Drosophila melanogaster

54 known processes

Srp54 (Dmel_CG4602)

CG4602 gene product from transcript CG4602-RA

(Aliases: anon-EST:Liang-2.16,CG4602,SRp54,dSRp54,Dmel\CG4602,clone 2.16,p75)

Srp54 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 147 0.619
regulation of mrna processing GO:0050684 71 0.362
mrna metabolic process GO:0016071 124 0.353
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.351
dna damage checkpoint GO:0000077 78 0.338
regulation of meiosis GO:0040020 3 0.331
cell cycle checkpoint GO:0000075 95 0.325
regulation of cell cycle process GO:0010564 181 0.283
g2 dna damage checkpoint GO:0031572 69 0.273
embryo development ending in birth or egg hatching GO:0009792 152 0.267
Worm
negative regulation of cell cycle GO:0045786 116 0.256
rna splicing via transesterification reactions GO:0000375 73 0.241
regulation of cell cycle GO:0051726 291 0.211
negative regulation of gene expression GO:0010629 387 0.209
Worm
heterocycle catabolic process GO:0046700 166 0.202
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.195
negative regulation of cell cycle process GO:0010948 109 0.191
dna integrity checkpoint GO:0031570 81 0.188
mitotic cell cycle checkpoint GO:0007093 88 0.188
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.171
cellular response to dna damage stimulus GO:0006974 223 0.165
cell division GO:0051301 248 0.152
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.134
mitotic g2 m transition checkpoint GO:0044818 70 0.129
regulation of mrna metabolic process GO:1903311 72 0.120
tube morphogenesis GO:0035239 191 0.116
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.115
larval development GO:0002164 104 0.114
Worm
negative regulation of biosynthetic process GO:0009890 277 0.112
negative regulation of mitotic cell cycle GO:0045930 109 0.111
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.110
regulation of mrna splicing via spliceosome GO:0048024 64 0.108
mitotic dna integrity checkpoint GO:0044774 75 0.107
mrna processing GO:0006397 104 0.106
purine nucleoside catabolic process GO:0006152 112 0.104
tube development GO:0035295 244 0.103
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.100
regulation of mitotic cell cycle GO:0007346 190 0.099
embryonic morphogenesis GO:0048598 206 0.095
response to lipopolysaccharide GO:0032496 4 0.092
snrna metabolic process GO:0016073 14 0.091
mitotic g2 dna damage checkpoint GO:0007095 69 0.091
mitotic dna damage checkpoint GO:0044773 74 0.090
endocytosis GO:0006897 310 0.089
Worm
body morphogenesis GO:0010171 2 0.086
biological adhesion GO:0022610 138 0.079
homeostatic process GO:0042592 199 0.078
cell cycle phase transition GO:0044770 140 0.078
anatomical structure homeostasis GO:0060249 97 0.078
negative regulation of translation GO:0017148 28 0.076
negative regulation of cellular protein metabolic process GO:0032269 85 0.075
intracellular signal transduction GO:0035556 300 0.074
secretion GO:0046903 109 0.073
sensory organ morphogenesis GO:0090596 260 0.072
regulation of cell division GO:0051302 72 0.070
organophosphate metabolic process GO:0019637 195 0.067
aromatic compound catabolic process GO:0019439 166 0.067
nuclear transcribed mrna catabolic process GO:0000956 24 0.066
negative regulation of cellular metabolic process GO:0031324 382 0.066
rna catabolic process GO:0006401 37 0.066
cellular nitrogen compound catabolic process GO:0044270 165 0.064
negative regulation of rna metabolic process GO:0051253 251 0.064
positive regulation of developmental process GO:0051094 143 0.062
pole plasm oskar mrna localization GO:0045451 46 0.061
epithelial cell differentiation GO:0030855 322 0.061
posttranscriptional regulation of gene expression GO:0010608 145 0.060
Worm
organic cyclic compound catabolic process GO:1901361 168 0.060
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.056
germarium derived egg chamber formation GO:0007293 101 0.055
vesicle mediated transport GO:0016192 381 0.055
Worm
anterior posterior pattern specification GO:0009952 136 0.054
regulation of cell differentiation GO:0045595 302 0.053
small gtpase mediated signal transduction GO:0007264 88 0.053
mrna cis splicing via spliceosome GO:0045292 1 0.053
reproductive structure development GO:0048608 74 0.052
negative regulation of nucleic acid templated transcription GO:1903507 240 0.052
regulation of mrna 3 end processing GO:0031440 7 0.052
positive regulation of cellular biosynthetic process GO:0031328 316 0.051
negative regulation of cellular biosynthetic process GO:0031327 277 0.050
regulation of protein metabolic process GO:0051246 256 0.049
nitrogen compound transport GO:0071705 85 0.049
organic substance catabolic process GO:1901575 308 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.046
compound eye morphogenesis GO:0001745 249 0.045
death GO:0016265 284 0.045
nucleobase containing compound catabolic process GO:0034655 165 0.044
positive regulation of phosphate metabolic process GO:0045937 139 0.044
growth GO:0040007 359 0.043
cellular response to organic cyclic compound GO:0071407 32 0.042
