043269 39 0.027
positive regulation of transport GO:0051050 92 0.027
cellular catabolic process GO:0044248 372 0.027
small molecule metabolic process GO:0044281 305 0.026
defense response to other organism GO:0098542 225 0.026
innate immune response GO:0045087 144 0.026
dendrite morphogenesis GO:0048813 199 0.025
cell migration GO:0016477 238 0.025
drinking behavior GO:0042756 2 0.025
synapse organization GO:0050808 196 0.025
single organism catabolic process GO:0044712 228 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
immune response GO:0006955 246 0.024
response to endogenous stimulus GO:0009719 119 0.024
gliogenesis GO:0042063 80 0.024
carboxylic acid metabolic process GO:0019752 92 0.023
maintenance of location GO:0051235 73 0.023
cellular response to hexose stimulus GO:0071331 1 0.023
regulation of reproductive process GO:2000241 54 0.023
response to external biotic stimulus GO:0043207 293 0.023
regulation of protein transport GO:0051223 57 0.023
reflex GO:0060004 6 0.023
adult locomotory behavior GO:0008344 76 0.022
cytosolic calcium ion transport GO:0060401 2 0.022
defense response GO:0006952 300 0.022
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
regulation of cell division GO:0051302 72 0.022
cellular ketone metabolic process GO:0042180 24 0.022
positive regulation of cellular component organization GO:0051130 156 0.022
morphogenesis of an epithelium GO:0002009 276 0.021
cell motility GO:0048870 251 0.021
camera type eye development GO:0043010 4 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
protein catabolic process GO:0030163 101 0.021
cytoskeleton dependent intracellular transport GO:0030705 44 0.021
macromolecule catabolic process GO:0009057 161 0.021
wnt signaling pathway GO:0016055 98 0.021
sensory organ morphogenesis GO:0090596 260 0.021
aromatic compound catabolic process GO:0019439 166 0.020
organelle assembly GO:0070925 198 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
acid secretion GO:0046717 1 0.020
sensory perception of pain GO:0019233 4 0.020
tissue morphogenesis GO:0048729 297 0.020
heterocycle catabolic process GO:0046700 166 0.020
regulation of intracellular transport GO:0032386 64 0.020
negative regulation of gene expression GO:0010629 387 0.020
negative regulation of developmental process GO:0051093 201 0.020
androgen metabolic process GO:0008209 1 0.019
cellular lipid metabolic process GO:0044255 83 0.019
retina development in camera type eye GO:0060041 4 0.019
cytosolic calcium ion homeostasis GO:0051480 11 0.019
steroid catabolic process GO:0006706 1 0.019
monocarboxylic acid transport GO:0015718 3 0.019
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.019
regulation of growth GO:0040008 233 0.018
microtubule based movement GO:0007018 51 0.018
growth GO:0040007 359 0.018
protein localization GO:0008104 284 0.018
response to heat GO:0009408 63 0.018
insecticide catabolic process GO:0046701 1 0.018
cell maturation GO:0048469 144 0.018
organic substance transport GO:0071702 257 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
response to carbohydrate GO:0009743 15 0.018
nitrogen compound transport GO:0071705 85 0.018
nucleoside phosphate catabolic process GO:1901292 110 0.018
eye morphogenesis GO:0048592 260 0.018
thermosensory behavior GO:0040040 19 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
cell cycle phase transition GO:0044770 140 0.018
wing disc morphogenesis GO:0007472 344 0.018
cell projection assembly GO:0030031 94 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
response to oxygen levels GO:0070482 59 0.017
leg disc morphogenesis GO:0007478 80 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
spindle organization GO:0007051 253 0.017
locomotory behavior GO:0007626 176 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
circadian rhythm GO:0007623 105 0.017
regulation of catalytic activity GO:0050790 185 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
telencephalon development GO:0021537 2 0.016
sleep GO:0030431 49 0.016
secretion by cell GO:0032940 101 0.016
sodium ion transport GO:0006814 22 0.016
cytoplasmic transport GO:0016482 130 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
larval behavior GO:0030537 42 0.016
regulation of nervous system development GO:0051960 248 0.016
axonogenesis GO:0007409 290 0.016
multicellular organismal aging GO:0010259 140 0.016
female mating behavior GO:0060180 30 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
synapse assembly GO:0007416 143 0.016
death GO:0016265 284 0.016
response to carbon dioxide GO:0010037 4 0.015
regulation of synapse organization GO:0050807 110 0.015
cilium organization GO:0044782 41 0.015
cellular chemical homeostasis GO:0055082 40 0.015
regulation of catabolic process GO:0009894 170 0.015
multicellular organism growth GO:0035264 46 0.015
regulation of behavior GO:0050795 75 0.015
calcium ion transport into cytosol GO:0060402 2 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
eye development GO:0001654 323 0.015
response to drug GO:0042493 17 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
imaginal disc derived leg morphogenesis GO:0007480 80 0.015
developmental growth GO:0048589 280 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
organophosphate metabolic process GO:0019637 195 0.015
positive regulation of catabolic process GO:0009896 105 0.015
oxoacid metabolic process GO:0043436 103 0.015
compound eye development GO:0048749 307 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
body morphogenesis GO:0010171 2 0.015
compound eye morphogenesis GO:0001745 249 0.015
convergent extension GO:0060026 2 0.015
negative regulation of homeostatic process GO:0032845 2 0.015
regulation of protein metabolic process GO:0051246 256 0.015
ribose phosphate metabolic process GO:0019693 145 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