regulation of cell proliferation GO:0042127 163 0.042
columnar cuboidal epithelial cell development GO:0002066 249 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
chromatin modification GO:0016568 147 0.042
mrna catabolic process GO:0006402 33 0.042
gonad development GO:0008406 50 0.041
regulation of cellular protein metabolic process GO:0032268 243 0.041
positive regulation of phosphorus metabolic process GO:0010562 139 0.041
phosphorylation GO:0016310 294 0.041
cell adhesion GO:0007155 136 0.040
camera type eye development GO:0043010 4 0.039
cellular catabolic process GO:0044248 372 0.039
regulation of response to external stimulus GO:0032101 115 0.039
eye development GO:0001654 323 0.039
phagocytosis GO:0006909 215 0.039
regulation of cell cycle phase transition GO:1901987 130 0.039
response to other organism GO:0051707 293 0.039
positive regulation of cell communication GO:0010647 250 0.038
positive regulation of response to stimulus GO:0048584 323 0.037
segmentation GO:0035282 207 0.037
muscle organ development GO:0007517 127 0.037
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.036
spindle organization GO:0007051 253 0.036
positive regulation of mrna processing GO:0050685 4 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.035
positive regulation of protein metabolic process GO:0051247 128 0.035
mrna splicing via spliceosome GO:0000398 73 0.034
compound eye development GO:0048749 307 0.034
response to bacterium GO:0009617 198 0.034
regulation of anatomical structure morphogenesis GO:0022603 242 0.034
catabolic process GO:0009056 409 0.033
response to abiotic stimulus GO:0009628 341 0.033
regionalization GO:0003002 416 0.033
mitotic cell cycle phase transition GO:0044772 138 0.033
oocyte anterior posterior axis specification GO:0007314 72 0.032
regulation of meiotic cell cycle GO:0051445 9 0.032
rna splicing GO:0008380 83 0.032
negative regulation of cell cycle phase transition GO:1901988 103 0.032
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
reproductive system development GO:0061458 74 0.031
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.030
protein modification process GO:0036211 438 0.030
stem cell differentiation GO:0048863 117 0.030
centrosome organization GO:0051297 163 0.030
ribonucleoside catabolic process GO:0042454 112 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
eye morphogenesis GO:0048592 260 0.028
defense response to bacterium GO:0042742 178 0.028
embryonic axis specification GO:0000578 107 0.028
regulation of small gtpase mediated signal transduction GO:0051056 93 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
embryonic pattern specification GO:0009880 174 0.028
response to organic substance GO:0010033 284 0.027
ras protein signal transduction GO:0007265 88 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
rna localization GO:0006403 115 0.027
axis specification GO:0009798 167 0.027
pole plasm assembly GO:0007315 61 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
response to external biotic stimulus GO:0043207 293 0.025
positive regulation of ras protein signal transduction GO:0046579 43 0.025
regulation of translation GO:0006417 56 0.025
gene silencing GO:0016458 138 0.024
Worm
purine containing compound metabolic process GO:0072521 155 0.024
pole plasm mrna localization GO:0019094 49 0.024
cell motility GO:0048870 251 0.024
digestive system development GO:0055123 149 0.024
blastoderm segmentation GO:0007350 159 0.023
translation GO:0006412 69 0.022
multicellular organismal aging GO:0010259 140 0.022
muscle structure development GO:0061061 224 0.022
cell migration GO:0016477 238 0.022
regulation of catalytic activity GO:0050790 185 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.022
retina development in camera type eye GO:0060041 4 0.021
programmed cell death GO:0012501 257 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
anterior posterior axis specification embryo GO:0008595 103 0.021
positive regulation of exocytosis GO:0045921 4 0.021
regulation of catabolic process GO:0009894 170 0.021
regulation of developmental growth GO:0048638 174 0.021
actin cytoskeleton organization GO:0030036 206 0.020
intracellular mrna localization GO:0008298 66 0.020
posttranscriptional gene silencing by rna GO:0035194 45 0.020
Worm
anterior posterior axis specification GO:0009948 109 0.020
aging GO:0007568 143 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
guanosine containing compound catabolic process GO:1901069 74 0.019
regulation of molecular function GO:0065009 217 0.019
synapse organization GO:0050808 196 0.019
response to radiation GO:0009314 155 0.019
wing disc morphogenesis GO:0007472 344 0.019
regulation of cell shape GO:0008360 113 0.019
nucleoside catabolic process GO:0009164 112 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
positive regulation of peptidase activity GO:0010952 29 0.018
positive regulation of gene expression GO:0010628 290 0.018
meiotic cell cycle GO:0051321 171 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