epiboly GO:0090504 2 0.014
cellular response to monosaccharide stimulus GO:0071326 2 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
response to purine containing compound GO:0014074 12 0.014
protein modification process GO:0036211 438 0.014
negative regulation of behavior GO:0048521 8 0.014
microtubule based transport GO:0010970 42 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
muscle organ development GO:0007517 127 0.014
regulation of hydrolase activity GO:0051336 97 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
response to lipopolysaccharide GO:0032496 4 0.014
regulation of feeding behavior GO:0060259 16 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
pigment metabolic process involved in pigmentation GO:0043474 33 0.014
cellular response to organic substance GO:0071310 132 0.014
rhodopsin mediated signaling pathway GO:0016056 21 0.014
glial cell differentiation GO:0010001 35 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
xenobiotic catabolic process GO:0042178 1 0.014
vesicle mediated transport GO:0016192 381 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
amine metabolic process GO:0009308 12 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
phagocytosis GO:0006909 215 0.013
sensory perception of sound GO:0007605 56 0.013
forebrain development GO:0030900 2 0.013
lipid biosynthetic process GO:0008610 46 0.013
nucleotide metabolic process GO:0009117 161 0.013
wound healing spreading of cells GO:0044319 2 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
detection of visible light GO:0009584 38 0.013
oocyte maturation GO:0001556 3 0.013
purine containing compound metabolic process GO:0072521 155 0.013
cellular macromolecule localization GO:0070727 220 0.013
cellular cation homeostasis GO:0030003 38 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
developmental maturation GO:0021700 172 0.013
regulation of cell development GO:0060284 215 0.012
regulation of anatomical structure size GO:0090066 163 0.012
response to organophosphorus GO:0046683 2 0.012
mechanosensory behavior GO:0007638 12 0.012
gtp metabolic process GO:0046039 72 0.012
endocytosis GO:0006897 310 0.012
regulation of synaptic transmission GO:0050804 69 0.012
protein localization to organelle GO:0033365 82 0.012
protein transport GO:0015031 155 0.012
response to mechanical stimulus GO:0009612 28 0.012
negative regulation of sequestering of calcium ion GO:0051283 2 0.012
regulation of molecular function GO:0065009 217 0.012
cellular protein modification process GO:0006464 438 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
rna processing GO:0006396 147 0.012
positive regulation of intracellular transport GO:0032388 42 0.012
carbohydrate metabolic process GO:0005975 82 0.012
pigmentation GO:0043473 75 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
camera type eye morphogenesis GO:0048593 2 0.012
startle response GO:0001964 16 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.012
open tracheal system development GO:0007424 204 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
intracellular signal transduction GO:0035556 300 0.012
cilium morphogenesis GO:0060271 39 0.012
hormone metabolic process GO:0042445 33 0.012
stem cell division GO:0017145 69 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
fat soluble vitamin metabolic process GO:0006775 1 0.012
ribonucleotide catabolic process GO:0009261 109 0.011
cell death GO:0008219 279 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
stem cell proliferation GO:0072089 88 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
axis specification GO:0009798 167 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
dna metabolic process GO:0006259 227 0.011
carboxylic acid transport GO:0046942 18 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
positive regulation of neurotransmitter transport GO:0051590 2 0.011
intercellular transport GO:0010496 2 0.011
single organism cellular localization GO:1902580 180 0.011
appendage development GO:0048736 401 0.011
anion transport GO:0006820 41 0.011
behavioral response to pain GO:0048266 3 0.011
leg disc development GO:0035218 92 0.011
organelle fission GO:0048285 340 0.011
regulation of cell proliferation GO:0042127 163 0.011
cellular response to ketone GO:1901655 17 0.011
cell recognition GO:0008037 102 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
connective tissue development GO:0061448 3 0.011
embryonic morphogenesis GO:0048598 206 0.011
notch signaling pathway GO:0007219 120 0.011
potassium ion transport GO:0006813 20 0.011
anatomical structure homeostasis GO:0060249 97 0.011
signal release GO:0023061 49 0.011
male gamete generation GO:0048232 201 0.010
water homeostasis GO:0030104 3 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
organic anion transport GO:0015711 28 0.010
regulation of camp biosynthetic process GO:0030817 12 0.010
proboscis extension reflex GO:0007637 6 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
response to reactive oxygen species GO:0000302 24 0.010
regulation of vesicle mediated transport GO:0060627 59 0.010
regulation of protein localization GO:0032880 76 0.010
hormone catabolic process GO:0042447 3 0.010
regulation of endocytosis GO:0030100 37 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010

Tre disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.358
lower respiratory tract disease DOID:0050161 0 0.358
bronchial disease DOID:1176 0 0.358
disease of anatomical entity DOID:7 0 0.358
renal tubular transport disease DOID:447 0 0.028
kidney disease DOID:557 0 0.028
urinary system disease DOID:18 0 0.028
bronchiectasis DOID:9563 0 0.023
cardiovascular system disease DOID:1287 0 0.018
hypertension DOID:10763 0 0.013
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013
essential hypertension DOID:10825 0 0.013
primary ciliary dyskinesia DOID:9562 0 0.013