cell death GO:0008219 279 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
positive regulation of developmental growth GO:0048639 62 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
immune system process GO:0002376 347 0.017
mrna 3 end processing GO:0031124 28 0.017
nucleotide metabolic process GO:0009117 161 0.017
oocyte development GO:0048599 124 0.017
exocrine system development GO:0035272 162 0.017
purine containing compound catabolic process GO:0072523 112 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
proteolysis GO:0006508 192 0.017
tripartite regional subdivision GO:0007351 103 0.017
positive regulation of defense response GO:0031349 59 0.017
appendage development GO:0048736 401 0.017
guanosine containing compound metabolic process GO:1901068 74 0.016
organic substance transport GO:0071702 257 0.016
protein targeting GO:0006605 64 0.016
regulation of proteolysis GO:0030162 87 0.016
positive regulation of molecular function GO:0044093 136 0.016
actin filament based process GO:0030029 220 0.016
regulation of immune system process GO:0002682 176 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
gtp metabolic process GO:0046039 72 0.016
regulation of protein deacetylation GO:0090311 2 0.016
rna 3 end processing GO:0031123 45 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
cellular protein modification process GO:0006464 438 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
pole plasm rna localization GO:0007316 52 0.015
response to oxygen containing compound GO:1901700 200 0.015
meiotic nuclear division GO:0007126 151 0.015
eye photoreceptor cell development GO:0042462 81 0.015
positive regulation of immune system process GO:0002684 68 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
diterpenoid biosynthetic process GO:0016102 1 0.014
regulation of organelle organization GO:0033043 196 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
posttranscriptional gene silencing GO:0016441 46 0.014
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
ovarian follicle cell development GO:0030707 248 0.014
regulation of phosphatase activity GO:0010921 3 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
macromolecule catabolic process GO:0009057 161 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
apoptotic process GO:0006915 159 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
negative regulation of developmental process GO:0051093 201 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
regulation of synapse organization GO:0050807 110 0.014
striated muscle cell differentiation GO:0051146 90 0.013
single organism catabolic process GO:0044712 228 0.013
regulation of apoptotic process GO:0042981 130 0.013
cellular macromolecule localization GO:0070727 220 0.013
mitotic spindle elongation GO:0000022 81 0.013
response to biotic stimulus GO:0009607 294 0.013
sex differentiation GO:0007548 81 0.013
regulation of gene silencing GO:0060968 63 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
regulation of multi organism process GO:0043900 131 0.013
positive regulation of signal transduction GO:0009967 223 0.013
cellular response to organic substance GO:0071310 132 0.013
wound healing GO:0042060 75 0.013
receptor mediated endocytosis GO:0006898 21 0.012
Worm
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.012
mitotic spindle organization GO:0007052 220 0.012
taxis GO:0042330 304 0.012
lipid localization GO:0010876 54 0.012
Worm
photoreceptor cell differentiation GO:0046530 170 0.012
regulation of nuclear division GO:0051783 58 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
alternative mrna splicing via spliceosome GO:0000380 60 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
cellular response to lipid GO:0071396 20 0.012
appendage morphogenesis GO:0035107 397 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
amine metabolic process GO:0009308 12 0.011
intermediate filament cytoskeleton organization GO:0045104 1 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
ribonucleoprotein complex assembly GO:0022618 23 0.011
nucleoside metabolic process GO:0009116 127 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
ovarian follicle cell cell adhesion GO:0007299 4 0.011
chromosome organization GO:0051276 360 0.011
gastrulation GO:0007369 70 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
salivary gland development GO:0007431 162 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
positive regulation of small gtpase mediated signal transduction GO:0051057 43 0.011
gtp catabolic process GO:0006184 72 0.011
negative regulation of gene silencing by rna GO:0060967 9 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
negative regulation of cell communication GO:0010648 223 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
developmental growth GO:0048589 280 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
regulation of hydrolase activity GO:0051336 97 0.010

Srp54 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.090
nervous system disease DOID:863 0 0.028
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011